Obstetric Medicine最新文献_第4页

Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study. 在多种族妊娠糖尿病患者中，更严格的血糖指标对妊娠结局的影响：一项回顾性、单中心观察性研究。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-04 DOI: 10.1177/1753495X261445509

Mohammed Sb Huda, Niki Margari, Nafisa Islam, Hannah Jaumdally, Kate Wiles, Rehan Khan, Peter Jacob, Elena Greco, Stamatina Iliodromiti, Anita Sanghi, Shakila Thangaratinam

{"title":"Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study.","authors":"Mohammed Sb Huda, Niki Margari, Nafisa Islam, Hannah Jaumdally, Kate Wiles, Rehan Khan, Peter Jacob, Elena Greco, Stamatina Iliodromiti, Anita Sanghi, Shakila Thangaratinam","doi":"10.1177/1753495X261445509","DOIUrl":"https://doi.org/10.1177/1753495X261445509","url":null,"abstract":"Aims: To determine the impact of tighter glycaemic targets for gestational diabetes.Methods: Retrospective data analysis before and after introducing tighter glucose targets.Results: In 2265 pregnancies there was no change in large-for-gestational age babies (Odds ratio (OR) 1.1; 95% Confidence interval (CI) 0.8-1.6) and macrosomia (OR 1.0; 95% CI 0.6-1.7) following tighter glucose targets. Gestational hypertension (OR 0.4; 95% CI 0.2-0.7), spontaneous vaginal birth (OR 0.6; 95% CI 0.4-0.9) reduced and pharmacological treatment increased (OR 2.2; 95% CI 1.7-2.8).Composite adverse neonatal outcome (perinatal death, shoulder dystocia, fracture, nerve palsy) (OR 0.6; CI 0.02-14.2 p = 0.76)), Apgar<7 at 5 min, neonatal hypoglycaemia, respiratory distress syndrome or neonatal unit admission did not change but neonatal jaundice was reduced (OR 0.4; 95% CI 0.2-0.8).Conclusions: Tighter glycaemic targets had no impact on large-for-gestational age babies or composite adverse neonatal outcomes. There was reduced spontaneous vaginal birth, gestational hypertension, neonatal jaundice and increased pharmacological treatment.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261445509"},"PeriodicalIF":0.5,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Our peer-review problem. 我们的同行评议问题。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-04 DOI: 10.1177/1753495X261446731

Stephen E Lapinsky, Charlotte Frise

引用次数: 0

Delayed-type hypersensitivity to low-molecular-weight heparin and cross-reactivity to fondaparinux and danaparoid in a twin pregnancy. 双胎妊娠对低分子肝素的迟发性超敏反应和对氟达肝素和丹那肝素的交叉反应。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-25 DOI: 10.1177/1753495X261445510

Emmeline House, Gianna Pastore, Caroline Wilson, Adam Morton

引用次数: 0

The use of dexamphetamine for narcolepsy during pregnancy: A case series and literature review. 妊娠期间使用右安非他明治疗发作性睡病：一个病例系列和文献综述。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-20 DOI: 10.1177/1753495X261439640

Katie Lane, Claudia Steinbock, Edward Carter, Karin Lust, Ann-Maree Craven

{"title":"The use of dexamphetamine for narcolepsy during pregnancy: A case series and literature review.","authors":"Katie Lane, Claudia Steinbock, Edward Carter, Karin Lust, Ann-Maree Craven","doi":"10.1177/1753495X261439640","DOIUrl":"10.1177/1753495X261439640","url":null,"abstract":"Dexamphetamine, a central nervous system stimulant, is increasingly prescribed to women of childbearing age, yet data on its safety in pregnancy, particularly for narcolepsy, remains limited. This case series examined pregnancy outcomes in 10 women with narcolepsy or idiopathic hypersomnolence at the Royal Brisbane and Women's Hospital who were prescribed dexamphetamine during pregnancy. Six women continued therapy throughout pregnancy. Apart from one case complicated by congenital CMV infection, all pregnancies progressed to the late third trimester with favourable neonatal outcomes. No cases of pre-eclampsia were observed; one woman developed gestational hypertension. All neonates had normal Apgar scores, with the exception of two where the Apgars were not recorded. However, no neonates required additional ventilatory support. Our findings suggest that therapeutic dexamphetamine use for narcolepsy may not be associated with adverse obstetric or neonatal outcomes. Individualised counselling is essential to balance maternal functional needs against potential pregnancy risks.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261439640"},"PeriodicalIF":0.7,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13096000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disseminated amoebiasis in pregnancy: A maternal near-miss. 妊娠期弥散性阿米巴病：母亲的侥幸。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-10 DOI: 10.1177/1753495X261437740

Avantika Gupta, Satish Choudhury, Piyush Pathak, Diksha Singla, Aman Kumar Phulwani, Tanya Sharma

引用次数: 0

Pregnant woman with Jervell and Lange-Nielsen syndrome: a case report. 孕妇患杰维尔-兰格-尼尔森综合征1例报告。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-09 DOI: 10.1177/1753495X261439230

Sivaranjani P, Jayalakshmi Durairaj, Kubera N S, Ashwini Vishalakshi L

引用次数: 0

Circadian misalignment, dietary timing, and maternal morbidity. 昼夜节律失调，饮食时间和产妇发病率。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-06 DOI: 10.1177/1753495X261439641

Nádia Raci Marques Pereira, Isabela Antunes Ishikura, Sergio Tufik, Helena Hachul

引用次数: 0

Renal angiomyolipoma in pregnancy - A review. 妊娠期肾血管平滑肌脂肪瘤的研究进展。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-06 DOI: 10.1177/1753495X261439226

Adam Morton

引用次数: 0

Methanol poisoning in pregnancy: A hidden threat in obstetric care. 孕期甲醇中毒：产科护理的潜在威胁。

IF 0.7

Obstetric Medicine Pub Date : 2026-04-06 DOI: 10.1177/1753495X261439673

Antônio Braga, Gustavo Yano Callado, Gabriela Paiva, Jorge Rezende-Filho, Edward Araujo Júnior

{"title":"Methanol poisoning in pregnancy: A hidden threat in obstetric care.","authors":"Antônio Braga, Gustavo Yano Callado, Gabriela Paiva, Jorge Rezende-Filho, Edward Araujo Júnior","doi":"10.1177/1753495X261439673","DOIUrl":"10.1177/1753495X261439673","url":null,"abstract":"Maternal methanol poisoning is rare but carries significant risks for both mother and fetus, including metabolic acidosis, visual and neurologic injury, and fetal compromise. Methanol freely crosses the placenta, and fetal metabolism of formate is limited, making the fetus particularly susceptible to hypoxic and metabolic injury. Clinical recognition is challenging due to nonspecific early symptoms, and prompt maternal stabilization with antidotal therapy, folate supplementation, and hemodialysis is critical to prevent irreversible fetal damage. Preventive strategies require a multidimensional approach, including public health education, regulatory oversight of methanol-containing products, and standardized clinical protocols for early recognition and treatment. Addressing social determinants of health and ensuring equitable access to maternal care are essential to mitigate risk among vulnerable populations. This review integrates biomedical, obstetric, and public health perspectives to provide a comprehensive overview of maternal-fetal toxicity, clinical presentation, diagnosis, management, and perinatal outcomes.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261439673"},"PeriodicalIF":0.7,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal and fetal outcomes in pregnancies affected by mixed connective tissue disease. 混合性结缔组织病影响妊娠的母胎结局

IF 0.7

Obstetric Medicine Pub Date : 2026-04-01 DOI: 10.1177/1753495X261427244

Shannon Y Zhou, Lily Holden, Melody Colon, Alexandra Cregan, Sabrina C Burn

{"title":"Maternal and fetal outcomes in pregnancies affected by mixed connective tissue disease.","authors":"Shannon Y Zhou, Lily Holden, Melody Colon, Alexandra Cregan, Sabrina C Burn","doi":"10.1177/1753495X261427244","DOIUrl":"10.1177/1753495X261427244","url":null,"abstract":"Introduction: Mixed connective tissue disease (MCTD) is an autoimmune condition with overlapping features of lupus, systemic sclerosis, and polymyositis. Maternal-fetal outcomes specific to MCTD remain poorly characterized; a scoping review was conducted.Methods: Five databases were queried. Extracted data included demographics, antibody profiles, symptoms, treatments, and maternal-fetal outcomes. Descriptive analysis was performed.Results: Of 269 articles, 33 met inclusion criteria, including 375 pregnancies. Common symptoms and disease manifestations included Raynaud's phenomenon, arthralgias, and sclerodactyly. Treatments included hydroxychloroquine, azathioprine, and corticosteroids. Maternal complications included interstitial lung disease (21.4%), gestational hypertension (HTN) (15.6%), chronic HTN (7.0%), pulmonary HTN (9.8%), eclampsia (1.4%), miscarriage (20.3%), preterm birth (19.6%), and stillbirth (8.1%). Fetal complications included chondrodysplasia punctata (18.2%), demise (6.5%), neonatal lupus erythematosus (3.3%), and congenital heart block (1.0%).Conclusion: While most MCTD pregnancies resulted in live birth, they carry elevated maternal and perinatal risks that warrant heightened surveillance and tailored management.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261427244"},"PeriodicalIF":0.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0