Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions最新文献

{"title":"Comment on \"Impact of Epicardial plaQUe Composition and geomeTry on Coronary hEmodynamics and Flow in Patients With Coronary Artery Disease (iEquate)\".","authors":"Mashal Naveed, Muhammad Shahid Saddique, Waleed Abdullah Khan, Mawra Naveed, Syed Muhammad Rayyan","doi":"10.1002/ccd.70229","DOIUrl":"https://doi.org/10.1002/ccd.70229","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critique on \"Efficacy of Cerebral Embolic Protection Device in Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis\".","authors":"Wareesha Azmat","doi":"10.1002/ccd.70224","DOIUrl":"https://doi.org/10.1002/ccd.70224","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Year Outcomes of Novel Transcatheter Edge-to-Edge Mitral Repair System in Patients With Functional Mitral Regurgitation.","authors":"Kai Xu, Da Zhu, Hong Jiang, Jing Chen, Shaoliang Chen, Junjie Zhang, Ben He, Yan Wang, Guosheng Fu, Jiyan Chen, Jian An, Jiancheng Xiu, Xiaogang Guo, Yue Li, Xiang Cheng, Ping Li, Yuguo Chen, Shenghua Zhou, Yingxian Sun, Bo Yu, Xiangbin Pan, Yaling Han","doi":"10.1002/ccd.70230","DOIUrl":"https://doi.org/10.1002/ccd.70230","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter edge-to-edge repair (TEER) improves outcomes in patients with heart failure and moderate-to-severe functional mitral regurgitation (FMR) who remain symptomatic despite the use of maximal doses of guideline-directed medical therapy (GDMT). The SQ-Kyrin-M system is a novel TEER device designed for FMR treatment.</p><p><strong>Aims: </strong>This multicenter, prospective, single-arm study (ClinicalTrials.gov number: NCT05988450) evaluates the safety and efficacy of the SQ-Kyrin-M system in severe symptomatic FMR.</p><p><strong>Methods: </strong>A total of 125 eligible patients (mean age 65.5 ± 8.1 years) with heart failure and moderate-to-severe or severe FMR who remained symptomatic despite the use of maximal doses of GDMT were involved in the analysis. The primary endpoint was the composite rate of all-cause mortality and heart failure hospitalization at 1 year post-intervention. Independent assessments were conducted by an echocardiography core laboratory (ECL) and a clinical events committee (CEC).</p><p><strong>Results: </strong>At 1 year, the primary endpoint rate was 16.0% (20/125), and the composite major adverse event rate was 10.4%. Mitral regurgitation was reduced to ≤ 2+ in 94.2% of patients, with significant left ventricular reverse remodeling (LVEDV reduction: 33.8 ± 55.4 mL, p < 0.001). Patient-reported outcomes improved significantly, with Kansas City Cardiomyopathy Questionnaire (KCCQ) scores increasing by 15.9 ± 18.8 points (p < 0.001) and 6-minute walk distance (6MWD) improving by 46.7 ± 90.7 m (p < 0.001). The proportion of patients in New York Heart Association (NYHA) class I/II increased from 30.4% to 84.4% (p < 0.001).</p><p><strong>Conclusions: </strong>The SQ-Kyrin-M transcatheter mitral valve repair system bolsters the evidence supporting the safety and efficacy of TEER interventions for FMR patients.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pigtail Catheter Assistance in Guiding Catheter Navigation for Transradial Access for Embolization of Anterior Circulation Aneurysms.","authors":"Gang-Qin Xu, Tian-Xiao Li, Tong-Yuan Zhao, Jiang-Yu Xue, Liang-Fu Zhu, Zi-Liang Wang, Bu-Lang Gao","doi":"10.1002/ccd.70199","DOIUrl":"https://doi.org/10.1002/ccd.70199","url":null,"abstract":"<p><strong>Background: </strong>The effect and safety of pigtail catheter assistance in navigating the guiding catheter for embolization of anterior circulation aneurysms through the transradial access are unknown.</p><p><strong>Aims: </strong>This study was to evaluate the effect and safety of pigtail catheter assistance in navigating the guiding catheter for embolization of anterior circulation aneurysms through the transradial access.</p><p><strong>Methods: </strong>Seventy patients with intracranial aneurysms treated with endovascular embolization were retrospectively enrolled. The clinical, endovascular treatment and follow-up data were analyzed.</p><p><strong>Results: </strong>There were 70 aneurysms, including 47 (67.1% or 47/70) unruptured aneurysms and 23 (32.9% or 23/70) ruptured ones. The surgery was successful in 68 (97.1% or 68/70) patients, with a failure in two (2.9% or 2/70) patients. A 6 F guiding catheter was used in 28 (40% or 28/70) patients, and a 6 F intermediate catheter in 42 (60% or 42/70). Stent-assisted coiling was conducted in 50 (71.4% or 50/70) patients, and coiling alone in 20 (28.6% or 20/70). Immediately after embolization, complete occlusion was in 56 (80% or 56/70), neck remnant in 12 (17.1% or 12/70), and residual aneurysm sac in 2 (2.9% or 2/70). Periprocedural complications occurred in four (5.7% or 4/70) patients. Six-month angiographic follow-up was performed in 54 (77.1% or 54/70) patients with 54 aneurysms, and the Raymond-Roy aneurysm occlusion classification was complete occlusion in 46 (85.2% or 46/54), neck remnant in 8 (14.8% or 14/54), and residual aneurysm sac in 0, which was not significantly (p = 0.16) different from that immediately after embolization.</p><p><strong>Conclusion: </strong>The pigtail catheter assistance in guiding catheter navigation for embolizing anterior circulation aneurysms via the transradial access is safe and effective even though further confirmation is required.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Intravascular Lithotripsy With and Without Atherectomy in Severely Calcified Coronary Lesions Using OCT and OFDI.","authors":"Marohito Nakata, Masami Abe, Toshiya Chinen, Kentaro Nakamura","doi":"10.1002/ccd.70226","DOIUrl":"https://doi.org/10.1002/ccd.70226","url":null,"abstract":"<p><strong>Background: </strong>Intravascular lithotripsy (IVL) fractures calcified plaques and facilitates lesion expansion; however, unlike atherectomy devices, it does not reduce calcium volume. The therapeutic efficacy and safety of combining IVL with atherectomy remain unclear. Therefore, this study aimed to evaluate, through optical coherence tomography (OCT) or optical frequency domain imaging (OFDI), whether IVL combined with atherectomy provides greater effectiveness compared with IVL alone.</p><p><strong>Aims: </strong>This study aimed to evaluate, using optical coherence tomography (OCT) and optical frequency domain imaging (OFDI), whether intravascular lithotripsy (IVL) combined with atherectomy provides greater procedural efficacy and safety compared with IVL alone in the treatment of severely calcified coronary lesions.</p><p><strong>Methods: </strong>A retrospective analysis was performed on 33 lesions in 31 patients who underwent IVL-based percutaneous coronary intervention (PCI) with OCT or OFDI. The primary endpoints were post-PCI minimal lumen diameter (MLD) and minimal lumen area (MLA). The secondary endpoints included calcium fracture thickness, lesion expansion rate, and vessel expansion index.</p><p><strong>Results: </strong>The mean patient age was 72.3 ± 8.5 years, and 80.6% were men. No significant differences were identified in post-PCI MLD or MLA between the IVL alone and IVL + atherectomy groups (MLD: 2.46 ± 0.38 vs. 2.23 ± 0.56 mm; MLA: 4.9 ± 1.55 vs. 4.19 ± 1.90 mm²). The secondary endpoints were also comparable. However, the combination group demonstrated a longer procedural time (82.7 ± 19.6 vs. 109.8 ± 34.0 min) and a higher incidence of periprocedural myocardial infarction (0 vs. 3 patients).</p><p><strong>Conclusions: </strong>Combination therapy resulted in a longer procedural time and an increased incidence of myocardial injury. IVL alone may be sufficient in lesions where device delivery is feasible, whereas atherectomy should be performed when IVL delivery is challenging.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of CHA₂DS₂-VASc Score in Predicting Clinical Complications Following Primary Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis.","authors":"Dwi Ariyanti, Muhammad Farhan Hibatulloh, Cinday Kinanti Pramusinta, Achmad Ilham Tohari, Aqilla Sakanti Chandrarini, Muhammad Yusuf Fadhil, Yudi Her Oktaviono, I Gde Rurus Suryawan, Wynne Widiarti, Novia Nurul Faizah, Firas Farisi Alkaff, Pandit Bagus Tri Saputra","doi":"10.1002/ccd.70165","DOIUrl":"https://doi.org/10.1002/ccd.70165","url":null,"abstract":"<p><strong>Background: </strong>The CHA₂DS₂-VASc score was originally developed to assess stroke risk in patients with atrial fibrillation (AF). Recently, it has been explored as a potential tool for predicting adverse cardiovascular outcomes after percutaneous coronary intervention (PCI). However, its effectiveness in this context remains underexplored.</p><p><strong>Aims: </strong>This review aims to evaluate the ability of the CHA₂DS₂-VASc score to predict adverse cardiovascular outcomes in patients undergoing PCI.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted following PRISMA 2020 guidelines. Ten observational studies involving a total of 14,143 patients were included. The primary outcomes were ISR, AST, and MACE. Pooled odds ratios (ORs) or hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using random-effects models.</p><p><strong>Results: </strong>Most included studies were observational with varying endpoints, follow-up periods, and stent technologies, limiting causal inference, subgroup analyses, and introducing potential bias. The pooled analysis showed that higher CHA₂DS₂-VASc scores were significantly associated with increased risks of ISR (OR: 2.21; 95% CI: 1.75-2.78), AST (OR: 1.99; 95% CI: 1.53-2.60), and MACE (HR: 1.44; 95% CI: 1.22-1.69).</p><p><strong>Conclusion: </strong>The CHA₂DS₂-VASc score shows strong predictive value for ISR, AST, and MACE after PCI. Its simplicity and ease of use make it a practical tool for bedside risk assessment in clinical settings. Future prospective, multicenter studies with patient-level data are needed to validate the CHA₂DS₂-VASc score in non-AF populations.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Routine Use of Ultrasound in the Identification and Management of Thrombosis Following Pediatric Cardiac Catheterization.","authors":"D R Critchfield, G A Fleming, K D Hill, R C Chamberlain","doi":"10.1002/ccd.70225","DOIUrl":"https://doi.org/10.1002/ccd.70225","url":null,"abstract":"<p><strong>Background: </strong>Vessel occlusion post-catheterization is a common complication, yet there is no standard for diagnosis and treatment. As a result, there is variability in identification and management of post-catheterization thrombosis.</p><p><strong>Aims: </strong>We aimed to (1) describe a protocol using ultrasound (US) for the identification and managemetn of venous and arterial thrombosis and (2) evaluate risk factors for post-catheterization thrombosis.</p><p><strong>Methods: </strong>Single-center, retrospective review of patients ≤ 6 months undergoing cardiac catheterization from 2015 to 2020 following implementation of a surveillance and treatment protocol with routine US. We collected demographics, procedural and treatment details, and outcomes for protocol effectiveness. Mixed-effect multivariate logistic regression identified risk factors associated with venous and arterial thrombosis.</p><p><strong>Results: </strong>In total, 320 patients underwent 443 catheterizations with a mean age 2.9 months and weight 4.6 kg. A total of 755 vessels were accessed and US was obtained in 641/755 (84.9%) with thrombosis detected in 59/641 (9.2%); 26/338 (7.7%) venous and 33/303 (10.9%) arterial. In multivariate analysis, fluoroscopy time (aOR 1.02 per minute, CI 1.00-1.04) and smaller sheath size (aOR 0.48 per 1 French size, CI 0.26-0.83) predicted venous thrombosis. While larger sheath size (aOR 3.60 per 1 French size, CI 1.13-11.32) and lower weight (aOR 0.58 per kg, CI 0.41-0.82) were predictive for arterial thrombosis. Nearly all thrombi (56/59, 94.9%) were treated and thrombus resolution was noted in most (17/26, 65.4% venous, 27/33, 81.8% arterial). Of patients undergoing a future catheterization, a vessel with previous thrombosis was accessed in 14/23 (60.9%) venous and 15/30 (50.0%) arterial sites.</p><p><strong>Conclusions: </strong>A protocol of routine post-catheterization US and thrombus treatment in infants commonly identified venous and arterial thrombi-resolving the majority of thrombi identified.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Outcomes of Drug-Eluting Balloons Versus Drug-Eluting Stents in Patients With Diabetes Undergoing PPCI.","authors":"Hassan Shabeer, Saba Sattar, F N U Arti, Haimath Kumar, Kashif Iltaf, Muhammad Zaryab Haider, Burhan Ul Haq Saqib, Muhammad Hassan Bari, Ali Karim, Sameet Kumar, F N U Shweta, F N U Payal, F N U Rumela, Mehak Gul Mastoi, Abida Parveen","doi":"10.1002/ccd.70220","DOIUrl":"https://doi.org/10.1002/ccd.70220","url":null,"abstract":"<p><strong>Background: </strong>The comparative outcomes of DEB vs. DES in diabetic patients undergoing PPCI are of significant clinical interest, as these patients often experience higher rates of restenosis and adverse outcomes.</p><p><strong>Aims: </strong>This study aimed to compare the outcomes of drug-eluting balloons (DEB) versus drug-eluting stents (DES) in diabetic patients undergoing primary percutaneous coronary intervention (PPCI).</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 5668 diabetic patients who underwent PPCI, with 1734 patients in the DEB group and 3934 patients in the DES group. Baseline characteristics, angiographic features, and clinical outcomes, including procedural success, major adverse cardiovascular events (MACE), target lesion revascularization (TLR), restenosis, and bleeding complications, were compared between the two groups.</p><p><strong>Results: </strong>Both DEB and DES groups demonstrated high procedural success rates (97.6% and 98.4%, respectively), with no significant differences in MACE, death, myocardial infarction, or target vessel revascularization. Restenosis at 6 months occurred in 3.9% of the DEB group and 3.4% of the DES group (p = 0.21). Lesion length, diabetes duration, hypertension, and prior myocardial infarction were identified as significant predictors of adverse outcomes. Use of DES was associated with a higher risk of MACE, but this did not translate into significant differences in clinical outcomes.</p><p><strong>Conclusion: </strong>Both DEB and DES are effective and safe treatment options for diabetic patients undergoing PPCI, with comparable outcomes in terms of procedural success, MACE, and restenosis.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Antiplatelet Therapy in NSTEMI: Successfully Navigating the DAPT Dilemma.","authors":"Loreto L Calaquian, John-Henry L Dean, Stephanie A Howes, Ariana Y Ramirez, Robert J Chilton","doi":"10.1002/ccd.70218","DOIUrl":"https://doi.org/10.1002/ccd.70218","url":null,"abstract":"<p><p>Non-ST Segment Elevation Myocardial Infarction (NSTEMI) is a leading cause of morbidity and mortality worldwide despite advances in therapy, necessitating a careful balance between preventing ischemic events and minimizing bleeding risks. Dual Antiplatelet Therapy (DAPT) plays a critical role in reducing recurrent myocardial infarction (MI), stent thrombosis, and cardiovascular death. However, its benefits in preventing thrombotic events come with an increased risk of major bleeding complications. Precision medicine, using patient-specific data and risk stratification tools, allows for the clinicians to better tailor treatment to optimize efficacy while minimizing adverse outcomes. This approach ensures the most appropriate care for each patient, improving outcomes in NSTEMI management.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-Coated Balloon Versus Drug-Eluting Stent for De Novo Lesions of Large Coronary Arteries: A Systematic Review and Meta-Analysis of Angiographic and Clinical Outcomes.","authors":"Ahmed Hassan, Ahmed Mansour, Mohamed Hamouda Elkasaby, Shrouk Ramadan, Ahmed Nabil, Pannipa Suwannasom, Marwan Saad, Robbert J de Winter, Rayyan Hemetsberger, Mohammad Abdelghani","doi":"10.1002/ccd.70223","DOIUrl":"https://doi.org/10.1002/ccd.70223","url":null,"abstract":"<p><strong>Background: </strong>Efficacy of drug-coated balloons (DCBs) has been established in the treatment of in-stent restenosis and small vessel coronary artery disease, while utility in large-vessel de novo lesions remains controversial.</p><p><strong>Aims: </strong>We sought to study the angiographic and clinical outcomes after treatment of large vessel de novo coronary lesions with DCB versus drug-eluting stent (DES).</p><p><strong>Methods: </strong>We systematically searched electronic databases through March 2025 for relevant studies. Outcomes were compared using random effects modeling for summary estimates. We performed subgroup analyses by study design.</p><p><strong>Results: </strong>Our analysis included 16 studies (eight randomized controlled trials and eight observational) with 9745 patients. Follow-up duration was 17 ± 8 months for DCB and 16 ± 4 months for DES. While acute gain was significantly lower with DCB (MD = -0.45, 95% CI: -0.63 to -0.26; p < 0.00001; I² = 74%), no significant differences were observed in late lumen loss (MD = -0.03, 95% CI: -0.09 to 0.04; p = 0.47; I² = 47%) or binary restenosis (RR = 2.22, 95% CI: 0.94 to 5.24; p = 0.07; I² = 13%). Clinically, there was no significant difference between DCB and DES in target lesion failure and overall major adverse cardiac events, and this was consistent regardless of the study design (randomized vs. observational).</p><p><strong>Conclusion: </strong>Compared with DES, treatment with DCB yields a less optimal immediate angiographic result but comparable clinical outcomes in patients with de novo lesions of large coronary arteries.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}