Journal of Affective Disorders Reports最新文献

{"title":"A longitudinal study exploring paternal stress and well-being, maternal depressive symptoms, and the offspring’s later psychosocial functioning in adolescence and young adulthood","authors":"Marie Korhonen ,&nbsp;Raili Salmelin ,&nbsp;Mika Helminen ,&nbsp;Ilona Luoma ,&nbsp;Mirjami Mäntymaa ,&nbsp;Kaija Puura","doi":"10.1016/j.jadr.2026.101035","DOIUrl":"10.1016/j.jadr.2026.101035","url":null,"abstract":"<div><h3>Background</h3><div>The influence of the father’s well-being on child development has been increasingly studied, but longitudinal studies remain few. This study explores how paternal stress and well-being in the offspring’s middle childhood is associated with the child’s internalizing and externalizing problems and competence in adolescence and young adulthood. In addition, it explores the combined effect of paternal stress and maternal depressive symptoms (MDS) trajectories, on child outcomes.</div></div><div><h3>Method</h3><div>The longitudinal study started in 1989 in Tampere, Finland, and included 351 normal population primiparous mothers. MDS were screened prenatally, postnatally at 2 and 6 months, and when the index child was 4–5, 8–9, 16–17, and 27 years old. Fathers participated at the 8–9 years follow-up. The children completed questionnaires when they were 16–17 and 27 years old. Complete data were available from 106 adolescents and 81 young adults.</div></div><div><h3>Results</h3><div>The father’s long term health problems were associated with the child’s poorer competence in adolescence. The simultaneous high maternal depressive symptoms trajectory increased the risk. In young adulthood, the father’s poorer health and life satisfaction were associated with the offspring having a lower level of internalizing problems and better adaptive functioning. The MDS trajectory was not associated with the young adult’s outcomes.</div></div><div><h3>Limitations</h3><div>The sample size was moderate, and high-symptomatic cases were more common among drop-outs.</div></div><div><h3>Conclusions</h3><div>Exposure to paternal stress and poor well-being in middle childhood should be considered as an important risk factor for child development. On the other hand, (mild) childhood adversity may enhance psychosocial functioning in young adulthood.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101035"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The self-reported positive and negative effects of electroconvulsive therapy: an international survey","authors":"John Read ,&nbsp;Sue Cunliffe ,&nbsp;Sarah Hancock ,&nbsp;Christopher Harrop ,&nbsp;Lucy Johnstone ,&nbsp;Lisa Morrison","doi":"10.1016/j.jadr.2025.101008","DOIUrl":"10.1016/j.jadr.2025.101008","url":null,"abstract":"<div><h3>Background</h3><div>When assessing the efficacy and safety of any medical procedure the experiences of patients need to be considered. This paper adds to the growing body of studies asking recipients of electroconvulsive therapy about their treatment experiences.</div></div><div><h3>Methods</h3><div>Open questions about the positive and negative effects of ECT, in an online international survey, were responded to by 776 ECT recipients, from 41 countries.</div></div><div><h3>Results</h3><div>About half (48.8 %) spontaneously reported one or more positive effects and almost all (96.9 %) spontaneously reported one or more negative effects. About half (51.2 %) reported only negative effects, 45.6 % reported a mixture of positive and negative effects and 3.2 % reported only positive outcomes. Content analysis found that the most reported positive effects were: ‘Improved Mood’ (23.2 %), ‘Reduced Suicidality’ (12.6 %) and ‘Reduced Psychosis’ (3.1 %). The most reported negative effects were: ‘Memory Loss’ (81.6 %), ‘Cognitive Decline’ (29.0 %), ‘Headache’ (11.1 %), ‘Abused/Violated/Traumatised’ (7.9 %), ‘Fear/Anxiety’ (6.8 %), ‘Impaired Relationships’ (5.4 %), ‘Brain Damage’ (5.0 %), ‘Can’t Work’ (4.9 %) and ‘Pain’ (4.9 %).</div></div><div><h3>Limitations</h3><div>This convenience sample may have been biased towards those with negative or positive attitudes about ECT. Some of the negative and positive effects attributed to ECT may have been the result of other factors (such as illness and age, or placebo, respectively).</div></div><div><h3>Conclusions</h3><div>These results, in conjunction with previous studies, suggest the need for new, more robust, independent research into safety and efficacy. The safety component of such studies should probably include adverse effects beyond memory loss and cognitive decline.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101008"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PTSD symptoms, loneliness, and amygdala volumes during pandemic social distancing associated with risk of suicidal ideation in trauma survivors with and without pre-pandemic PTSD","authors":"Mak E Guenther ,&nbsp;Jackson Lewis ,&nbsp;Juvet Ashu Ebai ,&nbsp;Jon D Elhai ,&nbsp;Qin Shao ,&nbsp;Xin Wang ,&nbsp;Hong Xie","doi":"10.1016/j.jadr.2026.101030","DOIUrl":"10.1016/j.jadr.2026.101030","url":null,"abstract":"<div><h3>Objective</h3><div>The prolonged social distancing during the COVID-19 pandemic has been shown to worsen loneliness, posttraumatic stress disorder (PTSD) symptoms and suicidal thought, though the negative effects of COVID-19 pandemic-related isolation on survivors with previous traumatic experiences remain largely unexplored. The present study investigated how pandemic-related social isolation relates to PTSD symptoms, thwarted belongingness and perceived burdensomeness, loneliness, and amygdala volumes in pre-pandemic trauma survivors with and without PTSD diagnosis.</div></div><div><h3>Methods</h3><div>Sixty-two participants from a previous PTSD study were recruited during the pandemic to complete online surveys, including the Interpersonal Needs Questionnaire (INQ) for thwarted belongingness (INQ-TB) and perceived burdensomeness (INQ-PB) to assess perceived social isolation and risk of suicidal ideation, UCLA Loneliness Scale, and the PTSD Checklist-5 (PCL) for PTSD symptoms, the virtual PTSD diagnostic interview, and a structural MRI (sMRI) scan to measure amygdala and nuclei volumes. Pre-pandemic PTSD diagnosis record was also obtained.</div></div><div><h3>Results</h3><div>Pandemic PCL were positively associated with UCLA loneliness and INQ-PB scores. INQ-TB and UCLA loneliness scores were inversely associated with post-pandemic amygdala volumes, specifically in left basolateral, central and cortical nuclei. Pre-pandemic PTSD diagnosis was associated with higher INQ-PB scores and smaller volumes of right amygdala and its centromedial nuclei post pandemic.</div></div><div><h3>Conclusions</h3><div>These findings suggest severe PTSD symptoms and smaller amygdala were associated with high loneliness and potential risk of suicidal ideation during the COVID-19 pandemic in trauma survivors. Pre-pandemic PTSD diagnosis can predict potential risk of suicidal ideation and reduced amygdala and its nuclei volumes when individuals are exposed to further stress.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101030"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracking PMDD: A systematic review of intensive longitudinal evidence on psychosocial and behavioural risk factors for premenstrual dysphoric disorder","authors":"Samantha Trevaskis ,&nbsp;Yvonne Hartnett ,&nbsp;Akansha Naraindas ,&nbsp;Hannah Durand ,&nbsp;Jessica Bramham ,&nbsp;Sonya Deschênes","doi":"10.1016/j.jadr.2026.101057","DOIUrl":"10.1016/j.jadr.2026.101057","url":null,"abstract":"<div><h3>Background</h3><div>Premenstrual Dysphoric Disorder (PMDD) is seen by some as a severe form of PMS, which significantly impacts daily life. While psychosocial and behavioural factors are thought to influence symptom severity, prior research has relied on cross-sectional designs.</div></div><div><h3>Aims</h3><div>This systematic review aimed to (1) identify tools and measures used to assess psychosocial and behavioural risk or protective factors in relation to PMDD symptom severity, and (2) to examine relationships between psychosocial or behavioural risk factors and PMDD symptom severity, which have been identified using intensive longitudinal methods.</div></div><div><h3>Methods</h3><div>A protocol was pre-registered (PROSPERO ID: CRD42023410126) and MEDLINE, Web of Science, Embase, CINAHL, and PsycINFO were searched. Eligible studies included reproductive-age participants, validated PMDD measures and intensive longitudinal methodologies. Data were extracted independently and quality assessed using the JBI critical appraisal tool. Due to heterogeneity, narrative synthesis with effect direction plots was conducted.</div></div><div><h3>Results</h3><div>13,507 records were screened and 12 studies (N = 2486 participants) were included. Nine PMDD measurements were used, most commonly the Daily Record of Severity of Problems. Substantial heterogeneity in study design, inclusion/exclusion criteria, and calculation of PMDD variables limited comparability. Consistent evidence linked family history of PMS, dysmenorrhea, and earlier menarche to higher PMDD symptom severity. Associations with depression, daily stress, and exercise were mixed, while smoking showed no clear relationship.</div></div><div><h3>Conclusions</h3><div>Evidence suggests psychosocial and behavioural factors may influence PMDD severity, but methodological inconsistencies restrict conclusions. Standardised, DSM-aligned measures, broader inclusion criteria, and transparent reporting are essential to advance the field.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101057"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147599972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mistreatment during health facility-based childbirth and symptoms suggestive of postpartum depression in low resource settings","authors":"Meresa Berwo Mengesha ,&nbsp;Hagos Mehari Mezgebo ,&nbsp;Gessessew Teklebrhan Gebrehiwot ,&nbsp;Haftom Tesfay Gebremedhin ,&nbsp;Etsay Weldekidan Tsegay ,&nbsp;Natnael Etsay Assefa ,&nbsp;Abadi Hailay Atsbaha ,&nbsp;Hiluf Ebuy Abraha ,&nbsp;Zenawi Hagos Gufue","doi":"10.1016/j.jadr.2026.101055","DOIUrl":"10.1016/j.jadr.2026.101055","url":null,"abstract":"<div><h3>Introduction</h3><div>Postpartum depression (PPD) is a substantial public health concern among mothers in sub-Saharan Africa but may be underestimated due to limited screening and treatment. Mistreatment during facility-based childbirth has been associated with PPD in prior studies, yet evidence on which mistreatment types are linked to greater PPD symptom severity remains limited. This study assessed the association between mistreatment during facility childbirth and PPD symptoms.</div></div><div><h3>Methods</h3><div>A multi-center, cross-sectional study was conducted among 414 postpartum women recruited from selected urban public health facilities using stratified systematic random sampling. Binary logistic regression model was used to estimate adjusted odds of symptoms suggestive of PPD among women reporting mistreatment during childbirth. Poisson regression with robust standard errors was used to assess differences in Edinburgh Postnatal Depression Scale (EPDS) total scores according to reported exposure to specific forms of mistreatment. Adjusted measures with 95% confidence intervals (CIs) were reported, with statistical significance set at <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>Among the 400 postpartum women included in the final analysis, 15.00% (95% CI: 11.65%–18.88%) had symptoms suggestive of PPD. In adjusted analyses, expressed as adjusted mean ratios (aMRs), physical abuse (aMR = 1.37; 95% CI: 1.07–1.74), stigma and discrimination (aMR = 1.28; 95% CI: 1.06–1.54), verbal abuse (aMR = 1.12; 95% CI: 1.01–1.24), and poor provider rapport (aMR = 1.12; 95% CI: 1.00–1.25) were significantly associated with higher expected EPDS total scores. Physical restraint was not significantly associated with expected EPDS total scores (aMR = 1.34; 95% CI: 1.00–1.81).</div></div><div><h3>Conclusions</h3><div>PPD symptoms were more prevalent among women who reported mistreatment during facility-based childbirth, and symptom severity differed by type of mistreatment. Strengthening respectful maternity care, addressing inequities, and fostering supportive community environments may help reduce institutional violence and the burden of PPD symptoms.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101055"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147599955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Depression and its Associated Factors among Higher Socio-Economic Married Working Women in Bangladesh","authors":"Md. Imdadul Haque ,&nbsp;Tasnim Akter ,&nbsp;Md. Monir Hossain Shimul ,&nbsp;Roman Hossain ,&nbsp;Faisal Muhammad ,&nbsp;Md. Golam Dostogir Harun ,&nbsp;Md Zobaer Hasan ,&nbsp;ABM Alauddin Chowdhury","doi":"10.1016/j.jadr.2026.101062","DOIUrl":"10.1016/j.jadr.2026.101062","url":null,"abstract":"<div><h3>Background</h3><div>Mental health challenges among working women are increasingly recognized as critical human rights concerns that cut across geographical, cultural, and socioeconomic contexts. This study examined the prevalence and associated factors of depression among higher socioeconomic, married working women in Bangladesh.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 560 married working women employed in various organizations in Dhaka City between June and November 2023. Data were collected using a semi-structured questionnaire, and depressive symptoms were assessed using the CES-D Scale. Multivariable logistic regression analysis was performed to examine factors associated with depressive symptoms. Adjusted odds ratios (AORs) with 95% confidence intervals were reported.</div></div><div><h3>Results</h3><div>The mean age of participants was 35.66 ± 4.77 years. The prevalence of depression was 27.7%, of which 11.6% reported severe depressive symptoms and 16.1% reported moderate depressive symptoms. The likelihood of poor mental health was significantly higher among women who were consistently overloaded with work (AOR=10.919, 95% CI 1.313-90.819), those whose family members expected them to perform household tasks equivalent to non-working women (AOR=9.369, 95% CI 1.077-81.525), and those experiencing challenges from family, relatives, or neighbors regarding their employment (AOR=8.180, 95% CI 3.663-18.268). Unfavorable working conditions, excessive workload, limited organizational support, and inadequate family support were also associated with depressive symptoms.</div></div><div><h3>Conclusion</h3><div>Poor mental health can adversely affect work productivity, family responsibilities, and social relationships. Strengthening workplace support systems, promoting equitable domestic responsibility-sharing, and formulating targeted policies and programs are essential to improving the mental well-being of working women in Bangladesh.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101062"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147702551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metacognitive functioning in love addiction: An exploratory brief report","authors":"Roberta Gabriella Cavalli,&nbsp;Serena Bruno,&nbsp;Camilla Tacchino,&nbsp;Patrizia Velotti","doi":"10.1016/j.jadr.2026.101029","DOIUrl":"10.1016/j.jadr.2026.101029","url":null,"abstract":"<div><div>Concerning research on behavioral addictions, literature focused on metacognitive beliefs, pointing out a gap in understanding the underlying processes of metacognition. Metacognitive functioning is recognized as a transdiagnostic construct across psychopathological conditions. To explore this aspects, 30 interviews with individual diagnosed with Love Addiction were transcribed and analyzed using the Metacognition Assessment Scale (MAS). Findings indicate that while patients demonstrate a solid grasp of their own mental states, they struggle to comprehend others' minds, both from an egocentric and decentered perspective. Additionally, the most frequently employed coping strategy for managing psychological distress involves the voluntary regulation of mental states, directly modifying maladaptive perceptions. This study serves as an initial step toward a more comprehensive clinical understanding of Love Addiction, identifying both the most impaired and the more functional metacognitive domains.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101029"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to PTSD treatment in veterans with traumatic brain injury: A mixed-methods analysis","authors":"Tamar Rodney,&nbsp;Kara Elizabeth Leonard,&nbsp;Marcus Charles Dyson,&nbsp;Akasi Aryitey,&nbsp;Emma Mangano","doi":"10.1016/j.jadr.2026.101027","DOIUrl":"10.1016/j.jadr.2026.101027","url":null,"abstract":"<div><div>Traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) are prevalent among veterans, often leading to significant functional, social, and occupational impairments, as well as chronic health issues and increased suicide risk. The objective of this study was to evaluate PTSD symptom severity and the time elapsed between diagnosis and treatment-seeking among veterans with TBI. Using online recruitment via social media platforms and veteran databases, 150 veterans participated between January 2021 and July 2022. The study utilized qualitative interviews and an online survey to explore the decision-making process and barriers to seeking PTSD treatment. All data were self-reported. The severity of PTSD symptoms was assessed using the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), with a score above 31 indicating probable PTSD. Findings revealed that 63% of veterans had probable PTSD. Notably, the time taken to seek treatment ranged from 1 to 37 years, with an average delay of 3.57 years. These results highlight the need for improved mental healthcare delivery among veterans and the importance that prolonged treatment-seeking behaviors can have on veterans' PTSD symptoms and ultimately their health.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101027"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the natural landscape of the chronology of major depressive disorder and mania in youth","authors":"Maria Iorini ,&nbsp;Maura DiSalvo ,&nbsp;Gagan Joshi ,&nbsp;Janet Wozniak ,&nbsp;Mai Uchida","doi":"10.1016/j.jadr.2026.101037","DOIUrl":"10.1016/j.jadr.2026.101037","url":null,"abstract":"<div><h3>Introduction</h3><div>Major Depressive Disorder (MDD) and Bipolar Disorder (BPD) are debilitating disorders increasingly prevalent in pediatric populations. MDD and BPD often share depressive symptoms, making them difficult to distinguish. Despite these similarities, treatment courses differ vastly, and incorrect prescriptions can worsen the clinical course. Thus, accurate diagnosis is critical. Further complicating diagnosis is that BPD may initially present with depression, mania, or both. However, there is limited literature examining the course of disorder development. This was a naturalistic cohort study aiming to identify the main patterns of symptoms and relationship to MDD versus BPD development over time.</div></div><div><h3>Methods</h3><div>A cross-sectional assessment of psychiatric interviews (K-SADS-E) was reviewed from 2947 consecutive referrals of patients aged 3 to 17 to a pediatric psychopharmacology program (1991–2008).</div></div><div><h3>Results</h3><div>46% (<em>n</em> = 1357) of the sample met criteria for depression and/or mania. Among them, 60% (<em>n</em> = 818) had only MDD, 7% (<em>n</em> = 101) only mania, and 33% (<em>n</em> = 428) had both. Of the comorbid group, 29% (<em>n</em> = 126) developed depression before mania, 39% (<em>n</em> = 172) developed both concurrently, and 32% (<em>n</em> = 140) had mania before depression. Average age of onset was 5.9 ± 4.4 years for mania and 7.4 ± 4.2 years for depression.</div></div><div><h3>Discussion</h3><div>The results highlight irregularity in the trajectory of depression and mania in youth. Without biomarkers, clinical acumen is necessary to distinguish between the two. Given the high consequences of misdiagnosis, including manic switch, great care must be taken in prescribing. By illustrating the chronology of mood symptoms, we aim to support clinicians in the diagnostic process.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101037"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146190109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Light therapy in seasonal affective disorder: a systematic review and meta-analysis of randomized controlled and crossover trials","authors":"Chiung-Jane Wu ,&nbsp;Doreen Phiri ,&nbsp;Hsiu-Ju Jen ,&nbsp;Anggi Setyowati ,&nbsp;Min-Huey Chung","doi":"10.1016/j.jadr.2025.101021","DOIUrl":"10.1016/j.jadr.2025.101021","url":null,"abstract":"<div><h3>Background</h3><div>The efficacy of light therapy for seasonal affective disorder (SAD) has been supported in several studies. However, the duration of the effectiveness of light therapy at different time points has not been robustly examined.</div></div><div><h3>Objective</h3><div>To investigate the effect of light therapy at different time points of treatment and at post-treatment follow-up among individuals with seasonal affective disorder.</div></div><div><h3>Design</h3><div>A meta-analysis of randomized controlled and crossover trials.</div></div><div><h3>Method</h3><div>Articles were searched in nine electronic databases from inception to April 2025, and 17 eligible randomized controlled trials and crossover trials were included. The risk of bias for each included study was assessed using the criteria in the Cochrane Handbook for Systematic Reviews of Interventions, Version 2.0.</div></div><div><h3>Results</h3><div>Light therapy significantly reduced symptoms of seasonal affective disorder during week 2 (Hedges’ <em>g</em> = -0.62, <em>p</em> &lt; 0.001), while the effect at weeks 1, 3, and 4 were non-significant (<em>g</em> = -0.17, <em>p</em> = 0.066, <em>g</em> = -0.60, <em>p</em> = 0.134, <em>g</em> = -0.15, <em>p</em> = 0.313). These effects correspond to estimated reductions of approximately 0.8, 3.1, 3.05, and 0.8 points, respectively, on the SIGH-SAD scale. At 1-week post-treatment follow-up, the maintenance effects of light therapy were not statistically significant for either 1-week (<em>g</em> = -0.52, <em>p</em> = 0.078) or 2-week (<em>g</em> = -0.36, <em>p</em> = 0.090) treatment durations. Measurement period was the significant moderator at week 2.</div></div><div><h3>Conclusion</h3><div>Light therapy can reduce symptoms of seasonal affective disorder, with a minimum of two weeks recommended to achieve desirable outcomes.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"24 ","pages":"Article 101021"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146190156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}