Obstetric Medicine最新文献_第3页

Eplerenone in pregnancy. 每个人都在怀孕。

IF 0.7

Obstetric Medicine Pub Date : 2026-06-24 DOI: 10.1177/1753495X261463148

Adam Morton

引用次数: 0

Postpartum therapeutic anticoagulation and uterine wall haematoma: A case report. 产后抗凝治疗与子宫壁血肿1例。

IF 0.7

Obstetric Medicine Pub Date : 2026-06-23 DOI: 10.1177/1753495X261460131

Satoshi Shinohara, Taiga Matsudo, Genki Yasuda, Mayuko Kasai, Ken Umetani, Rei Sunami

{"title":"Postpartum therapeutic anticoagulation and uterine wall haematoma: A case report.","authors":"Satoshi Shinohara, Taiga Matsudo, Genki Yasuda, Mayuko Kasai, Ken Umetani, Rei Sunami","doi":"10.1177/1753495X261460131","DOIUrl":"https://doi.org/10.1177/1753495X261460131","url":null,"abstract":"Deep vein thrombosis (DVT) during pregnancy requires timely anticoagulation to prevent complications; however, the early postpartum period is associated with an inherently elevated risk of hemorrhage, creating competing management priorities. Herein, we describe the case of a woman with dichorionic diamniotic twin pregnancy who developed progressive femoral DVT despite therapeutic unfractionated heparin (UFH) and concurrent preeclampsia and acute kidney injury. Although postoperative hemostasis after caesarean delivery initially appeared stable, therapeutic UFH was restarted early as DVT continued to progress, requiring the resumption of standard treatment. Despite seemingly adequate early hemostasis, the woman developed a massive uterine wall hematoma that required uterine artery embolization. This case illustrates the complexity of balancing thrombotic urgency against fragile postpartum hemostasis and highlights the importance of individualized anticoagulation strategies for obstetricians, surgeons, anesthesiologists, and perioperative teams caring for high-risk patients.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261460131"},"PeriodicalIF":0.7,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13290739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148334213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prevalence of the common LCHAD c.1528G>C p.(Glu510Gln) pathogenic variant in women diagnosed with acute fatty liver of pregnancy. 妊娠期急性脂肪肝女性常见LCHAD C . 1528g . > . C . p.（Glu510Gln）致病变异的患病率

IF 0.7

Obstetric Medicine Pub Date : 2026-06-19 DOI: 10.1177/1753495X261460139

Jinwen He, Liza Phillips, Janelle Nisbet, Adam Morton

引用次数: 0

Renal tubular acidosis (RTA) complicated pregnancies: A tertiary centre experience. 肾小管酸中毒（RTA）并发症妊娠：三级中心经验。

IF 0.5

Obstetric Medicine Pub Date : 2026-06-10 DOI: 10.1177/1753495X261456364

Arati Singh, Tarakeswari Surapaneni, Hemamalini Vadlamani

{"title":"Renal tubular acidosis (RTA) complicated pregnancies: A tertiary centre experience.","authors":"Arati Singh, Tarakeswari Surapaneni, Hemamalini Vadlamani","doi":"10.1177/1753495X261456364","DOIUrl":"https://doi.org/10.1177/1753495X261456364","url":null,"abstract":"Background: Renal tubular acidosis (RTA) is a disorder of renal acid-base regulation causing normal anion gap metabolic acidosis. Among its three types, distal RTA (dRTA) is the most common form.Methods: This retrospective case series included pregnancies complicated by RTA managed at Fernandez Hospital, Hyderabad, India, between 2008 and 2024. Maternal and perinatal outcomes data were obtained from medical records.Results: Among 133,542 deliveries, 19 pregnancies were complicated by RTA, giving an incidence of 0.014%. All cases were Type I dRTA, with 84% secondary to connective tissue disorders, predominantly Sjögren's syndrome. Recurrent hypokalaemic periodic paralysis was the most common complication. With early diagnosis and meticulous metabolic correction, most women achieved term deliveries with favourable maternal and neonatal outcomes.Conclusions: Renal tubular acidosis in pregnancy may worsen due to physiological changes. Untreated disease poses risks from chronic acidosis and electrolyte imbalance. Early recognition and multidisciplinary management are crucial for optimal outcomes.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261456364"},"PeriodicalIF":0.5,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refractory hypokalemic metabolic alkalosis in pregnancy: Interplay of hyperemesis gravidarum and primary hyperparathyroidism. 妊娠期难治性低钾代谢性碱中毒：妊娠剧吐和原发性甲状旁腺功能亢进的相互作用。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-22 DOI: 10.1177/1753495X261439643

Anja Reichelt, Sarah Halmer, Emanuel Rotteneder, Anton Staudenherz, Susanne Schubert, Birgit Pfaller

引用次数: 0

A woman with homozygous familial hypercholesterolaemia requiring lipoprotein apheresis and coronary artery bypass graft in pregnancy. 纯合子家族性高胆固醇血症妇女妊娠期需要脂蛋白分离和冠状动脉旁路移植术。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-22 DOI: 10.1177/1753495X261448705

Stephanie Smith, Emad AlJaaly, Christopher Baker, Jaimini Cegla, Mandish Dhanjal, Sheba Jarvis, Naomi Primrose, Vinnie Sodhi, Shahenaz Walji, Charlotte J Frise

{"title":"A woman with homozygous familial hypercholesterolaemia requiring lipoprotein apheresis and coronary artery bypass graft in pregnancy.","authors":"Stephanie Smith, Emad AlJaaly, Christopher Baker, Jaimini Cegla, Mandish Dhanjal, Sheba Jarvis, Naomi Primrose, Vinnie Sodhi, Shahenaz Walji, Charlotte J Frise","doi":"10.1177/1753495X261448705","DOIUrl":"https://doi.org/10.1177/1753495X261448705","url":null,"abstract":"Homozygous familial hypercholesterolaemia (HoFH) is a rare condition characterised by markedly elevated low-density lipoprotein and early-onset atherosclerotic cardiovascular disease. Described here is a woman with HoFH and premature ischaemic heart disease who presented during her first pregnancy with poorly-controlled hyperlipidaemia. Despite ongoing treatment with lipid-lowering therapy and lipoprotein apheresis, she developed exertional angina at 17 weeks' gestation and was diagnosed with multi-vessel coronary artery disease. She underwent successful off-pump coronary artery bypass grafting at 19 weeks. She made a good recovery and the rest of her pregnancy progressed well, with delivery of a healthy infant at 37 weeks following emergency caesarean section. This case highlights the high cardiovascular risk associated with HoFH in pregnancy and the importance of multi-disciplinary management, including consideration of lipid-lowering therapy, lipoprotein apheresis and surgical intervention.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261448705"},"PeriodicalIF":0.5,"publicationDate":"2026-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13197336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report of miliary tuberculosis diagnosed in the peripartum period. 围生期军人肺结核1例。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-19 DOI: 10.1177/1753495X261437725

Yuliya M Ashton, Catherine Nelson-Piercy, Karan Sampat

引用次数: 0

Comments on "The impact of COVID-19 on the management of hypertensive disorders of pregnancy: An assessment of quality of care and outcomes". 对“COVID-19对妊娠高血压疾病管理的影响：护理质量和结局评估”的评论。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-08 DOI: 10.1177/1753495X261447699

Ankur Sharma, Sushma Narsing Katkuri, Varshini Vadhithala, Arun Kumar, Sushma Verma, Dhanya Dedeepya

引用次数: 0

Preterm delivery and long-term maternal renal disease: A systematic review and meta-analysis. 早产和长期母亲肾脏疾病：一项系统回顾和荟萃分析。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-07 DOI: 10.1177/1753495X261445504

Emily Stocks, Maryam Abdelkarim, Megan Holness, Siobhan Quenby, Joshua Odendaal

{"title":"Preterm delivery and long-term maternal renal disease: A systematic review and meta-analysis.","authors":"Emily Stocks, Maryam Abdelkarim, Megan Holness, Siobhan Quenby, Joshua Odendaal","doi":"10.1177/1753495X261445504","DOIUrl":"https://doi.org/10.1177/1753495X261445504","url":null,"abstract":"Objectives: Little is known about the impact of premature delivery on maternal renal complications. This systematic review aimed to evaluate the association between earlier delivery and long-term renal health in the pregnant population.Methods: A comprehensive database search was performed. Eligible studies included cross-sectional and cohort studies that reported preterm and full-term deliveries and subsequent maternal chronic kidney disease. A random-effects meta-analysis was used to calculate the pooled effect estimates. The Newcastle-Ottawa scale was used to assess the risk of bias.Results: Nine studies met the inclusion criteria. Preterm delivery was associated with long-term maternal renal disease with a pooled odds ratio (OR = 1.82, 95% CI: 1.17-2.85, p = 0.01). A sensitivity analysis identifying outlier study, and the pooled OR excluding it (OR = 2.16, 95% CI, 2.06-2.62; p < 0. 001, I2 = 0.0%).Conclusion: Preterm delivery is associated with a significant risk of long-term maternal renal disease. This suggests the need for careful postnatal risk management in this population.Précis: Preterm delivery is associated with higher risk of long-term maternal renal disease, warranting targeted postnatal care and further research into underlying biological mechanisms and preventive strategies.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261445504"},"PeriodicalIF":0.5,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13153015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147870350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study. 在多种族妊娠糖尿病患者中，更严格的血糖指标对妊娠结局的影响：一项回顾性、单中心观察性研究。

IF 0.5

Obstetric Medicine Pub Date : 2026-05-04 DOI: 10.1177/1753495X261445509

Mohammed Sb Huda, Niki Margari, Nafisa Islam, Hannah Jaumdally, Kate Wiles, Rehan Khan, Peter Jacob, Elena Greco, Stamatina Iliodromiti, Anita Sanghi, Shakila Thangaratinam

{"title":"Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study.","authors":"Mohammed Sb Huda, Niki Margari, Nafisa Islam, Hannah Jaumdally, Kate Wiles, Rehan Khan, Peter Jacob, Elena Greco, Stamatina Iliodromiti, Anita Sanghi, Shakila Thangaratinam","doi":"10.1177/1753495X261445509","DOIUrl":"https://doi.org/10.1177/1753495X261445509","url":null,"abstract":"Aims: To determine the impact of tighter glycaemic targets for gestational diabetes.Methods: Retrospective data analysis before and after introducing tighter glucose targets.Results: In 2265 pregnancies there was no change in large-for-gestational age babies (Odds ratio (OR) 1.1; 95% Confidence interval (CI) 0.8-1.6) and macrosomia (OR 1.0; 95% CI 0.6-1.7) following tighter glucose targets. Gestational hypertension (OR 0.4; 95% CI 0.2-0.7), spontaneous vaginal birth (OR 0.6; 95% CI 0.4-0.9) reduced and pharmacological treatment increased (OR 2.2; 95% CI 1.7-2.8).Composite adverse neonatal outcome (perinatal death, shoulder dystocia, fracture, nerve palsy) (OR 0.6; CI 0.02-14.2 p = 0.76)), Apgar<7 at 5 min, neonatal hypoglycaemia, respiratory distress syndrome or neonatal unit admission did not change but neonatal jaundice was reduced (OR 0.4; 95% CI 0.2-0.8).Conclusions: Tighter glycaemic targets had no impact on large-for-gestational age babies or composite adverse neonatal outcomes. There was reduced spontaneous vaginal birth, gestational hypertension, neonatal jaundice and increased pharmacological treatment.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X261445509"},"PeriodicalIF":0.5,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0