The National medical journal of India最新文献_第2页

Medical education in Hindi and indigenous languages in India: Issues and challenges. 印度印地语和土著语言医学教育：问题与挑战。

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_983_2022

Rajesh Garg

引用次数: 0

The association between Behçet disease activity and elevated systemic immune-inflammation index: A retrospective observational study in a tertiary care hospital. 贝赫切特病活动性与全身免疫炎症指数升高之间的关联：一家三级医院的回顾性观察研究。

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_212_2022

Dilek Mentesoglu, Nilgün Atakan

{"title":"The association between Behçet disease activity and elevated systemic immune-inflammation index: A retrospective observational study in a tertiary care hospital.","authors":"Dilek Mentesoglu, Nilgün Atakan","doi":"10.25259/NMJI_212_2022","DOIUrl":"10.25259/NMJI_212_2022","url":null,"abstract":"Background The systemic immune-inflammation index (SII) is a novel marker for predicting the prognosis in patients with various diseases and cancers. We aimed to investigate the relationship between SII and disease activity in patients with Behçet disease (BD). Methods Our retrospective study included 513 patients with BD aged ≥18 years. The patients were classified into an active group (n=355) and an inactive group (n=158). Pearson correlation analysis was performed to elucidate correlations between the SII and other markers. Binary logistic regression analysis was used to determine BD-related risk factors. Receiver operating characteristic (ROC) curves were computed to assess cut-offs for the predictive value of the SII and other markers. Results Patients with active BD had a significantly higher SII (p<0.001) than those in the inactive group. ROC analysis revealed that the optimal SII cut-off value to identify BD activity was 526.23, with 70.4% sensitivity and 70.3% specificity. Pearson correlation coefficient (r) demonstrated a significant positive correlation between SII, and the C-reactive protein level (r=0.427, p<0.001), erythrocyte sedimentation rate (r=0.422, p<0.001), platelet- lymphocyte ratio (r=0.711, p<0.001), and neutrophil- lymphocyte ratio (r=0.672, p<0.001). According to binary logistic regression analysis, the SII (odds ratio [OR] 1.003; 95% confidence interval [CI] 1.001-1.004; p=0.002) was an independent risk factor for active BD. Conclusion The SII can be considered a novel predictor of BD activity.","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Book Review: I'm alive . . . for now. 书评：我还活着......暂时还活着。

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_574_2024

M K Mani

引用次数: 0

Achalasia: Pinstripe pattern. Achalasia：细条纹图案

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_144_2023

Yusaku Kajihara

引用次数: 0

Stigma and discrimination by healthcare providers towards patients diagnosed with HIV and tuberculosis: A study from India. 医疗服务提供者对确诊为艾滋病毒感染者和肺结核患者的羞辱和歧视：印度的一项研究。

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_1000_2022

Archana Siddaiah, Krishnamachari Srinivasan, Elsa Heylen, Maria L Ekstrand

引用次数: 0

The Epidemic Diseases Act (1897): A study of international and domestic pressures on British epidemic policy formation in India. 流行病法案》（1897 年）：关于英国在印度制定流行病政策所面临的国际和国内压力的研究。

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_420_2023

Pratima Yadav, Muraleedharan V R

{"title":"The Epidemic Diseases Act (1897): A study of international and domestic pressures on British epidemic policy formation in India.","authors":"Pratima Yadav, Muraleedharan V R","doi":"10.25259/NMJI_420_2023","DOIUrl":"10.25259/NMJI_420_2023","url":null,"abstract":"The Epidemic Diseases Act (EDA) was enacted in February 1897 by the Government of India to prevent and control the spread of the plague. Since then, the Act has become a key legal tool for the control of epidemics/pandemics in India. We attempted to understand the international and domestic pressures that led to the adoption of the EDA in three ways. First, we analyse the legislative structure (Bombay Municipal Act of 1888, Indian Railways Act of 1890, and Act I of 1870) that dealt with infectious or contagious diseases in colonial India before the EDA came into force. Second, we focus on the linkages between international and domestic pressures that necessitated the adoption of the EDA. Third, we analyse the discussions of the Council of the Governor General of India on the bill titled 'A Bill to Provide for the better prevention of the spread of Dangerous Epidemic Diseases', which later became the Epidemic Diseases Act No. III of 1897. We situate the EDA in an international context of International Sanitary Conferences, quarantine, trade concerns, and pilgrimage to Mecca in order to understand the pressures that impacted British epidemic policy formation in colonial India.","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EMPULSE trial: Time to use SGLT-2 inhibitors in acute heart failure? EMPULSE 试验：是时候在急性心力衰竭中使用 SGLT-2 抑制剂了吗？

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_1190_2023

Shubhajeet Roy, Mehul Saxena, Akshyaya Pradhan

引用次数: 0

Membranous tonsillitis: Aetiology, prevalence and prescribing patterns in patients with upper respiratory tract infection. 膜性扁桃体炎：上呼吸道感染患者的病因、发病率和处方模式。

The National medical journal of India Pub Date : 2024-03-01 DOI: 10.25259/NMJI_690_21

Yilmaz Seçilmis

{"title":"Membranous tonsillitis: Aetiology, prevalence and prescribing patterns in patients with upper respiratory tract infection.","authors":"Yilmaz Seçilmis","doi":"10.25259/NMJI_690_21","DOIUrl":"10.25259/NMJI_690_21","url":null,"abstract":"Background Membranous tonsillitis is one of the most common forms of acute tonsillitis in childhood. Although many different microorganisms may cause this disease, clinicians generally consider bacterial agents as a possible cause and prescribe a penicillin-group of antibiotic. This study aimed to determine the aetiology of membranous tonsillitis and prescribing errors. In addition, we investigated the effectiveness of epidemiological, clinical and laboratory parameters and their role in guiding treatment. Methods We did this retrospective study at the paediatric emergency department of a tertiary referral hospital including 423 outpatient children aged 0 to 18 years diagnosed with membranous tonsillitis. Results Group A beta-haemolytic streptococcus was found in 132 (31.2%) patients, Epstein-Barr virus (EBV) in 103 (24.3%), and other viral aetiologies in 188 (44.4%). The prescription rate of antibiotics in the EBV-positive group was 27%, and Downey cells were seen at a rate of 98% in this group. Only 7% of patients with a positive throat culture were started on appropriate antibiotics. Conclusion EBV and group A beta-haemolytic streptococcus were the most common causes of membranous tonsillitis. Throat culture and peripheral blood smears are the most useful tests for paediatric emergency clinicians; these are fast and can help ensure correct diagnosis and guide treatment in almost all patients.","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence, risk factors and genotype distribution of human papillomavirus infection among women with and without invasive cervical cancer: Findings from a hospital-based study in Bihar, India. 患有和未患有浸润性宫颈癌的妇女中人类乳头瘤病毒感染的流行率、风险因素和基因型分布：印度比哈尔邦一项基于医院的研究结果。

The National medical journal of India Pub Date : 2024-01-01 DOI: 10.25259/NMJI_634_21

Sangeeta Pankaj, Jyotsana Rani, Pratibha Kumari, Kavya Abhilashi, Vijayanand Choudhary, Satya Kumari, Shivendra Kumar Shahi, Babban Jee

{"title":"Prevalence, risk factors and genotype distribution of human papillomavirus infection among women with and without invasive cervical cancer: Findings from a hospital-based study in Bihar, India.","authors":"Sangeeta Pankaj, Jyotsana Rani, Pratibha Kumari, Kavya Abhilashi, Vijayanand Choudhary, Satya Kumari, Shivendra Kumar Shahi, Babban Jee","doi":"10.25259/NMJI_634_21","DOIUrl":"https://doi.org/10.25259/NMJI_634_21","url":null,"abstract":"Background Human papillomavirus (HPV) infection is largely responsible for the development of invasive cervical cancer (ICC). Its prevalence, risk factors and genotype distribution among women residing in Bihar (third most populous Indian state) with and without ICC are not well known. Methods In this hospital-based study, we followed up 1439 participants with cytology and HPV report. HPV detection and genotyping were performed using the TaqMan-based real-time PCR method. Clinical and sociodemographic data were collected and analysed using statistical methods. Results The overall prevalence of HPV infection was 37.3% (537/1439) and 11 different types of HPV genotypes were observed. Higher HPV positivity was found in premalignant, intraepithelial and invasive malignant lesions of the cervix; 73.8% (93/126) of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and high-grade squamous intraepithelial lesions (HSIL) and 93.4% (114/122) of invasive malignancies were infected with HPV in comparison to only 26.1% (245/938) of negative for intraepithelial lesion or malignancy (NILM) cytology. Moreover, HPV was found in 95.2% (236/248) of histologically confirmed cases of carcinoma cervix. HPV16 and HPV18 infections were reported in 78.2% (194/248) and 8.9% (22/248), respectively. The remaining patients had infection with other high-risk strains/co-infection with multiple strains or were HPV-negative. Various socio-demographic factors including women >50 years of age, >10 years of marriage and high parity were significantly associated with HPV infection. Conclusion Our data suggest that HPV16 infection may be the major cause for ICC among women residing in Bihar. Our findings may serve as a baseline for developing an appropriate screening and vaccination strategy for Bihar.","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141891531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Camphor poisoning in an adult: Seizures manifesting as 'mis-purposed' drug effect. 成人樟脑中毒：表现为 "误用 "药物效应的癫痫发作。

The National medical journal of India Pub Date : 2024-01-01 DOI: 10.25259/NMJI_2_21

Ankit Kumar Sahu, Sonika Rathoor

引用次数: 0