Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association最新文献

{"title":"Independent predictors of ICU admission, mortality, and intervention requirements in acute upper gastrointestinal bleeding.","authors":"Ibrahim M Alruzug, Manhal Aldeher, Shakir Bakkari, Thamer Aldarsouny, Khaled M AlQahtani, Abdulkreem A Alnasser, Rasha Alissa, Mohammed S Bin Ofaysan, Ameen M Jaddoh, Toufic Semaan, Alhumidi A Alenezi, Musthafa C Peedikayil","doi":"10.4103/sjg.sjg_200_25","DOIUrl":"10.4103/sjg.sjg_200_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"292-300"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the unique concerns of Arab patients with inflammatory bowel disease: A cross-sectional study and the case for region-specific support groups.","authors":"Nadeen M Omar, Mohamed N Alzaabi, Maryam A Alahmad, Mohammed N Quraishi","doi":"10.4103/sjg.sjg_182_25","DOIUrl":"10.4103/sjg.sjg_182_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"284-291"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic and clinical implications of metabolic dysfunction-associated steatotic liver disease management: Regional challenges and opportunities in Middle East and North Africa.","authors":"Mohamed El-Kassas, Faisal M Sanai","doi":"10.4103/sjg.sjg_247_25","DOIUrl":"10.4103/sjg.sjg_247_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"249-251"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-national comparison of inflammatory bowel disease burden in China, Japan, the United States, and India: An age-period-cohort analysis of GBD 2021.","authors":"Zhimei Sun, Biao Yin, Tianen Hou, Taofeng Jiang","doi":"10.4103/sjg.sjg_124_25","DOIUrl":"10.4103/sjg.sjg_124_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"274-283"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic retrograde cholangiopancreatography of geriatric patients with cholangitis: A single-center experience in central Saudi Arabia.","authors":"Abdulaziz Al Masoud, Georgios Zacharakis, Abdulrahman Al-Robayan, Ebtissam Al-Meghaiseeb, Reem Al-Amro, Hadeel Ghazal, Nabih Alansari, Nawaf Bin Mugren, Abdullah Alshablan, Amal Aldawish, Ali Alduhayshi","doi":"10.4103/sjg.sjg_205_25","DOIUrl":"https://doi.org/10.4103/sjg.sjg_205_25","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic retrograde cholangiopancreatography (ERCP) is an essential tool for managing biliary diseases, particularly in geriatric patients. However, limited data exists on its safety and efficacy in geriatric population in Saudi Arabia.</p><p><strong>Methods: </strong>This prospective study evaluated ERCP outcomes in patients aged ≥70 at Prince Sultan Military Medical City, Riyadh, between November 2023 and May 2025. Patients were categorized into two groups: 70-80 years and ≥81 years. Data collected included demographics, comorbidities, Charlson Comorbidity Index (CCI), American Society of Anesthesiologists status (ASA) physical status, Duke Activity Status Index (DASI), indications, procedural success, and 30-day complications (per Cotton's criteria).</p><p><strong>Results: </strong>Of 403 ERCPs, 363 (90.7%) were performed in patients ≥70 years old. Of those, 199 were aged 70-80 years (mean 77.67 ± 5.4 years) and 164 were aged 81-103 years (mean 87.36 ± 5.26 years). The ≥81 years age group had more males (120 of 164, 73.2% vs. 123 of 199, 61.8%; P = 0.022), lower DASI (14.8 vs. 25.12; P < 0.001), and higher comorbidity rate (156 of 164, 95.12% vs. 150 of 199, 75.38%; P < 0.001). Common indications and technique success rates were similar between groups. Overall complication rates did not differ significantly; post ERCP pancreatitis (PEP) was more frequent in younger than in the older group (8 of 199, 4.02% vs 2 of 164, 1.21%; P = 0.096). No 30-day ERCP-related mortality was reported in either group.</p><p><strong>Conclusions: </strong>ERCP was safe and effective in Saudi geriatric patients, including those ≥81 years, with complication rates indicating that age alone should not preclude its use when clinically indicated.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A risk score model for post-endoscopic retrograde cholangiopancreatography complications in elderly patients with choledocholithiasis.","authors":"Guanjun Zhang, Guanyi Zhang, Ke Meng, Min Zhu, Daya Zhang, Yuming Han, Yawen Liang, Dexin Chen, Mingyang Li","doi":"10.4103/sjg.sjg_231_25","DOIUrl":"https://doi.org/10.4103/sjg.sjg_231_25","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic retrograde cholangiopancreatography (ERCP) is the preferred treatment for choledocholithiasis. This study aimed to identify the independent risk factors for post-ERCP complications in elderly patients with choledocholithiasis and establish a risk score model.</p><p><strong>Methods: </strong>This study enrolled patients over the age of 75 with choledocholithiasis, who underwent ERCP at two hospitals. Multivariate logistic regression analysis was used to identify predictive factors and establish a weighted risk score model, which was then externally validated.</p><p><strong>Results: </strong>Five factors (Charlson comorbidity index ≥3, aspartate aminotransferase >the upper limit of normal, endoscopic papillary large balloon dilation, cannulation time >10 min, and multiple large stones) were identified as risk factors for post-ERCP complications. A seven-point score model was established, with a score of three or above considered high risk and less than three considered low risk. The areas under the receiver operating characteristic curve for the derivation and validation cohorts were 0.791 (95% CI, 0.742-0.794) and 0.876 (95% CI, 0.793-0.879), respectively, with sensitivities of 0.755 (95% CI, 0.660-0.831) and 0.901 (95% CI, 0.698-0.972), and specificities of 0.826 (95% CI, 0.791-0.856) and 0.854 (95% CI, 0.761-0.914), respectively.</p><p><strong>Conclusions: </strong>An easy-to-use score model was successfully derived to help predict the risk of post-ERCP complications in elderly patients with choledocholithiasis.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A chain is only as strong as its weakest link: Care pathways in colorectal cancer, from emergency interventions to preventive strategies.","authors":"Majid A Almadi, Muhammad F Mubarak","doi":"10.4103/sjg.sjg_234_25","DOIUrl":"10.4103/sjg.sjg_234_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"193-196"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144629418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between gastroesophageal reflux and chronic kidney disease: A meta-analysis of 4 million patients.","authors":"Andres Chaponan-Lavalle, Ambar Godoy, Jose M Estrada-Grossmann, Eduardo S Acosta, Yolanda Chaponan-Lavalle, Luis G Azañedo-Garcia, Karina Ordaya-Gonzales, Manuel Gonzales-Palomo, Fortunato S Príncipe-Meneses, Arjunmohan Mohan, Renato Beas, Jose Arriola-Montenegro","doi":"10.4103/sjg.sjg_133_25","DOIUrl":"10.4103/sjg.sjg_133_25","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) has been associated with higher risk of gastrointestinal disorders, particularly Gastroesophageal reflux disease (GERD). However, the magnitude of this association and the underlying mechanisms remains unclear.</p><p><strong>Methods: </strong>A systematic search was conducted across major databases from inception to November 2024. We included cross-sectional and case-control studies evaluating the relationship between CKD and GERD. Data were extracted and analyzed using a random-effects model to calculate pooled odds ratios (ORs) and prevalence rates. Study quality was assessed using the Newcastle-Ottawa Scale, and heterogeneity was evaluated using the Cochran's Q test and I² statistic.</p><p><strong>Results: </strong>Nine studies involving 4,650,709 participants were included. The pooled prevalence of GERD among CKD patients was 18% (95% CI: 0.10-0.26, I² =93.64%). The pooled crude OR for the association between CKD and GERD was 2.53 (95% CI: 1.30-4.92) and adjusted OR was 1.48 (95% CI: 1.05-2.08).</p><p><strong>Conclusion: </strong>This meta-analysis reveals a marginally significant association between CKD and GERD, highlighting higher prevalence of GERD among individuals with CKD. Furthers studies are needed to elucidate the underlying pathophysiological mechanisms and potential clinical implications.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"206-211"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The index endoscopic characteristics associated with gastric neoplasms in serial screening of upper gastrointestinal endoscopy.","authors":"Jung Huh, Su Hwan Kim, Kwang Woo Kim, Yun Jin Jeong, Dong Jun Oh, Dong Kee Jang, Heejoon Jang, Ji Bong Jeong, Ji Won Kim, Kook Lae Lee, Hyoun Woo Kang","doi":"10.4103/sjg.sjg_31_25","DOIUrl":"10.4103/sjg.sjg_31_25","url":null,"abstract":"<p><strong>Background: </strong>Although biennial upper gastrointestinal endoscopy is recommended for gastric cancer screening in Korea, data regarding the endoscopic characteristics associated with the diagnosis of gastric neoplasms in serial endoscopic screening are limited. We aimed to evaluate the index endoscopic characteristics associated with the diagnosis of gastric neoplasms and adequate gastric cancer screening interval.</p><p><strong>Methods: </strong>We retrospectively reviewed cases of the patients diagnosed with gastric neoplasms, who showed no evidence of gastric neoplasms on index endoscopy between October 2005 and December 2022. The indices of endoscopic characteristics were analyzed. Patients were stratified according to the interval between endoscopic examinations (≤1, 1-2, 2-3, and >3 years), and the proportion of adenoma, early gastric cancer (EGC) and advanced gastric cancer (AGC) was analyzed across groups.</p><p><strong>Results: </strong>A total of 331 lesions with histological diagnoses of gastric neoplasms (167 adenomas, 138 EGCs, and 26 AGCs) were included. The initial baseline endoscopic findings were as follows: normal, 22 (6.7%); gastritis, 16 (4.8%); erosion, 65 (19.6%); ulcers, 19 (5.8%); atrophy, 104 (31.4%); and intestinal metaplasia, 105 (31.7%). The proportion of AGC increased with longer surveillance intervals: 0% at ≤1 year (median: 0.76 years, interquartile range [IQR]: 0.38), 3.1% at 1-2 years (1.59; 0.57), 6.7% at 2-3 years (2.37; 0.51), and 20.0% at >3 years (4.18; 1.53). Conversely, adenoma were most frequently detected within 1 year, comprising 63.6% ( P < 0.05).</p><p><strong>Conclusion: </strong>Cautious follow-up endoscopy may be necessary for patients demonstrating endoscopic findings of atrophy and intestinal metaplasia. Shorter surveillance intervals enable early detection of gastric neoplasia and may prevent progression to advanced cancer.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"219-226"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical outcomes of curative intent management in emergency vs. elective colon cancer: A retrospective single center study.","authors":"Noura S Alhassan, Thamer A Bin Traiki, Sulaiman A Alshammari, Mohaned Makkawi, Yazeed A Alkhayyal, Mohammed A Alswayyed, Maha-Hamadien Abdulla, Ahmad M Zubaidi, Omar A Al-Obeed, Reem A Alharbi, Khayal A AlKhayal","doi":"10.4103/sjg.sjg_101_25","DOIUrl":"10.4103/sjg.sjg_101_25","url":null,"abstract":"<p><strong>Background: </strong>Presentation affects several surgical parameters and post-operative outcomes. This study compares emergency versus elective colon cancer outcomes and prognostic factors associated with postoperative complications.</p><p><strong>Methods: </strong>All colon cancer patients who underwent curative resection between July 2015 and December 2019 were retrospectively reviewed and analyzed. Patients were divided into emergency and elective groups based on their presentation.</p><p><strong>Results: </strong>A total of 215 patients were included; 70 patients (32.6%) in the emergency group. Of them, 61 patients presented with obstruction, and nine with free perforation. The elective group had a higher laparoscopic approach (82.8%) with primary anastomosis (90.3%) compared to the emergency group (57.1% and 68.6%, respectively, P < 0.001). Postoperative complications were clinically higher in the emergency group (30% vs. 20.7%, P = 0.171). ICU/HDU admission was higher in the emergency group (40% vs. 17.2%, P < 0.001), and had a longer hospital stay (15 vs. 10 days, P < 0.003). Regression analysis revealed increased risk of complications among patients with comorbidities (OR 3.21; 95% CI, P = 0.002), albumin levels <30g/dl (OR 2.20; 95% CI, P = 0.01), complete obstruction (OR 2.42; 95% CI, P = 0.017), perforation (OR 9.98; 95% CI, P < 0.001), and open surgery (OR 4.84; 95% CI, P < 0.001).</p><p><strong>Conclusion: </strong>Emergency presentation rate was high among our patients with less-favorable surgical outcomes. Open surgery and stoma creation were more prevalent in the emergency group. Complete obstruction, perforation, open surgery, hypo-albuminemia, and presence of comorbidities were independent risk factors for complications.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"233-240"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}