{"title":"Effect of Perioperative Sucralfate Administration on Pain Control After Tonsillectomy: A Systemic Review and Meta-Analysis.","authors":"Do Hyun Kim, David W Jang, Se Hwan Hwang","doi":"10.1177/00034894261449776","DOIUrl":"10.1177/00034894261449776","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the efficacy of perioperative intraoral sucralfate in reducing postoperative pain following tonsillectomy through a systematic review and meta-analysis.</p><p><strong>Methods: </strong>A comprehensive search of PubMed, SCOPUS, Embase, Web of Science, and Cochrane up to September 2025 identified 13 studies comparing perioperative intraoral sucralfate with placebo or no treatment. Outcomes included throat pain, otalgia, swallowing pain, analgesic consumption, and perioperative morbidities.</p><p><strong>Results: </strong>Sucralfate increased the proportion of patients reporting no or mild throat pain and otalgia, improved mucosal healing at 5 to 7 days, and reduced throat pain, swallowing pain, otalgia, analgesic use, and time to resume >50% of a regular diet. No significant differences were observed in postoperative bleeding or nausea/vomiting.</p><p><strong>Conclusion: </strong>Perioperative intraoral sucralfate may be an effective adjuvant therapy that improves postoperative pain control, enhances wound healing, reduces analgesic requirements, and facilitates earlier dietary resumption after tonsillectomy.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"737-745"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Trace T Palmer, Cindy M Moore, Kelsey L Bounds-Wood, William Bryant, Alexandra Rose, Oishika Paul, Christopher Spankovich, Gina D Jefferson
{"title":"Comparison of Adult Tracheostomy Outcomes Before and After Implementation of a Dedicated Tracheostomy Team.","authors":"Trace T Palmer, Cindy M Moore, Kelsey L Bounds-Wood, William Bryant, Alexandra Rose, Oishika Paul, Christopher Spankovich, Gina D Jefferson","doi":"10.1177/00034894261450132","DOIUrl":"10.1177/00034894261450132","url":null,"abstract":"<p><strong>Objective: </strong>(A) Determine patient and institutional factors associated with increased length of stay (LOS) and complications of tracheostomy, (B) Develop data-driven quality improvement in tracheostomy care.</p><p><strong>Design: </strong>Mixed methods protocol used cross-sectional survey assessing institutional trends in tracheostomy-specific care. Retrospective chart review compared tracheostomy patient outcomes prior to and during implementation of a multidisciplinary tracheostomy care team and standardized guidelines.</p><p><strong>Participants: </strong>Patients undergoing tracheostomy from January 2019 to December 2021 at a tertiary hospital.</p><p><strong>Methods: </strong>Patient factors, procedure type and indication, tracheostomy tube size, management timeline, insurance, and disease severity using Acute Physiology and Chronic Health Evaluation II (APACHE II) score were analyzed for associations with LOS and adverse events. Multivariate analyses controlled for APACHE II score and payer source. LOS and complications were compared between patients before and during implementation of multidisciplinary tracheostomy care team and standardized guidelines.</p><p><strong>Results: </strong>Three-hundred and eighteen patients met criteria with a 21.7% complication rate, average LOS of 24 days (SD = 28.523), and median LOS post-tracheostomy of 14 days (IQR 7, 29). Departments without standardized protocols had greater LOS (<i>F</i>[1,316] = 28.706, <i>P</i> < .001]) and complication odds (OR = 2.92, <i>P</i> = .015, 95% CI[1.231, 6.930]). Larger tracheostomy tube size was linked to increased LOS (β = .253, <i>t</i>(314) = 4.741, <i>P</i> < .001, 95% CI[4.137, 10.081]). Delays from ventilation discontinuation to cuffless tube exchange and decannulation correlated with increased LOS (β = .406, <i>t</i>(184) = 6.321, <i>P</i> < .001, 95% CI[.928, 1.771]); (β = .554, <i>t</i>(129) = 7.625, <i>P</i> < .001, 95% CI[1.008, 1.715]). When focusing on a single department, comparing 2019 patients to 2021 patients (pre- and post-guideline and care team), overall, LOS decreased from 33.08 to 30.83 days (<i>P</i> = .586). When excluding patients discharged on a ventilator, the 2019 group had average LOS of 37.938 days versus 33.41 days in 2021 (<i>P</i> = .344).</p><p><strong>Conclusions: </strong>Standardized tracheostomy care guidelines and multidisciplinary care teams are critical to improving institutional outcomes. Data-driven approaches to quality improvement ensure efficient and targeted methods to improving patient care.</p><p><strong>Level of evidence: </strong>4.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"752-759"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147944744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brady J Anderson, Scott M Graham, Brian T Andrews, Joseph D Camargo, Douglas E Kendrick
{"title":"Response to Pitak-Arnnop \"Letter to the Editor\".","authors":"Brady J Anderson, Scott M Graham, Brian T Andrews, Joseph D Camargo, Douglas E Kendrick","doi":"10.1177/00034894261449750","DOIUrl":"10.1177/00034894261449750","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"813-814"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147937092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katelyn S Rourk, Cecelia M Hidalgo, Anne K Shurtz, Kendall K Tasche, Daniel L Price, Kathryn M Van Abel, Linda X Yin, Eric J Moore
{"title":"Long-Term Survey to Assess Recurrence and Complications of Surgically Treated Pleomorphic Adenoma.","authors":"Katelyn S Rourk, Cecelia M Hidalgo, Anne K Shurtz, Kendall K Tasche, Daniel L Price, Kathryn M Van Abel, Linda X Yin, Eric J Moore","doi":"10.1177/00034894261453714","DOIUrl":"10.1177/00034894261453714","url":null,"abstract":"<p><strong>Objective(s): </strong>To (1) report on the long-term recurrence rate of surgically managed pleomorphic adenoma (PA) and (2) assess long-term surgical outcomes after parotidectomyMethods:Cross-sectional survey of all patients with a pathologic diagnosis of PA who underwent surgical management in a tertiary care center from 01/1997 to 12/2023 and had access to an electronic patient portal. Surveys were delivered via electronic patient portal or phone call with 6 questions to assess recurrence and long-term surgical outcomes. Time to first recurrence and recurrence free survival were analyzed using a Kaplan-Meier curve.</p><p><strong>Results: </strong>Seven hundred-forty-five patients met inclusion criteria and received the survey, with a 56% response rate (n = 420). The clinical median follow-up length was 51 days, which extended to a median length of 6.2 years following the survey. The median change in follow-up length was 5.37 years (<i>P</i> < .001). The recurrence rate was 1% at 5 years, with a median time to first recurrence of 7.54 years. 13% and 9% of responders reported facial asymmetry and incisional cosmetic concerns, respectively. 33% of patients reported experiencing Frey syndrome, which increased from 5.2% of survey responders with documented Frey syndrome at their original post-operative assessment.</p><p><strong>Conclusion: </strong>Long-term assessment of PA outcomes confirms low recurrence rates, suggesting regular surveillance of recurrence is likely unnecessary. Complaints of Frey syndrome increased in frequency with longer term follow-up, which should be considered during patient counseling.</p><p><strong>Level of evidence: </strong>3.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"780-788"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147978483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor Regarding \"The Maxillary Lid Approach to Intra-Antral Pathology\".","authors":"Poramate Pitak-Arnnop","doi":"10.1177/00034894261449769","DOIUrl":"10.1177/00034894261449769","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"810-812"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serhat Tonç, Özge Çağlar Çil, Mahmut Serdar Sofu, Dilan Akarsu, Oğuz Güçlü
{"title":"Effects of Crocin on Wound Healing and Fibrosis in Vocal Cord Injury: An Experimental Study.","authors":"Serhat Tonç, Özge Çağlar Çil, Mahmut Serdar Sofu, Dilan Akarsu, Oğuz Güçlü","doi":"10.1177/00034894261451418","DOIUrl":"10.1177/00034894261451418","url":null,"abstract":"<p><strong>Objective: </strong>This experimental study aimed to evaluate the effects of crocin on wound healing and fibrosis in vocal fold injury.</p><p><strong>Materials and methods: </strong>Thirty-six male Wistar Albino rats were randomly divided into 3 groups: a sham group, a local crocin treatment group, and a systemic crocin treatment group. In the study, all rats underwent injury to their right vocal folds. Six rats from each group were randomly sacrificed on the 5th and 30th days after surgery. Tissue samples were evaluated for lamina propria thickness, inflammation severity, epithelial regeneration, edema, hyaluronic acid, collagen, elastin, and the cytokines TGF-β1, FGF2, and HGF.</p><p><strong>Results: </strong>In the early phase, less inflammation, more epithelial regeneration, and lamina propria were observed in the systemic treatment group compared to the sham group. In the late phase, Compared to the sham group, both the systemic and local treatment groups showed higher values in lamina propria thickness, elastin, and HGF measurements, while collagen levels were significantly decreased. Furthermore, in the systemic group, TGF-β1 decreased in the late period, while hyaluronic acid and FGF2 levels remained high. When the groups were evaluated within themselves, inflammation and edema were observed to decrease more significantly in the late period in all groups. Hyaluronic acid decreased significantly in the sham and local treatment groups, while this decrease was limited in the systemic treatment group. Lamina propria thickness increased significantly in the treatment groups on day 30 compared to day 5.</p><p><strong>Conclusion: </strong>Crocin treatment applied using different methods has shown positive effects on various parameters, wound healing, and fibrosis reduction in the early and late periods after vocal fold injury. However, more extensive preclinical and clinical studies are needed to determine the efficacy and applicability of this treatment.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"789-795"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147937029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clifford Jiajun He, Douglas M Bennion, Abhishek Bhatt, Michael G Brandel, Brian Hirshman, Joshua Lee, Marc S Schwartz, Rick A Friedman
{"title":"Prophylactic Nimodipine for Hearing Preservation in Vestibular Schwannoma: A Retrospective Cohort Study.","authors":"Clifford Jiajun He, Douglas M Bennion, Abhishek Bhatt, Michael G Brandel, Brian Hirshman, Joshua Lee, Marc S Schwartz, Rick A Friedman","doi":"10.1177/00034894261491080","DOIUrl":"https://doi.org/10.1177/00034894261491080","url":null,"abstract":"<p><strong>Background: </strong>Vestibular schwannoma surgery poses a significant challenge for hearing and facial function preservation. Prophylactic nimodipine has been studied as a pharmacologic strategy to protect cranial nerve function after hearing preservation surgery, but it has not been thoroughly evaluated. This study aimed to assess the role of prophylactic nimodipine in promoting hearing and facial function following vestibular schwannoma surgery and to evaluate the dose-response relationship between nimodipine administration and patient outcomes.</p><p><strong>Methods: </strong>We conducted a retrospective analysis on a cohort of vestibular schwannoma patients who underwent hearing preservation surgery at a tertiary care hospital between November 2017 and December 2024. Hearing outcomes were assessed using word recognition scores and pure tone audiometry, and facial function outcomes were assessed with House-Brackmann Score. Regression analyses were performed to determine the impact of nimodipine on hearing preservation and to evaluate dose-response relationships.</p><p><strong>Results: </strong>The study included 58 control patients and 340 nimodipine-treated patients. Nimodipine treatment significantly improved cranial nerve outcomes. Compared to controls, nimodipine-treated patients had 2.0 times greater odds of preserving word recognition score (OR: 1.92, 95% CI: 1.08-3.44, <i>P</i> = .027), 1.5 times greater odds of preserving pure tone average (OR: 1.49, 95% CI: 0.84-2.66, <i>P</i> = .17), and 2.0 times greater odds of preserving facial nerve function (OR: 2.02, 95% CI: 1.10-3.73, <i>P</i> = .024). Dose-response analyses revealed that each additional nimodipine dose was associated with a 2.3% improvement in word recognition (<i>P</i> < .001), 1.7% improvement in pure tone average preservation (<i>P</i> < .001), and 1.1% improvement in facial nerve preservation (<i>P</i> = .049).</p><p><strong>Conclusion: </strong>Prophylactic nimodipine demonstrates potential efficacy in enhancing post-operative cranial nerve function after hearing preservation vestibular schwannoma surgery. These findings support further investigation through prospective studies to confirm nimodipine's clinical utility.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894261491080"},"PeriodicalIF":0.0,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149077461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alisha R Pershad, Sophia Song, Esther Lee, Adam Thompson-Harvey, Neelima Tummala, Punam Thakkar
{"title":"How Medical School Experiences Bias Specialty Selection: Perspectives From Current U.S. Otolaryngology Residents.","authors":"Alisha R Pershad, Sophia Song, Esther Lee, Adam Thompson-Harvey, Neelima Tummala, Punam Thakkar","doi":"10.1177/00034894261485442","DOIUrl":"https://doi.org/10.1177/00034894261485442","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined the medical school experiences of current U.S. otolaryngology residents to better understand gender biases that may persist within the specialty and to inform strategies that could improve workforce excellence.</p><p><strong>Methods: </strong>A voluntary, IRB-approved survey was distributed to U.S. otolaryngology residency program directors and coordinators for distribution to their residents. Gender-stratified analyses were performed using Chi-squared tests, Mann-Whitney tests, and thematic analysis. A <i>P</i>-value < .05 was considered statistically significant.</p><p><strong>Results: </strong>Of 137 complete surveys, 58% of respondents identified as female (mean age 29.7 ± 2.8 years). Factors that deterred female respondents from pursuing otolaryngology included a perceived requirement of high USMLE board scores (<i>P</i> < .05), concerns about racial, ethnic, gender, and sexual diversity (<i>P</i> < .05), and concerns about time limitations for raising a family (<i>P</i> < .0005). Female respondents were significantly more likely to have witnessed or experienced gender discrimination (<i>P</i> < .05) and received negative comments about their clinical abilities (<i>P</i> < .0005) compared to their male counterparts. Having a gender-concordant mentor significantly influenced career choice among female respondents (<i>P</i> < .0005).</p><p><strong>Conclusions: </strong>Persistent gender disparities continue to shape otolaryngology residents' experiences and perceptions, from mentorship access to perceptions of bias. Key targets for intervention include gender-concordant mentorship, early medical school exposure, and addressing inherent bias through educational and department-wide initiatives. Meaningful progress requires collective institutional commitment to structural and cultural change to ensure a more supportive environment for all trainees.</p><p><strong>Level of evidence: </strong>4.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894261485442"},"PeriodicalIF":0.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149019546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belgin Tutar, Güler Berkiten, Fatma Gülüm Bayraktar, Hasan Sami Bircan, Cem Çelik, Ali Ozan Yazıcı, Seher Haksever Horat, Yavuz Uyar
{"title":"Association Between Nasal Septal Deviation Types and Eustachian Tube Function: A Prospective Observational Study.","authors":"Belgin Tutar, Güler Berkiten, Fatma Gülüm Bayraktar, Hasan Sami Bircan, Cem Çelik, Ali Ozan Yazıcı, Seher Haksever Horat, Yavuz Uyar","doi":"10.1177/00034894261489726","DOIUrl":"https://doi.org/10.1177/00034894261489726","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to objectively and subjectively evaluate the effect of nasal septal deviation (NSD) types, classified according to the Baumann system, on Eustachian tube function.</p><p><strong>Methods: </strong>A total of 107 NSD patients (78 males, 29 females; mean age: 35.39 ± 9.55 years) were included. NSD was categorized into 6 types based on the Baumann classification. All patients completed the NOSE (Nasal Obstruction Symptom Evaluation) scale and ETDQ-7 (Eustachian Tube Dysfunction Questionnaire). Eustachian tube function was evaluated using the ETF-1 (Eustachian Tube Function-1) test, and correlations with NSD types were evaluated.</p><p><strong>Results: </strong>Advanced deviation types (Types 5 and 6) were associated with higher NOSE and ETDQ-7 scores and significantly reduced tympanometric pressure responses during both Toynbee and Valsalva maneuvers. Type 6 exhibited the highest ETDQ-7 scores and the lowest Pmax-Pmin values.</p><p><strong>Conclusion: </strong>Advanced nasal septal deviation was associated with worse subjective and objective measures of Eustachian tube function. These findings may be relevant during preoperative assessment of patients with advanced septal deviation.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894261489726"},"PeriodicalIF":0.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Clinical and Voice Outcome Differences in Vocal Cord Cysts With and Without Sulcus Vocalis\".","authors":"Ahmet Ufuk Kılıçtaş","doi":"10.1177/00034894261489727","DOIUrl":"https://doi.org/10.1177/00034894261489727","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894261489727"},"PeriodicalIF":0.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}