Deniz Mutlu, Athanasios Rempakos, Dimitrios Strepkos, Pedro E P Carvalho, Michaella Alexandrou, Eleni Kladou, Ozgur Selim Ser, Lorenzo Azzalini, Farouc A Jaffer, Luiz Ybarra, Omer Goktekin, Mahmut Uluganyan, Ramazan Ozdemir, Basem Elbarouni, Khaldoon Alaswad, Rhian Davies, Ahmed ElGuindy, Cuneyt Kocas, Sefa Sural, Paul Poommipanit, Jarrod Frizzel, Mir B Basir, Leah Raj, Laura Young, Bavana V Rangan, Olga C Mastrodemos, Jaskanwal Deep Singh Sara, Sandeep Jalli, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis, Sevket Gorgulu
{"title":"Drug-Coated Balloons in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry.","authors":"Deniz Mutlu, Athanasios Rempakos, Dimitrios Strepkos, Pedro E P Carvalho, Michaella Alexandrou, Eleni Kladou, Ozgur Selim Ser, Lorenzo Azzalini, Farouc A Jaffer, Luiz Ybarra, Omer Goktekin, Mahmut Uluganyan, Ramazan Ozdemir, Basem Elbarouni, Khaldoon Alaswad, Rhian Davies, Ahmed ElGuindy, Cuneyt Kocas, Sefa Sural, Paul Poommipanit, Jarrod Frizzel, Mir B Basir, Leah Raj, Laura Young, Bavana V Rangan, Olga C Mastrodemos, Jaskanwal Deep Singh Sara, Sandeep Jalli, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis, Sevket Gorgulu","doi":"10.1002/ccd.70240","DOIUrl":"https://doi.org/10.1002/ccd.70240","url":null,"abstract":"<p><strong>Background: </strong>There is limited information on the use of drug-coated balloons (DCBs) in chronic total occlusion (CTO) percutaneous coronary intervention (PCI).</p><p><strong>Aims: </strong>To assess the frequency and outcomes of DCB use in CTO PCI.</p><p><strong>Objective: </strong>This study evaluated the frequency and outcomes of DCB use in a large, multicenter CTO PCI registry.</p><p><strong>Methods: </strong>We analyzed 12,146 patients who underwent 12,157 successful CTO PCIs at 59 centers from 2018 to 2025.</p><p><strong>Results: </strong>DCBs were used in 454 patients (3.7%) with increasing frequency over time (p = 0.020). A DCB-only strategy was used in 48.4% of the patients and a hybrid strategy combining DCBs and drug-eluting stents (DES) was used in 51.6% of patients. Patients treated with DCB (both strategies) had low prevalence of comorbidities. Compared with the DES cases, DCB only cases had favorable angiographic characteristics, lower mean J-CTO (Japanese CTO) score (1.83 ± 1.03 vs. 2.27 ± 1.23; p < 0.001), and similar technical success (96.3% vs. 97.3%; p = 0.640), and in-hospital major adverse cardiac events (MACE). The hybrid and DCB-only strategies had comparable technical success and in-hospital MACE. During a median follow-up of 323 (170-429) days, DCB only cases had lower MACE than the other strategies (hazard ratio [HR] 0.41, 95% CI 0.17-0.96, p = 0.040). After multivariable adjustment, the association remained significant (HR 0.39, 95% CI 0.16-0.92, p = 0.032).</p><p><strong>Conclusions: </strong>DCBs are increasingly being used in CTO PCI. A DCB only strategy was used in less complex lesions and was associated with similar technical success and in-hospital MACE compared with hybrid or DES strategies. A DCB only strategy was associated with lower long-term MACE.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145288036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Progressive Relaxation Exercise on Pain, Anxiety and Patient Satisfaction Related to Femoral Sheath Removal: A Randomized Controlled Study.","authors":"Sevda Korkut, Abdurrahman Oğuzhan","doi":"10.1002/ccd.70258","DOIUrl":"https://doi.org/10.1002/ccd.70258","url":null,"abstract":"<p><strong>Background: </strong>In percutaneous coronary intervention (PCI), the majority of patients experience pain and discomfort during the sheath removal in the femoral region after the intervention.</p><p><strong>Aims: </strong>This study aims to determine the effect of progressive relaxation exercises (PRE) on pain, anxiety, and patient satisfaction associated with femoral sheath removal in patients undergoing PCI.</p><p><strong>Methods: </strong>This is single-center, prospective, randomized controlled trial. This study was completed with a total of 70 patients. Data were collected using the Patient Information Form, Visual Analogue Scale and State-Trait Anxiety Inventory. Patients in the intervention group performed PRE for 20 min before femoral sheath removal. The patients in the control group received the standard care provided by the clinic.</p><p><strong>Results: </strong>The pain and anxiety levels of the intervention group were found to be significantly lower than the control group, while the satisfaction level was found to be significantly higher. After the intervention, the systolic blood pressure of the intervention group was found to be lower. In addition, anxiety before the application and the pain intensity experienced during femoral sheath removal were weakly positively correlated and satisfaction was weakly negatively correlated.</p><p><strong>Conclusions: </strong>According to the study results, PRE applied before the femoral sheath removal reduces pain and anxiety and increases patient satisfaction. PRE may be an effective intervention to prevent complications that may result from intense pain and anxiety experienced during femoral catheter removal.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reassessing Volume-Outcome Relationships in Multivessel ACS: Methodological Considerations.","authors":"Meerab Ali Khan, Hussnain Bilal","doi":"10.1002/ccd.70247","DOIUrl":"https://doi.org/10.1002/ccd.70247","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valeria Cosco, Giuseppe Grenci, Alessandro Fiorentino, Giuseppe Santarpino
{"title":"Limited Iatrogenic Dissection of the Aortic Root: To Treat or Not to Treat?","authors":"Valeria Cosco, Giuseppe Grenci, Alessandro Fiorentino, Giuseppe Santarpino","doi":"10.1002/ccd.70262","DOIUrl":"https://doi.org/10.1002/ccd.70262","url":null,"abstract":"<p><p>The treatment of aortic dissections of iatrogenic etiology still requires evaluation on a case-by-case basis, as the prevalence of these problems in the past was low, but has grown in recent years due to the exponential increase in hemodynamic procedures. Patients undergoing percutaneous hemodynamic procedures today are often elderly and also frail. Proposing \"conventional\" surgery to treat an acute aortic dissection may represent a request for \"surgical stress\" that is too high for their \"biological reserves.\" In addition to this, we assume that the physio-pathological mechanism that creates this type of dissection with a flap in the intima, compared to that of classic noniatrogenic dissections, is different in the angle of entry of the flap with formation of the false lumen, which has a consequent greater tendency to spontaneous \"self-resolution\" favored by physiological blood flow. In this paper, we present two cases of patients who underwent hemodynamic procedures (coronary angiography with angioplasty and transcatheter aortic valve implantation) both with limited iatrogenic dissection of the ascending aorta treated in a conservative nonsurgical manner. This approach resulted in the closure of the dissection line in both cases, demonstrating in one case the disappearance of the flap even at a 6-month follow-up.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julie Juul Siig, Marc Meller Søndergaard, Laust Dupont Rasmussen, Evald Høj Christiansen, Lars Jakobsen, Lisette Okkels Jensen, Jens Flensted Lassen, Niels Thue Olsen, Ole Ahlehoff, Kristian Hay Kragholm, Ashkan Eftekhari
{"title":"Prognosis of Calcified Lesions Treated With PCI in Patients With Chronic Coronary Artery Disease.","authors":"Julie Juul Siig, Marc Meller Søndergaard, Laust Dupont Rasmussen, Evald Høj Christiansen, Lars Jakobsen, Lisette Okkels Jensen, Jens Flensted Lassen, Niels Thue Olsen, Ole Ahlehoff, Kristian Hay Kragholm, Ashkan Eftekhari","doi":"10.1002/ccd.70245","DOIUrl":"https://doi.org/10.1002/ccd.70245","url":null,"abstract":"<p><strong>Background: </strong>Calcified coronary lesions are frequently seen in patients with comorbidities and pose a higher risk of complications during percutaneous coronary intervention (PCI).</p><p><strong>Aims: </strong>To evaluate the 5-year risk of acute myocardial infarction (MI) and all-cause mortality in patients with and without calcified lesions in patients with chronic coronary artery disease.</p><p><strong>Methods: </strong>Demographic, clinical, and procedural data were extracted from the Western Denmark Heart Registry (WDHR) for individuals with chronic coronary artery disease undergoing PCI from January 2000 to January 2021. Major exclusion criteria were prior MI and PCI. Patients were categorized according to presence of calcified lesions defined as visible calcium on angiography during the index procedure. The endpoint was MI and all-cause mortality.</p><p><strong>Results: </strong>In total, 16,757 patients underwent PCI due to chronic coronary artery disease of whom 5302 (32.6%) patients had calcified lesions and 11,455 (68.4%) patients had lesions without calcium. Patients with calcified lesions had significantly higher absolute 5-year risk of MI (15.6% (n = 826)) compared to patients without calcified lesions (12.8% (n = 1469)) (p < 0.0005). Patients with calcified lesions had significantly higher absolute 5-year risk for all-cause mortality (13.6% (n = 720)) compared to patients without calcified lesions (8.6% (n = 984)) (p < 0.0005).</p><p><strong>Conclusion: </strong>PCI of calcified lesions was associated with higher 5-year risk of MI and all-cause mortality.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left Ventricular Apical Thrombus in Apical Hypertrophic Cardiomyopathy Without Aneurysm or Arrhythmia: A Case Report.","authors":"Ibrahim Antoun, Jeffrey Khoo, Sanjay S Bhandari","doi":"10.1002/ccd.70265","DOIUrl":"https://doi.org/10.1002/ccd.70265","url":null,"abstract":"<p><p>Apical hypertrophic cardiomyopathy (ApHCM) is a rare variant of hypertrophic cardiomyopathy, typically associated with a benign course. However, complications such as ventricular arrhythmias, apical aneurysms, and thrombus formation may occur. Left ventricular (LV) thrombus is an unusual finding in ApHCM, especially in patients with preserved systolic function and normal sinus rhythm. A 54-year-old male with a history of pulmonary embolism and ApHCM was under routine surveillance. He remained asymptomatic with a normal sinus rhythm. Transthoracic echocardiography (TTE) identified an echogenic mass in the LV apex. Cardiac magnetic resonance imaging (CMR) confirmed severe apical hypertrophy, preserved LV systolic function, and a large apical mass measuring 24 × 19 mm. The mass showed no contrast uptake on early or late gadolinium enhancement sequences, consistent with thrombus. Native T1 mapping was mildly elevated, suggesting diffuse interstitial fibrosis, and focal non-ischaemic replacement fibrosis was noted. There was no evidence of apical aneurysm or mid-ventricular obstruction. The patient was anticoagulated with warfarin and remains under close follow-up. This case represents a rare occurrence of a large LV thrombus in ApHCM without associated apical aneurysm or impaired LV function. The findings suggest that regional fibrosis and altered apical flow dynamics may contribute to thrombus formation even in hypercontractile ventricles. Multimodal imaging, particularly CMR, is essential for accurate diagnosis and risk assessment. Clinicians should maintain vigilance for thrombotic complications in ApHCM, even in the absence of classical risk factors, as subtle fibrosis or flow abnormalities may predispose to thrombus formation.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145288101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implantation of Leadless Pacemaker in a Patient With Chronic Type A Aortic Dissection-A Case Report.","authors":"Xuehui Liu, Yue Luo, Xin Zhang, Xingbin Liu","doi":"10.1002/ccd.70222","DOIUrl":"https://doi.org/10.1002/ccd.70222","url":null,"abstract":"<p><p>When implanted into a structurally normal heart, leadless pacemakers are more effective and safer than traditional pacemakers. However, clinical experience with leadless pacemaker implantation in patients with severe right heart deformity remains limited. We present a rare case of an 87-year-old woman with right heart deformity (secondary to chronic Stanford type A aortic dissection) who successfully underwent implantation of a Micra leadless pacemaker. Preoperative computed tomography (CT) revealed compression of the right atrium by an ascending aortic root dissection aneurysm (maximum diameter: 7.2 cm) and clockwise rotation of the right heart. The delivery system was adjusted repeatedly during the operation, and angiography confirmed that the delivery system was in the right ventricle before releasing the pacemaker. Preoperative familiarity with distorted cardiac anatomy (via CT) and intraoperative angiographic verification of delivery system location are critical for safe leadless pacemaker implantation in patients with right heart deformity. These measures can effectively prevent complications such as cardiac perforation.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Catania, Salvatore Notaristefano, Alberto Barengo, Francesco Notaristefano
{"title":"All Roads Lead to Rome: Let's Choose the Safest One!","authors":"Francesco Catania, Salvatore Notaristefano, Alberto Barengo, Francesco Notaristefano","doi":"10.1002/ccd.70256","DOIUrl":"https://doi.org/10.1002/ccd.70256","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Taha Yahya, Ahmad Furqan Anjum, Suleman Arshad, Syed Ali Raza Zaidi
{"title":"Letter to the Editor: \"Safety and Efficacy of a Plug-Based Vascular Closure Device After Percutaneous Microaxial Flow Pump in the Treatment of Complex and High-Risk Indicated Patients\".","authors":"Taha Yahya, Ahmad Furqan Anjum, Suleman Arshad, Syed Ali Raza Zaidi","doi":"10.1002/ccd.70260","DOIUrl":"https://doi.org/10.1002/ccd.70260","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Off Label Use of EndoAnchors for the Treatment of Abdominal Aortic Aneurysm With Large-Barrel Neck.","authors":"Suko Adiarto, Ayers Gilberth Ivano Kalaij, Suci Indriani, Taofan","doi":"10.1002/ccd.70251","DOIUrl":"https://doi.org/10.1002/ccd.70251","url":null,"abstract":"<p><p>EVAR has replaced open surgical repair as the most commonly preferred definitive therapy for abdominal aortic aneurysm (AAA)s with suitable anatomy. However, the hostile neck has its own challenges in terms of treatment. Several endovascular techniques have been applied successfully to some of these hostile necks; however, none of these techniques are known to be used for large barrel necks. We presented a 73-year-old male with a large barrel neck AAA that was successfully treated with EVAR with EndoAnchors. Final procedural angiogram showed that the use of EndoAnchors were successful to completely exclude the aneurysms without evidence of endoleak. One-year follow-up CT revealed complete thrombosis of the aneurysmal sac and freedom from endoleak. EndoAnchors might be used to treat some large barrel neck AAAs. Through this case, we propose that the suitable anatomy would be: Diameter of \"secondary neck\" of less than 32 mm, absence of circumferential calcification and thrombus > 2 mm, the length of the \"secondary neck\" of at least 4 mm, and position of the secondary neck within 40-50 mm below the lowest renal artery.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}