发布求助
文献互助 智能选刊 最新文献

Medecine sciences : M/S最新文献

筛选
英文 中文
[Longevity of rockfishes]. [岩石鱼的寿命]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021259
Bertrand Jordan
{"title":"[Longevity of rockfishes].","authors":"Bertrand Jordan","doi":"10.1051/medsci/2021259","DOIUrl":"https://doi.org/10.1051/medsci/2021259","url":null,"abstract":"<p><p>The existence of a number of highly similar rockfish species with very different life spans has motivated extensive DNA sequencing studies that have uncovered strong selection for genes involved in DNA maintenance and in control of inflammation, highlighting the role these may play in the avoidance of senescence.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"218-221"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39810781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Autophagy modulation by viruses: An important role in tumor progression]. 病毒调节自噬:在肿瘤进展中的重要作用。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022010
Lucas Leonardi, Sophie Sibéril, Marco Alifano, Isabelle Cremer, Pierre-Emmanuel Joubert
{"title":"[Autophagy modulation by viruses: An important role in tumor progression].","authors":"Lucas Leonardi,&nbsp;Sophie Sibéril,&nbsp;Marco Alifano,&nbsp;Isabelle Cremer,&nbsp;Pierre-Emmanuel Joubert","doi":"10.1051/medsci/2022010","DOIUrl":"https://doi.org/10.1051/medsci/2022010","url":null,"abstract":"<p><p>Autophagy is an important process for cellular homeostasis at critical steps of development or in response to environmental stress. In the context of cancers, autophagy has a significant impact on tumor occurrence and tumor cell growth. On the one hand, autophagy limits the transformation of precancerous cells into cancer cells at an early stage. However, on the other hand, it promotes cell survival, cell proliferation, metastasis and resistance to anti-tumor therapies in more advanced tumors. Autophagy can be induced by a variety of extracellular and intracellular stimulus. Viral infections have often been associated with a modulation of autophagy, with variable impacts on viral replication and on the survival of infected cells depending on the model studied. In a tumor context, the modulation of autophagy induced by the viral infection of tumor cells seems to have a significant impact on tumor progression. The aim of this review article is to present recent findings regarding the consequences of autophagy disturbance by viral infections on tumor behavior.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"159-167"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Western diet, obesity and bariatric surgery modulate anxiety, eating habits and the brain responses to sweet taste]. [西方饮食、肥胖和减肥手术调节焦虑、饮食习惯和大脑对甜味的反应]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021252
Yentl Gautier, Damien Bergeat, Yann Serrand, Noémie Réthoré, Mathilde Mahérault, Charles-Henri Malbert, Paul Meurice, Nicolas Coquery, Romain Moirand, David Val-Laillet
{"title":"[Western diet, obesity and bariatric surgery modulate anxiety, eating habits and the brain responses to sweet taste].","authors":"Yentl Gautier,&nbsp;Damien Bergeat,&nbsp;Yann Serrand,&nbsp;Noémie Réthoré,&nbsp;Mathilde Mahérault,&nbsp;Charles-Henri Malbert,&nbsp;Paul Meurice,&nbsp;Nicolas Coquery,&nbsp;Romain Moirand,&nbsp;David Val-Laillet","doi":"10.1051/medsci/2021252","DOIUrl":"https://doi.org/10.1051/medsci/2021252","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"125-129"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39934864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The importance of telomeres in human herpesvirus-6A/B infections]. [端粒在人类疱疹病毒6a /B感染中的重要性]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022008
Vanessa Collin, Louis Flamand
{"title":"[The importance of telomeres in human herpesvirus-6A/B infections].","authors":"Vanessa Collin,&nbsp;Louis Flamand","doi":"10.1051/medsci/2022008","DOIUrl":"https://doi.org/10.1051/medsci/2022008","url":null,"abstract":"<p><p>Herpesviruses are undisputed masters of disguise. The ability to become invisible to the immune system effectors is a complex process resting on a variety of stealth approaches. Among these, human herpesviruses-6A and -6B (HHV-6A/B) have developed the unique ability to integrate their genome within the ends of chromosomes allowing viral persistence in the absence of viral protein expression. This aptitude, unique to HHV-6A/B among human herpesviruses, requires close interactions between the telomeric regions of chromosomes and the viral genome. In this review article, the biology of telomeres and the mechanisms responsible for viral integration are discussed. In closing, the possible biological consequences of HHV-6A/B integration into chromosomal DNA are discussed.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"168-176"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rings and braids: Correlative microscopy reveals the structure of axonal actin]. [环状和辫状:相关显微镜显示轴突肌动蛋白的结构]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021254
Stéphane Vassilopoulos, Christophe Leterrier
{"title":"[Rings and braids: Correlative microscopy reveals the structure of axonal actin].","authors":"Stéphane Vassilopoulos,&nbsp;Christophe Leterrier","doi":"10.1051/medsci/2021254","DOIUrl":"https://doi.org/10.1051/medsci/2021254","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"130-133"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39934865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mitochondrial dysfunction as a new therapeutic target to restore exhausted immune responses against HBV]. [线粒体功能障碍作为一种新的治疗靶点来恢复对HBV耗尽的免疫反应]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022011
Léa Clément, Barbara Testoni
{"title":"[Mitochondrial dysfunction as a new therapeutic target to restore exhausted immune responses against HBV].","authors":"Léa Clément,&nbsp;Barbara Testoni","doi":"10.1051/medsci/2022011","DOIUrl":"https://doi.org/10.1051/medsci/2022011","url":null,"abstract":"Le dysfonctionnement mitochondrial, nouvelle cible thérapeutique pour restaurer les réponses immunitaires épuisées contre le VHB.\u0000 Dans le cadre d’un partenariat avec médecine/sciences, et pour la quatrième année consécutive, des étudiants du module d’enseignement « d’immunologie virologie et cancer » du Master de cancérologie de Lyon présentent une analyse d’articles scientifiques récents faisant état d’observations innovantes et importantes. Ce travail a été encadré par des chercheurs confirmés du Centre de Recherche en Cancérologie de Lyon (CRCL). Le Master de cancérologie (université Claude Bernard Lyon1 - VetAgroSup) accueille chaque année 40 étudiants en M1 et environ 80 en M2. Ce master dit « d’excellence » (master international labellisé Université de Lyon) assure aux étudiants de M1 une formation à la cancérologie reposant sur un socle de base commun (biologie cellulaire, moléculaire, immunologie, bio-statistique, épidémiologie, recherche translationnelle, etc.). Les étudiants de M2 peuvent choisir l’un des parcours suivants : 1) Biologie du Cancer ; 2) Innovations thérapeutiques en Cancérologie ; 3) Médecine de précision en Cancérologie ; 4) Cancer Bio-engineering. Le Master de cancérologie de Lyon repose sur une forte implication des chercheurs et enseignants-chercheurs du laboratoire d'excellence en développement et cancérologie (LabEx DEVweCAN), ainsi que sur un partenariat solide avec plusieurs instituts à travers le monde dont le MIT (Massachusetts Institute of Technology, Cambridge, États-Unis), l'université d'Harvard (Boston, États-Unis), l'université de San Diego (États-Unis), University of City of London (UCL), le Beatson Institute de Glasgow (Royaume-Uni), les universités de Shanghai Jiao Tong (République populaire de Chine, RPC), de Tokyo et de Tohoku (Japon), de Melbourne (Australie) et d'Auckland (Nouvelle-Zélande).","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"223-226"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39810782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[AMPK activity is a gatekeeper of the intestinal epithelial barrier]. [AMPK活性是肠上皮屏障的守门人]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2021251
Séverine Olivier, Hanna Diounou, Marc Foretz, Sandra Guilmeau, Noëmie Daniel, André Marette, Malvyne Rolli-Derkinderen, Benoit Viollet
{"title":"[AMPK activity is a gatekeeper of the intestinal epithelial barrier].","authors":"Séverine Olivier,&nbsp;Hanna Diounou,&nbsp;Marc Foretz,&nbsp;Sandra Guilmeau,&nbsp;Noëmie Daniel,&nbsp;André Marette,&nbsp;Malvyne Rolli-Derkinderen,&nbsp;Benoit Viollet","doi":"10.1051/medsci/2021251","DOIUrl":"https://doi.org/10.1051/medsci/2021251","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"136-138"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Is understanding the mechanism of perception possible?] 理解感知的机制是可能的吗?]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022004
Jean-Pierre Henry
{"title":"[Is understanding the mechanism of perception possible?]","authors":"Jean-Pierre Henry","doi":"10.1051/medsci/2022004","DOIUrl":"https://doi.org/10.1051/medsci/2022004","url":null,"abstract":"Perception is the understanding by the brain of the different sensory information. In humans, information is mostly visual and is conveyed to the occipital cortex. MRI techniques suggest that it is deciphered in different areas of the temporal cortex, depending upon the observed scene. The neural codes used by neurons of these areas will be discussed in two instances: Recognition of written words and of faces. In the first case, an hypothesis using basic properties of neurons and hierarchy of local combination detectors, accounts for the invariance of their visual form. That it is relevant is emphasized by its successful application to reading mechanism. In the second more recent instance, recognition of human faces by macaques is shown to reside in neuron patches in the inferior temporal cortex, forming a system identifying faces with view invariance. The code allowing facial identification using the electrical activity of 200 neurons was cracked.","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"191-197"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dengue virus circulation in West Africa: An emerging public health issue]. [西非登革热病毒传播:一个新出现的公共卫生问题]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022007
Bachirou Tinto, Dramane Kania, Thérèse Samdapawindé Kagone, Amadou Dicko, Isidore Traore, Nathalie de Rekeneire, Brice Wilfried Bicaba, Hervé Hien, Philippe Van de Perre, Yannick Simonin, Sara Salinas
{"title":"[Dengue virus circulation in West Africa: An emerging public health issue].","authors":"Bachirou Tinto,&nbsp;Dramane Kania,&nbsp;Thérèse Samdapawindé Kagone,&nbsp;Amadou Dicko,&nbsp;Isidore Traore,&nbsp;Nathalie de Rekeneire,&nbsp;Brice Wilfried Bicaba,&nbsp;Hervé Hien,&nbsp;Philippe Van de Perre,&nbsp;Yannick Simonin,&nbsp;Sara Salinas","doi":"10.1051/medsci/2022007","DOIUrl":"https://doi.org/10.1051/medsci/2022007","url":null,"abstract":"<p><p>Dengue is the most widespread arbovirosis in the world, with approximately 390 million cases per year, 96 millions of which have clinical manifestations and 25,000 deaths. In West Africa, the circulation of this virus in human populations was first reported in the 1960s in Nigeria. Clinical diagnosis of dengue in West Africa is made difficult by the existence of other diseases with similar clinical presentations. Biological diagnosis remains therefore the only alternative. This biological diagnosis requires high quality equipment and well-trained personnel, which are not always available in resource-limited countries. Thus, many cases of dengue fever are consistently reported as malaria, leading to mismanagement, which can have serious consequences on the health status of patients. It is therefore necessary to set up surveillance systems for febrile infections of unknown origin in Africa by strengthening the diagnostic capacities of national laboratories.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"152-158"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Transition of care from childhood and adolescence to adulthood in nephrology]. [肾病学中从儿童和青少年到成年护理的过渡]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-02-01 Epub Date: 2022-02-18 DOI: 10.1051/medsci/2022003
Marie-Alice Macher, Robert Novo, Véronique Baudouin
{"title":"[Transition of care from childhood and adolescence to adulthood in nephrology].","authors":"Marie-Alice Macher,&nbsp;Robert Novo,&nbsp;Véronique Baudouin","doi":"10.1051/medsci/2022003","DOIUrl":"https://doi.org/10.1051/medsci/2022003","url":null,"abstract":"<p><p>For a young patient suffering from a chronic disease, the transition from pediatric to adult care unit is a tricky step, with a high risk of poor therapeutic compliance, loss of follow-up, and possibly tragic consequences. Better knowledge of these risks has led to a strong mobilization of pediatricians and medical teams for adult care over the last ten years, and the notion of health care transition from childhood to adulthood tends to replace simple care transfer. Transition is a step-by-step well-planned process, over several years, aimed at preparing an adolescent to become an independent empowered young adult, and at accompanying him after the change of healthcare team. Chronic renal diseases beginning in childhood have a very different etiological distribution from those occurring in adulthood. They are often rare diseases benefiting from the care of specific reference centers. It is especially for severe renal failure, and more specifically for young transplant recipients, that transition programs have been developed. We describe here the main recommendations and current transition programs.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 2","pages":"182-190"},"PeriodicalIF":0.7,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39796305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信