局限性医源性主动脉根部夹层:治疗还是不治疗?

Valeria Cosco, Giuseppe Grenci, Alessandro Fiorentino, Giuseppe Santarpino
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引用次数: 0

摘要

医源性主动脉夹层的治疗仍然需要在个案基础上进行评估,因为这些问题的患病率在过去很低,但近年来由于血流动力学手术的指数增长而增长。今天接受经皮血流动力学手术的病人通常是老年人和体弱多病。建议用“传统”手术治疗急性主动脉夹层,可能意味着对“手术压力”的要求太高,超出了他们的“生物储备”。除此之外,我们假设,与经典的非医源性夹层相比,造成这种内膜皮瓣夹层的生理病理机制在皮瓣进入假腔形成的角度上有所不同,因此更倾向于生理血流的自发“自我溶解”。在本文中,我们报告了两例接受血流动力学手术的患者(冠状动脉造影合并血管成形术和经导管主动脉瓣植入术),均采用保守的非手术方式治疗有限的医源性升主动脉夹层。该入路导致两例剥离线关闭,其中一例甚至在6个月的随访中皮瓣消失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Limited Iatrogenic Dissection of the Aortic Root: To Treat or Not to Treat?

The treatment of aortic dissections of iatrogenic etiology still requires evaluation on a case-by-case basis, as the prevalence of these problems in the past was low, but has grown in recent years due to the exponential increase in hemodynamic procedures. Patients undergoing percutaneous hemodynamic procedures today are often elderly and also frail. Proposing "conventional" surgery to treat an acute aortic dissection may represent a request for "surgical stress" that is too high for their "biological reserves." In addition to this, we assume that the physio-pathological mechanism that creates this type of dissection with a flap in the intima, compared to that of classic noniatrogenic dissections, is different in the angle of entry of the flap with formation of the false lumen, which has a consequent greater tendency to spontaneous "self-resolution" favored by physiological blood flow. In this paper, we present two cases of patients who underwent hemodynamic procedures (coronary angiography with angioplasty and transcatheter aortic valve implantation) both with limited iatrogenic dissection of the ascending aorta treated in a conservative nonsurgical manner. This approach resulted in the closure of the dissection line in both cases, demonstrating in one case the disappearance of the flap even at a 6-month follow-up.

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