Obstetric MedicinePub Date : 2023-09-01Epub Date: 2023-08-31DOI: 10.1177/1753495X231195702
Stephen E Lapinsky, Charlotte J Frise
{"title":"<i>Obstetric Medicine</i>, impact factors and publishing.","authors":"Stephen E Lapinsky, Charlotte J Frise","doi":"10.1177/1753495X231195702","DOIUrl":"10.1177/1753495X231195702","url":null,"abstract":"","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10360388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-10-19DOI: 10.1177/1753495X221133150
Anthony J Bleyer, Kendrah O Kidd, Adrienne H Williams, Emily Johnson, Victoria Robins, Lauren Martin, Abbigail Taylor, Alice Kim, Isai Bowline, Dervla M Connaughton, Carl D Langefeld, Martina Zivna, Stanislav Kmoch
{"title":"Maternal health and pregnancy outcomes in autosomal dominant tubulointerstitial kidney disease.","authors":"Anthony J Bleyer, Kendrah O Kidd, Adrienne H Williams, Emily Johnson, Victoria Robins, Lauren Martin, Abbigail Taylor, Alice Kim, Isai Bowline, Dervla M Connaughton, Carl D Langefeld, Martina Zivna, Stanislav Kmoch","doi":"10.1177/1753495X221133150","DOIUrl":"10.1177/1753495X221133150","url":null,"abstract":"<p><strong>Introduction: </strong>Autosomal dominant tubulointerstitial kidney disease (ADTKD) is an increasingly recognized cause of chronic kidney disease. ADTKD pregnancy outcomes have not previously been described.</p><p><strong>Methods: </strong>A cross-sectional survey was sent to women from ADTKD families.</p><p><strong>Results: </strong>Information was obtained from 85 afffected women (164 term pregnancies) and 23 controls (50 pregnancies). Only 16.5% of genetically affected women knew they had ADTKD during pregnancy. Eighteen percent of ADTKD mothers had hypertension during pregnancy versus 12% in controls (<i>p</i> = 0.54) and >40% in comparative studies of chronic kidney disease in pregnancy. Eleven percent of births of ADTKD mothers were <37 weeks versus 0 in controls (<i>p</i> < 0.0001). Cesarean section occurred in 19% of pregnancies in affected women versus 38% of unaffected individuals (<i>p</i> = 0.06). Only 12% of babies required a neonatal intensive care unit stay.</p><p><strong>Conclusions: </strong>ADTKD pregnancies had lower rates of hypertension during pregnancy versus other forms of chronic kidney disease, which may have contributed to good maternal and fetal outcomes.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maternal and fetal outcomes in pregnant patients with non-cirrhotic portal hypertension: A systematic review and meta-analysis.","authors":"Suprabhat Giri, Shradhanjali Sahoo, Sridhar Sundaram, Akash Shukla","doi":"10.1177/1753495X221143864","DOIUrl":"10.1177/1753495X221143864","url":null,"abstract":"<p><strong>Background: </strong>Concerned studies with respect to the outcome of pregnant patients with non-cirrhotic portal hypertension are limited. Thus, a systematic review and meta-analysis of the available literature was conducted.</p><p><strong>Methods: </strong>A literature search was conducted from 1999 to December 2021 for studies evaluating pregnancy outcomes in patients with non-cirrhotic portal hypertension.</p><p><strong>Results: </strong>Twelve studies were included in the meta-analysis. The pooled rate of variceal bleeding, ascites and severe anemia requiring blood transfusion were 9.6%, 2.3%, and 14.9%, respectively. The pooled rate of spontaneous miscarriage, gestational hypertension, delivery by cesarean section, and postpartum hemorrhage were 11.9%, 4.5%, 36.7%, and 4.7%, respectively. The pooled stillbirth rate was 2.5% and among the live births, the pooled rates of preterm birth, low birth weight, intensive care unit admission, and neonatal mortality were 21.6%, 18.7%, 15.5%, and 1.8%, respectively.</p><p><strong>Conclusion: </strong>Pregnancy in patients with non-cirrhotic portal hypertension is associated with increased maternal & fetal morbidity but mortality remains low.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-02-15DOI: 10.1177/1753495X221078695
R Sujithra Devi, Sathiya Priya, Manoranjitha Kumari, G Ramkumar, SreeRekha Jinkala, Dilip Kumar Maurya, Anish Keepanasseril
{"title":"Diagnostic challenges in cerebral tuberculoma presenting with seizures in pregnancy.","authors":"R Sujithra Devi, Sathiya Priya, Manoranjitha Kumari, G Ramkumar, SreeRekha Jinkala, Dilip Kumar Maurya, Anish Keepanasseril","doi":"10.1177/1753495X221078695","DOIUrl":"10.1177/1753495X221078695","url":null,"abstract":"<p><p>Tuberculoma is an uncommon presentation of tuberculosis and is found in regions with a high prevalence of tuberculosis. This is rarely diagnosed during pregnancy. The presentation can mimic other etiologies such as eclampsia or cerebral venous sinus thrombosis so the diagnosis can be challenging, particularly when presenting with seizures in pregnancy. Described here is a woman in her first pregnancy who presented with seizures mimicking eclampsia and was suspected to have a brain tumour on neuroimaging. She was diagnosed to have a intracerebral tuberculoma on histopathological examination following surgical decompression after delivery.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10655413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-01-13DOI: 10.1177/1753495X211067119
Ufuk Demirci, Esra Altan Erbilen, Elif Gülsüm Ümit, Cihan İnan, N Cenk Sayın, Ahmet Muzaffer Demir
{"title":"Successful pregnancy and delivery management in a patient with Bernard Soulier Syndrome.","authors":"Ufuk Demirci, Esra Altan Erbilen, Elif Gülsüm Ümit, Cihan İnan, N Cenk Sayın, Ahmet Muzaffer Demir","doi":"10.1177/1753495X211067119","DOIUrl":"10.1177/1753495X211067119","url":null,"abstract":"<p><p>Bernard Soulier Syndrome (BSS) is an inherited bleeding disorder characterized by macrothrombocytopenia and absence of ristocetin-induced platelet aggregation. Clinical findings vary from person to person. Most of the patients are diagnosed with muco-cutaneous bleeding such as purpura, epistaxis and gingival bleeding in early childhood. Few pregnant women with BSS are described in the literature. Management of thrombocytopenia during pregnancy and delivery requires a multidisciplinary approach. The family should be warned about the potentially life-threatening bleeding during pregnancy and the delivery and the decision about mode of delivery should be individualised, involving discussion with patient and multidisciplinary team.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-05-03DOI: 10.1177/1753495X221092603
Sophie Platts, Gavin Thomas, Rebecca Allen
{"title":"Managing a new diagnosis of interstitial lung disease in pregnancy.","authors":"Sophie Platts, Gavin Thomas, Rebecca Allen","doi":"10.1177/1753495X221092603","DOIUrl":"10.1177/1753495X221092603","url":null,"abstract":"<p><p>Interstitial lung disease (ILD) presents rarely in pregnancy. Reports have associated disease activity with higher rates of preeclampsia, preterm births and fetal loss. This case report describes a patient presenting in her fifth pregnancy with worsening dyspnoea. She was treated with tacrolimus, prednisolone and post-partum methylprednisolone and ultimately had a successful outcome of childbirth.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-02-09DOI: 10.1177/1753495X221078440
Louise Carlson-Hedges, Arani Pillai
{"title":"A case series of severe symptomatic peripartum hyponatraemia.","authors":"Louise Carlson-Hedges, Arani Pillai","doi":"10.1177/1753495X221078440","DOIUrl":"10.1177/1753495X221078440","url":null,"abstract":"<p><p>This single centre case series describes the presentation and management of six cases of peripartum hyponatraemia in women who were otherwise deemed low-risk at delivery. It highlights presenting symptoms such as fatigue, confusion and seizures as well as the effects on the neonate. It also focuses on areas of interest such as fluid intake, hormonal effects of ADH and oxytocin and the association with birthing pools for future research.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-09-15DOI: 10.1177/1753495X221118433
Swaraj N Pande, Hemachandren Munuswamy, Durga P Rath, Sreevathsa Ks Prasad, Jyoti Baghel, Ajith A Pillai, Satyen Parida, Nivedita Mondal, Anish Keepanasseril
{"title":"Concurrent valve replacement and caesarean section for rheumatic mitral valve disease with refractory heart failure in late pregnancy.","authors":"Swaraj N Pande, Hemachandren Munuswamy, Durga P Rath, Sreevathsa Ks Prasad, Jyoti Baghel, Ajith A Pillai, Satyen Parida, Nivedita Mondal, Anish Keepanasseril","doi":"10.1177/1753495X221118433","DOIUrl":"10.1177/1753495X221118433","url":null,"abstract":"<p><strong>Objective: </strong>To assess clinical characteristics and outcomes of women who underwent concurrent valve replacement with caesarean section for severe rheumatic mitral valve disease with refractory heart failure.</p><p><strong>Methods: </strong>All women admitted to a single centre from 2011 to 2020 with severe rheumatic mitral valve disease, having recurrent episodes of pulmonary edema on optimal medical therapy and contraindication to percutaneous balloon mitral valvotomy, who underwent concurrent valve replacement (for native valve disease) along with caesarean section, were included.</p><p><strong>Results: </strong>Among 1300 pregnancies with rheumatic heart disease, six underwent the concurrent procedure. All had replacement of mitral valve except one who had both aortic and mitral valve replacements, between 33 and 39 weeks of gestation. There were no maternal deaths, and there was one neonatal loss from late-onset sepsis.</p><p><strong>Conclusion: </strong>Pregnant women with severe rheumatic mitral valve disease with refractory heart failure, unsuitable for minimal access interventions, can be considered for a concurrent valve replacement with caesarean section.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10311483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Al-Bakri, Mary Malebranche, Nabha Shetty, Ashley Miller, Kyle McCoy, Christopher M Nash
{"title":"Swyer-James-MacLeod syndrome in pregnancy: A case report.","authors":"Omar Al-Bakri, Mary Malebranche, Nabha Shetty, Ashley Miller, Kyle McCoy, Christopher M Nash","doi":"10.1177/1753495X221092601","DOIUrl":"https://doi.org/10.1177/1753495X221092601","url":null,"abstract":"<p><p>Scant literature is available regarding pregnancy outcomes in women with Swyer-James-MacLeod syndrome, a rare obstructive lung disease. We present a case of a woman with this syndrome in pregnancy. Her baseline pulmonary function tests (PFT) demonstrated moderate airflow obstruction however she had excellent functional status and exercise tolerance. Her disease remained clinically stable in pregnancy. PFTs demonstrated slight worsening of her obstruction with forced expiratory volume in one second (FEV1). 59% and FEV1/FVC ratio 64%. She was diagnosed with gestational diabetes requiring metformin and insulin. Her labor and delivery was uncomplicated with vaginal delivery of a live male at term with no maternal respiratory complications. She did have a delayed postpartum hemorrhage requiring a D&C procedure. This case report demonstrates women with Swyer-James-MacLeod syndrome can have a successful pregnancy and need not avoid pregnancy if desired.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/78/10.1177_1753495X221092601.PMC10504879.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10655419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-05-12DOI: 10.1177/1753495X221099443
Katherine Creeper, Dorothy Graham
{"title":"Crigler-Najjar type II in pregnancy: A case report.","authors":"Katherine Creeper, Dorothy Graham","doi":"10.1177/1753495X221099443","DOIUrl":"10.1177/1753495X221099443","url":null,"abstract":"<p><p>Crigler-Najjar is a rare, autosomal recessive disorder that results in mutations causing a complete absence (type I) or deficiency (type II) of the hepatic uridine diphospho-glucuronosyl transferase (UDPGT) enzyme. Both forms, however, result in unconjugated hyperbilirubinaemia which can lead to kernicterus and potentially death. Phenobarbitone can be used as an enzyme inducer in Type II to facilitate a reduction in total serum bilirubin. We report two consecutive pregnancies in a 29-year-old woman with Crigler-Najjar Type II syndrome. Phenobarbitone therapy was commenced in the first pregnancy at 16 weeks' gestation and was associated with favorable biochemical and clinical outcomes. There were no reports of long-term neonatal neurological sequelae. Tertiary center, multidisciplinary care is recommended for optimal pregnancy outcomes.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}