Obstetric Medicine最新文献_第10页

Contemporary pregnancy outcomes for women with moderate and severe congenital heart disease. 患有中度和重度先天性心脏病妇女的当代妊娠结局。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2021-12-09 DOI: 10.1177/1753495X211064458

Samantha A Kops, Danielle D Strah, Jennifer Andrews, Scott E Klewer, Michael D Seckeler

{"title":"Contemporary pregnancy outcomes for women with moderate and severe congenital heart disease.","authors":"Samantha A Kops, Danielle D Strah, Jennifer Andrews, Scott E Klewer, Michael D Seckeler","doi":"10.1177/1753495X211064458","DOIUrl":"10.1177/1753495X211064458","url":null,"abstract":"Background: Women with congenital heart disease (CHD) are surviving into adulthood, with more undergoing pregnancy.Methods: Retrospective review of the Vizient database from 2017-2019 for women 15-44 years old with moderate, severe or no CHD and vaginal delivery or caesarean section. Demographics, hospital outcomes and costs were compared.Results: There were 2,469,117 admissions: 2,467,589 with no CHD, 1277 with moderate and 251 with severe CHD. Both CHD groups were younger than no CHD, there were fewer white race/ethnicity in the no CHD group and more women with Medicare in both CHD groups compared to no CHD. With increasing CHD severity there was an increase in length of stay, ICU admission rates and costs. There were also higher rates of complications, mortality and caesarean section in the CHD groups.Conclusion: Pregnant women with CHD have more problematic pregnancies and understanding this impact is important to improve management and decrease healthcare utilization.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 1","pages":"17-22"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9779819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperventilation imitating preeclampsia. 模仿子痫前期的过度换气。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2021-12-13 DOI: 10.1177/1753495X211064142

Adam Morton

引用次数: 0

Maternal history of childhood maltreatment is associated with diurnal cortisol and DNA methylation of placental 11-beta-hydroxysteroid dehydrogenase type 2. 母亲的童年虐待史与昼夜皮质醇和胎盘 11-beta-羟基类固醇脱氢酶 2 型的 DNA 甲基化有关。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2022-03-18 DOI: 10.1177/1753495X221087168

Margaret Bublitz, Karl Kelsey, Rondi Butler, Ghada Bourjeily

{"title":"Maternal history of childhood maltreatment is associated with diurnal cortisol and DNA methylation of placental 11-beta-hydroxysteroid dehydrogenase type 2.","authors":"Margaret Bublitz, Karl Kelsey, Rondi Butler, Ghada Bourjeily","doi":"10.1177/1753495X221087168","DOIUrl":"10.1177/1753495X221087168","url":null,"abstract":"Background: Accumulating evidence indicates that maternal hypothalamic-pituitary-adrenal (HPA) axis activity over pregnancy differs according to maternal history of childhood maltreatment. DNA methylation of the placental 11-beta-hydroxysteroid dehydrogenase (BHSD) type 2 enzyme regulates fetal exposure to maternal cortisol, yet the association between maternal history of childhood maltreatment and methylation of placental 11BHSD type 2 has not been previously studied.Methods: We examined if maternal cortisol production at 11 and 32 weeks' gestation (n = 89) and placental methylation of the 11BHSD type 2 gene (n = 19) differed among pregnant women with and without histories of childhood maltreatment. Twenty-nine percent of participants reported a history of childhood maltreatment (physical/sexual abuse).Results: Women with histories of childhood maltreatment displayed lower cortisol in early gestation, hypo-methylation of placental 11BHSD type 2, and lower levels of cord blood cortisol.Conclusion: Preliminary results suggest alterations in cortisol regulation over pregnancy according to maternal history of childhood maltreatment.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 1","pages":"12-16"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9466802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pregnancy in a woman with congenital adrenal hyperplasia with 11-beta-hydroxylase deficiency: A case report. 先天性肾上腺皮质增生症伴有 11-beta-hydroxylase 缺乏症的妇女怀孕了：病例报告。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2021-09-24 DOI: 10.1177/1753495X211042729

Kavitha Krishnan, Silja Pillai, Gowri Vaidyanathan

{"title":"Pregnancy in a woman with congenital adrenal hyperplasia with 11-beta-hydroxylase deficiency: A case report.","authors":"Kavitha Krishnan, Silja Pillai, Gowri Vaidyanathan","doi":"10.1177/1753495X211042729","DOIUrl":"10.1177/1753495X211042729","url":null,"abstract":"Background: Successful pregnancy with congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency is an extremely rare condition. Only two cases have been reported in the literature.Methods and results: Described here is a 30-year-old woman diagnosed as a neonate with congenital adrenal hyperplasia related to 11-beta-hydroxylase deficiency classic type, who subsequently underwent clitoral resection and vaginoplasty. She was started on lifelong steroid therapy after surgery. She developed hypertension at 11 years of age and was on antihypertensive therapy from then on. In later life, she underwent division of vaginal scar tissue and perineal refashioning. She spontaneously conceived but her pregnancy was complicated by severe pre-eclampsia and delivery was required at 33 weeks of gestation by cesarean section. A healthy male infant was delivered.Conclusion: Management of these women is similar to those with more common causes of congenital adrenal hyperplasia, with careful monitoring throughout pregnancy for complications such as gestational diabetes, gestational hypertension, and intrauterine growth restriction.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 1","pages":"66-68"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9779815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Walking the walk to include pregnant participants in non-obstetric clinical trials: Insights from the SNAP Trial. 让孕妇参与非产科临床试验：SNAP试验的启示。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2023-03-22 DOI: 10.1177/1753495X231163351

Isabelle Malhamé, Erica Hardy, Matthew P Cheng, Steven Yc Tong, Asha C Bowen

引用次数: 0

Possible additional criteria for the diagnosis of preeclampsia with severe features. 诊断具有严重特征的子痫前期的可能附加标准。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2022-05-26 DOI: 10.1177/1753495X221103981

Adam Morton

引用次数: 0

Optimal management of post-discharge postpartum hypertensive disorders of pregnancy: a quality improvement initiative. 出院后妊娠高血压疾病的优化管理：质量改进计划。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2022-02-10 DOI: 10.1177/1753495X221074613

Alexia Tanguay Lecomte, Lauriane Vittoz, Nadine Sauvé, Marie-Ève Roy-Lacroix, Mandy Malick, Anne-Marie Côté

{"title":"Optimal management of post-discharge postpartum hypertensive disorders of pregnancy: a quality improvement initiative.","authors":"Alexia Tanguay Lecomte, Lauriane Vittoz, Nadine Sauvé, Marie-Ève Roy-Lacroix, Mandy Malick, Anne-Marie Côté","doi":"10.1177/1753495X221074613","DOIUrl":"10.1177/1753495X221074613","url":null,"abstract":"Introduction: Postpartum hypertensive disorders of pregnancy occur in 2-5% of pregnancies. It is a major cause of urgent postpartum consultation and is associated with life-threatening complications. Our objective was to evaluate if local management of postpartum hypertensive disorders of pregnancy was congruent with expert recommendations. Methods: We conducted a quality improvement initiative through a retrospective single-centre cross-sectional study. All women over 18-year-old consulting emergently for hypertensive disorders of pregnancy in the first six weeks postpartum, from 2015 to 2020, were eligible. Results: We included 224 women. Optimal management of postpartum hypertensive disorders of pregnancy was observed in 65.0%. While diagnosis and laboratory work-up were excellent, adequate blood pressure surveillance and recommendations upon discharge of an outpatient postpartum episode (69.7%) did not meet expectations. Conclusion: Efforts should be targeted to improve discharge recommendations on optimal blood pressure surveillance after delivery for women at risk for hypertensive disorders of pregnancy and for postpartum hypertensive disorders of pregnancy in women treated as outpatients.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 1","pages":"29-34"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9763526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe tachypnoea and dyspnoea due to physiological hyperventilation in pregnancy. 妊娠期生理性过度换气导致的严重呼吸急促和呼吸困难。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2021-08-31 DOI: 10.1177/1753495X211037885

Brady Thomson, Ragani Velusamy, Annabel Martin

引用次数: 0

Pregnancy-associated haemolytic anaemia: A cause not to be forgotten. 妊娠相关性溶血性贫血：不容忽视的原因。

IF 0.7

Obstetric Medicine Pub Date : 2023-03-01 Epub Date: 2021-11-20 DOI: 10.1177/1753495X211045337

Katherine Creeper, Dorothy Graham

引用次数: 0

Idiopathic orbital myositis in a pregnant woman. 一名孕妇的特发性眼眶肌炎