Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)最新文献

{"title":"Defining the Undefined: Methodological Issues in the Genetic Study of Mediumship.","authors":"Yung Gonzaga, Vitor Souza, Leonardo Arcuri","doi":"10.47626/1516-4446-2025-4193","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4193","url":null,"abstract":"","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective Tax on Alcoholic Beverages in Brazil: The Next Step for an Effective Tax Policy to Reduce Health Harms.","authors":"Andre Akira Sueno Goldani, Zila Sanchez, Cristhian Ferreira Falleiro, Silvia Bassani Schuch-Goi, Felix Henrique Paim Kessler, Lisia von Diemen","doi":"10.47626/1516-4446-2025-4245","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4245","url":null,"abstract":"","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carol Sonenreich and Depression Psychopathology.","authors":"Felipe S Arruda, Igor Studart","doi":"10.47626/1516-4446-2025-4156","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4156","url":null,"abstract":"","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated movement analysis predicts transition to non-psychotic disorders in individuals at ultra-high risk for psychosis.","authors":"Ana Caroline Lopes-Rocha, Cheryl Mary Corcoran, Felipe Argolo, Andrea Fontes Jafet, Anderson Ara, João Medrado Gondim, Natalia Mansur Haddad, Leonardo Peroni de Jesus, Mauricio Henriques Serpa, Martinus Theodorus van de Bilt, Wagner Farid Gattaz, Guillermo Cecchi, Alexandre Andrade Loch","doi":"10.47626/1516-4446-2024-3919","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-3919","url":null,"abstract":"<p><strong>Objective: </strong>Ultra-high risk (UHR) criteria were developed to identify prodromal symptoms of psychosis, but most individuals do not transition. This highlights the need to identify transition markers like movement analysis. In the first stage of our study, movement analysis differentiated UHR from controls, showing reduced movement and increased erraticism. Our aim is to verify if these variables can predict UHR outcomes after follow-up.</p><p><strong>Methods: </strong>UHR individuals were recorded performing two speech tasks at baseline. Videos were analyzed using motion energy analysis (MEA) for head and torso movements-mean amplitude, frequency, and variability-and manually coded for gesticulation. After follow-up, 7 UHR converted to psychosis, 21 to other DSM-5 disorders (GD), and 18 did not convert (NC).</p><p><strong>Results: </strong>The GD group showed lower torso frequency and higher variability in both regions compared to Psychosis, as well as greater variability for torso when compared with NC. No differences were found between Psychosis and NC. Gesticulation did not differ between groups.</p><p><strong>Conclusions: </strong>Baseline movement variability distinguishes UHR transition outcomes, with higher variability seen in those converting to non-psychotic disorders. This supports the importance of movement analysis as a potential transition marker and suggests that treating UHR individuals as a single group may overlook important information.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Care Utilization and All-cause Mortality among Older Adults with Major Psychiatric Disorders: A 5-year Prospective Multicenter Study.","authors":"Katayoun Rezaei, Marina Sánchez-Rico, Pierre Lavaud, Cécile Hanon, Emmanuel Leleu, Frédéric Limosin, Nicolas Hoertel","doi":"10.47626/1516-4446-2025-4114","DOIUrl":"https://doi.org/10.47626/1516-4446-2025-4114","url":null,"abstract":"<p><strong>Objective: </strong>As the population ages, the number of older adults with psychiatric disorders in long-term care facilities is expected to importantly increase. To our knowledge, no study to date has examined the association of long-term care utilization with all-cause mortality among older adults with psychiatric disorders.</p><p><strong>Methods: </strong>In this report, we used data from the \"Cohort of individuals with Schizophrenia, bipolar and major depressive disorder aged 55 years or more (CSA)\", a 5-year prospective multicenter study, to examine this association. All analyses were adjusted for a wide range of potential confounders, including sociodemographic and clinical characteristics, and psychotropic medication use.</p><p><strong>Results: </strong>The prevalence of long-term care utilization was 23.6% (n=132) among 559 older adults with major psychiatric disorders. Living in long-term care utilization was significantly and independently associated with increased all-cause mortality in both the crude (OR=2.54; 95%CI=1.67-3.87; p<0.001) and fully-adjusted multivariable logistic regression models (AOR=1.86; 95%CI=1.10-3.16; p=0.021). This association did not significantly vary across most subgroups defined by sociodemographic and clinical characteristics.</p><p><strong>Conclusions: </strong>In this multicenter prospective observational study of older adults with major psychiatric disorders, long-term care utilization was significantly associated with increased all-cause mortality. Physicians and policy makers should take this association under careful consideration.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-person pronouns as linguistic markers of depression among Brazilian youths.","authors":"Anna Viduani, Victor Cosenza, Helen L Fisher, Claudia Buchweitz, Natália Mota, Jader Piccin, Rivka Pereira, Brandon A Kohrt, Valeria Mondelli, Alastair van Heerden, Ricardo Matsumura Araújo, Christian Kieling","doi":"10.47626/1516-4446-2024-4058","DOIUrl":"https://doi.org/10.47626/1516-4446-2024-4058","url":null,"abstract":"<p><strong>Objective: </strong>Major depressive disorder (MDD) is a leading cause of disability among youth, yet identifying this condition remains challenging. Naturalistic communication offers a promising approach to enhance depression detection. Increased use of first-person singular pronouns (e.g., ''I'') has been linked to MDD, but its applicability to younger, non-English-speaking populations remains unclear.</p><p><strong>Methods: </strong>This study examined first-person pronoun use in Brazilian Portuguese-speaking adolescents with and without MDD and its relationship to self-reported and clinician-rated depressive symptoms. Fifty-two adolescents (13 with and 39 without MDD) from the Identifying Depression Early in Adolescence Risk Stratified Cohort (IDEA-RiSCo) sample completed remote data collection using a WhatsApp chatbot, responding to questions via audio recordings. Transcripts were analyzed using the Linguistic Inquiry and Word Count (LIWC).</p><p><strong>Results: </strong>The MDD group used significantly more I-pronouns than non-MDD subjects (9.15 vs. 8.02%, t = -2.302, p = 0.026). Self-reported depressive symptomatology correlated with I-pronoun use (rho = 0.366, p = 0.008), but did not reach statistical significance for clinician-rated symptoms (rho = 0.248, p = 0.076).</p><p><strong>Conclusions: </strong>These findings support first-person singular pronouns as a potential linguistic marker of depression among Brazilian adolescents. This is the first study to replicate such results in a young, non-English-speaking sample using spoken speech, suggesting that integrating linguistic analysis with digital tools could enhance early detection efforts, particularly in resource-limited settings. Future research should explore use of I-pronouns alongside other linguistic and acoustic features to refine digital mental health screening approaches.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":"47 ","pages":"e20244058"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of observational, naturalistic, and neurophysiological outcome measures of nonpharmacological interventions for autism.","authors":"Priscilla Brandi Gomes Godoy,&nbsp;Fernando Mitsuo Sumiya,&nbsp;Leonardo Seda,&nbsp;Elizabeth Shephard","doi":"10.47626/1516-4446-2021-2222","DOIUrl":"https://doi.org/10.47626/1516-4446-2021-2222","url":null,"abstract":"<p><strong>Objective: </strong>Naturalistic and neurophysiological assessments are relevant as outcome measures in autism intervention trials because they provide, respectively, ecologically valid information about functioning and underlying neurocognitive mechanisms. We conducted a systematic review to highlight which specific neurophysiological techniques, experimental tasks, and naturalistic protocols have been used to assess neural and behavioral functioning in autism intervention studies.</p><p><strong>Methods: </strong>Studies were collected from four electronic databases between October 2019 and February 2020: MEDLINE (via PubMed), PsycINFO, LILACS, and Web of Science, and were included if they used structured observational, naturalistic, or neurophysiological measures to assess the efficacy of a nonpharmacological intervention for ASD.</p><p><strong>Results: </strong>Fourteen different measures were used by 64 studies, with the Autism Diagnostic Observation Schedule the most frequently used instrument. Thirty-seven different coding systems of naturalistic measures were used across 51 studies, most of which used different protocols. Twentyfour neurophysiological measures were used in 16 studies, with different experimental paradigms and neurophysiological components used across studies.</p><p><strong>Conclusions: </strong>Cross-study variability in assessing the outcomes of autism interventions may obscure comparisons and conclusions about how different behavioral interventions affect autistic social communication and underlying neurophysiological mechanisms.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":"532-547"},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/90/b9/bjp-44-05-532.PMC9561836.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40395333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immature defense mechanisms predict poor response to psychotherapy in major depressive patients with comorbid cluster B personality disorder.","authors":"Carolina Rheingantz Scaini,&nbsp;Igor Soares Vieira,&nbsp;Rosiene Machado,&nbsp;Taiane de Azevedo Cardoso,&nbsp;Thaise Mondin,&nbsp;Luciano Souza,&nbsp;Mariane Lopez Molina,&nbsp;Karen Jansen,&nbsp;Ricardo Azevedo da Silva","doi":"10.47626/1516-4446-2021-2214","DOIUrl":"https://doi.org/10.47626/1516-4446-2021-2214","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of defense mechanisms at baseline on depressive symptoms after brief psychotherapies and after 6-months of follow-up among depressed patients with and without cluster B personality disorders (PDs).</p><p><strong>Methods: </strong>This quasi-experimental study nested within a randomized clinical trial included a clinical sample of adults (18-60 years) diagnosed with major depressive disorder using the Mini-International Neuropsychiatric Interview. The Millon Clinical Multiaxial Inventory-III was applied to assess PD, the Defense Style Questionnaire 40 was used to analyze defense mechanisms, and the Beck Depression Inventory was used to measure the severity of depressive symptoms. Adjusted analysis was performed by linear regression.</p><p><strong>Results: </strong>The final sample consisted of 177 patients diagnosed with major depressive disorder, of whom 39.5% had cluster B PDs. Immature defenses at baseline significantly predicted the persistence of depressive symptoms at post-intervention and at 6-months of follow-up only in patients with PDs.</p><p><strong>Conclusion: </strong>In depressed patients with cluster B PDs, immature defenses predicted a poor response to brief therapies. The assessment of immature defenses at baseline can help identify patients at greater risk of poor therapeutic results and enable more appropriate treatment choices.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":"469-477"},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/c8/bjp-44-05-469.PMC9561829.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40550945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mind possessed: well-being, personality, and cognitive characteristics of individuals regularly experiencing religious possession.","authors":"Roma Delmonte,&nbsp;Miguel Farias,&nbsp;Marco Aurélio V Bastos,&nbsp;Leandro Madeira,&nbsp;Beatriz Sonego","doi":"10.47626/1516-4446-2021-2414","DOIUrl":"https://doi.org/10.47626/1516-4446-2021-2414","url":null,"abstract":"<p><strong>Objective: </strong>To further our understanding of religious possession experiences by focusing on personality, cognitive, and quality of life outcomes.</p><p><strong>Methods: </strong>Data collection was undertaken at Umbanda sessions in Brazilian cities. Participants were mediums who regularly experienced possession (n=334) or those who attended the same rituals but had never been possessed (n=54).</p><p><strong>Results: </strong>We found that mediums were not significantly different across variables from the control group, except for anxiety, which was lower among mediums. Correlational and regression analysis showed that the level of meaningfulness attributed to possession and fusion with the spiritual entity were strongly positively correlated with most quality-of-life dimensions, and negatively with anxiety; in addition, level of meaningfulness predicted lower anxiety, and psychological quality of life was predicted by level of fusion and meaningfulness. Contrary to expectations, there were no detrimental effects of a lower level of bodily control over the possession experience.</p><p><strong>Conclusion: </strong>Together, these results suggest that individuals regularly experiencing possession within a religious context are psychologically similar to those who attend the same rituals without experiencing possession, and that the way they appraise their experiences as meaningful, as well as the level of spiritual fusion, are predictors of well-being.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":"486-494"},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a6/b6/bjp-44-05-486.PMC9561835.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40665080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory cytokines and alcohol use disorder: systematic review and meta-analysis.","authors":"Helena F Moura,&nbsp;Fernanda Hansen,&nbsp;Fabiana Galland,&nbsp;Daiane Silvelo,&nbsp;Fernando P Rebelatto,&nbsp;Felipe Ornell,&nbsp;Raffael Massuda,&nbsp;Juliana N Scherer,&nbsp;Felipe Schuch,&nbsp;Felix H Kessler,&nbsp;Lisia von Diemen","doi":"10.47626/1516-4446-2021-1893","DOIUrl":"https://doi.org/10.47626/1516-4446-2021-1893","url":null,"abstract":"<p><strong>Objective: </strong>To assess differences in blood inflammatory cytokines between people with alcohol use disorder (AUD) and healthy controls (HC).</p><p><strong>Methods: </strong>Searches were performed from inception through April 14, 2021. Meta-analyses with random-effects models were used to calculate the standardized mean difference ([SMD], 95%CI), and potential sources of heterogeneity were explored trough meta-regressions and subgroup analysis.</p><p><strong>Results: </strong>The meta-analysis included 23 studies on the following 14 cytokines: tumor necrosis factor (TNF)-a, IL-1, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-13, IL15, interferon (IFN)-g and sCD14. There were significantly higher concentrations of IL-6 (n=462 AUD and 408 HC; SMD = 0.523; 95%CI 0.136-0.909; p = 0.008) in AUD than HC. No significant differences were found in the other 13 cytokines.</p><p><strong>Conclusion: </strong>We found that IL-6 levels were significantly higher in individuals with AUD than HC and that other cytokines were not altered. This can be explained by the small number of studies, their methodological heterogeneity, and confounding factors (active use, abstinence, quantity, and physical or psychiatric illnesses, for example). Despite a great deal of evidence about alcohol and inflammatory diseases, studies assessing the role of neuroimmune signaling in the development and severity of AUD are still lacking.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":"548-556"},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e3/1d/bjp-44-05-548.PMC9561830.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40418101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}