Statistika Ukrayini最新文献

{"title":"The Pharmaceutical Industry in New EU Member States: A Statistical Comparison with Germany. Lessons for Ukraine","authors":"D. Honcharenko","doi":"10.31767/su.2(93)2021.02.03","DOIUrl":"https://doi.org/10.31767/su.2(93)2021.02.03","url":null,"abstract":"Pharmaceutical production is a strategic sector of the EU economy. The authorities of Central and Eastern Europe (CEE) countries that became EU members in 2004 have been building up domestic pharmaceutical industries for purposes of production and distribution of medical drugs (MDs) and medical products (MPs), on the one hand, and government assistance to business entities and public procurement, on the other. The article’s objective is to assess the change in economic performance of the pharmaceutical industry in Poland, Hungary and Czechia after their accession to EU, to make a comparative statistical analysis with Germany, the leader of pharmaceutical production in EU, and to reveal key problems of this industry development in CEE countries, in order to elaborate recommendations for Ukraine on replication of best practices and avoidance of potential risks. \u0000Results of research show that pharmaceutical producers (group 54 SITC Rev.4) in CEE countries have been focusing mostly on EU market, with Germany being their main partner. The turnover of high tech pharmaceutical goods in CEE countries has significantly grown after the accession to EU, along with the significantly grown imports of these goods and the increasing negative trade balance. Pharmaceutical companies in CEE countries could increase the salaries and the apparent labor productivity, but the gap between them and Germany in salary and productivity terms still remains too wide. In the studied CEE countries there has been significant increase in pharmaceutical R&D spending, but its estimated share remains quite low compared with average figures for EU (16.1%) and Germany (25.6%). \u0000It is substantiated that because the future Agreement between the European Community and Ukraine on conformity assessment and acceptance of industrial products (ACAA agreement, or “Industrial visa-free regime”), which is being negotiated right now, will cover the pharmaceutical industry, the Ukrainian pharmaceutics will gain benefits only given the consolidated endogenous capacities of the industry and firmly established advantages of localization providing stimuli for European companies to create production facilities and R&D centers in Ukraine (including ones for contract-based R&D and productions). It is demonstrated that the inflow of investment and technologies from European pharmaceutical companies is capable of accelerating production start-up and exports of MDs and MPs (as time need not be lost for setting up all the links of the chain), thus adding up to the assets of Ukrainian producers (through transfer of knowledge and skills), but all the above cannot compensate for domestic efforts aimed at creating tangible and intangible assets in the industry. Given its Eurointegration context, Ukraine needs to pursue the policy of increasing the industry’s endogenous capacities and rely on the comprehensive approach (instead of focusing on MDs and MPs) that will cover the following key areas: biological and c","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45489522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The COVID-19 Pandemic in Ukraine: Process Evaluation, Opinion Analysis","authors":"Z. Palian, O. I. Zolotenkova, A. Savchenko","doi":"10.31767/su.2(93)2021.02.07","DOIUrl":"https://doi.org/10.31767/su.2(93)2021.02.07","url":null,"abstract":"The SARS-CoV-2 coronavirus pandemic has proved to be a real test of survival for modern humanity. The global crisis has affected not only the health care system, but also the entire social sphere. For the second year in a row, the world economy is under stress, and countries around the world are assessing and forecasting the scale of economic losses, trying to determine the size of direct and indirect demographic losses. It’s impossible to coordinate the implementation of anti-epidemic measures and disease prevention without adequate response and support from the population. And this requires an analysis of social behavior, its motivation and attitude to the relevant actions of state and local authorities. \u0000The article considers the current trends in the spread of SARS-CoV2 infection in Ukraine and in some European countries. Seasonal fluctuations and cyclical changes in the prevalence of this disease and the number of deaths caused by coronavirus are analyzed. The 7-day seasonal fluctuations are to some extent explained by the peculiarities of the initial registration of such events in Ukraine. After all, some of the test results and medical certificates of death caused by coronavirus disease are submitted to the relevant authorities with some delay. There is a multi-day registration lag after the weekend, when most instances do not work, so the input information is processed with a delay. \u0000The statistical estimates of expected daily number of infected with COVID-19 virus and deaths from this cause (data of the National Security and Defense Council of Ukraine for March-December 2020 and January 2021) are based on an analysis of these trends in the context of effectiveness of preventive measures from “quarantine in free day” up to a hard lockdown. \u0000The article provides a quantitative assessment of the population's response to anti-epidemic measures of government agencies. Database of research comprised a series of opinion polls within the monitoring “Ukraine under quarantine” and “Assessment of Healthcare”, the sociological group “Rating” for 2020–2021. The results of the statistical analysis of psycho-emotional state of the population during the COVID-crisis showed significant differences in the responses of certain respondents groups by age, gender and place of residence. \u0000Using non-parametric methods of statistics, the level of Ukrainian population trust in international and domestic medical institutions, as well as in information coming from various sources was estimated. It turned out that respondents are almost 20 times more willing to read news from regular Internet resources than from the official website of the Ministry of Health of Ukraine and rely more on WHO data. \u0000In the perspective of further research, a statistical analysis of the demographic consequences of the spread of SARS-CoV2 infection in Ukraine is planned.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48826091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Assessment of the Demographic Security of the Republic of Belarus","authors":"E. Е. Sharilova","doi":"10.31767/su.1(92)2021.01.09","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.09","url":null,"abstract":"Security is a necessary component of the life of individuals and society as a whole. One of the most important components of the national security is demographic security, which achievement in the Republic of Belarus means the neutralization of threats such as depopulation, population ageing, degradation of the family institute and unregulated migration processes. \u0000The article presents a methodology for a comprehensive statistical assessment of the demographic security of the Republic of Belarus for 2000–2019, based on of the dualistic approach to the interpretation of this concept, proposed by the author, namely: real and potential demographic security. The real demographic security is the degree of protection from demographic threats in the current social circumstances, which is largely determined by the compliance of government policy with demographic realities. \u0000The proposed methodology for a comprehensive assessment of demographic security includes five consecutive phases: formulating a definition of “demographic security”, identifying demographic threats, building a set of indicators for a comprehensive statistical assessment of demographic security, assessing the effect of demographic threats (general and real), and, finally, assessing the degree of protection from demographic threats (real demographic security). \u0000The structural components of the overall strength of demographic threats are the degrees of real demographic security and the real strength of the threats. The following trend in these values was observed in the Republic of Belarus in 2000-2019: an increase in the degree of real demographic security in parallel with a decrease in the degree of real combined strength of threats in 2015 compared to 2000, giving way to a decrease in the first indicator and an increase in the second one in 2019. It follows that the achievements of the Republic of Belarus in demographic security were short-lived. For a systemic change in the negative trends, it is necessary to form a favorable demographic situation through the active use of educational and propagandist measures.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47260044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multilevel Modelling of Under-Five Time to Death, and Risk Factors","authors":"A. Argawu","doi":"10.31767/su.1(92)2021.01.04","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.04","url":null,"abstract":"Under-five mortality is a leading indicator of child health and overall development of a country. Sub-Saharan Africa remains the region with the highest under-5 mortality rate in the world, with 1 child in 13 dying before his or her fifth birthday. Half of all under-five deaths in 2019 occurred in just five countries: Nigeria, India, Pakistan, the Democratic Republic of the Congo, and Ethiopia. In Ethiopia, as the 2016 Ethiopia Demographic and Health Survey (EDHS) report showed that the under-five mortality declined from 166 deaths per 1,000 live births in 2000 to 67 deaths per 1,000 live births in 2019 mini EDHS report (60% decreasing rate). However, there are regional disparities problems on under-five children mortality in Ethiopia. Thus, the major purpose of this study was to model the multilevel effects of U5 child time to death, and to determine the risk factors for child’s death based on the last full report (2016 EDHS). The data were analysed using descriptive statistics, stratified Cox proportional hazards regression and multilevel parametric survival models. In the study, 635 (6.1%) U5 deaths have observed from 10,331 children. And, the overall probability of survival was 0.93. Results obtained by fitting both stratified Cox proportional hazards regression and lognormal parametric fixed-effect models: sex of child, type of birth, birth order, size (weight) of child at birth, months of breastfeeding, number of U5 and five children, family size, wealth index, frequency of listening radio, place of delivery place of residence, and geographical region were found to be significant factors for U5 children death or estimated mean survival time. Furthermore a high risk death of U5 children was found to be associated with male children, twined children, ≤ 6 months breastfeeding children, few number of children in the home, children from small family size, children average weight below, children from poor families, private health sectors delivered children, children from mothers didn’t not listen radio, children from rural areas, children from Afar, Somali and Harari regional states. In the lognormal parametric random effects model, 1.7 and 0.9 estimated variations were observed among regional and household cluster levels on U5 children mean survival times. The researchers recommended that governments, and other concerned bodies should give special supports for mothers whose children are at high risk of death.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47372406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Specifics of the Investment Attractiveness at Company Level","authors":"L. Plakhotnikova, Т. Bulakh","doi":"10.31767/su.1(92)2021.01.03","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.03","url":null,"abstract":"Foreign investment is an essential factor in increasing the competitiveness of the national economy in our days. Investment is considered to be the main prerequisite for the social development, but the investment process faces many obstacles and problems not allowing to make it efficient and orderly. \u0000Intensification of investment processes is a priority objective of companies on the way to the sustainable development and enhanced competitive positions in the market environment. The investment attractiveness has critical significance in it, as its dynamism depends on the company’s ability to meet the terms of potential investors. \u0000In focus of the article are issues of attracting foreign capital as an important factor in accelerating technical progress and improving the company performance. The essence, types and significance of foreign investment in the context of globalization processes, relationships between the investment climate characteristics and the company competitiveness are determined. Factors of the investment capital reproduction increasing the capital cost at two levels, macro- and microeconomic, are discussed. \u0000An analysis of the performance and prospects of foreign investment in the Ukrainian business sector in the context of financial and economic globalization is made; the need for investment to ensure the company competitiveness in the conditions of economic crisis is justified. \u0000Approaches to the classification of factors determining investment climate and investment attractiveness were improved, which are defined at the macroeconomic and microeconomic level and involve their relationship and interaction. An analysis of interactions between transformation processes in the Ukrainian economy and investment activities revealed a correlation of the investment climate and the investment level with the company competitiveness on the market.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47259847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Registers of the Education System in European Countries: Useful Practices for Ukraine","authors":"M. Puhachova","doi":"10.31767/su.1(92)2021.01.06","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.06","url":null,"abstract":"Education sectors at country level rely on the circulation of large scopes of information pertaining to education institutions, research institutions, pupils and students, teaching staff, researchers, education diploma or certificates etc. Therefore, the register systems allowing to systematize this information, file it in a convenient form, edit and communicate to physical persons whom these data belong, and to support administrative decision making constitute a necessary tool for the satisfaction of information needs of the modern society. The registers (databases) of the education sector are integral components of the online information resource system in developed countries, which usually consists of the two subsystems: registers containing information about the population, and business registers.     \u0000The greatest progress in creating online information resource system, according to experts from international organizations, has been achieved in North European countries. These countries have also become pioneers in carrying out population censuses on the basis of registers, including ones in the education sector.   \u0000The article’s objective is to sum up the practices of North European countries in creating and operating electronic information resource systems in the education sector for its adaptation in the Ukrainian realities.   \u0000The education registers (databases) of Denmark, the Netherlands, Norway, and Estonia are discussed, with making comparison of register systems in six North European countries. It is stressed that Denmark has created the most elaborate register system operated by the line ministry and the statistical office, in the Netherlands and Norway only two education registers exist, containing the necessary information on all the education levels of the population, Estonia has the single information system for the education, and in Sweden and Finland separate registers for each education level have been created. All the above mentioned register systems in education have sufficient information content, and they are continuously improved. And most importantly, these education registers (databases) in all the studied countries are linked by personal identifiers of individuals with other registers containing information about the population.     \u0000The process of creating the Unified State Electronic Database on Education in Ukraine is analyzed, with elaborating on the registers included in this system and their content. Conclusions and recommendations on improvements and further developments in education registers of Ukraine and their links with other population-specific registers are made by summing up the practices of creating electronic information resource systems in North European countries.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45960900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality in Metropolises of Ukraine: Historical Parallels with the Study of Yu. O. Korchak-Chepurkivsky","authors":"N. Ryngach","doi":"10.31767/su.1(92)2021.01.05","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.05","url":null,"abstract":"The purpose of this paper is to make a comparative analysis (find historical parallels) of the situation with mortality causes in four cities of Ukraine in 1923–1929 and in our time, by comparing the mortality structure in 1926 and 2019, to identify structural changes and make assumptions regarding their determinants. Based on data from statistical tables of mortality in the four largest cities of the Ukrainian Socialist Soviet Republic (Kyiv, Kharkiv, Dnipropetrovsk, and Odessa) for 1923–1929 and data from the State Statistics Service of Ukraine for 2019 on the distribution of deaths by death cause in the same cities and in Ukraine, the structural shares by main classes were calculated (according to the current classifications). Changes in the contribution of various causes of death to the mortality of the urban population are estimated. The overall progress (the advancement of medical science and practice, the improvement of living conditions (including sanitation and hygiene) and quality of life, the increased population’s awareness of health issues and access to medical care, etc.), immunization programs, the development and production of effective drugs have significantly reduced the mortality and transformed its structure. \u0000It is shown that the list of the leading causes, especially their ranks, given in the research of Yu. O. Korchak-Chepurkivsky, differed significantly from the analogous list for modern metropolises of Ukraine. In contrast to the situation in the four largest Ukrainian cities in 2019, with the majority of deaths caused by diseases of the circulatory system (about 65%), almost the same total share (67.4%) of deaths in the above cities in 1926 was determined by five classes (infectious or communicable diseases, diseases of the respiratory and digestive organs, cardiovascular diseases, and diseases of the nervous system and sense organs). The largest share of deaths in the four largest cities of the Ukrainian Socialist Soviet Republic was found to be caused by infectious and parasitic diseases (over 27%). Given that part of the infectious pathology (the diseases of the digestive system and nervous system in the first place) was registered by the then nomenclature in other classes, their contribution to the totality of deaths can be assessed as more significant (at least by 10–15%). \u0000The structural share of mortality from infectious and parasitic diseases in the four largest cities has decreased from 27% altogether to nearly 2%. There was a significant transformation in the spectrum of causes: while in 1926 high mortality was due to scarlet fever, whooping cough, typhoid fever and paratyphoid fever evolved to almost zero, in our time its significant part was caused by a new pathology, a disease caused by the human immunodeficiency virus (HIV). At the same time, the significance of tuberculosis as a cause of death is a striking difference between the mortality pattern in Ukrainian cities and the situation in modern developed c","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44949232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate Change Statistics: European Experience and National Assessment","authors":"O. Osaulenko, T. Kobylynska","doi":"10.31767/su.1(92)2021.01.01","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.01","url":null,"abstract":"Climate change is one of the most serious threats to the society, economy and environment in the whole world and Ukraine in particular. The central objective for the environmental statistics today is to perform the sound statistical assessment, to develop or improve new or existing approaches to building up the system for accounting of the indicators measuring climate change and adaptation to it. The improvement or development of existing or new methodologies and methods for the statistical accounting and assessment of climate change indicators is the only way for the production of information in a sound and comprehensive manner. It is argued that the statistical analysis allows deepening the grasp into the operation of a complex and dynamic phenomena as climate change, elaborate actions to reduce its adverse environmental effect, and eliminate adverse consequences of climate change for our planet.  \u0000It is found that the official statistics have been put the ever stronger focus on issues of environmental performance and climate change by concentrating on the development and improvement of methodologies and procedures for compilation of environmental accounts that are used for economic measurements of natural resources, energy, waste, water resources, air emissions, spending for environmental protection. It is stressed the United Nations Statistical Commission has adopted, at global level, the System of Environmental-Economic Accounting (SEEA) designed to provide important support to the development of statistics related with climate change by intensifying the effort in several dimensions of the complex economic and environmental accounting. The industry coverage of the climate change statistics is defined, with a detailed description of various approaches to the environmental accounting in which indicators of climate change are involved. The significance of the environmental-economic accounting (and the account of air emission of dangerous substances in particular) as the central source of data on greenhouse gas emissions in Ukraine is substantiated. \u0000In spite of many functions in the measurement of climate change, assigned to the national statistics system, the existing official statistics does not always employ its capacities for the assessment of climate change. By considering the statistics on climate change as a tool with impact on decision-making in this field, the authors outlined the areas of improvements in the accounting of climate and climate change.  ","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44524644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poland as a Priority Country for the Education Migration of Young Ukrainians","authors":"Н. B. Cherusheva, V. Parkhomenko","doi":"10.31767/su.1(92)2021.01.07","DOIUrl":"https://doi.org/10.31767/su.1(92)2021.01.07","url":null,"abstract":"Intensification of the integration processes in education helps increase the quality of the international education and enhance the striving of youth to receive education services abroad.  The economic cooperation of Ukraine with EU countries is gradually taking shape, resulting in the rapidly growing demand of Ukrainian students for education in European higher education establishments (HEEs). The European education system is a global leader in training highly skilled staff due to the implementation of dual training which founder was German. The practice of combined training and internship has spread across Europe and gained extreme popularity in Polish HEEs, thus laying grounds for the increasing demand for their graduates.    \u0000In focus of the article is the international education migration of young Ukrainians, first and foremost to Poland, with highlighting the advantages of training in this country that has been recognized as the most optimal one on the European area with respect to professional training. This is due to several reasons: first, the overwhelming majority of Ukrainian graduates from Polish HEEs showed professional competencies and mental fitness for work in companies and enterprises across EU; second, Poland is one of the most attractive foreign partners and investors of Ukraine, which promotes rapid development of collaborative Ukrainian-Polish projects. Poland has been working hard in the latest years to develop and improve the system of education services for foreigners, beginning with language courses for training of professionals with various qualification levels and scientific degrees. The received education services, apart from being an effective means for professional and individual development, can help in the carrier promotion at companies in Poland and beyond. The study covers a social-psychological and economic-statistical analysis of the education migration of Ukraine in the latest years, with determining a range of factors that caused one’s choice of other country for getting education services, and investigating the consequences of Ukrainians’ travels abroad for education purposes.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46813338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Statistical Modelling Approach for Guiding the Optimum Surgical Intervention of Breast Cancer","authors":"N. Kovtun, I. Motuziuk, R. Ganzha","doi":"10.31767/su.2(85)2019.02.05","DOIUrl":"https://doi.org/10.31767/su.2(85)2019.02.05","url":null,"abstract":"Breast cancer is most common tumour diagnosis for women worldwide. Over the last almost 40 years widespread adoption of mammographic screening has established Breast Conserving Surgery (BCS) followed by irradiation as the most practised treatment of choice. However, in absence of tools to determine the optimal quantum of tissue to be excised the debate continues for achieving a balance between the effectiveness of surgical intervention and the later stage personalisation of treatment, and so, a wide variation in practice is a common phenomenon globally. We attempt to introduce a definite measure that determines efficacy of BCS while protecting aesthetic value of life for Women affected with breast cancer. \u000074 mammography examinations and the surgical interventions of those women underwent for the management of breast cancer were used to compute the coefficient of lesion. In first step the lesion and the mammary gland proper are measured applying geometry. In the second step volume of tissue mass to be removed was calculated taking into account the measures from the 1st step and we present the coefficient of lesion mathematically. We empirically illustrated our methodological approach for determining the tissue mass to be excised. \u0000Conventionally, it is assumed that if the volume of tissues to be removed does not exceed 25% of the volume of the mammary gland, a Breast Conserving Surgery, is performed, however, our empirical illustration demonstrated that the established decision making parameter is not tenable for determining the extent / type of surgery undertaken. \u0000We have developed a coefficient aligned with the stage of the carcinoma and founded the base for developing a statistical (mathematical) model. Application of such a model accommodating tumour biology and patient characteristics shall not only provide intraoperative real time information to surgeons but also predict the prognosis of optimal surgical intervention of breast cancer. \u0000The next step is to develop a model using the data of the mammographic examination and the coefficient of breast lesion as covariates for determining the potentially effective volumes of surgical intervention needed, and plan reconstructive measures considering the effect of time on such intervention.","PeriodicalId":52812,"journal":{"name":"Statistika Ukrayini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45136169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}