Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-02-15DOI: 10.1177/1753495X221078695
R Sujithra Devi, Sathiya Priya, Manoranjitha Kumari, G Ramkumar, SreeRekha Jinkala, Dilip Kumar Maurya, Anish Keepanasseril
{"title":"Diagnostic challenges in cerebral tuberculoma presenting with seizures in pregnancy.","authors":"R Sujithra Devi, Sathiya Priya, Manoranjitha Kumari, G Ramkumar, SreeRekha Jinkala, Dilip Kumar Maurya, Anish Keepanasseril","doi":"10.1177/1753495X221078695","DOIUrl":"10.1177/1753495X221078695","url":null,"abstract":"<p><p>Tuberculoma is an uncommon presentation of tuberculosis and is found in regions with a high prevalence of tuberculosis. This is rarely diagnosed during pregnancy. The presentation can mimic other etiologies such as eclampsia or cerebral venous sinus thrombosis so the diagnosis can be challenging, particularly when presenting with seizures in pregnancy. Described here is a woman in her first pregnancy who presented with seizures mimicking eclampsia and was suspected to have a brain tumour on neuroimaging. She was diagnosed to have a intracerebral tuberculoma on histopathological examination following surgical decompression after delivery.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"192-195"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10655413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-01-13DOI: 10.1177/1753495X211067119
Ufuk Demirci, Esra Altan Erbilen, Elif Gülsüm Ümit, Cihan İnan, N Cenk Sayın, Ahmet Muzaffer Demir
{"title":"Successful pregnancy and delivery management in a patient with Bernard Soulier Syndrome.","authors":"Ufuk Demirci, Esra Altan Erbilen, Elif Gülsüm Ümit, Cihan İnan, N Cenk Sayın, Ahmet Muzaffer Demir","doi":"10.1177/1753495X211067119","DOIUrl":"10.1177/1753495X211067119","url":null,"abstract":"<p><p>Bernard Soulier Syndrome (BSS) is an inherited bleeding disorder characterized by macrothrombocytopenia and absence of ristocetin-induced platelet aggregation. Clinical findings vary from person to person. Most of the patients are diagnosed with muco-cutaneous bleeding such as purpura, epistaxis and gingival bleeding in early childhood. Few pregnant women with BSS are described in the literature. Management of thrombocytopenia during pregnancy and delivery requires a multidisciplinary approach. The family should be warned about the potentially life-threatening bleeding during pregnancy and the delivery and the decision about mode of delivery should be individualised, involving discussion with patient and multidisciplinary team.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"203-205"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-05-03DOI: 10.1177/1753495X221092603
Sophie Platts, Gavin Thomas, Rebecca Allen
{"title":"Managing a new diagnosis of interstitial lung disease in pregnancy.","authors":"Sophie Platts, Gavin Thomas, Rebecca Allen","doi":"10.1177/1753495X221092603","DOIUrl":"10.1177/1753495X221092603","url":null,"abstract":"<p><p>Interstitial lung disease (ILD) presents rarely in pregnancy. Reports have associated disease activity with higher rates of preeclampsia, preterm births and fetal loss. This case report describes a patient presenting in her fifth pregnancy with worsening dyspnoea. She was treated with tacrolimus, prednisolone and post-partum methylprednisolone and ultimately had a successful outcome of childbirth.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"189-191"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-02-09DOI: 10.1177/1753495X221078440
Louise Carlson-Hedges, Arani Pillai
{"title":"A case series of severe symptomatic peripartum hyponatraemia.","authors":"Louise Carlson-Hedges, Arani Pillai","doi":"10.1177/1753495X221078440","DOIUrl":"10.1177/1753495X221078440","url":null,"abstract":"<p><p>This single centre case series describes the presentation and management of six cases of peripartum hyponatraemia in women who were otherwise deemed low-risk at delivery. It highlights presenting symptoms such as fatigue, confusion and seizures as well as the effects on the neonate. It also focuses on areas of interest such as fluid intake, hormonal effects of ADH and oxytocin and the association with birthing pools for future research.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"196-199"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-09-15DOI: 10.1177/1753495X221118433
Swaraj N Pande, Hemachandren Munuswamy, Durga P Rath, Sreevathsa Ks Prasad, Jyoti Baghel, Ajith A Pillai, Satyen Parida, Nivedita Mondal, Anish Keepanasseril
{"title":"Concurrent valve replacement and caesarean section for rheumatic mitral valve disease with refractory heart failure in late pregnancy.","authors":"Swaraj N Pande, Hemachandren Munuswamy, Durga P Rath, Sreevathsa Ks Prasad, Jyoti Baghel, Ajith A Pillai, Satyen Parida, Nivedita Mondal, Anish Keepanasseril","doi":"10.1177/1753495X221118433","DOIUrl":"10.1177/1753495X221118433","url":null,"abstract":"<p><strong>Objective: </strong>To assess clinical characteristics and outcomes of women who underwent concurrent valve replacement with caesarean section for severe rheumatic mitral valve disease with refractory heart failure.</p><p><strong>Methods: </strong>All women admitted to a single centre from 2011 to 2020 with severe rheumatic mitral valve disease, having recurrent episodes of pulmonary edema on optimal medical therapy and contraindication to percutaneous balloon mitral valvotomy, who underwent concurrent valve replacement (for native valve disease) along with caesarean section, were included.</p><p><strong>Results: </strong>Among 1300 pregnancies with rheumatic heart disease, six underwent the concurrent procedure. All had replacement of mitral valve except one who had both aortic and mitral valve replacements, between 33 and 39 weeks of gestation. There were no maternal deaths, and there was one neonatal loss from late-onset sepsis.</p><p><strong>Conclusion: </strong>Pregnant women with severe rheumatic mitral valve disease with refractory heart failure, unsuitable for minimal access interventions, can be considered for a concurrent valve replacement with caesarean section.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"156-161"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10311483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Al-Bakri, Mary Malebranche, Nabha Shetty, Ashley Miller, Kyle McCoy, Christopher M Nash
{"title":"Swyer-James-MacLeod syndrome in pregnancy: A case report.","authors":"Omar Al-Bakri, Mary Malebranche, Nabha Shetty, Ashley Miller, Kyle McCoy, Christopher M Nash","doi":"10.1177/1753495X221092601","DOIUrl":"https://doi.org/10.1177/1753495X221092601","url":null,"abstract":"<p><p>Scant literature is available regarding pregnancy outcomes in women with Swyer-James-MacLeod syndrome, a rare obstructive lung disease. We present a case of a woman with this syndrome in pregnancy. Her baseline pulmonary function tests (PFT) demonstrated moderate airflow obstruction however she had excellent functional status and exercise tolerance. Her disease remained clinically stable in pregnancy. PFTs demonstrated slight worsening of her obstruction with forced expiratory volume in one second (FEV1). 59% and FEV1/FVC ratio 64%. She was diagnosed with gestational diabetes requiring metformin and insulin. Her labor and delivery was uncomplicated with vaginal delivery of a live male at term with no maternal respiratory complications. She did have a delayed postpartum hemorrhage requiring a D&C procedure. This case report demonstrates women with Swyer-James-MacLeod syndrome can have a successful pregnancy and need not avoid pregnancy if desired.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"187-188"},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/78/10.1177_1753495X221092601.PMC10504879.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10655419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-02-11DOI: 10.1177/1753495X221078447
Christina Coroyannakis, Maite Tome, Ingrid Watt-Coote, Matthew Cauldwell
{"title":"Pregnancy following personalised aortic root support in Marfan syndrome.","authors":"Christina Coroyannakis, Maite Tome, Ingrid Watt-Coote, Matthew Cauldwell","doi":"10.1177/1753495X221078447","DOIUrl":"10.1177/1753495X221078447","url":null,"abstract":"<p><p>Marfan syndrome (MFS) is linked with adverse pregnancy events, one of the most significant being aortic dissection. We present a case of a woman with MFS with prior aortic root dilatation who opted for a Personalised External Aortic Root Support (PEARS). To date, she is only the fifth woman to have had this valve-sparing procedure prior to pregnancy. We outline her care in a tertiary centre with multidisciplinary expertise, from preconception through to the postpartum period.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"200-202"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10672043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-12-25DOI: 10.1177/1753495X221146329
Heather Lawrence, Adam Morton
{"title":"Postpartum complications following neuraxial anaesthesia for obstetric physicians.","authors":"Heather Lawrence, Adam Morton","doi":"10.1177/1753495X221146329","DOIUrl":"10.1177/1753495X221146329","url":null,"abstract":"<p><p>Neuraxial analgesia and anaesthesia are widely accepted and well-tolerated modes of delivery analgesia, being employed in up to 76% of vaginal deliveries and 94% of caesarean deliveries in the United States.<sup>1</sup> A cause of considerable concern for postpartum women, their family and caring health professionals is the occurrence of unexplained postpartum complications, not only for management in the index pregnancy, but the uncertain risk of recurrence in future pregnancies. Complications of neuraxial blocks may impact significantly on the ability of mothers to care for and bond with their newborn. The reported incidence of temporary neurological deficit following obstetric neuraxial blocks is 1 in 3900 procedures, and the risk of permanent neurological harm estimated to be between 1 in 80,000 and 1 in 320,425 procedures.<sup>2</sup> Obstetric physicians may be asked to review women with postpartum complications following neuraxial blocks. This article reviews complications that may be seen following neuraxial blocks for delivery.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"142-150"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10307093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstetric MedicinePub Date : 2023-09-01Epub Date: 2022-05-12DOI: 10.1177/1753495X221099443
Katherine Creeper, Dorothy Graham
{"title":"Crigler-Najjar type II in pregnancy: A case report.","authors":"Katherine Creeper, Dorothy Graham","doi":"10.1177/1753495X221099443","DOIUrl":"10.1177/1753495X221099443","url":null,"abstract":"<p><p>Crigler-Najjar is a rare, autosomal recessive disorder that results in mutations causing a complete absence (type I) or deficiency (type II) of the hepatic uridine diphospho-glucuronosyl transferase (UDPGT) enzyme. Both forms, however, result in unconjugated hyperbilirubinaemia which can lead to kernicterus and potentially death. Phenobarbitone can be used as an enzyme inducer in Type II to facilitate a reduction in total serum bilirubin. We report two consecutive pregnancies in a 29-year-old woman with Crigler-Najjar Type II syndrome. Phenobarbitone therapy was commenced in the first pregnancy at 16 weeks' gestation and was associated with favorable biochemical and clinical outcomes. There were no reports of long-term neonatal neurological sequelae. Tertiary center, multidisciplinary care is recommended for optimal pregnancy outcomes.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"184-186"},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of the COVID-19 pandemic on perinatal mental health screening, illness and pregnancy outcomes: A cohort study.","authors":"Andre C Q Lo, Michelle Kemp, Nikolett Kabacs","doi":"10.1177/1753495X221139565","DOIUrl":"https://doi.org/10.1177/1753495X221139565","url":null,"abstract":"<p><strong>Background: </strong>The aim was to explore the impact of the COVID-19 pandemic on perinatal mental health screening, illness and related pregnancy complications/outcomes.</p><p><strong>Methods: </strong>A single-centre retrospective cohort study in mothers giving birth before versus during the pandemic. Primary outcomes were the comparative prevalence/incidence of peripartum psychiatric diagnoses. Secondary outcomes were the pandemic's effect on psychiatric screening accuracy, and on other pregnancy outcomes linked to mental health.</p><p><strong>Results: </strong>The pandemic did not significantly increase the crude incidence of diagnosed peripartum anxiety (risk ratio (RR) = 1.39, 95% CI = 0.66-2.95), depression (RR = 1.63, 95% CI = 0.72-3.70) or other pregnancy outcomes. In multivariate models, the pandemic decreased Apgar scores and was involved in interaction effects for postpartum mental illness and birthweight. Psychiatric screening at the booking appointment exhibited lower sensitivity in predicting antenatal mental illness (pre-pandemic = 85.71%, pandemic = 25.00%; <i>p</i> = 0.035).</p><p><strong>Conclusions: </strong>The lowered screening sensitivity likely meant mental illness was poorly anticipated/under-detected during the pandemic, leading to no crude increase in perinatal psychiatric diagnoses.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"16 3","pages":"178-183"},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10311481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}