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Medecine sciences : M/S最新文献

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[Financial incentives to achieve health-related behavioral goals: State of play and unresolved questions]. [实现与健康有关的行为目标的财政激励:发挥作用的状态和未解决的问题]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022005
David Crainich
{"title":"[Financial incentives to achieve health-related behavioral goals: State of play and unresolved questions].","authors":"David Crainich","doi":"10.1051/medsci/2022005","DOIUrl":"https://doi.org/10.1051/medsci/2022005","url":null,"abstract":"<p><p>Programs providing monetary rewards to individuals who achieve a health-related goal (quitting smoking, losing weight, etc.) aim at promoting healthy behaviors. While these programs seem to achieve their objective in the short run, their ability to provoke lasting changes remains to be demonstrated. The identification of granting mechanisms likely to maximize the incentive effect of these rewards should be based on knowledge about individual attitudes evidenced by behavioral economics. As the latter has shown that preferences toward risk vary from one individual to another, these incentive mechanisms should be tailor-made according to individual preferences.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"198-204"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39810341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Macrophage involvement in juvenile arthritis onset: LACC1 bridges the gap?] 巨噬细胞参与幼年关节炎发病:LACC1填补空白?]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021253
Anne-Laure Mathieu, Ommar Omarjee, Thierry Walzer, Alexandre Belot
{"title":"[Macrophage involvement in juvenile arthritis onset: LACC1 bridges the gap?]","authors":"Anne-Laure Mathieu,&nbsp;Ommar Omarjee,&nbsp;Thierry Walzer,&nbsp;Alexandre Belot","doi":"10.1051/medsci/2021253","DOIUrl":"https://doi.org/10.1051/medsci/2021253","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"133-135"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39934866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Who wants to be a SIGAPS millionaire?] 谁想成为SIGAPS百万富翁?]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022006
Louise Benoit
{"title":"[Who wants to be a SIGAPS millionaire?]","authors":"Louise Benoit","doi":"10.1051/medsci/2022006","DOIUrl":"https://doi.org/10.1051/medsci/2022006","url":null,"abstract":"<p><p>In order to promote biomedical research, the French ministry of Solidarity and Health has developed a software that is used to rate medical doctors according to their scientific production: the SIGAPS points (System of Interrogation, Management and Analysis of Scientific Publications). These points (1-32 points) are attributed after the publication of a scientific paper according to the quality of the journal (based on the impact factor) and the doctor's rank among the authors. These points are then transformed into a sum of money received by the health facility (1 point = approximately 648 euros), 4 years in a row. Does this \"fee-for-service\" encourage doctors to publish quickly at any price, regardless of the quality of their research?</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"215-217"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39810780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Phthalates: A risk factor for cerebrovascular function in adult male mice]. [邻苯二甲酸盐:成年雄性小鼠脑血管功能的危险因素]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021256
Delnia Ahmadpour, Sakina Mhaouty-Kodja, Valérie Grange-Messent
{"title":"[Phthalates: A risk factor for cerebrovascular function in adult male mice].","authors":"Delnia Ahmadpour,&nbsp;Sakina Mhaouty-Kodja,&nbsp;Valérie Grange-Messent","doi":"10.1051/medsci/2021256","DOIUrl":"https://doi.org/10.1051/medsci/2021256","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"141-144"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sjögren's syndrome: Towards precision medicine]. [Sjögren综合症:走向精准医疗]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021258
Laurence Laigle, Christelle Le Dantec, Perrine Soret, Emiko Desvaux, Sandra Hubert, Nathan Foulquier, Philippe Moingeon, Mickaël Guedj, Jacques-Olivier Pers
{"title":"[Sjögren's syndrome: Towards precision medicine].","authors":"Laurence Laigle,&nbsp;Christelle Le Dantec,&nbsp;Perrine Soret,&nbsp;Emiko Desvaux,&nbsp;Sandra Hubert,&nbsp;Nathan Foulquier,&nbsp;Philippe Moingeon,&nbsp;Mickaël Guedj,&nbsp;Jacques-Olivier Pers","doi":"10.1051/medsci/2021258","DOIUrl":"https://doi.org/10.1051/medsci/2021258","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"148-151"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Inhibition of anti-tumor immunity by NF-κB: Toward therapeutic targeting?] NF-κB对抗肿瘤免疫的抑制作用:走向治疗靶点?]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022013
Lara Revol-Bauz, Yenkel Grinberg-Bleyer
{"title":"[Inhibition of anti-tumor immunity by NF-κB: Toward therapeutic targeting?]","authors":"Lara Revol-Bauz,&nbsp;Yenkel Grinberg-Bleyer","doi":"10.1051/medsci/2022013","DOIUrl":"https://doi.org/10.1051/medsci/2022013","url":null,"abstract":"m/s n° 2, vol. 38, février 2022 https://doi.org/10.1051/medsci/2022013 > Les travaux des dernières années ont formellement établi le lien entre croissance tumorale et qualité de la réponse immunitaire. Ces études ont notamment permis le développement et l’utilisation en clinique de différentes immunothérapies, notamment l’utilisation d’inhibiteurs de points de contrôle immunitaire, qui ont révolutionné la prise en charge de certains cancers [1] (➜). Néanmoins, les voies de signalisation et les facteurs de transcription impliqués dans les réponses proet anti-tumorales restent imparfaitement définis. Historiquement, le facteur de transcription NF-κB (nuclear factor kappa-lightchain-enhancer of activated B cells) a été décrit comme un modulateur majeur des réponses immunitaires innées et adaptatives [2]. NF-κB est un complexe multimoléculaire constitué de plusieurs sousunités qui fonctionnent sous la forme de différents homoou hétérodimères : les sous-unités NF-κB1, RelA et c-Rel de la voie canonique ; et les sous-unités NF-κB2 et RelB de la voie alternative. Le rôle spécifique de chacune des protéines, qui sont des facteurs de transcription, reste mal compris, mais plusieurs études récentes ont mis en évidence un rôle délétère de différentes sous-unités au cours du processus d’échappement des tumeurs au système immunitaire.","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"230-232"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39810784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Reaching for the stars: How astrocytes regulate positive emotions via oxytocin]. [摘星:星形胶质细胞如何通过催产素调节积极情绪]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021255
Angel Baudon, Alexandre Charlet
{"title":"[Reaching for the stars: How astrocytes regulate positive emotions via oxytocin].","authors":"Angel Baudon,&nbsp;Alexandre Charlet","doi":"10.1051/medsci/2021255","DOIUrl":"https://doi.org/10.1051/medsci/2021255","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"138-140"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Contraception in the context of PCOS]. 【多囊卵巢综合征背景下的避孕】。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022002
Poli Mara Spritzer
{"title":"[Contraception in the context of PCOS].","authors":"Poli Mara Spritzer","doi":"10.1051/medsci/2022002","DOIUrl":"https://doi.org/10.1051/medsci/2022002","url":null,"abstract":"<p><p>Polycystic ovary syndrome is a frequent endocrinopathy, affecting between 8% and 13% of women of childbearing age and characterized by hyperandrogenism, chronic anovulation and polycystic ovary morphology. Women with PCOS also have a higher prevalence of obesity, metabolic disorders and an increased risk of diabetes, systemic hypertension and dyslipidemia. The first-line treatment for women with PCOS who do not plan to conceive in the short term includes lifestyle changes and combined oral contraceptives, offering, in addition to contraception, endometrial protection and reduction of hyperandrogenism. Progestin-only contraceptives are recommended for women with contraindications to estrogen contained in combined oral contraceptives. Cosmetic procedures can be added to pharmacological treatment for hirsutism. Severe cases may require anti-androgen drugs which will be combined with contraception. For overweight patients with cardiometabolic risk factors, including insulin resistance or dysglycemia, metformin may also be combined with contraception. In conclusion, the choice of contraception in women with PCOS includes an approach tailored to the individual needs of each patient.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"177-181"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Metabolism: The renaissance!] 新陈代谢:文艺复兴!］
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022009
Pascal Ferré
{"title":"[Metabolism: The renaissance!]","authors":"Pascal Ferré","doi":"10.1051/medsci/2022009","DOIUrl":"https://doi.org/10.1051/medsci/2022009","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"123-124"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39934862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Good mutant clones eliminate nascent tumours]. [好的突变克隆消除新生肿瘤]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-01-01 Epub Date: 2022-01-21 DOI: 10.1051/medsci/2021239
Bertrand Jordan
{"title":"[Good mutant clones eliminate nascent tumours].","authors":"Bertrand Jordan","doi":"10.1051/medsci/2021239","DOIUrl":"https://doi.org/10.1051/medsci/2021239","url":null,"abstract":"<p><p>Most (>90%) of the nascent tumours present in murine oesophageal epithelium after mutagen treatment disappear during the following months. This elimination is driven by mutant (but phenotypically normal) clones that gradually outcompete and eliminate the neoplastic clones. This novel mechanism, demonstrated in the mouse, is probably active in humans as well and may have important clinical implications.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 1","pages":"101-106"},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39846052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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