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Effects of an early childhood father engagement program in Rohingya camps and host community in Cox's Bazar, Bangladesh: a cluster randomized controlled trial. 孟加拉国考克斯巴扎尔罗兴亚难民营和收容社区的早期儿童父亲参与项目的影响:一项随机对照试验。
BMC global and public health Pub Date : 2026-04-09 DOI: 10.1186/s44263-026-00266-x
Yeshim Iqbal, Hirokazu Yoshikawa, Duja Michael, Sneha Bolisetty, Sakila Yesmin, Ashraf Uddin Mian, Maung Ting Nyeu, Sangyoo Lee, A Brooks Bowden, Kate Schwartz, Kuri Chisim, A R M Mehrab Ali, Sadia Sumaia Chowdhury, Anika Alam, Jere R Behrman
{"title":"Effects of an early childhood father engagement program in Rohingya camps and host community in Cox's Bazar, Bangladesh: a cluster randomized controlled trial.","authors":"Yeshim Iqbal, Hirokazu Yoshikawa, Duja Michael, Sneha Bolisetty, Sakila Yesmin, Ashraf Uddin Mian, Maung Ting Nyeu, Sangyoo Lee, A Brooks Bowden, Kate Schwartz, Kuri Chisim, A R M Mehrab Ali, Sadia Sumaia Chowdhury, Anika Alam, Jere R Behrman","doi":"10.1186/s44263-026-00266-x","DOIUrl":"10.1186/s44263-026-00266-x","url":null,"abstract":"<p><strong>Background: </strong>This study evaluates a 6-month early childhood father engagement intervention delivered in-person to fathers in the Rohingya camps and surrounding host communities in Cox's Bazar, Bangladesh. The intervention is an added component to an existing intervention that works with mothers of 0-3-year-old children to improve positive outcomes of child development and targets fathers with children below 3 years, with objectives to promote fathers' wellbeing by improving their emotional literacy, encouraging fathers to strengthen relationships with their spouses and children, and encouraging responsive and stimulating caregiving practices among fathers.</p><p><strong>Methods: </strong>We used a cluster-randomized controlled trial design (total N = 2002 fathers, 786 in the Rohingya camps and 1216 in the host communities) to assess the impact of the program on fathers' parenting and engagement with family (reported by both fathers and mothers), fathers' mental health, and child development.</p><p><strong>Results: </strong>We find that the program has a positive impact on the fathers' parenting (father reported) and engagement with family (father and mother reported), as well as on father-reported child social-emotional development, compared to the mother-only program. While the program did not have a main effect on directly assessed child development outcomes, we do find that baseline mother-reported stimulation with child and mother health moderate the impact on father-reported child social-emotional development in the camp community (larger positive impacts for fathers from households with lower baseline mother-reported stimulating behaviors and health). We also find that child gender and mother-reported stimulating behaviors moderate impacts on multiple mother-reported child developmental outcomes in both host and camp communities (treatment effects on these outcomes were negative for boys and positive but weak for girls, and larger positive impacts on mother-reported motor development were found among mothers from households who reported lower stimulation at baseline). Additionally, child age moderates the impact on fathers' collaboration with the mother (reported by the mother), such that the treatment effect is larger for mothers of older children.</p><p><strong>Conclusions: </strong>Our findings demonstrate the potential of father-focused programs as powerful caregiver interventions.</p><p><strong>Trial registration: </strong>Pre-registered with REES (13880.1v2); retrospectively registered at ISRCTN (ISRCTN13510859).</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13067743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147648131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing multimorbidity and the risk for hospitalization among people living with HIV from the African Cohort Study. 非洲队列研究中艾滋病毒感染者的多发病特征和住院风险
BMC global and public health Pub Date : 2026-04-08 DOI: 10.1186/s44263-026-00260-3
Remle Scott, Cara H Olsen, Trevor A Crowell, James D Mancuso, Hannah Kibuuka, Jonah Maswai, John Owuoth, Valentine Sing'oei, Emmanuel Bahemana, Zahra Parker, Julie A Ake, Neha Shah, Elizabeth H Lee
{"title":"Characterizing multimorbidity and the risk for hospitalization among people living with HIV from the African Cohort Study.","authors":"Remle Scott, Cara H Olsen, Trevor A Crowell, James D Mancuso, Hannah Kibuuka, Jonah Maswai, John Owuoth, Valentine Sing'oei, Emmanuel Bahemana, Zahra Parker, Julie A Ake, Neha Shah, Elizabeth H Lee","doi":"10.1186/s44263-026-00260-3","DOIUrl":"10.1186/s44263-026-00260-3","url":null,"abstract":"<p><strong>Background: </strong>Multimorbidity presents significant challenges for people living with HIV (PLWH) in sub-Saharan Africa given the dual burden of communicable and noncommunicable diseases. We aimed to characterize multimorbidity and examine its association with hospitalization among PLWH.</p><p><strong>Methods: </strong>The African Cohort Study (AFRICOS) prospectively enrolls participants aged ≥ 15 years with and without HIV at 12 sites in Kenya, Tanzania, Uganda, and Nigeria. Our analyses were restricted to PLWH and ≥ 18 years of age at enrollment between February 2013 and May 2024. Multimorbidity, defined as the presence of two or more chronic conditions in addition to HIV, was ascertained through International Classification of Diseases version 10 codes on medical history documentation at study enrollment. Hospitalization was ascertained through case reporting forms. Hierarchical clustering was used to describe multimorbidity, and logistic regression reporting adjusted odds ratios (aOR) and 95% confidence intervals (CI) was used to evaluate the association between multimorbidity and hospitalization.</p><p><strong>Results: </strong>Of 3199 PLWH, 1863 (58.2%) were women, and the median age was 37.3 years (interquartile range: 29.2-45.5). Multimorbidity prevalence was 12.4%. Anemia (8.3%), head-related disorders (7.3%), and neuropathy (6.6%) were most common. Hierarchical clustering identified gastrointestinal (n = 80) and neuropathy (n = 212) first. The hospitalization rate was 4.32 hospitalizations per 100 person-years. Multimorbidity was associated with increased hospitalization (aOR = 1.44; 95% CI, 1.06, 1.96) after adjusting for age, sex, country, antiretroviral therapy (ART) regimen, and viral suppression.</p><p><strong>Conclusions: </strong>Multimorbidity was relatively uncommon at enrollment among PLWH in AFRICOS; however, distinct comorbidity patterns-such as gastrointestinal conditions and neuropathy-highlight the need for integrated, context-specific care. Multimorbidity was associated with a higher risk for hospitalization, while factors such as age, ART regimen, and viral suppression point to key intervention targets. These findings emphasize the importance of monitoring multimorbidity over time and adapting HIV care models to address the emerging chronic disease burden.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accelerating tuberculosis diagnosis in Mozambican prisons using digital chest X-rays with computer-aided detection: a longitudinal, comprehensive health intervention. 利用计算机辅助检测的数字胸部x光加速莫桑比克监狱的结核病诊断:一项纵向、全面的卫生干预措施。
BMC global and public health Pub Date : 2026-04-03 DOI: 10.1186/s44263-026-00256-z
Amadin A Olotu, Justy Antony Chiramal, Rachel A Boehm, Aswathy M Nair, Sanya Chawla, Mário A Vicente, Dulcidio A Matusse, Sérgio T Uate, Amândio S Munguambe, Edwin J Prophete, Victoria M Brown, Cremilde M Anli, Shibu Vijayan, Ivan R Calder, Anne C Spaulding
{"title":"Accelerating tuberculosis diagnosis in Mozambican prisons using digital chest X-rays with computer-aided detection: a longitudinal, comprehensive health intervention.","authors":"Amadin A Olotu, Justy Antony Chiramal, Rachel A Boehm, Aswathy M Nair, Sanya Chawla, Mário A Vicente, Dulcidio A Matusse, Sérgio T Uate, Amândio S Munguambe, Edwin J Prophete, Victoria M Brown, Cremilde M Anli, Shibu Vijayan, Ivan R Calder, Anne C Spaulding","doi":"10.1186/s44263-026-00256-z","DOIUrl":"10.1186/s44263-026-00256-z","url":null,"abstract":"<p><strong>Background: </strong>Mozambique has a high burden of tuberculosis (TB) and in 2021, an estimated 18,000 persons with TB nationwide were not diagnosed. Estimates suggest that globally 47% of TB disease in prisons is undiagnosed. We implemented an integrated-care model health intervention to enhance the diagnosis and treatment of TB disease, provide TB preventive treatment (TPT), and identify and treat other undiagnosed health conditions in three prisons in Maputo, Mozambique.</p><p><strong>Methods: </strong>From July 11, 2023, through the second quarter of 2024, we systematically screened for TB using digital chest X-rays with computer-aided detection (DCXR-CAD). This was combined with symptom screening in a parallel algorithm. We conducted clinical assessments for other health conditions and delivered TPT. Graphs visually compare TB case notification trends with two control prisons, which continued the usual standard of care, symptom screening for TB. An interrupted time series (ITS) analysis was used to evaluate TB case notification counts before and after the intervention in the intervention prisons.</p><p><strong>Results: </strong>Of 7912 individuals screened, 264 new diagnoses of TB disease were notified, a TB screening yield of 3.34% and a number needed to screen of 30, and 1346 persons were initiated on TPT. Other conditions diagnosed and treated include HIV (28), malnutrition (830), and skin conditions (462). TB case notifications were higher in the intervention prisons during the intervention than in the preceding period in the same prisons. Comparing case notifications during the intervention with an equivalent period prior to the intervention showed an increase of about 52% in intervention prisons but a decrease in control prisons by the same magnitude. The ITS analysis found the effect of the intervention on TB case notification counts statistically significant in two of the intervention prisons: (incidence rate ratio [IRR] 3.96, 95% confidence interval [CI] 1.51-10.40; p = 0.005) and (IRR 6.17, 95% CI 2.17-17.55; p < 0.001).</p><p><strong>Conclusions: </strong>Strengthening local infrastructure and implementing DCXR-CAD for screening likely contributed to a higher TB yield in the intervention prisons. Screening and diagnosing TB, delivering TB disease treatment and prevention, and addressing other health conditions simultaneously in this vulnerable population were feasible and important.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family first: integrating principles of family-centered care to improve the tuberculosis care cascade. 家庭第一:整合以家庭为中心的护理原则,改善结核病护理梯级。
BMC global and public health Pub Date : 2026-03-26 DOI: 10.1186/s44263-026-00264-z
Meredith B Brooks, Ashlee Vance, Nirupa Misra, Leonid Lecca, Maria Jaswal, Suchitra N Goodwin, Brittney J van de Water
{"title":"Family first: integrating principles of family-centered care to improve the tuberculosis care cascade.","authors":"Meredith B Brooks, Ashlee Vance, Nirupa Misra, Leonid Lecca, Maria Jaswal, Suchitra N Goodwin, Brittney J van de Water","doi":"10.1186/s44263-026-00264-z","DOIUrl":"10.1186/s44263-026-00264-z","url":null,"abstract":"<p><p>Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide, with persistent losses across the care cascade from screening and diagnosis to treatment completion and prevention. While TB programs have largely focused on disease control and individual patients, many barriers to care arise at the household level, including stigma, financial strain, caregiving demands, and limited access to information and support. Family-centered care (FCC), which engages families as active partners through shared decision-making, respect, and tailored support, has improved outcomes in other health areas but has not been systematically applied to TB. Here, we argue that integrating FCC into TB care can reduce losses across the cascade and improve outcomes for individuals and households. FCC offers a unifying framework to strengthen engagement, equity, and continuity of care. It can address key barriers by promoting tailored education, shared treatment planning, household involvement, and coordinated social, economic, and clinical supports across prevention, diagnosis, treatment, and follow-up. Drawing on existing evidence and case vignettes, we outline practical strategies to align FCC principles with TB program activities. We also highlight key considerations for implementation, including workforce training, community partnerships, resource needs, and potential trade-offs such as caregiver burden or unintended stigma, underscoring the importance of context-specific adaptation. Adopting a family-centered approach provides a pragmatic pathway to strengthen TB programs, enhance patient and household experiences, and accelerate progress toward TB elimination.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13020358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The 100 Days Mission: a perspective on accelerating vaccine manufacturing for future pandemics. 100天使命:从加速疫苗生产的角度看未来的大流行。
BMC global and public health Pub Date : 2026-03-20 DOI: 10.1186/s44263-026-00262-1
B Adam Williams, P Michelle Fitzsimmons, Lavinia M Lewis, James Tornos, Luke Kimmel, Jane M True, Pamela J Siwik, Martina Ryall, Kilian Mullett
{"title":"The 100 Days Mission: a perspective on accelerating vaccine manufacturing for future pandemics.","authors":"B Adam Williams, P Michelle Fitzsimmons, Lavinia M Lewis, James Tornos, Luke Kimmel, Jane M True, Pamela J Siwik, Martina Ryall, Kilian Mullett","doi":"10.1186/s44263-026-00262-1","DOIUrl":"10.1186/s44263-026-00262-1","url":null,"abstract":"<p><p>The \"100 Days Mission\" aims to compress the timeline for delivering safe and effective vaccines in response to future pandemics. Here, we present insights from Pfizer leaders involved in the COVID-19 vaccine effort on key enablers for rapid large-scale manufacture of pandemic vaccines to achieve this ambitious goal. For pharmaceutical companies, these enablers include robust governance models, secure supply chains, innovative production strategies, and maintained \"warm\" manufacturing capacity. Additionally, we examine the crucial role of government support through regulatory harmonization, enhanced global surveillance, and improved logistics. By addressing these critical factors, the global community can better prepare for rapid vaccine manufacturing in response to future pandemic threats.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13003682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reciprocal innovation in implementation science and global health: reflections from the EXTRA-CVD (extending the HIV treatment cascade for cardiovascular disease prevention) study. 实施科学和全球健康的相互创新:来自EXTRA-CVD(扩展艾滋病毒治疗级联以预防心血管疾病)研究的反思。
BMC global and public health Pub Date : 2026-03-18 DOI: 10.1186/s44263-026-00257-y
Claudia L Leung, Hayden B Bosworth, Allison R Webel, Angela Aifah, Constantine Akwanalo, Gerald S Bloomfield, Emily W Choi, Barbara M Gripshover, Corrilynn O Hileman, Jemima Kamano, Virginie Lopez-Kidwell, Charles Muiruri, Benson Njuguna, Nwora Lance Okeke, Christopher T Longenecker, Rajesh Vedanthan
{"title":"Reciprocal innovation in implementation science and global health: reflections from the EXTRA-CVD (extending the HIV treatment cascade for cardiovascular disease prevention) study.","authors":"Claudia L Leung, Hayden B Bosworth, Allison R Webel, Angela Aifah, Constantine Akwanalo, Gerald S Bloomfield, Emily W Choi, Barbara M Gripshover, Corrilynn O Hileman, Jemima Kamano, Virginie Lopez-Kidwell, Charles Muiruri, Benson Njuguna, Nwora Lance Okeke, Christopher T Longenecker, Rajesh Vedanthan","doi":"10.1186/s44263-026-00257-y","DOIUrl":"10.1186/s44263-026-00257-y","url":null,"abstract":"<p><p>Reciprocal innovation, a model of sustained, multidirectional exchange in which health strategies are adapted, revisited, and refined across contexts, offers a compelling framework to rethink how implementation science can support global health equity by enabling dynamic, multidirectional learning across different contexts. Drawing on the EXTRA-CVD trial, a nurse-led cardiovascular disease prevention intervention designed to extend the HIV treatment cascade in United States (U.S.) HIV clinics, which adapted strategies informed by implementation research in Kenya and the U.S. Veterans Affairs health system, this perspective examines how reciprocal innovation can begin to emerge within existing research structures, as well as where opportunities for deeper exchange remain limited. We identify four operational domains of reciprocal innovation: care delivery strategies, end-user engagement, research methodologies, and research leadership and partnership. Across these domains, we describe how cross-context learning shaped intervention adaptation and site-level implementation in EXTRA-CVD, as well as missed opportunities where more intentional feedback, shared leadership, and methodological exchange could have strengthened multidirectional learning. Taken together, this work highlights both the potential and the practical challenges of reciprocal innovation in implementation research, emphasizing its role in moving beyond unidirectional knowledge transfer toward iterative, context-responsive learning. By embedding structures for iterative feedback, equity-centered governance, and multidirectional learning systems within research and implementation systems, future global partnerships can foster more inclusive, responsive, and sustainable health interventions.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12998207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New frontiers for unmanned aerial vehicles in planetary health research. 无人驾驶飞行器在行星健康研究中的新领域。
BMC global and public health Pub Date : 2026-03-13 DOI: 10.1186/s44263-026-00250-5
Juliet T Bramante, Morgan S Tarpenning, Katherine E Woo, Andrew J Chamberlin, Kavita D Coombe, Joelle I Rosser
{"title":"New frontiers for unmanned aerial vehicles in planetary health research.","authors":"Juliet T Bramante, Morgan S Tarpenning, Katherine E Woo, Andrew J Chamberlin, Kavita D Coombe, Joelle I Rosser","doi":"10.1186/s44263-026-00250-5","DOIUrl":"10.1186/s44263-026-00250-5","url":null,"abstract":"<p><p>Unmanned aerial vehicles (UAVs) are a revolutionary new surveillance and transport technology with important implications for healthcare systems, particularly in the era of climate change. Rapid shifts in environmental systems are reshaping global climates. These changes have led to increasingly common extreme weather events that threaten population health. Mitigating the impacts of climate change on human health depends on our ability to predict, detect, and rapidly respond to changing ecosystem dynamics. The use of UAVs to tackle these new environmental health challenges is gaining momentum across multiple disciplines. This review identified four main areas where UAVs are being used or piloted to address climate change and health-related concerns: (1) Disease vector management, (2) environmental risk factors management, (3) environmental resource management, and (4) medical deliveries. Over the coming decades, UAVs are likely to play an increasing role in our efforts to keep pace with monitoring and mitigating the accelerating impacts of climate change on human health.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12983850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life among people with tuberculosis in the Eastern Cape, South Africa: a qualitative study. 南非东开普省肺结核患者的生活质量:一项定性研究。
BMC global and public health Pub Date : 2026-03-12 DOI: 10.1186/s44263-026-00258-x
Nancy Bedingfield, Kuhle Fiphaza, Mahilet Girma, Liyabuya Majiza, Lindsey De Vos, Dawie Olivier, Aaron M Kipp, Andrew Medina-Marino, Amrita Daftary
{"title":"Quality of life among people with tuberculosis in the Eastern Cape, South Africa: a qualitative study.","authors":"Nancy Bedingfield, Kuhle Fiphaza, Mahilet Girma, Liyabuya Majiza, Lindsey De Vos, Dawie Olivier, Aaron M Kipp, Andrew Medina-Marino, Amrita Daftary","doi":"10.1186/s44263-026-00258-x","DOIUrl":"10.1186/s44263-026-00258-x","url":null,"abstract":"<p><strong>Background: </strong>Quality of life (QoL) for people affected by tuberculosis (TB) is generally poor. However, little is known about when and why it changes during treatment. Such knowledge is key to the development and implementation of meaningful interventions. We sought to explore perceptions of QoL amongst people with pulmonary TB during and after treatment.</p><p><strong>Methods: </strong>This study was embedded within a larger study exploring multilevel determinants on TB cascade-of-care outcomes in Eastern Cape, South Africa. Between November 2023 and April 2024, 33 adults were purposively sampled for individual semi-structured interviews early, mid, and at the conclusion of treatment. Questions explored perspectives on current QoL and changes in specific domains (e.g., role functioning, mental wellbeing) during illness and treatment. Inductive and deductive techniques were combined in thematic analysis which incorporated QoL and chronic illness frameworks.</p><p><strong>Results: </strong>Participants described a common trajectory in QoL changes; however, overall assessments of QoL were highly personal. Shared trajectory was characterized by four phases: 'progressive disability to diagnosis', 'treatment challenges and QoL bottom', 'inflection and hope', and 'stability and incomplete resolution'. TB symptoms limited functional mobility, causing a financial crisis for many. Intense need for caregiving, emotional, and financial support persisted for weeks and months until physical gains eased problems in other domains. However, many who had completed treatment described continued weakness and inability to work. Participants provided highly varied assessments of current QoL rooted in personal priorities and individual circumstances. While few clear trends were noted, those with recurrent TB (48%, n = 16) were more often dissatisfied with their wellbeing. By the end of treatment, participants were no more likely to evaluate QoL positively compared to those earlier in treatment.</p><p><strong>Conclusions: </strong>Adaptable interventions that can be tailored to individual needs are required to help those with TB feel good about their life position. Intervention components should be delivered in the setting of long-term relationships with providers and prioritize financial wellbeing and counselling. High levels of support are needed during early treatment but supports must remain accessible through treatment completion and beyond.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12980979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depression, anxiety, and post-traumatic stress disorder in pregnancies among Métis people in Alberta: a population-based cross-sectional study. 抑郁症、焦虑症和创伤后应激障碍孕妇在艾伯塔省:一项基于人群的横断面研究。
BMC global and public health Pub Date : 2026-03-11 DOI: 10.1186/s44263-026-00259-w
Sawayra Owais, Jesus Serrano-Lomelin, Reagan Bartel, Kelsey Bradburn, Ryan J Van Lieshout, Maria B Ospina
{"title":"Depression, anxiety, and post-traumatic stress disorder in pregnancies among Métis people in Alberta: a population-based cross-sectional study.","authors":"Sawayra Owais, Jesus Serrano-Lomelin, Reagan Bartel, Kelsey Bradburn, Ryan J Van Lieshout, Maria B Ospina","doi":"10.1186/s44263-026-00259-w","DOIUrl":"10.1186/s44263-026-00259-w","url":null,"abstract":"<p><strong>Background: </strong>Despite high stress from historical trauma, systemic discrimination, and limited access to culturally-safe healthcare, the perinatal mental health of the Métis, Canada's second-largest Indigenous group, remains poorly understood. We evaluated the prevalence and sociodemographic and clinical factors associated with depression, anxiety, and post-traumatic stress disorder (PTSD) in Métis pregnancies.</p><p><strong>Methods: </strong>This cross-sectional study used population-based retrospective cohort data of all pregnancies resulting in live births (≥ 22 weeks' gestation) in Alberta, Canada, from 2006 to 2016. The Métis cohort was identified through linkage between the Identification Registry of the Otipemisiwak Métis Government of the Métis Nation within Alberta and administrative health databases. Diagnoses of depression, anxiety, and PTSD were identified in administrative health databases using validated case-finding algorithms. Age-standardized prevalence of depression, anxiety, and PTSD were compared between Métis and non-Métis pregnancies. Multilevel, multivariable Poisson regression models examined sociodemographic and clinical factors associated with these conditions in Métis pregnancies. Adjusted prevalence ratios (aPR) with 95% confidence intervals (CI) were reported, adjusting for relevant sociodemographic and clinical characteristics.</p><p><strong>Results: </strong>The study analyzed 8,163 Métis and 487,294 non-Métis pregnancies. The age-adjusted prevalence of depression in Métis pregnancies was 3.3% (95% CI 2.7, 3.9), while the prevalence of anxiety was 3.5% (95% CI 2.9, 4.2). Depression was 1.44 times (95% CI 1.25, 1.64) and anxiety 1.31 times (95%CI 1.15, 1.49) more prevalent in Métis than non-Métis pregnancies. PTSD prevalence was low in both groups. Among Métis pregnancies, urban residence, pre-existing medical conditions, and smoke or substance use in pregnancy were associated with higher depression and anxiety prevalence.</p><p><strong>Conclusions: </strong>Depression and anxiety during pregnancy were more common in Métis than non-Métis pregnancies. Collaboration with Métis organizations is critical to developing culturally-relevant detection and treatment for mental health challenges.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12977609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Promoting migrant health as a universal right in the United Kingdom. 促进移徙者健康作为联合王国的一项普遍权利。
BMC global and public health Pub Date : 2026-03-02 DOI: 10.1186/s44263-026-00254-1
Luisa Silva, Rebecca F Baggaley, Mayuri Gogoi, Paul Bird, Daniel Pan, Anna Miller, Chloe Freeman, Ellana Slade, Laura B Nellums, Manish Pareek
{"title":"Promoting migrant health as a universal right in the United Kingdom.","authors":"Luisa Silva, Rebecca F Baggaley, Mayuri Gogoi, Paul Bird, Daniel Pan, Anna Miller, Chloe Freeman, Ellana Slade, Laura B Nellums, Manish Pareek","doi":"10.1186/s44263-026-00254-1","DOIUrl":"10.1186/s44263-026-00254-1","url":null,"abstract":"<p><p>Migrants arriving in the United Kingdom (UK), many of whom experience vulnerability before and during migration, face a double burden of communicable and non-communicable diseases shaped by cumulative exposures in their countries of origin, across the migration journey, and compounded by fragmented access to care upon arrival. Despite improvements in pre-entry health assessments, post-arrival provision in reception centres remains inconsistent, with significant gaps in infectious disease screening, mental health support, medication continuity, and timely registration with a general practitioner (GP). Community-led initiatives like Doctors of the World's Safe Surgeries and the Oxford Refugee Health Initiative promote inclusive healthcare access, yet remain limited in scale. Using a social determinants of health (SDH) lens, this perspective highlights how structural barriers-including overcrowded accommodation, language challenges, and unclear entitlements-undermine the effectiveness of existing health policies and widen inequalities. We propose an essential care package for UK migrant reception centres that integrates early screening, stable access to medicines, mental health assessment, environmental health measures, and robust continuity of care for non-communicable diseases through clear referral pathways into the National Health Service (NHS). Embedding this approach within current public health infrastructure would reduce preventable morbidity, strengthen health system efficiency, and advance the UK's commitment to Sustainable Development Goals. Strengthening care at the point of arrival is therefore critical to promoting health equity and ensuring that no one is left behind.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12952055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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