中华围产医学杂志最新文献

{"title":"Asymptomatic COVID-19 infection in pregnant woman in the third trimester: a case report/ 中华围产医学杂志","authors":"L. Yao, Jing Wang, Jingjing Zhao, Jing Cui, Zhihang Hu","doi":"10.3760/CMA.J.CN113903-20200221-00143","DOIUrl":"https://doi.org/10.3760/CMA.J.CN113903-20200221-00143","url":null,"abstract":"We report a case of asymptomatic COVID-19 infection in a pregnant woman in the third trimester with good maternal and infant outcomes. The patient was admitted to the Second People's Hospital of Hefei on February 11, 2020, because of a \"positive novel coronavirus nucleic acid test result for one day\" at 38 weeks of gestation. No abnormality was observed during her previous regular prenatal examinations. A throat swab sample was obtained from the patient four days before admission due to the diagnosis of COVID-19 infection in her husband and sister on the 14th and 7th day before her admission, and the new coronavirus nucleic acid test showed positive. The patient reported no discomfort before admission. Chest CT on the 3rd after admission showed a small amount of bilateral pleural effusion. Irregular contractions occurred three days after admission and labor was considered to be imminent. An emergency cesarean section was performed and the patient delivered a live baby girl. No tests were performed on amniotic fluid, cord blood or placenta for new coronavirus nuclei acid. The patient was isolated from the infant without breastfeeding after surgery. All medical staff involved in the cesarean section were isolated after surgery. Neonatal peripheral blood and nasopharyngeal swabs were collected for the new coronavirus nucleic acid tests on the day of birth and one day of age respectively, and nasopharyngeal swabs and anal suabs were taken at nine days after birth. All test results were negative. The patient recovered well after surgery with stable vital signs. Chest CT on the 8th after operation showed a small amount of bilateral pleural effusion, while the new coronavirus nucleic acid test results of the pharyngeal swabs were positive on the 11th and 12th day after operation. The throat swabs of all medical staff involved in the operation were negative 14 days after the operation. The mother and baby were discharged 14 days after the Cesarean section.","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"229-231"},"PeriodicalIF":0.0,"publicationDate":"2020-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42997780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term effects of intrauterine exposure to metformin on offspring","authors":"Heng-jun Liu, Chang Chen, Fei Li, Lin Zhang, Jun Zhang","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.010","url":null,"abstract":"As an oral antidiabetic drugs, metformin has been widely used to treat various diseases such as gestational diabetes mellitus, polycystic ovary syndrome and obesity in pregnant women. Current literature suggests that intrauterine metformin exposure has no significant impact on perinatal outcomes of the offspring, such as neonatal hypoglycemia, neonatal respiratory distress syndrome, premature delivery and others. However, considering the possible transfer of metformin across the placental barrier, intrauterine metformin exposure may potentially influence the development of placenta and the fetus, cell metabolism, and hormone levels. According to the \"Developmental Origins of Health and Diseases\"theory, the long-term effect of intrauterine metformin exposure on the growth, metabolism, reproductive function and neuropsychological development of offspring reviewed here still need continuous attention. \u0000 \u0000Key words: \u0000Metformin; Prenatal exposure delayed effects; Growth and development; Child development","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"126-130"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49226999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress in use of metformin in pregnancy with diabetes","authors":"Ye Feng, Huixia Yang","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.009","url":null,"abstract":"The efficacy as well as short- and long-term safety of metformin in women with gestational diabetes mellitus have been constantly confirmed in recent years. Metformin could decrease the weight gain during pregnancy and the incidence of hypoglycemia compared with insulin, without increasing the incidence of adverse pregnant outcomes. Moreover, no significant adverse outcome has been found in the offspring of women treated with metformin in pregnancy. This article reviews the evidence for efficacy and safety of using metformin during pregnancy, summarizes the latest guidelines and recommendations, and describes the specific medication regimen. \u0000 \u0000Key words: \u0000Metformin; Diabetes, gestational; Validation studies; Clinical protocols","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"121-125"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41721561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin resistance and pregnancy outcomes in gestational diabetes mellitus gravida complicated by chronic hypertension","authors":"J. Juan, Yiying Sun, C. Ye, Huixia Yang","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.004","url":null,"abstract":"Objective \u0000To analyze insulin resistance (IR) level and pregnancy outcomes in women with gestational diabetes mellitus (GDM) complicated by chronic hypertension (CHT). \u0000 \u0000 \u0000Methods \u0000This is a retrospective case-control study involving 2 457 singleton pregnant women complicated by GDM who received regular prenatal examinations and participated in the one-day-care clinic of GDM in Peking University First Hospital from January 1, 2014 to December 31, 2016. Clinical data were collected and homeostasis model assessment insulin resistance (HOMA-IR) was calculated. All subjects were divided into two groups: GDM with CHT group (CHT group, n=47) and GDM without CHT group (non-CHT group, n=2 410). Based on their pre-pregnancy body mass index (BMI), they were also grouped into normal pre-pregnancy BMI group (n=1 590) and overweight and obese group (n=863). Two-sample independent t test and Chi-square test were used to compared the age, HOMA-IR, pre-pregnancy BMI, weight gain during pregnancy and glucose levels between groups, and logistic regression model was used to analyze the effects of HOMA-IR on pregnancy outcomes. \u0000 \u0000 \u0000Results \u0000HOMA-IR (3.5±1.8 vs 2.6±1.5, t=-3.290), fasting plasma glucose [(5.4±0.5) vs (5.2±0.5) mmol/L, t=-3.005], pre-pregnancy BMI [(26.7±4.7) vs (23.3±3.4) kg/m2, t=-4.842] and the incidence of preeclampsia [14.9% (7/47) vs 2.5% (61/2 410), χ2=21.790] were significantly higher in GDM women with CHT than those without (all P 0.05). For pregnant women with normal pre-pregnancy BMI, HOMA-IR (3.0±1.5 vs 2.3±1.2, t=-2.217), fasting plasma glucose [(5.4±0.5) vs (5.1±0.5) mmol/L, t=-2.299] and the incidence of preeclampsia [2/14 vs 1.6% (26/1 576), χ2=6.545] were higher in the CHT group than the non-CHT group (all P 0.05). After adjusting for age, fasting plasma glucose, pre-pregnancy BMI and weight gain during pregnancy, the elevated HOMA-IR level increased the risk of preterm birth (OR=1.223, 95%CI: 1.093-1.369, P<0.001) in GDM women without CHT. \u0000 \u0000 \u0000Conclusions \u0000GDM gravida complicated by CHT have severe insulin resistance and a higher incidence of preeclampsia, but the risk of other pregnancy outcomes are not increased. \u0000 \u0000 \u0000Key words: \u0000Diabetes, gestational; Hypertension; Insulin resistance; Pregnancy outcome","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"91-97"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42228715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different characteristics of gut microbiota before and after management of women with gestational diabetes mellitus and the association with blood glucose level","authors":"Yu Liu, Jing-mei Ma, S. Qin, B. Zhu, Fei Liu, Huixia Yang","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.005","url":null,"abstract":"Objective \u0000To investigate the gut microbial profiles of gestational mellitus diabetes (GDM) patients before and after treatment, and the relationship between gut microbiota and blood glucose level measured in 75 g oral glucose tolerance test (OGTT). \u0000 \u0000 \u0000Methods \u0000A prospective cohort-based nested case-control study was conducted in Peking University First Hospital from October 2016 to December 2017. Forty-five pregnancies at 24-28 gestational weeks with GDM (GDM group) and 45 healthy gravidas (control group) matched for age and pre-pregnancy body mass index (BMI) were involved. Stool samples of all participants were collected before (24-28 gestational weeks) and after (36-40 gestational weeks) treatment. The V3-V4 region of the 16S rRNA gene was sequenced on the Illumina Hiseq 2500 platform, and the results were analyzed. QIIME software was used for bioinformatics analysis. Student's t-test, Mann-Whitney U test, and Chi-square test were used for statistical analysis. \u0000 \u0000 \u0000Results \u0000(1) Before treatment, the Alpha diversity of the GDM group was significantly reduced compared with that of the control group (Chao1 index: 443.9±72.9 vs 474.0±63.3, t=2.104, P<0.05; Shannon index: 5.6±0.5 vs 6.0±0.5, t=2.002, P<0.05), and a significant difference in Beta diversity was also observed between the two groups (R2=0.04, P<0.05). However, a significant difference was shown in neither Alpha nor Beta diversity between the two groups after the treatment. (2) Before treatment, the relative abundances of Blautia and Faecalibacterium of the GDM group were significantly higher than those of the control group [M (P25-P75): 0.016 (0.009-0.022) vs 0.011 (0.007-0.016), U=782.000; 0.114 (0.076-0.141) vs 0.091 (0.061-0.126), U=752.000; both P<0.05], but the relative abundances of Akkermansia, Odoribacter and Butyricimonas were significantly lower [0.001 (0.000-0.002) vs 0.001 (0.000-0.005), U=745.000; 0.001 (0.000-0.004) vs 0.004 (0.001-0.006), U=766.500; 0.001 (0.000-0.003) vs 0.003 (0.001-0.005), U=710.000; all P<0.05]. (3) A negative relationship was found between the fasting glucose level of OGTT and the relative abundances of Akkermansia, Odoribacter and Butyricimonas (r=-0.325, -0.273 and -0.284; all P<0.05), and between the one-hour-OGTT glucose level and the relative abundances of Akkermansia and Butyricimonas (r=-0.285 and -0.265, both P<0.05). The two-hour-OGTT glucose level was positively related to the relative abundance of Faecalibacterium (r=0.278, P<0.05), but negatively related to the relative abundance of Akkermansia (r=-0.245, P<0.05). The area under the OGTT time-glucose curve was negatively related to the relative abundances of Akkermansia and Butyricimonas (r=-0.321 and -0.264, both P<0.05). \u0000 \u0000 \u0000Conclusions \u0000There are significant differences in gut microbial composition and structure between GDM and healthy pregnant women, which are significantly associated with OGTT blood glucose level. Euglycemia achieved after GDM management could improve gut micro","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"98-104"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44734499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal obesity and gestational diabetes mellitus","authors":"Zhimin Song, Yan-hi Cheng, Qingying Zhang, Haidong Cheng","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.011","url":null,"abstract":"Gestational diabetes mellitus (GDM) refers to the carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. In recent years, the growing prevalence of obesity and GDM has been of long-standing interest. Maternal obesity is an independent risk factor of GDM, which can lead to adverse pregnancy outcomes. This review describes the relationship between maternal obesity and GDM from the aspects of the evaluation index and the management of obesity during pregnancy. \u0000 \u0000Key words: \u0000Diabetes, gestational; Obesity; Body mass index","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47029474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in human milk stem cells","authors":"Shujuan Li, Yi Yang, Yun Cao","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.012","url":null,"abstract":"Recent studies have revealed that human milk harbors stem cells at various stages of differentiation, including pluripotent stem cells, hematopoietic stem cells and mesenchymal stem cells. The stem cellular components of human milk with high interindividual variability are affected by gestational age and lactation stages. The maternal stem cells which pass to the infant through human milk could help boost offspring growth and development. Human milk stem cell with multi-directional differentiation potential may be a new source of stem cell replacement therapy in the future. We hereby review the latest progress in human milk stem cells from these aspects. \u0000 \u0000Key words: \u0000Milk, human; Stem cells; Child development","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"135-138"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48509217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A healthy neonate born at the third pregnancy of a woman with ornithine carbamoyltransferase deficiency under multidisciplinary management","authors":"Yan Zeng, Yuelin Wu, Huaxiang Shen, Mengnan Yang, Shengyi Gu, Zhengqian Mou, Xiaolin Hua","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.007","url":null,"abstract":"We reported a women with ornithine carbamoyltransferase deficiency who delivered a healthy boy after two pregnancies with adverse outcome with the help of a multidiscipline team. The woman was admitted to Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine with an acute prenatal hyperammonemic episode at 28 gestational weeks of her first pregnancy in 2013 and was diagnosed with ornithine transcarbamylase deficiency. Her hyperammonemic complications were controlled under a well-planned multidisciplinary management including a low-protein diet and appropriate medications assisting nitrogen removal. A boy was delivered by cesarean section at 32 weeks of gestation but died three days later. Mutation analysis revealed a hemizygous c.583G>A (G195R) mutation in the neonatal ornithine carbamyltransferase gene and his mother was a heterozygous carrier with the same mutation. Two years later in 2015, the patient was pregnant spontaneously. However, she received an induced abortion at 21 weeks of gestation because amniocentesis and DNA analysis showed that the male fetus had the same ornithine transcarbamylase gene mutation. The index pregnancy was assisted by in vitro fertilization-embryo transfer and preimplantation genetic diagnosis in 2017 and the woman delivered a healthy boy with the management of a multidisciplinary team. \u0000 \u0000Key words: \u0000Ornithine carbamoyltransferase deficiency disease; Gravidity; Peripartum period; Patient care management","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"111-113"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49049657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of early skin-to-skin contact after cesarean section on maternal psychological status and exclusive breastfeeding rate: a prospective randomized controlled study","authors":"Luan-ying Tian, H. Li, Zhen Wang","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.006","url":null,"abstract":"Objective \u0000To investigate the influence of early skin-to-skin contact (SSC) after cesarean section on maternal psychological status and the rate of exclusive breastfeeding. \u0000 \u0000 \u0000Methods \u0000This was a prospective randomized controlled study enrolling 221 singleton pregnant women who underwent elected caesarean section at term in Shenzhen Nanshan Maternity and Child Healthcare Hospital from August 1 to December 31, 2017. They were randomly divided into SSC group and control group. In the SSC group, naked infants were placed on the mothers' chests within 1 h after delivery for 1-2 h, while those in the control group received standard care. Clinical outcomes were compared between two groups, including the rate of exclusive breastfeeding and score of Breastfeeding Self-Efficacy Scale (BSES) and Edinburgh Postnatal Depression Scale (EPDS) at 72 h and 42 d after delivery, scores of Breastfeeding Assessment Tool (BAT) for the first breastfeeding, time to lactogenesis and successful rate of first breastfeeding. Two-independent sample t test, Chi-square test and binary logistic regression analysis were used as statistical methods. \u0000 \u0000 \u0000Results \u0000Eventually, 210 puerperae were analyzed with 105 in each group. Twenty in the SSC group and 17 in the control group were lost to follow-up 42 d after delivery. The successful rate of first breastfeeding [77.1% (81/105) vs 59.1% (62/105), χ2=7.913, P=0.005], BAT scores (9.5±1.7 vs 8.6±1.4, t=4.115, P<0.001), the rate of lactation initiation ≤24 h after birth [41.0% (43/105) vs 12.4% (13/105), χ2=23.205, P<0.001], and exclusive breastfeeding rates [36.2% (38/105) vs 22.9% (24/105), χ2=4.486, P=0.034; 76.5% (65/85) vs 60.2% (63/88), χ2=5.261, P =0.022] and BESE scores (117.5±12.0 vs 111.8±22.3, t=2.100, P=0.037; 124.3±11.6 vs 113.1±19.0, t=4.710, P<0.001) at 72 h and 42 d after delivery were all higher in the SSC group than those in the control group. However, no statistically significant difference in EPDS scores was observed between the two groups at either 72 h or 42 d after delivery (5.4±3.5 vs 5.9±4.0, t=0.937, P=0.350; 7.0±3.7 vs 8.1±4.0, t=0.905, P=0.058). Binary logistic regression analysis showed early SSC was a protective factor for successful exclusive breastfeeding 42 d after delivery (OR=2.359, 95%CI: 1.173-4.743, P=0.016). \u0000 \u0000 \u0000Conclusions \u0000Early SSC after caesarean should be recommended as a usual clinical practice because it can improve maternal confidence on breastfeeding, shorten the time to lactogenesis and increase the successful rate of first breastfeeding and exclusive breastfeeding rate during puerperium. \u0000 \u0000 \u0000Key words: \u0000Breast feeding; Postpartum period; Self efficacy; Self-assessment; Assertiveness; Randomized controlled trial","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"105-110"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46518336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal novel coronavirus infection: a case report","authors":"Siying Zhuang, Juanjuan Guo, Yuming Cao, Huijun Chen, Dan Xu, J. Li, Yuan-zhen Zhang","doi":"10.3760/CMA.J.ISSN.1007-9408.2020.02.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2020.02.003","url":null,"abstract":"We hereby reported the diagnosis, treatment process and perinatal outcome of a patient with novel coronavirus infection in perinatal period. The pregnant woman delivered a boy by cesarean section at 37+2 gestational weeks due to severe liver dysfunction. She subsequently had a high fever 2 days later, and novel coronavirus infection was confirmed by nucleic acid test in a throat swab. After a 12-day isolation and support treatment, her two consecutive throat swab results for novel coronavirus turned negative and she was discharged. The novel coronavirus was tested in the patient's blood, urine, breast milk as well as the neonatal throat swab, and the results were all negative. The neonate had an elevated myocardial enzyme, but was otherwise well and was discharged after 14-day isolation with normal myocardial enzyme. \u0000 \u0000Key words: \u0000Novel coronavirus; Pregnancy; Infant, newborn","PeriodicalId":52320,"journal":{"name":"Chinese Journal of Perinatal Medicine","volume":"23 1","pages":"85-90"},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49309351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}