Holy Bezanahary, Jonathan Thiolon, François Dalmay, Jean-Luc Eyraud, Baher Youssef, Yves Aubard, Philippe Lacroix, Lucie Chastaingt, Perrine Coste-Mazeau
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引用次数: 0
摘要
背景：一些ABO血型可能是静脉血栓形成的危险因素。ABO血型与子痫前期风险之间的关系仍有争议。本研究的目的是评估先兆子痫与ABO血型之间的关系。方法：在前瞻性单中心登记中进行回顾性病例对照（1:2）研究，包括20171例妊娠。确定有先兆子痫和严重先兆子痫的妇女。对照组根据年龄、胎次、分娩年份和体重指数进行匹配。考虑了血型。结果：纳入病例253例，对照组506例。非o组（57.51% vs 62.56, p: 0.19）、A组（39.92% vs 44.05, p: 0.29）、B组（13.83% vs 15.42, p: 0.57）、AB组（3.75 vs 3.08, p: 0.64）病例与对照组之间分布无差异。分析扩展到严重的先兆子痫没有发现差异。结论：本研究未发现ABO血型与子痫前期风险之间的任何关系。
ABO blood group and risk of pre-eclampsia. A case-control study.
Background: It appears that some ABO blood groups may be a risk factor for venous thrombosis. The association between ABO group and risk of pre-eclampsia remains controversial. The purpose of this study was to evaluate the relationship between pre-eclampsia and ABO groups.
Methods: A retrospective case-control (1:2) study in a prospective monocentric registry including 20171 pregnancies was performed. Women with pre-eclampsia and severe pre-eclampsia were identified. Controls were matched according to age, parity, year of delivery and body mass index. Blood groups were considered.
Results: Two hundred fifty-three cases and 506 controls were included. No difference in distribution was found between cases and controls for non-O group (57.51% vs 62.56, p: 0.19), group A (39.92% vs 44.05, p: 0.29), group B (13.83% vs 15.42, p: 0.57) group AB (3.75 vs 3.08, p: 0.64). The analysis extended to severe pre-eclampsia showed no difference.
Conclusion: This study did not document any relationship between ABO groups and the risk of preeclampsia.
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