The Eurasian Journal of Medicine最新文献_第8页

Preprocedural Ultrasonography Versus Landmark-Guided Spinal Anesthesia in Geriatric Patients with Difficult Anatomy: A Prospective Randomized Trial. 术前超声检查与标志引导脊柱麻醉在老年解剖困难患者中的应用:一项前瞻性随机试验。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2021-02-01 Epub Date: 2020-11-23 DOI: 10.5152/eurasianjmed.2020.20215

Yasin Uyel, Alper Kilicaslan

{"title":"Preprocedural Ultrasonography Versus Landmark-Guided Spinal Anesthesia in Geriatric Patients with Difficult Anatomy: A Prospective Randomized Trial.","authors":"Yasin Uyel, Alper Kilicaslan","doi":"10.5152/eurasianjmed.2020.20215","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2020.20215","url":null,"abstract":"Objective: This study was aimed to determine whether preprocedural ultrasonography (USG) affects the technical performance of spinal anesthesia in elderly patients with difficulty in palpating landmarks, scoliosis, or previous spine surgery.Materials and methods: This prospective study was conducted in 156 elderly patients scheduled for elective orthopedic lower extremity surgery. The patients were randomly divided into 2 groups to receive spinal anesthesia by the preprocedural USG examination (group U) or conventional landmark palpation technique (group P). The primary finding of our study was the rate of successful access to the subarachnoid space on initial needle insertion attempt. Secondary achievements included number of needle insertion attempts, number of needle redirections, total procedure time, needle pain scores, patient satisfaction, and complications of spinal anesthesia.Results: The rate of successful access to the subarachnoid space at the first needle insertion attempt was significantly higher in group U than in group P (74.4% vs 53.8%, p=0.008). Medians (interquartile range) of both needle insertion attempts (group P, 2 [1-3] vs group U, 1 [1-2]; p=0.038) and needle redirections (group P, 3 [2-5] vs group U, 2 [1-4]; p=0.028), requiring to achieve dural puncture, were significantly higher among the patients in group P than those in group U. No statistically significant difference was found between the groups regarding total procedure time, pain scores, patient satisfaction scores, and spinal anesthesia-induced complications (p>0.05).Conclusion: Our study findings showed that preprocedural neuroaxial USG improves technical performance of spinal anesthesia in elderly patients with difficult anatomy.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":" ","pages":"9-14"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929581/pdf/eajm-53-1-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25476011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Effect of Inspiratory Muscle Training with Royal Jelly Supplement on Iron Metabolism in Cigarette Addicts. 补充蜂王浆吸入肌训练对烟瘾患者铁代谢的影响。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2021-02-01 Epub Date: 2021-01-19 DOI: 10.5152/eurasianjmed.2020.20271

Zarife Pancar

{"title":"Effect of Inspiratory Muscle Training with Royal Jelly Supplement on Iron Metabolism in Cigarette Addicts.","authors":"Zarife Pancar","doi":"10.5152/eurasianjmed.2020.20271","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2020.20271","url":null,"abstract":"Objective: The strength or weakness of the respiratory muscles compared with other skeletal muscles owing to their more specialized structures is considered as an indicator or cause of a disease. This study aimed to investigate the effects of inspiratory muscle training with royal jelly (RJ) supplement on iron metabolism in cigarette addicts.Materials and methods: A total of 40 male volunteers participated in the study who were divided into 4 groups before the study as follows: smoker control group (n=10), inspiratory muscle training (IMT) group (n=10), RJ group (n=10), and RJ+IMT (n=10) group. Blood samples were taken from all the participants for analysis of iron, iron binding, and total iron binding capacity. Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) measurements for the groups to perform training were carried out with 40% of their MIP values. The training sessions were carried out at the same time every day for 4 weeks (5 days per week).Results: The Statistical Package for Social Sciences version 22.0 program was used for statistical analyses. The results of the analysis found that the iron, iron binding, and total iron binding capacities were in favor of post-tests in the RJ supplement IMT, and RJ+IMT groups compared with those in the control group (p<0.05). There was a statistically significant difference between the RJ supplement, IMT, and RJ+IMT groups compared with the control group (p<0.05).Conclusion: Therefore, it could be concluded that the IMT and RJ supplements positively affected these parameters by altering the iron metabolism of the cigarette addicts.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":" ","pages":"15-18"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929577/pdf/eajm-53-1-15.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25476012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Thoracic Magnetic Resonance Imaging Applications in Children". “胸部磁共振成像在儿童中的应用”述评。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2021-02-01 DOI: 10.5152/eurasianjmed.2021.20121

Marco Maglione, Melissa Borrelli, Francesca Santamaria

{"title":"Comment on \"Thoracic Magnetic Resonance Imaging Applications in Children\".","authors":"Marco Maglione, Melissa Borrelli, Francesca Santamaria","doi":"10.5152/eurasianjmed.2021.20121","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2021.20121","url":null,"abstract":"We deeply commend Adem Karaman on his effort in summarizing the current applications of chest magnetic resonance imaging (MRI) in children in a recent issue of The Eurasian Journal of Medicine (February 2020) [1]. This is an area that we actively pursued in noncystic fibrosis chronic respiratory disorders, showing that such a technique represents a reliable radiation-free alternative to computed tomography (CT) in assessing the extent and severity of lung abnormalities in conditions including primary ciliary dyskinesia, immune defects, and recurrent pneumonia [2]. In these patients, MRI allowed good to excellent visualization of bronchiectasis, consolidations, mucus plugging, and peribronchial wall thickening. Assessment of MRI performance outcomes in comparison with CT showed high sensitivity and specificity for the detection of most lung abnormalities. However, because of its low proton density, air is poorly visualized at MRI, and therefore, worse performance outcomes were detected for bullae and emphysema, owing to the increased air content typical of these lesions [3].","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":" ","pages":"62-63"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929584/pdf/eajm-53-1-62.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25477475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Dose Vitamin C Infusion for the Treatment of Covid-19: Beware of Paraben Intoxication. 大剂量维生素C输注治疗Covid-19:小心对羟基苯甲酸酯中毒。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2021-02-01 Epub Date: 2021-01-19 DOI: 10.5152/eurasianjmed.2020.20184

Mehmet Eren Yuksel, Seval Izdes

{"title":"High-Dose Vitamin C Infusion for the Treatment of Covid-19: Beware of Paraben Intoxication.","authors":"Mehmet Eren Yuksel, Seval Izdes","doi":"10.5152/eurasianjmed.2020.20184","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2020.20184","url":null,"abstract":"Vitamin C (ascorbic acid) has several favorable effects on the immune system, such as enhancing phagocyte function, interferon production, and T-lymphocyte transformation [1]. Moreover, vitamin C diminishes inflammation and lung injury by reducing hydrogen peroxide, superoxide anion, and nitric oxide levels [2]. In addition, vitamin C was shown to increase the resistance of chick embryo ciliated tracheal organ cultures to Corona virus infection [3]. Furthermore, patients with severe pneumonia were treated with vitamin C infusion at a dose of 6 g/day and this treatment was found to be associated with lower mortality and improved chest radiologic score on the 7th day [2]. In the light of this information, a phase II clinical trial (NCT04264533) was initiated in China to evaluate the effect of high-dose intravenous (i.v.) vitamin C (24 g/day for 7 days) on intensive care unit (ICU) patients with severe Corona virus disease-19 (Covid19)-associated pneumonia [4]. Nevertheless, this study has not been completed yet. Inspired by these studies, we considered administration of high-dose vitamin C for the treatment of ICU patients with severe Covid-19 pneumonia. However, as soon as we noticed the paraben component (methylparaben 4 mg, propylparaben 0.5 mg) in 500 mg i.v. vitamin C preparation in our country, we refrained from the administration of this medication. Since the content of this vitamin C preparation is adjusted to the daily recommended dosage (100-300 mg), paraben accumulation may occur when a high dose of vitamin C is administered to patients.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":" ","pages":"69"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929582/pdf/eajm-53-1-69.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25475904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editor's Recognition Awards and acknowledgements. 编辑嘉许奖及致谢。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2021-02-01

引用次数: 0

Can Beaver Tail Liver be the Cause of Preference in Living Liver Transplantation Donors? 海狸尾肝会成为活体肝移植供者偏好的原因吗?

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2021-02-01 DOI: 10.5152/eurasianjmed.2021.21002

Bahar Yilmaz Cankaya

{"title":"Can Beaver Tail Liver be the Cause of Preference in Living Liver Transplantation Donors?","authors":"Bahar Yilmaz Cankaya","doi":"10.5152/eurasianjmed.2021.21002","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2021.21002","url":null,"abstract":"Objective: This study aims to investigate whether there was a difference between the levels of safety in terms of the postoperative residual liver volume in living transplant donors with normal liver anatomy and beaver tail liver.Materials and methods: Contrast-enhanced abdominal computed tomography (CT) images of 158 volunteers were retrospectively scanned. They were divided into 2 groups; with and without beaver tail liver. The total and left lobe volumes of the liver in all the candidates were calculated. The data were evaluated using the Mann-Whitney U test. Statistical values of p<0.05 were considered significant.Results: The median value of the total liver volume was 1.252 mL and that of the left lobe percentage was 38% in the beaver tail group and 1.375 mL and 35%, respectively, in the normal liver group. A significant difference was observed in terms of the total liver volume and left lobe volume percentages of the 2 groups (p=0.012 and p<0.001, respectively).Conclusion: The percentage of the left lobe in the beaver tail group was significantly higher, which indicates that liver transplantation donors with the beaver tail feature may be safer in terms of residual liver volume.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":" ","pages":"53-56"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929591/pdf/eajm-53-1-53.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25477473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Protective Roles of Butein on Indomethacin Induced Gastric Ulcer in Mice. 丁胺素对吲哚美辛致小鼠胃溃疡的保护作用。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2020-10-01 DOI: 10.5152/eurasianjmed.2020.20022

Rustem Anil Ugan, Harun Un

{"title":"The Protective Roles of Butein on Indomethacin Induced Gastric Ulcer in Mice.","authors":"Rustem Anil Ugan, Harun Un","doi":"10.5152/eurasianjmed.2020.20022","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2020.20022","url":null,"abstract":"Objective: Butein is a potential agent first isolated from Rhus verniciflua that has medicinal value in East Asia and has been used in the treatment of gastritis, gastric cancer, and atherosclerosis since ancient times. The aim of our study is to show, for the first time, the anti-ulcerative effect of butein in indomethacin induced gastric ulcer in mice.Materials and methods: A total of 42 mice were fasted 24 hours for the ulcer experiment, and 10, 20, and 40 mg/kg doses of butein were evaluated for their antiulcer activity. Famotidine 40 mg/kg was used as a positive control group. For ulcer induction, 25 mg/kg dose of indomethacin was administered to the mice and after 6 hours all stomachs were dissected out. After macroscopic analyses, tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), COX-1, and COX-2 mRNA levels of stomachs were evaluated by Real Time PCR, and Superoxide dismutase (SOD), glutathione (GSH), and malondialdehyde (MDA) were determined by ELISA.Results: Butein administration exerted 50.8%, 65.9%, and 87.1% antiulcer effects at 10, 20, and 40 mg/kg, respectively. Butein administration decreased oxidative stress and inflammatory parameters in stomach tissues dose dependently. Furthermore, butein administration increased stomach PGE2 levels and decreased COX-1 and COX-2 mRNA levels.Conclusion: Butein has been shown to have a healing effect on ulcers in macroscopic examinations in our study. We observed that butein has antioxidant and anti-cytokine properties in gastric tissue. Butein could be an important alternative in the treatment of indomethacin-induced ulcers. Whether butein is a partial agonist of the COX enzyme should be investigated in future studies.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":"52 3","pages":"265-270"},"PeriodicalIF":1.5,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651756/pdf/eajm-52-3-265.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38627577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Absence of GATA4 Mutations in Moroccan Patients with Atrial Septal Defect (ASD) Provides Further Evidence of Limited Involvement of GATA4 in Major Congenital Heart Defects. 摩洛哥房间隔缺损(ASD)患者中没有GATA4突变，这进一步证明了GATA4在主要先天性心脏缺陷中的作用有限。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2020-10-01 DOI: 10.5152/eurasianjmed.2020.19237

Ihssane El Bouchikhi, Laila Bouguenouch, Fatima Zohra Moufid, Khadija Belhassan, Imane Samri, Amal Chaouti, Mohammed Iraqui Houssaïni, Samir Atmani, Karim Ouldim

{"title":"Absence of GATA4 Mutations in Moroccan Patients with Atrial Septal Defect (ASD) Provides Further Evidence of Limited Involvement of GATA4 in Major Congenital Heart Defects.","authors":"Ihssane El Bouchikhi, Laila Bouguenouch, Fatima Zohra Moufid, Khadija Belhassan, Imane Samri, Amal Chaouti, Mohammed Iraqui Houssaïni, Samir Atmani, Karim Ouldim","doi":"10.5152/eurasianjmed.2020.19237","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2020.19237","url":null,"abstract":"Objective: Atrial septal defect (ASD) is one of the most common types of congenital heart disease (CHD). It is mainly caused by mutations of NK2 homeobox 5, GATA binding protein 4 (GATA4), and myosin heavy chain 6 in non-syndromic cases. This study aims to carry out, for the first time, the GATA4 mutation screening in a Moroccan population affected by ASD and compare the obtained mutation rate across populations.Materials and methods: A total of 33 patients were enrolled in this study. DNAs were extracted from peripheral blood samples, and we performed PCR-sequencing for GATA4 coding regions. Sequences were analyzed by sequence alignment and functional impact prediction tools. Mutation rate comparisons were performed by R software using the appropriate statistical tests.Results: We detected 7 variants, but no pathogenic mutation was revealed, except for Asn352= that was assessed by human splicing finder algorithms to have a potential impairing effect on the splicing mechanism. Until proven by in vitro functional studies, the current pathogenic mutation rate in our cohort seems to be 0%. Statistical comparison with previous studies from all over the world shows no significant difference. Seemingly, comparison of previous GATA4 mutation rates among tetralogy of Fallot (TOF) populations shows no significant difference.Conclusion: The low rates of GATA4 mutations observed throughout ASD and TOF international populations may suggest a limited causality of GATA4 mutations in the main CHDs, which further confirms the co-involvement of additional genetic and/or environmental factors in the manifestation of these phenotypes.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":"52 3","pages":"283-287"},"PeriodicalIF":1.5,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651766/pdf/eajm-52-3-283.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38627580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Behçet's Disease: Different Systemic Manifestations at Different Ages. behaperet病:不同年龄的不同全身表现。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2020-10-01 Epub Date: 2020-06-02 DOI: 10.5152/eurasianjmed.2019.19107

Omer Araz, Adem Karaman, Elif Yilmazel Ucar, Leyla Saglam, Metin Akgun

引用次数: 0

Evaluation of Necrotic, Edematous and Inflammatory Changes in Bone Marrow and Soft Tissue After Irrigation with Different Concentrations of NaOCl Solution: An Experimental Study in Rat Tibia. 不同浓度NaOCl溶液灌洗对大鼠胫骨骨髓和软组织坏死、水肿和炎症变化的影响。

IF 1.5

The Eurasian Journal of Medicine Pub Date : 2020-10-01 Epub Date: 2020-06-09 DOI: 10.5152/eurasianjmed.2020.19216

Kursad Aytekin, Aslihan Duman, Feyza Yildiz Aytekin, Ilkay Cinar, Esra Akdeniz, Selcuk Takir, Cem Zeki Esenyel

{"title":"Evaluation of Necrotic, Edematous and Inflammatory Changes in Bone Marrow and Soft Tissue After Irrigation with Different Concentrations of NaOCl Solution: An Experimental Study in Rat Tibia.","authors":"Kursad Aytekin, Aslihan Duman, Feyza Yildiz Aytekin, Ilkay Cinar, Esra Akdeniz, Selcuk Takir, Cem Zeki Esenyel","doi":"10.5152/eurasianjmed.2020.19216","DOIUrl":"https://doi.org/10.5152/eurasianjmed.2020.19216","url":null,"abstract":"Objective: We aimed to investigate effects of different concentrations (0.5-5%) of Sodium Hypochlorite (NaOCl) solution on healthy tissues, and determine the optimal concentration that does not harm to tissue.Materials and methods: 30 tibias of 15 male Wistar albino rats were used. The tibias were randomly divided into 5 groups (Salin, 0.5%, 1%, 2.5%, and 5% NaOCl). Tibias were reamed intramedullary, and irrigated with 20 ml of saline or increasing concentrations of (0.5-5%) NaOCl. The tibias were embedded in paraffin and the sections were stained with hematoxylin-eosin. All sections were assessed for edema, acute inflammation, or necrosis according to their density, in bone marrow and soft tissues.Results: Pairwise comparisons revealed that irrigation of tibia with saline or 0.5% NaOCl solutions was not statistically significant in terms of necrosis in the bone marrows (p=0.320). However, irrigation of rat tibia with saline caused less necrosis in the bone marrows compared to high concentrations (1%, 2.5%, and 5%) of NaOCl (saline and 1% NaOCl, p=0.017; saline and 2.5% NaOCl, p=0.0007; saline and 5% NaOCl, p=0.001).Conclusion: As an irrigation solution, the effects of 0.5% NaOCl are similar to those of saline in terms of edema, inflammation, and necrosis. There is a need for evaluation of necrosis for extended periods such as one week or one month by immunohistochemical methods and flow cytometry.","PeriodicalId":517142,"journal":{"name":"The Eurasian Journal of Medicine","volume":"52 3","pages":"243-248"},"PeriodicalIF":1.5,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651761/pdf/eajm-52-3-243.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38618063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0