二甲双胍在妊娠糖尿病患者中的应用进展

Q4 Medicine

中华围产医学杂志 Pub Date : 2020-02-16 DOI:10.3760/CMA.J.ISSN.1007-9408.2020.02.009

Ye Feng, Huixia Yang

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引用次数: 0

摘要

近年来，二甲双胍治疗妊娠期糖尿病的疗效和短期、长期安全性不断得到证实。与胰岛素相比，二甲双胍可以降低妊娠期体重增加和低血糖的发生率，而不会增加不良妊娠结局的发生率。此外，在怀孕期间接受二甲双胍治疗的妇女的后代中没有发现明显的不良后果。本文综述了妊娠期间使用二甲双胍的有效性和安全性的证据，总结了最新的指南和建议，并介绍了具体的用药方案。关键词:二甲双胍;糖尿病,妊娠期;验证研究;临床协议

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Progress in use of metformin in pregnancy with diabetes

The efficacy as well as short- and long-term safety of metformin in women with gestational diabetes mellitus have been constantly confirmed in recent years. Metformin could decrease the weight gain during pregnancy and the incidence of hypoglycemia compared with insulin, without increasing the incidence of adverse pregnant outcomes. Moreover, no significant adverse outcome has been found in the offspring of women treated with metformin in pregnancy. This article reviews the evidence for efficacy and safety of using metformin during pregnancy, summarizes the latest guidelines and recommendations, and describes the specific medication regimen. Key words: Metformin; Diabetes, gestational; Validation studies; Clinical protocols

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来源期刊

中华围产医学杂志 Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

4446

期刊介绍： Chinese Journal of Perinatal Medicine was founded in May 1998. It is one of the journals of the Chinese Medical Association, which is supervised by the China Association for Science and Technology, sponsored by the Chinese Medical Association, and hosted by Peking University First Hospital. Perinatal medicine is a new discipline jointly studied by obstetrics and neonatology. The purpose of this journal is to "prenatal and postnatal care, improve the quality of the newborn population, and ensure the safety and health of mothers and infants". It reflects the new theories, new technologies, and new progress in perinatal medicine in related disciplines such as basic, clinical and preventive medicine, genetics, and sociology. It aims to provide a window and platform for academic exchanges, information transmission, and understanding of the development trends of domestic and foreign perinatal medicine for the majority of perinatal medicine workers in my country.