Applied biosafety : journal of the American Biological Safety Association最新文献

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Incorporating the Intent of the Experiment into Gain-of-Function Oversight. 将实验意图纳入功能获得监督。
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2025.0008
Michael J Imperiale
{"title":"Incorporating the Intent of the Experiment into Gain-of-Function Oversight.","authors":"Michael J Imperiale","doi":"10.1089/apb.2025.0008","DOIUrl":"10.1089/apb.2025.0008","url":null,"abstract":"<p><p>The U.S. government recently released a new policy for the oversight of research that could lead to the creation of pathogens with increased ability to cause an epidemic or pandemic. While this policy is generally well thought out, some of the criteria are somewhat subjective. I propose a new criterion with which to view these experiments.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"143-145"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Principal Investigator Responsibility for Flagging Research with Dual-Use or Pandemic Risk. 负责标记具有双重用途或大流行风险的研究的首席研究员。
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2024.0059
Marc Lipsitch
{"title":"Principal Investigator Responsibility for Flagging Research with Dual-Use or Pandemic Risk.","authors":"Marc Lipsitch","doi":"10.1089/apb.2024.0059","DOIUrl":"10.1089/apb.2024.0059","url":null,"abstract":"<p><p>The new United States Government Policy for Oversight of Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential places primary responsibility on the proposing principal investigator to flag potential need for special review. This approach may carry significant risks, given that investigators have incentives to downplay the types of risks the policy aims to address, compounded by substantial opposition to the policy from many virologists. However, this commentary argues that such an approach is much more consistent with proven models of research oversight for protecting human subjects and animals and may be essential in the long run. It identifies the need for several independent but potentially mutually reinforcing preconditions for success-which will require creativity and investment not fully specified in the regulations: researcher training on dual-use and population-level biosafety risks, effective institutional-level support for and scrutiny of investigator evaluation, cultural change, checks and balances, and speedy evaluation of low-risk research.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"139-142"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward a Collaborative, Collective, and Integrative International Chemical, Biological, Radiological, and Nuclear Security Education. 迈向协作、集体和综合的国际化学、生物、放射和核安全教育。
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2024.0048
Iris Magne, Olivia Ibbotson, Lijun Shang, Malcolm Dando
{"title":"Toward a Collaborative, Collective, and Integrative International Chemical, Biological, Radiological, and Nuclear Security Education.","authors":"Iris Magne, Olivia Ibbotson, Lijun Shang, Malcolm Dando","doi":"10.1089/apb.2024.0048","DOIUrl":"10.1089/apb.2024.0048","url":null,"abstract":"<p><strong>Background: </strong>Despite the entry into force of the 1975 Biological and Toxic Weapons Convention (BTWC) and the 1997 Chemical Weapons Convention (CWC) many years ago, the risk of malign use of chemistry and biology has been a consistently growing threat. Various initiatives have been proposed to address chemical, biological, radiological, and nuclear (CBRN) security issues, particularly on the issue of dual-use research of concern (DURC).</p><p><strong>Methods: </strong>In this article, we first briefly review the history and evolution of chemical and biological security education. Then we discuss the challenges faced among the initiatives developed to strengthen the BTWC and CWC. We further analyze the lessons learned for establishing global biosecurity education, and we conclude that international collaboration and coordination are keys to raising awareness of the necessity for biological security education. In the end, we detail our new initiative entitled the International Biological Security Education Network (IBSEN), which aims to provide this needed global framework through developing resources in biosecurity education in collaboration with international and regional actors using new methodologies and a linguistic plurality.</p><p><strong>Discussion: </strong>We believe that a collaborative, collective, and integrative international CBRN security education is the key to ensuring a broad engagement in biosecurity education and addressing the issue of DURC.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"167-173"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balancing Innovation and Safety: Frameworks and Considerations for the Governance of Dual-Use Research of Concern and Potential Pandemic Pathogens. 平衡创新和安全:关注和潜在大流行病原体两用研究的治理框架和考虑。
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2024.0033
David R Gillum
{"title":"Balancing Innovation and Safety: Frameworks and Considerations for the Governance of Dual-Use Research of Concern and Potential Pandemic Pathogens.","authors":"David R Gillum","doi":"10.1089/apb.2024.0033","DOIUrl":"10.1089/apb.2024.0033","url":null,"abstract":"<p><strong>Background: </strong>Governance of high-risk biological research, specifically dual-use research of concern (DURC) and pathogens with enhanced pandemic potential (PEPP), is a topic of renewed interest. This study considers the historical evolution of biosecurity policies, highlighting current challenges in balancing scientific progress with national security and public safety.</p><p><strong>Methods: </strong>A historical analysis and a literature review were conducted, examining significant events and policy developments shaping biosafety and biosecurity in the United States. The study also reviews possible frameworks for governing DURC and PEPP, assessing ethical, political, and regulatory perspectives from relevant literature.</p><p><strong>Results: </strong>Findings indicate that biosafety and biosecurity policies have historically been reactionary, responding to specific incidents rather than proactively managing risks. Despite significant policy efforts, gaps in transparency, oversight, and international collaboration persist, raising concerns about the effectiveness of governance structures. However, looking at past frameworks for managing high-risk biotechnological risks may be beneficial in establishing future governance strategies.</p><p><strong>Discussion: </strong>The study suggests the need for a balanced approach that integrates ethical, social, legal, and other considerations to ensure robust oversight of DURC and PEPP. Continuous policy evolution, informed by empirical evidence and interdisciplinary collaboration, is needed for mitigating risks associated with high-stakes biological research.</p><p><strong>Conclusion: </strong>Effective governance of DURC and PEPP requires comprehensive, interdisciplinary approaches that incorporate historical lessons, ethical considerations, and adaptive policymaking. Collaboration between policymakers, scientists, biosafety and biosecurity professionals, as well as members of the public, is required to ensure scientific innovation benefits national security and public health while minimizing risks.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"69-78"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12183502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unmet Expectations: Life Scientists' Views on Biorisk and Responsibility. 未满足的期望:生命科学家对生物风险和责任的看法。
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2024.0052
Daniel Greene, David A Relman, Megan J Palmer
{"title":"Unmet Expectations: Life Scientists' Views on Biorisk and Responsibility.","authors":"Daniel Greene, David A Relman, Megan J Palmer","doi":"10.1089/apb.2024.0052","DOIUrl":"10.1089/apb.2024.0052","url":null,"abstract":"<p><p>United States and global guidance documents and codes of conduct urge life scientists to practice a \"culture of responsibility\" by proactively managing the potential biosafety, biosecurity, and dual-use information risks of their work. However, research suggests that many life scientists are unfamiliar with or disengaged from aspects of biorisk management. To better understand life scientists' beliefs and attitudes about biorisk management, we conducted a survey with 127 researchers at a prestigious U.S. university who directly manipulate DNA or RNA in living organisms, cells, and/or viruses. We found that while participants were broadly positive about their efforts to address risks and expressed a sense of responsibility to do so, most failed to meet the expectations that they hold for how often a typical scientist in their research community should consider biosafety, biosecurity, or dual-use information risks. Faculty were more likely to meet their expectations than non-faculty, and all participants were more likely to meet their expectations considering biosafety risks compared with biosecurity or dual-use information risks. Most non-faculty said that they have \"never or almost never\" considered the risk of deliberate misuse or information release with their lab. Outside of mandatory biosafety training, few had received formal education about biorisks or discussed them at lab meetings. Career incentives and the logistical burdens of biorisk management were noted as reasons for disengagement. Our results suggest that by their own standards, U.S. life scientists have significant room for improvement in their capacity for proactive biorisk management, particularly regarding biosecurity and dual-use information risks.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"112-123"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution, New Concepts, and Institutional Adaptation to the 2024 Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential Policy. 2024年疫病与病原体军民两用研究的演变、新概念与制度适应
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2024.0035
Aline Dousse, Katharina Summermatter
{"title":"Evolution, New Concepts, and Institutional Adaptation to the 2024 Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential Policy.","authors":"Aline Dousse, Katharina Summermatter","doi":"10.1089/apb.2024.0035","DOIUrl":"10.1089/apb.2024.0035","url":null,"abstract":"","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"151-156"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What Does the Updated U.S. Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential Policy Mean for Asia? 美国军民两用研究的最新进展对亚洲意味着什么?
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.1089/apb.2024.0051
Poh Lian Lim
{"title":"What Does the Updated U.S. Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential Policy Mean for Asia?","authors":"Poh Lian Lim","doi":"10.1089/apb.2024.0051","DOIUrl":"10.1089/apb.2024.0051","url":null,"abstract":"<p><strong>Introduction: </strong>The U.S. government recently updated its policy for dual-use research of concern (DURC) and research involving pathogens with enhanced pandemic potential (PEPP). The policy comes into effect in May 2025.</p><p><strong>Methods: </strong>The U.S. policy covers the responsibilities for three major parties: principal investigators, research institutions, and Federal funding agencies. It outlines the criteria and provides examples of what constitutes Category 1 research (DURC) and Category 2 research (PEPP) and clarifies the process for developing and implementing risk mitigation plans. The relevance of this policy for research in Asia depends on local context and resources and its impact on changing biosecurity culture.</p><p><strong>Conclusion: </strong>This U.S. policy contributes substantially to the evolving international consensus that funders, research institutions, and researchers should implement enhanced oversight for DURC and PEPP. This is an important step forward for health security in Asia and globally.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":"30 2","pages":"174-177"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiences During the COVID-19 Pandemic: A Survey of Biosafety Professionals. COVID-19大流行期间的经验:对生物安全专业人员的调查。
IF 1.5
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2022-09-01 Epub Date: 2022-09-14 DOI: 10.1089/apb.2022.0012
David Gillum, Henry Wyneken, Jennifer Fletcher, Karl Nubbe, Kathleen M Vogel
{"title":"Experiences During the COVID-19 Pandemic: A Survey of Biosafety Professionals.","authors":"David Gillum,&nbsp;Henry Wyneken,&nbsp;Jennifer Fletcher,&nbsp;Karl Nubbe,&nbsp;Kathleen M Vogel","doi":"10.1089/apb.2022.0012","DOIUrl":"https://doi.org/10.1089/apb.2022.0012","url":null,"abstract":"<p><strong>Introduction: </strong>Biosafety professionals were called to action during the COVID-19 pandemic. They were tasked with prescribing measures to keep workers and the community safe while often not having accurate information at their fingertips. Understanding biosafety professionals' experiences may help shape new approaches that could further advance preparedness and resilience goals for future pandemics. This article discusses the overall response efforts of the biosafety community.</p><p><strong>Objectives: </strong>The main objective of this article is to quantitatively and qualitatively interrogate the responses to an email survey sent to individuals with biosafety responsibilities during the COVID-19 pandemic. This article catalogues those responses and the different aspects in how biosafety professionals were involved in the pandemic. The focus of this research was on aggregate data and summarized results.</p><p><strong>Results: </strong>A total of 609 out of 654 respondents fully completed the survey, equating to a 93.1% completion rate. Respondents were individuals with varying levels of COVID-19-related responsibilities participating in emergency preparedness and planning, developing laboratory diagnostic capabilities, reviewing clinical trials, developing safety guidelines, writing return-to-work and quarantine procedures, and participating in press releases and communications.</p><p><strong>Conclusions: </strong>Biosafety professionals played important roles during the COVID-19 pandemic, from developing safety protocols for laboratories to resourcing personal protective equipment during a global shortage. They experienced challenges when balancing their home/work lives. Some biosafety professionals were very involved in clinical trials and vaccination efforts, but most were not. Overall, there were significant differences in how biosafety professionals were involved in pandemic response efforts.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":" ","pages":"127-143"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33487714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Biosafety Practices When Working with Bats: A Guide to Field Research Considerations. 与蝙蝠一起工作时的生物安全实践:实地研究注意事项指南。
IF 1.5
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2022-09-01 Epub Date: 2022-09-14 DOI: 10.1089/apb.2022.0019
Alvaro Aguilar-Setién, Nidia Aréchiga-Ceballos, Gary A Balsamo, Amy J Behrman, Hannah K Frank, Gary R Fujimoto, Elizabeth Gilman Duane, Thomas Warner Hudson, Shelley M Jones, Luis A Ochoa Carrera, Gregory L Powell, Carrie A Smith, Joni Triantis Van Sickle, Susan E Vleck
{"title":"Biosafety Practices When Working with Bats: A Guide to Field Research Considerations.","authors":"Alvaro Aguilar-Setién,&nbsp;Nidia Aréchiga-Ceballos,&nbsp;Gary A Balsamo,&nbsp;Amy J Behrman,&nbsp;Hannah K Frank,&nbsp;Gary R Fujimoto,&nbsp;Elizabeth Gilman Duane,&nbsp;Thomas Warner Hudson,&nbsp;Shelley M Jones,&nbsp;Luis A Ochoa Carrera,&nbsp;Gregory L Powell,&nbsp;Carrie A Smith,&nbsp;Joni Triantis Van Sickle,&nbsp;Susan E Vleck","doi":"10.1089/apb.2022.0019","DOIUrl":"https://doi.org/10.1089/apb.2022.0019","url":null,"abstract":"<p><strong>Introduction: </strong>Field work with bats is an important contribution to many areas of research in environmental biology and ecology, as well as microbiology. Work with bats poses hazards such as bites and scratches, and the potential for exposure to infectious pathogens such as rabies virus. It also exposes researchers to many other potential hazards inherent to field work, such as environmental conditions, delayed emergency responses, or challenging work conditions.</p><p><strong>Methods: </strong>This article discusses the considerations for a thorough risk assessment process around field work with bats, pre- and post-occupational health considerations, and delves into specific considerations for areas related to biosafety concerns-training, personal protective equipment, safety consideration in field methods, decontamination, and waste. It also touches on related legal and ethical issues that sit outside the realm of biosafety, but which must be addressed during the planning process.</p><p><strong>Discussion: </strong>Although the focal point of this article is bat field work located in northern and central America, the principles and practices discussed here are applicable to bat work elsewhere, as well as to field work with other animal species, and should promote careful considerations of how to safely conduct field work to protect both researchers and animals.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":" ","pages":"169-190"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b5/cb/apb.2022.0019.PMC9526472.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33487716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbial Aerosols Generated from Standard Microbiological Laboratory Procedures. 微生物气溶胶产生的标准微生物实验室程序。
Applied biosafety : journal of the American Biological Safety Association Pub Date : 2022-06-01 Epub Date: 2022-05-27 DOI: 10.1089/apb.2021.0038
Thomas Pottage, Didier Ngabo, Simon Parks, Helen Hookway, Neville Q Verlander, Kazunobu Kojima, Allan M Bennett
{"title":"Microbial Aerosols Generated from Standard Microbiological Laboratory Procedures.","authors":"Thomas Pottage, Didier Ngabo, Simon Parks, Helen Hookway, Neville Q Verlander, Kazunobu Kojima, Allan M Bennett","doi":"10.1089/apb.2021.0038","DOIUrl":"10.1089/apb.2021.0038","url":null,"abstract":"<p><strong>Background: </strong>Modern microbiology laboratories are designed to protect workers and the environment from microbial aerosols produced during microbiological procedures and accidents. However, there is only limited data available on the aerosols generated from common microbiology procedures.</p><p><strong>Methods: </strong>A series of common microbiological procedures were undertaken with high concentration spore suspensions while air samplers were operated to sample the aerosols generated. Surface contamination from droplets was visualized using sodium fluorescein within the suspension. A total of 36 procedures were studied using different sample volumes (0.1-10 mL) and two spore suspension titers (10<sup>7</sup> and 10<sup>9</sup> colony forming units [cfu]/mL).</p><p><strong>Results: </strong>The aerosol concentrations generated varied from 0 to 13,000 cfu/m<sup>3</sup>. There was evidence to suggest that titer, volume, and poor use of equipment were significant factors in increased aerosol generation from some of the procedures. A risk assessment undertaken using the data showed that any aerosol generated from these processes would be contained within a correctly operating biological safety cabinet. Therefore, with these procedures, the operator and the environment would not require any additional protective measures such as respiratory protective equipment or a negative pressure laboratory to prevent aerosol exposure or release.</p><p><strong>Conclusions: </strong>Aerosol generation from common laboratory processes can be minimized by reducing sample volumes and concentrations if possible. Training laboratory staff in good microbiological techniques would further mitigate aerosols generated from common laboratory processes.</p>","PeriodicalId":520561,"journal":{"name":"Applied biosafety : journal of the American Biological Safety Association","volume":" ","pages":"92-99"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33444801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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