Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions最新文献

筛选
英文 中文
The Triglyceride-Glucose Index Stratifies Cardiovascular Risk After PCI: A Cohort Study Identifying the Highest-Risk Patients. 甘油三酯-葡萄糖指数对PCI术后心血管风险进行分层:一项确定高危患者的队列研究
Bowen Li, Zhihao Zheng, Jining He, Yanjun Song, Xiaohui Bian, Chenxi Song, Rui Fu, Kefei Dou
{"title":"The Triglyceride-Glucose Index Stratifies Cardiovascular Risk After PCI: A Cohort Study Identifying the Highest-Risk Patients.","authors":"Bowen Li, Zhihao Zheng, Jining He, Yanjun Song, Xiaohui Bian, Chenxi Song, Rui Fu, Kefei Dou","doi":"10.1002/ccd.70925","DOIUrl":"https://doi.org/10.1002/ccd.70925","url":null,"abstract":"<p><strong>Background: </strong>The triglyceride-glucose (TyG) index is a surrogate marker of insulin resistance, but its prognostic value across guideline-defined cardiovascular risk strata remains unclear.</p><p><strong>Methods: </strong>In this retrospective cohort study, 23,592 patients undergoing percutaneous coronary intervention (PCI) were stratified into non-high-risk (VHR0), high-risk (VHR1), and very-high-risk (VHR2) groups based on contemporary atherosclerotic cardiovascular disease criteria. The TyG index was evaluated as continuous and categorical (tertiles) variables. Primary endpoint was a 3-year composite of cardiovascular death, non-fatal myocardial infarction, or stroke (CV events).</p><p><strong>Results: </strong>During a median follow-up of 3.1 years, elevated TyG was independently associated with increased risks of CV events only in the VHR2 group (adjusted HR 1.51 for T3 vs. T1, 95% CI 1.10-2.08, p = 0.011). In VHR2 patients, adding TyG to a baseline risk model significantly improved reclassification (NRI 0.1251, p = 0.035) and discrimination (IDI 0.0028, p = 0.002). No significant associations were found in VHR0 or VHR1 groups.</p><p><strong>Conclusion: </strong>The TyG index independently predicts 3-year cardiovascular events specifically in very-high-risk patients after PCI and provides incremental prognostic utility, supporting its use for refined risk stratification and personalized secondary prevention in this high-risk population.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149122432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stepwise Percutaneous Management of a Giant Coronary Pseudoaneurysm. 巨大冠状假性动脉瘤的逐步经皮治疗。
Carmen Lluch-Requerey, Félix Rosa-Longobardo, Jessica Roa-Garrido, Antonio Enrique Gómez Menchero
{"title":"Stepwise Percutaneous Management of a Giant Coronary Pseudoaneurysm.","authors":"Carmen Lluch-Requerey, Félix Rosa-Longobardo, Jessica Roa-Garrido, Antonio Enrique Gómez Menchero","doi":"10.1002/ccd.70769","DOIUrl":"10.1002/ccd.70769","url":null,"abstract":"<p><p>Coronary pseudoaneurysms are rare but potentially life-threatening complications following coronary interventions. Their management presents significant technical challenges, particularly in frail patients with contraindications to surgery. This report describes the sequential percutaneous management of a giant acquired coronary pseudoaneurysm in a 74-year-old male with several comorbidities, including atrial fibrillation, aortic stenosis, and contraindication for open-heart surgery. Exclusion was achieved using covered stents, followed by left atrial appendage closure to allow withdrawal of anticoagulation. Moreover, during follow-up, transcatheter aortic valve implantation (TAVI) was performed due to severe symptomatic aortic stenosis. This case represents one of the largest coronary pseudoaneurysms reported in the literature and highlights the feasibility of an integrated imaging-guided percutaneous approach for the management of giant coronary pseudoaneurysms in high-risk patients. Left atrial appendage closure may have facilitated pseudoaneurysm thrombosis by enabling safe discontinuation of long-term anticoagulation, a hypothesis that warrants further investigation.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1301-1305"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148611962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From 360° Cap Hunting to a Targeted Arc: IVUS-Angio Co-Registration for Ambiguous CTO Entry. 从360°帽狩猎到目标弧:IVUS-Angio共同注册模棱两可的CTO条目。
Chin-Yuan Chia, Ming-Yun Ho, Jih-Kai Yeh, Chao-Yung Wang, Ming-Jer Hsieh, Chun-Chi Chen, I-Chang Hsieh
{"title":"From 360° Cap Hunting to a Targeted Arc: IVUS-Angio Co-Registration for Ambiguous CTO Entry.","authors":"Chin-Yuan Chia, Ming-Yun Ho, Jih-Kai Yeh, Chao-Yung Wang, Ming-Jer Hsieh, Chun-Chi Chen, I-Chang Hsieh","doi":"10.1002/ccd.70798","DOIUrl":"10.1002/ccd.70798","url":null,"abstract":"","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1405-1407"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Endovascular Revascularization of Aortoiliac Occlusive Disease With Favorable Outcome for Refractory Heart Failure After Axillary-Bifemoral Bypass Surgery: A Case Report. 腋窝-双侧搭桥术后难治性心力衰竭患者血管内血管重建成功
Hikaru Tanemura, Kazuki Tobita, Eiji Koyama, Hirokazu Miyashita
{"title":"Successful Endovascular Revascularization of Aortoiliac Occlusive Disease With Favorable Outcome for Refractory Heart Failure After Axillary-Bifemoral Bypass Surgery: A Case Report.","authors":"Hikaru Tanemura, Kazuki Tobita, Eiji Koyama, Hirokazu Miyashita","doi":"10.1002/ccd.70816","DOIUrl":"10.1002/ccd.70816","url":null,"abstract":"<p><p>Endovascular therapy for occlusive lesion might reduce cardiac afterload and improve cardiac function potentially, but there is limited evidence regarding its effects on heart failure, particularly in patients with poorly controlled symptoms. One month earlier, this 80-year-old woman with paroxysmal atrial fibrillation had undergone left axillo-bifemoral bypass for acute aortoiliac occlusion and was transferred to a rehabilitation hospital. After that, she was returned to our hospital after developing palpitations, dyspnea, and hypoxia during post-operative rehabilitation. Laboratory tests showed anemia, mild renal dysfunction, and markedly elevated B type natriuretic peptide. Chest radiography demonstrated bilateral pulmonary congestion. She was diagnosed to acute heart failure, and treatment with intravenous furosemide at a dose of 40 mg/day and oral amiodarone at a dose of 100 mg/day was initiated. Because sinus rhythm could not be maintained despite medical therapy and pulmonary vein isolation, atrioventricular node radiofrequency catheter ablation and cardiac resynchronization therapy pacemaker implantation were performed on hospital Day 12. However, exertional oxygen desaturation persisted, BNP remained elevated, and rehabilitation was limited by bilateral intermittent claudication. On hospital Day 22, endovascular therapy for aortoiliac occlusive disease was performed. Subsequently, additional endovascular therapy was undertaken for chronic total occlusion of the left superficial femoral artery. She was able to ambulate 20 m with support without any intermittent claudication (ankle-brachial index increased from 0.67 to 0.91 on the right and from 0.81 to 0.98 on the left). Oxygen demand also gradually decreased (from 1 L/min to room air), and B type natriuretic peptide levels declined. Both systolic and diastolic blood pressure improved, and the patient was transferred back to the rehabilitation hospital on hospital Day 54 (32 days after endovascular therapy) without recurrence of heart failure symptoms. This case highlights two clinically relevant points. First, endovascular therapy for aortoiliac occlusive disease led to improvement in heart failure status. Second, B type natriuretic peptide levels showed a clear improvement following endovascular therapy.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1595-1599"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Coronary Artery Dissection in a Young Women: A Case Report and Literature Review. 年轻女性自发性冠状动脉夹层1例报告及文献复习。
Jiong Xiao, Chaoyong He, Yiyan Wang, Ming Zhou
{"title":"Spontaneous Coronary Artery Dissection in a Young Women: A Case Report and Literature Review.","authors":"Jiong Xiao, Chaoyong He, Yiyan Wang, Ming Zhou","doi":"10.1002/ccd.70766","DOIUrl":"10.1002/ccd.70766","url":null,"abstract":"<p><p>Spontaneous coronary artery dissection (SCAD) is an infrequent etiology of acute coronary syndrome, characterized by its non-atherosclerotic, non-traumatic, and non-iatrogenic nature. SCAD involving the left main coronary artery (LMCA) constitutes an especially severe manifestation of this condition. This report details a complex and critical case of LMCA SCAD in a 38-year-old female patient who presented with chest pain, syncope, cardiogenic shock, severe hypokalemia, and electrocardiographic changes consistent with De Winter syndrome. Initial urgent coronary angiography (CAG) revealed LMCA stenosis of 40%-50%. Subsequent CAG, supplemented by intravascular ultrasound, demonstrated a progression of LMCA stenosis to 70%-80% and the presence of a diffuse intramural hematoma within the LMCA. Patients with LMCA SCAD are at a heightened risk for short-term complications. Therefore, prompt recognition and the implementation of appropriate management strategies are crucial.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1513-1519"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First-in-Human Use of a Novel Perfusion-Channel Drug-Coated Balloon to Manage Coronary Artery Perforation During Chronic Total Occlusion Intervention: A Case Report. 人类首次使用新型灌注通道药物包覆球囊治疗慢性全闭塞介入期间冠状动脉穿孔:一例报告。
Lingjun Zeng, Dongsheng Li
{"title":"First-in-Human Use of a Novel Perfusion-Channel Drug-Coated Balloon to Manage Coronary Artery Perforation During Chronic Total Occlusion Intervention: A Case Report.","authors":"Lingjun Zeng, Dongsheng Li","doi":"10.1002/ccd.70788","DOIUrl":"10.1002/ccd.70788","url":null,"abstract":"<p><p>Coronary artery perforation (CAP) remains a serious complication of percutaneous coronary intervention (PCI), with an increased incidence during chronic total occlusion (CTO) procedures. Conventional management using covered stents often compromises side branches and limits future revascularization options, while prolonged balloon inflation, though simpler, interrupts distal flow and increases ischemic risk. We present a case of a 54-year-old male with coronary heart disease, hypertension, and diabetes who underwent PCI for a severe proximal stenosis and a mid-segment CTO of the left anterior descending artery (LAD). Following small balloon predilation, an Ellis type II perforation occurred in the LAD main vessel region. A novel perfusion-channel drug-coated balloon (PcDCB) was immediately deployed, covering the proximal LAD and the ostium of a large diagonal branch (D1). Inflation at 6 atm for 10 minutes successfully sealed the perforation while maintaining TIMI 2 flow into D1 via its side channels. Post-procedural angiography and echocardiography confirmed complete sealing without pericardial effusion. This first-in-human experience demonstrates that the PcDCB can effectively manage CAP by achieving simultaneous mechanical sealing and distal perfusion, and in this case additionally treated a severely stenotic proximal segment, potentially avoiding stent implantation while preserving the option for future staged revascularization. The drug-coated property may offer added rationale for treating diseased segments, though its specific role in perforation management per se warrants further investigation.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1462-1466"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148674964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Failure Mode and Effects Analysis-Oriented Multidisciplinary Collaborative Nursing Model on Bleeding Prevention and Prognosis in Patients Undergoing Transradial Artery Coronary Angiography: A Randomized Controlled Trial. 以失效模式和效果分析为导向的多学科协同护理模式对经桡动脉冠状动脉造影患者出血预防和预后的影响:一项随机对照试验。
Lingxia Fan, Xiaoping Guo, Yanzhuo Ma, Wei Li
{"title":"Impact of Failure Mode and Effects Analysis-Oriented Multidisciplinary Collaborative Nursing Model on Bleeding Prevention and Prognosis in Patients Undergoing Transradial Artery Coronary Angiography: A Randomized Controlled Trial.","authors":"Lingxia Fan, Xiaoping Guo, Yanzhuo Ma, Wei Li","doi":"10.1002/ccd.70789","DOIUrl":"10.1002/ccd.70789","url":null,"abstract":"<p><strong>Background: </strong>Transradial artery coronary angiography (TRA) is widely used for coronary disease diagnosis, but postoperative puncture site bleeding (incidence: 3.1%-16.7%) remains a major clinical challenge. Fragmented care and poor multidisciplinary collaboration (MDC) contribute to this issue, while Failure Mode and Effects Analysis (FMEA)-a proactive risk tool-has not been integrated into MDC for TRA bleeding prevention.</p><p><strong>Aims: </strong>To evaluate the efficacy of an FMEA-oriented MDC nursing model on TRA postoperative bleeding, nursing efficiency, and patient outcomes.</p><p><strong>Methods: </strong>A single-center randomized controlled trial (RCT) enrolled 280 TRA patients (March 2024 to March 2025), randomized 1:1 to the experimental group (FMEA-oriented MDC care: joint assessment, standardized intraoperative collaboration, graded monitoring) or control group (conventional care).</p><p><strong>Primary outcome: </strong>24-h bleeding incidence (EAPCI criteria).</p><p><strong>Secondary outcomes: </strong>hemostasis time, length of hospital stay (LOS), healthcare provider-patient satisfaction, and psychological status (SAS/SDS).</p><p><strong>Results: </strong>The experimental group had lower 24-h bleeding incidence (4.3% vs. 13.6%, χ<sup>2</sup> = 7.832, p = 0.005), shorter hemostasis time (38.2 ± 8.5 vs. 54.6 ± 10.2 min, t = 13.264, p < 0.001) and LOS (3.1 ± 0.8 vs. 4.5 ± 1.2 days, t = 10.587, p < 0.001). Higher satisfaction scores (healthcare provider: 93.5 ± 4.2 vs. 77.8 ± 6.5; patient: 92.1 ± 3.8 vs. 80.5 ± 5.3; both p < 0.001) and lower postoperative SAS/SDS scores (both p < 0.001) were observed in the experimental group.</p><p><strong>Conclusion: </strong>The FMEA-oriented MDC model reduces TRA postoperative bleeding, improves nursing efficiency and satisfaction, and alleviates patient anxiety/depression, providing a standardized clinical solution.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1354-1365"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148633504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calcified Plaque Detachment: Alternative Calcified Plaque Modification After Coronary Intravascular Lithotripsy. 钙化斑块脱离:冠状动脉血管内碎石术后钙化斑块修饰的选择。
Daisuke Naito, Akiko Matsuo, Takeru Kasahara, Keisuke Ota, Shinsaku Matsunaga, Norio Nakajima
{"title":"Calcified Plaque Detachment: Alternative Calcified Plaque Modification After Coronary Intravascular Lithotripsy.","authors":"Daisuke Naito, Akiko Matsuo, Takeru Kasahara, Keisuke Ota, Shinsaku Matsunaga, Norio Nakajima","doi":"10.1002/ccd.70764","DOIUrl":"10.1002/ccd.70764","url":null,"abstract":"<p><strong>Background: </strong>Calcified plaque (CP) detachment (CD) and calcium fracture (CF) can occur following coronary intravascular lithotripsy (IVL). The extent to which CF alone facilitates stent expansion during CP modification with IVL remains unclear.</p><p><strong>Aims: </strong>This study aimed to investigate the clinical implications of IVL-induced CD.</p><p><strong>Methods: </strong>Optical coherence tomography was performed to assess coronary CP immediately after IVL in 45 consecutive patients for whom images were available. CD was defined as partial or complete separation of the CP from either the coronary artery intima or media. The study population was divided into CD and non-CD groups.</p><p><strong>Results: </strong>CD was observed in 22 patients (49%) without associated major dissection, intramural hematoma, or slow flow, whereas CF was observed in 35 patients (78%). No significant differences were found in baseline characteristics between the groups. The stent expansion index was not significantly different between the groups (77.6% vs. 83.2%, p = 0.17). Across increasing calcium arc grades, CD frequency decreased significantly (p = 0.01), whereas CF frequency increased (p = 0.02).</p><p><strong>Conclusions: </strong>CD frequently occurs in patients undergoing coronary IVL, with CP separation from the vessel wall proceeding safely and without coronary flow impairment. In addition to CF, CD may contribute to CP modification, facilitating lumen enlargement and successful stent deployment.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1279-1286"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13667323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148612203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SCORE-CUT: A Randomized Trial Comparison of Scoring, Cutting, and Non-Compliant Balloon Lesion Preparation Strategies for Drug-Coated Balloon Angioplasty-Rationale and Design. 评分-切割:药物包被球囊血管成形术中评分、切割和非依从性球囊病变准备策略的随机对照试验——理论基础和设计。
Chinmay Khandkar, Bharat Khialani, Jayant Ravindran, Pankaj Jain, Rahul Kurup, Avedis Ekmejian, George Touma, Claudia Cosgrove, Kal Asrress, Dinesh Selvakumar, Hisham Hallani, Kevin Liou, Tom Ford, Bernard Wong, Sarah Fairley, Scott Harding, Andy Yong, Cuneyt Ada
{"title":"SCORE-CUT: A Randomized Trial Comparison of Scoring, Cutting, and Non-Compliant Balloon Lesion Preparation Strategies for Drug-Coated Balloon Angioplasty-Rationale and Design.","authors":"Chinmay Khandkar, Bharat Khialani, Jayant Ravindran, Pankaj Jain, Rahul Kurup, Avedis Ekmejian, George Touma, Claudia Cosgrove, Kal Asrress, Dinesh Selvakumar, Hisham Hallani, Kevin Liou, Tom Ford, Bernard Wong, Sarah Fairley, Scott Harding, Andy Yong, Cuneyt Ada","doi":"10.1002/ccd.70787","DOIUrl":"10.1002/ccd.70787","url":null,"abstract":"<p><strong>Background: </strong>Drug-coated balloons (DCB) provide a \"metal-free\" alternative to drug-eluting stents, yet their success is highly dependent on optimal lesion preparation for effective drug transfer and to minimize acute recoil. While scoring balloons (SB) and cutting balloons (CB) are hypothesized to achieve superior plaque modification versus non-compliant balloons (NCBs) through controlled micro-dissections, high-quality randomized evidence in de-novo coronary lesions remains sparse.</p><p><strong>Aim: </strong>SCORE-CUT aims to determine the optimal lesion-preparation strategy prior to DCB angioplasty by directly comparing the efficacy of pre-dilation with NCB, SB, and CB.</p><p><strong>Methods: </strong>This is a prospective, multi-center, randomized trial conducted across sites in Australia, New Zealand, and Singapore (ACTRN12625001349437). A total of 198 patients with de-novo lesions (2.0-4.0 mm diameter on angiography) are randomized 1:1:1 to undergo lesion preparation with NCB, SB, or CB. Intravascular ultrasound (IVUS) imaging is performed both before and after lesion preparation. The primary endpoint is absolute minimum lumen area (MLA) gain (mm<sup>2</sup>) on IVUS after lesion preparation, analyzed by an independent, blinded core laboratory. Secondary endpoints include percentage MLA gain, frequency of flow-limiting dissections, and rates of bailout stenting. The study is powered to detect a 0.8 mm<sup>2</sup> difference in absolute MLA gain, with statistical significance at p < 0.05. Enrollment has commenced (n = 4) and the study is expected to complete enrollment by the end of 2026.</p><p><strong>Conclusions: </strong>SCORE-CUT is the first randomized trial to provide a head-to-head comparison of NCB, SB, and CB using IVUS-derived primary endpoints in de-novo disease. By utilizing intravascular imaging, the trial will provide robust evidence to standardize vessel preparation in DCB angioplasty.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1558-1563"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148725590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventional Mitral Valve Edge-to-Edge Repair in Patients Above 85 Years of Age. 85岁以上患者介入二尖瓣边缘到边缘修复。
Florian Jürgens, Florian Schindhelm, Mohammed Abusharekh, Jürgen Kampf, Matthias Totzeck, Fadi Al-Rashid, Peter Lüdike, Tienush Rassaf, Amir A Mahabadi
{"title":"Interventional Mitral Valve Edge-to-Edge Repair in Patients Above 85 Years of Age.","authors":"Florian Jürgens, Florian Schindhelm, Mohammed Abusharekh, Jürgen Kampf, Matthias Totzeck, Fadi Al-Rashid, Peter Lüdike, Tienush Rassaf, Amir A Mahabadi","doi":"10.1002/ccd.70807","DOIUrl":"10.1002/ccd.70807","url":null,"abstract":"<p><strong>Background: </strong>Mitral valve transcatheter-edge-to-edge repair (M-TEER) is routinely performed in patients with severe mitral regurgitation (MR) at high operative risk, frequently including elderly patients. Patients ≥ 85 years, however, are frequently excluded in clinical studies.</p><p><strong>Objectives: </strong>We evaluated differences of procedural characteristics and outcomes following M-TEER in patients < versus ≥ 85 years.</p><p><strong>Methods: </strong>We retrospectively included consecutive patients with severe MR who underwent M-TEER with the PASCAL device between 2019 and 2024 at our center. Baseline and procedural characteristics, short- and mid-term outcomes were compared, stratifying the cohort into patients < versus ≥ 85 years.</p><p><strong>Results: </strong>Three hundred seventy-five patients with moderate to severe or severe MR were eligible; 71 aged ≥ 85 (87.0 ± 1.7 years, 57.7% male) and 304 aged < 85 (75.5 ± 10.0 years, 58.6% male) years. Patients aged ≥ 85 years more frequently had severe MR (90.1% vs. 73.8%, p = 0.005) and higher STS-Score (6.4 [3.8; 9.1] vs. 3.5 [2.2; 6.5], p < 0.0001) at baseline. No leaflet injury, single leaflet detachment or any other device-related complication was observed, irrespective of age. Residual MR at 90 days was comparable among age groups (Trace: 34.8% vs. 23.8%; mild: 41.3% vs. 57.3%; moderate: 23.9% vs. 18.5%; moderate-severe: 0% vs. 0.4%, p = 0.56). Within 30 days, no death occurred in patients aged ≥ 85 years (one death in the < 85 years group). Median mid-term follow-up was 430 [164; 692] days. Overall mortality was not different for patients ≥ versus < 85 years (5.6% vs. 7.6%, p = 0.76).</p><p><strong>Conclusion: </strong>M-TEER is safe in patients ≥ 85 years, with procedural outcomes and mid-term prognosis similar to younger cohorts.</p>","PeriodicalId":520583,"journal":{"name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","volume":" ","pages":"1548-1557"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13667317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书