The Annals of otology, rhinology, and laryngology最新文献

{"title":"Efficacy of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis.","authors":"Yeon Hee Im, Gulnaz Stybayeva, Se Hwan Hwang","doi":"10.1177/00034894251349397","DOIUrl":"https://doi.org/10.1177/00034894251349397","url":null,"abstract":"<p><strong>Objectives: </strong>Novel biomechanics of the exhalation delivery system can deliver fluticasone (EDS-FLU; XHANCE) to sinonasal areas above the inferior turbinate, especially sinus drainage pathways not reached by standard nasal sprays. This study aimed to evaluate the effectiveness of EDS-FLU in treating chronic rhinosinusitis (CRS).</p><p><strong>Methods: </strong>Studies were retrieved from PubMed, SCOPUS, Embase, Web of Science, and Cochrane databases up to April 2024. We analyzed 5 studies that compared EDS-FLU with a control group (exhalation delivery system with placebo) on various outcomes, including the 22-item Sinonasal Outcome Test (SNOT-22), nasal symptom scores (congestion, facial pain, olfactory dysfunction, and rhinorrhea), nasal polyp scores, surgical indication rate, and the incidence of adverse effects.</p><p><strong>Results: </strong>Five studies with 2129 patients were included. EDS-FLU significantly improved SNOT-22 score (-20.9657 [-23.5639; -18.3674]) and the polyp score (-1.5099 [-1.7810; -1.2388]) after 6 months. The incidence of epistaxis was significantly higher in the treatment group compared to the control group (OR = 5.7954 [2.1004; 15.9909]). Effects of EDS-FLU on polyp score (-0.6497 [-0.8186; -0.4807]), responder rate (OR = 2.1755 [1.2784; 3.7020]), complete responder rate (OR = 2.0423 [1.0109; 4.1262]), surgical indication rate (OR = 0.7313 [0.5459; 0.9797]), and SNOT-22 score (-6.1513 [-11.3054; -0.9972]) were significantly higher in the treatment group than in the control group.</p><p><strong>Conclusions: </strong>This study demonstrated that EDS-FLU (372 µg twice daily) produced statistically significant improvements compared to EDS-placebo in multiple subjective and objective outcomes, although some adverse effects, such as epistaxis, may occur.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251349397"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Spirituality on Severity, Quality of Life, and Mental Health of Tinnitus Patients.","authors":"Ludimila de Oliveira Cardoso Ouverney, Giancarlo Lucchetti, Caroline Hansen da Silva, Julia Berzoini Albuquerque, Oscarina da Silva Ezequiel, Alessandra Lamas Granero Lucchetti","doi":"10.1177/00034894251349411","DOIUrl":"https://doi.org/10.1177/00034894251349411","url":null,"abstract":"<p><strong>Objective: </strong>Despite the growing evidence on the role of spiritual and religious beliefs on physical and mental health outcomes, this remains inadequately explored in the field of otolaryngology, particularly for chronic conditions such as tinnitus. This study aims to investigate the influence of spiritual and religious beliefs on symptom severity, quality of life, and mental health of Brazilian patients with chronic subjective tinnitus.</p><p><strong>Methods: </strong>Cross-sectional study including patients with chronic subjective tinnitus.</p><p><strong>Setting: </strong>Specialized outpatient center in Brazil. Religious and spiritual variables (Duke Religion Index, FACIT-Sp 12, and SRCOPE - religious coping) were investigated on the relationship with tinnitus severity (Tinnitus Handicap Inventory), mental health (DASS-21), and quality of life (WHOQOL-Bref), adjusting for sociodemographics, clinical data, and physical examination findings. Linear Regression models were used.</p><p><strong>Results: </strong>A total of 313 patients were included. Spiritual well-being measures were associated with better results (particularly for Meaning and Peace); meanwhile, negative religious coping was associated with worse outcomes for all variables. Religiosity has presented a mixed effect, with nonorganizational religiosity having better outcomes for mental health and quality of life, and intrinsic religiosity having worse outcomes for tinnitus severity.</p><p><strong>Conclusion: </strong>The present study found that religious and spiritual beliefs can have an important influence on the perception of tinnitus severity, mental health, and quality of life of individuals with chronic tinnitus. These findings support the importance of otolaryngologists' and audiologists' understanding of their patients' beliefs to provide more comprehensive and integrative care.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251349411"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor Regarding \"Analysis of Content Related to Retrograde Cricopharyngeal Dysfunction on TikTok: Opportunities for Patient Education and Advocacy\".","authors":"Rachana Mehta, Ranjana Sah","doi":"10.1177/00034894251356132","DOIUrl":"https://doi.org/10.1177/00034894251356132","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251356132"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perineural Invasion of the Facial Nerve Presenting as Rapid-Onset Excruciating Facial Pain and Paralysis.","authors":"Evan Smith, David Adkins, Nikita Gupta, Quinn A Dunlap, Douglas Lukins, Nathan D Cass","doi":"10.1177/00034894251352731","DOIUrl":"https://doi.org/10.1177/00034894251352731","url":null,"abstract":"<p><strong>Objective: </strong>This case report describes an 82-year-old female presenting with sudden onset, total right-sided facial paralysis, later diagnosed as metastatic squamous cell carcinoma (SCC) with perineural invasion of the facial nerve. The case highlights the diagnostic challenges of facial paralysis with associated pain in elderly patients and underscores the importance of recognizing subtle imaging findings suggestive of malignancy.</p><p><strong>Methods: </strong>A retrospective review of the patient's clinical presentation, imaging studies, surgical intervention, and pathological findings was conducted.</p><p><strong>Results: </strong>The patient developed right-sided facial paralysis ten months prior to presentation, followed by progressive hearing loss, imbalance, and excruciating facial pain. Initial treatment, including intratympanic dexamethasone injections, failed to alleviate symptoms. Examination revealed a central tympanic membrane perforation, complete flaccid facial paralysis (House-Brackmann grade 6), and sensorineural hearing loss. Imaging showed subtle widening of the labyrinthine segment of the right facial nerve and geniculate ganglion on CT, with corresponding enhancement and a filling defect in the internal auditory canal (IAC) on MRI. The differential diagnosis included facial nerve schwannoma, hemangioma, atypical Ramsay Hunt syndrome, and metastatic SCC. Imaging findings prompted surgical biopsy via a transcanal endoscopic approach, which confirmed metastatic SCC. Despite targeted radiation therapy, the patient developed failure to thrive, transitioned to hospice, and passed away.</p><p><strong>Conclusion: </strong>This case emphasizes the need for thorough evaluation of atypical facial paralysis, particularly in elderly patients with a history of cutaneous malignancy. The presence of facial pain, progressive hearing loss, and imaging abnormalities should prompt consideration of perineural tumor spread. Early recognition and multidisciplinary management are critical for timely intervention and improved palliative care outcomes.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251352731"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genderising Research Data: Updating our Paradigm.","authors":"Jacqui Elizabeth Allen","doi":"10.1177/00034894251353094","DOIUrl":"https://doi.org/10.1177/00034894251353094","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251353094"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor on \"The Role of Sucralfate in Post-Tonsillectomy Pain in Children: A Scoping Review\".","authors":"Jerome R Lechien, Giovanni Salzano, Luigi Vaira, Antonino Maniaci, Maria R Barillari","doi":"10.1177/00034894251351855","DOIUrl":"https://doi.org/10.1177/00034894251351855","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251351855"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Imaging Review Predicts the Complex Venous Anatomy of the Submental Island Flap.","authors":"Abigale R Aldrich, Ashley M Dorneden, Nathan H Boyd, Garth T Olson, Noah P Syme","doi":"10.1177/00034894251345057","DOIUrl":"https://doi.org/10.1177/00034894251345057","url":null,"abstract":"<p><strong>Objectives: </strong>The submental island flap is a dependable option for head and neck reconstruction. Venous drainage depends on the submental vein, which typically drains into the facial vein and, subsequently, the internal jugular vein. Variations in venous anatomy often involve drainage into the anterior jugular or external jugular venous systems. This study evaluates the likelihood of encountering submental venous anatomy variants and the accuracy of preoperative imaging in identifying them.</p><p><strong>Methods: </strong>Twenty-two patients who underwent a submental island flap procedure at the University of New Mexico Hospital from 2015 through 2023 with defined submental venous anatomy were analyzed. Three surgeons, blinded to intraoperative findings, predicted venous anatomy from preoperative imaging, with inter-rater reliability assessed using Fleiss Kappa.</p><p><strong>Results: </strong>Fifteen patients exhibited typical venous anatomy. Four patients' submental venous vasculature showed drainage into the external jugular vein, and 3 into the anterior jugular vein. Imaging reviews showed accuracy rates of 72.23%, 90.91%, and 86.36%, respectively. Analysis of cases with CT scans yielded k = 0.46 (<i>P</i> < .001).</p><p><strong>Conclusion: </strong>The submental island flap is versatile and reliable but demonstrates common variant venous anatomy. Accurate imaging-based predictions can optimize surgical efficiency and outcomes.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251345057"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family Medicine Physician Understanding and Management of Head and Neck Cancer Survivorship Care: A National Assessment.","authors":"Matthew E Lin, Oluwatobiloba O Ayo-Ajibola, Ryan J Davis, Carlos X Castellanos, Jonathan D West, Niels C Kokot","doi":"10.1177/00034894251349413","DOIUrl":"https://doi.org/10.1177/00034894251349413","url":null,"abstract":"<p><strong>Objectives: </strong>To understand United States family medicine physicians' and trainees' awareness, understanding, and confidence in following HNC survivorship guidelines.</p><p><strong>Methods: </strong>Cross-sectional survey regarding FM provider awareness of HNC survivorship guidelines. The survey was distributed to FM mailing lists and national forums. Descriptive statistics were used to characterize responses.</p><p><strong>Results: </strong>Eighty-six-physician cohort of majority attending physicians (86.1%) reporting an average of 20.0 years in practice working in non-rural (75.6%) outpatient community medical centers (41.9%). Respondents rarely cared for HNC survivors - 4.9% of patients per provider on average. They were largely unaware of the updated AHNS guidelines (8.1%). Physicians were least aware of the importance of discussing sexual intimacy/dysfunction (29%), considering pituitary dysfunction among patients with prior skull base radiation (29.1%), and evaluating for thyroid dysfunction (54.65%). Physicians were generally aware of cardiovascular disease's impact on mortality risk (64.0%) and higher prevalence of lung cancer (60.5%) among HNC patients but were less aware of their increased risk of depression (45.4%) and suicide (39.5%). On a 5-point Likert scale, physicians endorsed high confidence in counseling about substance use cessation (mean = 3.67), screening for thyroid dysfunction (mean = 3.65), and low confidence in managing long-term effects of chemotherapy (mean = 1.48), radiotherapy (mean = 1.48), and surgery (mean = 1.47). Physicians endorsed moderate overall confidence in managing HNC patients (mean = 2.38).</p><p><strong>Conclusions: </strong>FM physicians are critical to HNC survivorship care but have a variable understanding of HNC survivorship guidelines. Increasing FM physicians' awareness and understanding of survivorship care will help to continue improvement in HNC survivors' quality of care and life.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251349413"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Curious Presentation of a Supraglottic Lymphatic Malformation: A Case Report.","authors":"Megan K Scharner, Hannah G Farmer, Emlyn I Diakow, Clarice S Clemmens","doi":"10.1177/00034894251348110","DOIUrl":"https://doi.org/10.1177/00034894251348110","url":null,"abstract":"<p><strong>Introduction: </strong>Lymphatic malformations (LMs) are not uncommon findings in neonates, with an estimated incidence of 1 in 2000 live births. Most LMs involving the airway are grossly symptomatic and are diagnosed either prenatally or immediately after birth. In cases of airway LMs that are not diagnosed perinatally, the child often experiences significant symptoms beginning at birth. This case report describes a child presenting with stridor and snoring at the age of 17 months, a timeframe and clinical picture making LM a less likely diagnosis.</p><p><strong>Case description: </strong>A 17-month-old female presented to the pediatric otolaryngology clinic after referral for stridor and snoring with concern for laryngomalacia. Stridor was first noted 6 to 12 months prior to evaluation and was associated with an uri. Her breathing was described as low-pitched biphasic stridor, worse upon inspiration, with biphasic noises both at rest and with activity. Awake flexible laryngoscopy was significant for supraglottic erythema and edema, thickened epiglottis and arytenoids, shortened AE folds, and arytenoid prolapse. Urgent formal airway evaluation with sleep endoscopy, and microlaryngoscopy with bronchoscopy demonstrated amorphous irregularity of the epiglottis extending into the base of tongue concerning for lm. MRI revealed a lesion at the base of tongue consistent with lm. Treatment with oral sirolimus was initiated, and the patient's symptoms significantly improved.</p><p><strong>Discussion: </strong>while most airway LMs are diagnosed perinatally, this case describes a later and more subtle presentation. This unique presentation suggests that clinical suspicion for LM should be considered in children with respiratory symptoms and prompt further diagnostic workup.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251348110"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Development and Validation of a Hybrid Simulation Model for Septoplasty Training\".","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1177/00034894251349697","DOIUrl":"https://doi.org/10.1177/00034894251349697","url":null,"abstract":"","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"34894251349697"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}