Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions最新文献

{"title":"Transfemoral Transcatheter Aortic Valve Implantation (TF-TAVI) for Patients With Left Ventricular Assist Device (LVAD) and Aortic Regurgitation.","authors":"Daniel Tai-Leung Chan, Ho-On Alston Conrad Chiu, Ka-Lam Wong, Ka-Chun Un, Kwong-Yue Eric Chan, Shu-Yue Sze, Chor-Cheung Frankie Tam, On-Yat Wong, Gilbert H L Tang, Simon Cheung-Chi Lam","doi":"10.1002/ccd.70213","DOIUrl":"https://doi.org/10.1002/ccd.70213","url":null,"abstract":"<p><p>Aortic regurgitation (AR) develops in up to 25%-30% of patients with left ventricular assist device (LVAD). Treatment remains challenging since surgery confers significant peri-operative risk and the lack of valvular calcification renders transfemoral transcatheter aortic valve implantation (TF-TAVI) with non-dedicated devices technically challenging. We present a case series wherein a TF J-Valve system, a dedicated transcatheter heart valve for pure AR, emerges as an alternative treatment for AR in patients with an LVAD. We demonstrate successful deployment even in the presence of challenging anatomy including aortic root thrombus. Technical considerations when performing TF-TAVI in LVAD patients are discussed.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Outcome of Coronary Orbital Atherectomy in Diabetic Versus Non-Diabetic Patients: A Single-Center Experience.","authors":"Benjamin Klein, Sri Mandava, Rachel Shatanof, Selin Sendil, Amre Ghazzal, Zsuzsanna Igyarto, Brad J Martinsen, Ajay J Kirtane, Martin B Leon, Nirat Beohar","doi":"10.1002/ccd.70210","DOIUrl":"https://doi.org/10.1002/ccd.70210","url":null,"abstract":"<p><strong>Background and aims: </strong>Clinical trial research on the safety and efficacy of coronary orbital atherectomy (OA) in diabetics compared to non-diabetics is limited. This single-center study aimed to perform a diabetic comparative analysis using real-world data.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on consecutive patients undergoing coronary OA treatment for severely calcified lesions at Mount Sinai Medical Center, Miami Beach, Florida (MSMCMB), from January 2014 to September 2020. Severe angiographic complications, bleeding complications, in-hospital heart failure and cardiogenic shock were reviewed. Major adverse cardiac and cerebrovascular events (MACCE), including cardiac death, MI, and cerebrovascular accident (CVA) were assessed in-hospital and at 1- and 2-year follow-up.</p><p><strong>Results: </strong>A total of 609 patients who underwent percutaneous coronary intervention with OA were identified. Among them, 43% were diabetic with a median age of 75 for both cohorts. In the diabetic cohort, there was a higher prevalence of Hispanics (66% vs. 51%; p < 0.001), dyslipidemia (81% vs. 72%; p = 0.005), and hypertension (94% vs. 89%; p = 0.033). There were no significant differences between the two groups in terms of severe angiographic complications, bleeding complications, in-hospital MACCE or MACCE at 1- and 2-year follow-ups.</p><p><strong>Conclusions: </strong>This real-world comparative analysis suggests that coronary OA is a safe and effective plaque modification technique in diabetic patients with severely calcified coronary artery disease, with outcomes comparable to those of non-diabetics.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of in-Hospital Complication Rates After Transcatheter Aortic Valve Replacement in Patients With Bicuspid Versus Tricuspid Aortic Valves: A Retrospective Cohort Study.","authors":"Tingxi Zhu, Jiawei Luo, Xuan Huang, Lulu Liu, Kehan Li, Wei He, Xiaobo Zhou, Yingqiang Guo, Xiaoyan Yang","doi":"10.1002/ccd.70206","DOIUrl":"https://doi.org/10.1002/ccd.70206","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter aortic valve replacement (TAVR) has become a popular alternative to surgical aortic valve replacement (SAVR) for patients with valvular heart disease (VHD), particularly for those with aortic anomalies.</p><p><strong>Aims: </strong>The study aimed to compare the risks of post-TAVR complications between patients with bicuspid and tricuspid aortic valves and to identify associated risk factors.</p><p><strong>Methods: </strong>The association between complications and valve type (bicuspid or tricuspid) was assessed. The study also explored various combinations of factors to understand their impact on complications. Separate analyses were conducted to identify specific risk factors for each complication.</p><p><strong>Results: </strong>Out of the 1154 eligible patients, 508 had bicuspid aortic valves (BAV) and 646 had tricuspid aortic valves (TAV). The study identified 40 cases of acute kidney injury, 134 instances of new-onset permanent pacemaker implantations, 129 occurrences of paravalvular leak, and 30 device successes. The comprehensive logistic regression revealed no statistically significant association between complications and valve type (ORs: 0.52 (95% CI, 0.23-1.09) for acute kidney injury, 1.29 (95% CI, 0.87-1.92) for permanent pacemaker implantation, 1.29 (95% CI, 0.82-2.02) for paravalvular leak, and 0.54 (95% CI, 0.22-1.23) for device success). Total bilirubin (TBIL), albumin (ALB), age, and New York Heart Association (NYHA) scores, among other factors, were associated with specific post-TAVR complications.</p><p><strong>Conclusions: </strong>The incidence of acute kidney injury, new permanent pacemaker implantations, paravalvular leaks, and device success did not differ significantly between patients with BAV and TAV following TAVR. Specific risk factors for these complications were identified, highlighting the importance of careful clinical monitoring in post-TAVR management.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular Interventional Thrombolysis Combined With Mild Hypothermia Induced by Intravascular Hypothermia Saline Fails to Improve Outcomes in the Acute Large Vessel Occlusive Cerebral Infarction Patients: A Single-Center Prospective Case-Control Study.","authors":"Jiang Li, Wei Zhang, Shao-Nian Tang, Lin-Fa Chen, Juan-Li Liu, Ting-Ting Mao, Xue-Song Li, Li-An Huang","doi":"10.1002/ccd.70217","DOIUrl":"https://doi.org/10.1002/ccd.70217","url":null,"abstract":"<p><strong>Background: </strong>The mild hypothermia for thrombolysis in patients with cerebral infarction caused by acute large-vessel occlusion is superior to the standard medical treatment.</p><p><strong>Aims: </strong>The safety and effectiveness of cytoprotection and prognosis from the hypothermia is under investigation.</p><p><strong>Methods: </strong>Twenty-five patients with acute occlusion of intracranial large vessels treated with endovascular thrombolysis of hypothermic saline infusion within 24 h at the onset of the disease were enrolled as a treatment group. As a control group, 166 patients suffering from acute large-vessel occlusion and infused with normal temperature saline at the hospital during the same period were selected. The patients were paired according to gender, age, pathogenesis, offending vessel, risk factors, and combined underlying diseases. The baseline data were recorded and compared between the two groups. The pre- and postprocedure contents and prognosis of patients were recorded and compared for safety assessment.</p><p><strong>Results: </strong>Twenty pairs of patients were rigorously matched into the final statistical analysis. There was a significant decrease in the hematocrit difference of treatment group compared with the control group. However, we found no significant differences between the two groups regarding 7-day postoperative NIHSS scores, incidence of pneumonia, rate of CT abnormalities in the immediate postoperative period, the rate of 7-day postoperative head CT hemorrhage, the occurrence of severe cerebral edema, and 90-day postoperative mRS scores.</p><p><strong>Conclusions: </strong>Targeted intravascular subcryogenic temperature combined with arterial thrombolysis is safe for the treatment of large-vessel occlusive cerebral infarction, but the treatment fails to improve outcomes in the acute large vessel occlusive cerebral infarction patients.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Year Outcome of Drug Coated Balloon Angioplasty Following Atherectomy for Severely Calcified Coronary Lesions.","authors":"Taka-Aki Takamura, Chihiro Nakagawa, Miharu Masaki, Satori Akita, Minako Oda, Minoru Wakasa, Hironobu Akao, Michihiko Kitayama, Taketsugu Tsuchiya, Toshiki Ichikawa, Shunsuke Takama, Tohru Nakagawa","doi":"10.1002/ccd.70196","DOIUrl":"https://doi.org/10.1002/ccd.70196","url":null,"abstract":"<p><p>We aimed to compare the long-term efficacy and safety of drug-coated balloon (DCB) and drug-eluting stent (DES) following atherectomy for coronary arteries with severely calcified lesions. Of the 258 consecutive patients and 422 de novo lesions treated with DCB at Kanazawa Medical University Hospital, we retrospectively enrolled highly calcified de novo lesions treated with atherectomy, rotablator, and/or orbital atherectomy system (OAS), followed by the use of either DCB (94 cases, 191 lesions) or DES (159 cases, 216 lesions) were retrospectively examined. The primary endpoint was target lesion revascularization (TLR), and the secondary endpoint was major adverse cardiac event (MACE) during 3 years of follow-up. Regarding patient background, there was a significant difference in age (All DCB vs. DES: 69.5 ± 11.4 vs. 73.2 ± 8.6; p < 0.001), and the DCB group included more dialysis cases (28.3% vs. 15.3%; p < 0.01). No significant difference was observed in the lesion background. The balloon size of the DCB was 2.56 ± 0.40 mm. Acute closure was not observed after DCB. Late lumen loss (LLL) was -0.07 ± 0.34 mm (DCB) versus 0.46 ± 0.65 mm (DES). Late lumen engagement (LLE) was observed in 56 lesions (56/129 [43.4%]) in the DCB group. As adjunctive treatment after atherectomy for calcified lesions, no significant difference was observed in TLR (16.2% vs. 13.4%; log-rank, p = 0.08) and MACE (18.3% vs. 16.2%; log-rank, p = 0.13). For highly calcified coronary lesions, relative to DES, treatment with DCB after atherectomy could provide clinically acceptable favorable results in terms of TLR and MACE at 3 years.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Editor: The Effect of Dual Antiplatelet Therapy Duration on PCI Outcomes in Diabetics With a History of GI Bleed.","authors":"Garzeen Ghaffar","doi":"10.1002/ccd.70221","DOIUrl":"https://doi.org/10.1002/ccd.70221","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stiffness Parameters of the Radial Artery in Patients Undergoing Distal Transradial Coronary Angiography: A Duplex Ultrasonography Investigation.","authors":"Elton Soydan, Mustafa Akın","doi":"10.1002/ccd.70211","DOIUrl":"https://doi.org/10.1002/ccd.70211","url":null,"abstract":"<p><strong>Background: </strong>Distal radial artery (DRA) is a feasible access in coronary angiography.</p><p><strong>Aims: </strong>We aimed to determine the stiffness parameters of DRA and main radial artery (MRA) in pre and post-transradial catheterization by using ultrasonography.</p><p><strong>Methods: </strong>Patients admitted for elective distal transradial coronary angiography were consecutively enrolled from September to December 2020. Overall, Duplex analysis was assessed in 100 patients on admission and 24 h post-catheterization. Emerging two MRA occlusion and four DRA occlusion cases were excluded from statistical analysis. As a result, we had 98 measurements in MRA and 96 in the DRA adjusted for statistical analysis.</p><p><strong>Results: </strong>Systolic diameter of the DRA was smaller than the MRA as 2.21 ± 0.38 versus 2.38 ± 0.38 mm (p group < 0.001). These increased to 2.4 ± 0.46 and 2.75 ± 0.47 mm, respectively, following catheterization (p group-time = 0.006). Stiffness index of the DRA was higher than the MRA (30.3 ± 26.3 vs. 22.7 ± 25.1 p = 0.601). After catheterization, this parameter significantly increased in the MRA while being preserved in the DRA (p time-group 0.032). Inversely, distensibility showed a decrease in the MRA (p time-group = 0.001) with preservation in the DRA after catheterization (p = 0.422).</p><p><strong>Conclusion: </strong>DRA is smaller and shows higher stiffness index with lower distensibility than the MRA. Following catheterization, these parameters show preservation in the DRA, despite an impairment in the MRA.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redo-Transcatheter Aortic Valve Replacement With a 26 mm Sapien Valve in a 26 mm Evolut Valve to Correct Significant Paravalvular Leak via Transcarotid Access.","authors":"Charlene L Rohm, Aaron Williams, Susan Eagle, Anna Eid, Angela Lowenstern","doi":"10.1002/ccd.70212","DOIUrl":"https://doi.org/10.1002/ccd.70212","url":null,"abstract":"<p><p>An 84-year-old man with multiple comorbidities including severe aortic stenosis, heart failure with a reduced ejection fraction, severe peripheral artery disease with prior bilateral iliac artery stents, and trifascicular block presented for evaluation for aortic valve replacement. He was deemed high risk for surgical valve replacement. Preprocedural computed tomography angiography (CTA) for transcatheter aortic valve replacement (TAVR) planning demonstrated an annular area of 295 mm² and perimeter of 62 mm. There was significant slice misregistration on CT; thus, we performed multiple re-measurements in different phases of the cardiac cycle. The patient sized for either a 23 mm Evolut FX+ (16% oversizing) or a 26 mm Evolut FX+ (30% oversizing). The left and right coronary artery heights were 17 and 19 mm, respectively. Transfemoral access was not possible due to severely calcified stenotic lesions with a maximal diameter of 4.6 and 3.8 mm in the right and left common iliac artery, respectively. He underwent dual-chamber permanent pacemaker implantation 5 weeks before scheduled TAVR. With a multidisciplinary heart valve team, the patient underwent left transcarotid TAVR with a 26 mm Evolut FX+ valve with resultant moderate-severe paravalvular leak on transesophageal echocardiography (TEE) that did not improve despite multiple post-dilations with 22- and 24-mm balloons at the inflow of the valve. At this point, we re-evaluated the preprocedural CT, utilizing the noncardiac gated series which showed less slice misregistration. The annular area measured 504 mm² with a perimeter of 80 mm, thus sizing for a 26 mm Sapien 3 Ultra (3% oversizing). The next day, the patient underwent successful left transcarotid valve-in-valve TAVR with a 26 mm Sapien 3 Ultra valve deployed with the outflow positioned at node 6 of the Evolut valve. The valve was post-dilated with a 25 mm balloon, resulting in no paravalvular leak on TEE. This case highlights a safe and effective strategy to correct significant PVL post-TAVR with a larger 26 mm Sapien 3 Ultra valve inside a 26 mm Evolut FX+ valve.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Artery Fistulous Perforation Effectively Managed During Chronic Total Occlusion Recanalization: A Case Report.","authors":"Gao Haokao, Chen Genrui, Wang Huan, Li Chengxiang","doi":"10.1002/ccd.70171","DOIUrl":"https://doi.org/10.1002/ccd.70171","url":null,"abstract":"<p><strong>Background: </strong>Coronary perforation is a feared complication of chronic total occlusion-percutaneous coronary intervention (CTO-PCI), especially in large vessel perforations, which often require implantation of covered stents (CS). However, the deployment of multiple CSs may not always be effective. Therefore, identifying the underlying formation mechanism and providing feasible solutions are very meaningful.</p><p><strong>Case presentation: </strong>This case presented an Ellis II grade perforation during the mid-left anterior descending (LAD) artery segment during LAD CTO recanalization. Three CS were implanted around the perforation site. However, continuous extravasation persisted even after adequate post-dilation for CS. After identifying the potential fistulous perforation inlet, one drug-eluting stent (DES) was deployed from the distal left main trunk (LMT) to the proximal LAD to successfully seal the fistulous inlet and effectively resolve the effusion.</p><p><strong>Conclusion: </strong>Precisely identifying the existing fistulous perforation and sealing its inlet can effectively reduce the need for deployment of CS.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular Lithotripsy for Coral Reef Aorta and Chronic Mesenteric Ischemia: Case Report and Comprehensive Literature Review.","authors":"Dipankar Mukherjee, Bibhas Amatya, David J Spinosa","doi":"10.1002/ccd.70198","DOIUrl":"https://doi.org/10.1002/ccd.70198","url":null,"abstract":"<p><p>Chronic mesenteric ischemia (CMI) secondary to extensive paravisceral atherosclerosis is a rare but challenging vascular condition, often presenting with postprandial abdominal pain, weight loss, and claudication due to impaired blood flow. While surgical bypass is a standard treatment, it carries significant risks, particularly in patients with severe calcified vascular disease. Advances in endovascular techniques, including intravascular lithotripsy, offer less invasive alternatives for select cases. We describe the application of IVL in a patient with near-total paravisceral aortic occlusion involving the origins of the superior mesenteric, celiac, and bilateral renal arteries. A multidisciplinary endovascular-first approach integrated IVL, angioplasty, and embolic protection, abolishing the translesional gradient and restoring visceral and renal perfusion. One-year follow-up confirmed durable patency and symptom resolution. To contextualize this case, we reviewed published reports of IVL in visceral and paravisceral disease, which collectively demonstrate high technical success, symptomatic improvement, and acceptable short-term safety, though long-term durability data remain limited. This case illustrates the effective use of endovascular lithotripsy for extensive paravisceral atherosclerosis causing CMI. This paper adds to emerging evidence supporting the role of IVL in complex mesenteric and paravisceral interventions.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}