Journal of the Korean Association of Oral and Maxillofacial Surgeons最新文献

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Application of navigation system during surgery for medication-related osteonecrosis of the jaw. 导航系统在颌骨药物相关性骨坏死手术中的应用。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.174
Yuri Takeda, Yuka Iwamae, Shizu Saito, Yushi Ezoe, Shinnosuke Nogami, Kensuke Yamauchi
{"title":"Application of navigation system during surgery for medication-related osteonecrosis of the jaw.","authors":"Yuri Takeda, Yuka Iwamae, Shizu Saito, Yushi Ezoe, Shinnosuke Nogami, Kensuke Yamauchi","doi":"10.5125/jkaoms.2025.51.3.174","DOIUrl":"10.5125/jkaoms.2025.51.3.174","url":null,"abstract":"<p><p>In recent years, surgical navigation systems have shown remarkable development and allow real-time navigation of the surgical field, including locations of anatomical structures and lesions. This ability allows procedures to be performed with a high degree of accuracy. In cases of medication-related osteonecrosis of the jaw (MRONJ), proper removal of sequestrum or necrotic bone is essential for postoperative healing. However, the boundary between necrotic and healthy bone is difficult to determine in preoperative images, and there are no clear standards regarding the extent of bone resection for MRONJ. Reported here are findings associated with surgical navigation for MRONJ to determine the extent of bone resection in real time. The technique is reliable for removal of necrotic bone and provides a better understanding of the extent of resection required.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"174-179"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival rate of dental implants in the anterior mandible: a retrospective study. 前下颌骨种植体成活率的回顾性研究。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.141
Su-Yeon Kim, Yu-Lee Kim, Hyun-Jun Kong
{"title":"Survival rate of dental implants in the anterior mandible: a retrospective study.","authors":"Su-Yeon Kim, Yu-Lee Kim, Hyun-Jun Kong","doi":"10.5125/jkaoms.2025.51.3.141","DOIUrl":"10.5125/jkaoms.2025.51.3.141","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to analyze the survival rate of implants placed in the anterior mandible to evaluate the impact of various prosthetic restoration parameters, including loading protocols, opposing teeth type, prosthesis type, retention type, and cantilever, on implant survival and to evaluate potential risk factors, including systemic disease, associated with implant failure.</p><p><strong>Patients and methods: </strong>: Here, 604 implants installed in the anterior lower jaws of 326 patients that had at least one follow-up visit after prosthetic restoration were included. Implant failure was defined as removal of the implant from the oral cavity. For survival rate analysis, the survival period was defined from the date of implantation to the date of failure or last examination. Survival analysis was conducted using Kaplan-Meier survival curves. Cox regression analysis was performed to identify factors affecting implant survival.</p><p><strong>Results: </strong>Of the 604 implants placed in the mandibular anterior region, 14 failed, a cumulative survival rate of 97.68%. The survival curve varied according to loading method, with immediate loading demonstrating a significantly lower cumulative survival rate compared to early and conventional loading. Survival curves also differed according to retention type, with screw-retained implants having significantly lower cumulative survival than cement-retained and attachment-retained implants. Cantilevered designs also showed significantly reduced cumulative survival compared to non-cantilevered designs. Conventional loading was significantly less likely to fail compared to immediate loading.</p><p><strong>Conclusion: </strong>The design of implant-supported prostheses affects the survival of implants placed in the mandibular anterior region. Immediate loading is a risk factor associated with failure of implants in the anterior mandible.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"141-150"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of non-medication-related osteonecrosis and medication-related osteonecrosis of the jaw: a pilot study. 颌骨非药物相关性骨坏死与药物相关性骨坏死的比较:一项初步研究。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.151
Ilgin Ari, Ecem Usman, Selen Adiloğlu, Alper Aktaş
{"title":"Comparison of non-medication-related osteonecrosis and medication-related osteonecrosis of the jaw: a pilot study.","authors":"Ilgin Ari, Ecem Usman, Selen Adiloğlu, Alper Aktaş","doi":"10.5125/jkaoms.2025.51.3.151","DOIUrl":"10.5125/jkaoms.2025.51.3.151","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to compare composite radiographic index (CRI-index) findings of medication-related osteonecrosis of jaws (MRONJs) and non-medication related osteonecrosis of jaws (n-MRONJs) and predict factors predictive of recurrence and healing delays.</p><p><strong>Materials and methods: </strong>Patients referred to our clinic for stage 2 and 3 MRONJ and n-MRONJ between 2020 and 2023 were included in this study. Microorganisms were isolated in samples of excised bone obtained from the adjacent bone by surgery. CRI-index was evaluated using radiological data. Patient age, sex, causes and localization of osteomyelitis, as well as intraoperative and postoperative complications were recorded.</p><p><strong>Results: </strong>There were no statistically significant differences in CRI-index score between the two groups (<i>P</i>>0.05). Presence of <i>actinomyces</i> colonies was not a significant predictor of recurrence or healing status. Furthermore, the presence of <i>actinomyces</i> colonies was not predictive of recurrence in the MRONJ group (<i>P</i>=0.035); however, the use of the antiresorptive agent denasumab was found to be a risk factor for recurrence in the MRONJ group (<i>P</i>=0.035).</p><p><strong>Conclusion: </strong>Radiological and clinical findings were similar for MRONJ and n-MRONJ patients. However, although treatment methods for these two groups is almost identical, the follow-up process can vary. <i>Actinomyces</i> presence was not a predictive factor for recurrence of any type of osteonecrosis. To predict recurrence and healing delays, more parameters need to be investigated.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"151-160"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The new face of oral and maxillofacial surgery: artificial intelligence's expanding role. 口腔颌面外科的新面孔:人工智能的扩展作用。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.127
Seong-Gon Kim
{"title":"The new face of oral and maxillofacial surgery: artificial intelligence's expanding role.","authors":"Seong-Gon Kim","doi":"10.5125/jkaoms.2025.51.3.127","DOIUrl":"10.5125/jkaoms.2025.51.3.127","url":null,"abstract":"","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"127-130"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "Predicting risk factors for complications in jaw cyst treatment: insights from a retrospective study". 评论“预测颌骨囊肿治疗并发症的危险因素:来自回顾性研究的见解”。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.187
Manas Bajpai
{"title":"Comment on \"Predicting risk factors for complications in jaw cyst treatment: insights from a retrospective study\".","authors":"Manas Bajpai","doi":"10.5125/jkaoms.2025.51.3.187","DOIUrl":"10.5125/jkaoms.2025.51.3.187","url":null,"abstract":"","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"187"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From resection to reconstruction: patient-specific temporomandibular joint replacement in patients with ameloblastomas - a report of three cases. 从切除到重建:患者特异性颞下颌关节置换术治疗成釉细胞瘤-附3例报告。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.180
Sujeeth Kumar Shetty, Tarangini Saran, Sonakshi Prakash
{"title":"From resection to reconstruction: patient-specific temporomandibular joint replacement in patients with ameloblastomas - a report of three cases.","authors":"Sujeeth Kumar Shetty, Tarangini Saran, Sonakshi Prakash","doi":"10.5125/jkaoms.2025.51.3.180","DOIUrl":"10.5125/jkaoms.2025.51.3.180","url":null,"abstract":"<p><p>Ameloblastomas involving the temporomandibular joint (TMJ) present unique reconstructive challenges. This case series introduces patient-specific TMJ prostheses as an innovative solution for complex mandibular defects, addressing critical limitations in traditional reconstruction methods by eliminating donor site morbidity and optimising functional outcomes. Three patients presented with follicular ameloblastomas in the posterior mandible, experiencing significant tumour involvement affecting mandibular function and facial aesthetics. Clinical findings included extensive tumour growth in the mandible extending towards the condyle and compromising TMJ function. Surgical management involved complete tumour resection followed by immediate reconstruction using custom TMJ replacement (TMJR) prostheses. The prosthetic solution comprised titanium alloy mandibular components with integrated dental implants and ultra-high-molecular-weight polyethylene glenoid fossa components. Virtual surgical planning facilitated precise prosthesis design, enabling complete tumour removal while maintaining facial symmetry and temporomandibular function. Patient-specific TMJR offers a transformative approach to managing complex mandibular defects. Key takeaways include the potential for precise anatomical reconstruction, reduced surgical complications, and simultaneous restoration of function and aesthetics.a.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"180-186"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of non-chronic odontogenic sinusitis: maxillary sinus lavage via extraction socket after tooth or implant removal. 非慢性牙源性鼻窦炎的治疗:拔除牙齿或种植体后通过拔牙槽冲洗上颌窦。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.168
Ji-Yun Kim, Pil-Young Yun, Jeong-Kui Ku
{"title":"Treatment of non-chronic odontogenic sinusitis: maxillary sinus lavage via extraction socket after tooth or implant removal.","authors":"Ji-Yun Kim, Pil-Young Yun, Jeong-Kui Ku","doi":"10.5125/jkaoms.2025.51.3.168","DOIUrl":"10.5125/jkaoms.2025.51.3.168","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluates the feasibility and clinical outcomes of treating acute or subacute odontogenic maxillary sinusitis using sinus irrigation through an extraction socket following the extraction of the causative tooth or implant.</p><p><strong>Materials and methods: </strong>This retrospective case series included patients over 19 years old with acute or subacute odontogenic maxillary sinusitis who underwent maxillary sinus lavage through the extraction socket to resolve non-chronic odontogenic maxillary sinusitis. Exclusion criteria were previous sinus surgery, bilateral disease, or maxillary sinus pathology unrelated to dental origin. The treatment involved extracting the causative tooth or implant, intentionally perforating the sinus through the extraction socket with a 19-gauge needle, and performing sinus irrigation with saline. Antibiotic therapy was administered based on culture and sensitivity results.</p><p><strong>Results: </strong>Seven patients were included. Following the removal of causative teeth or implants, the average number of sinus irrigation sessions via the extraction socket required to resolve symptoms was 2.7±1.3. Saline irrigation combined with appropriate antibiotic treatment led to symptom resolution.</p><p><strong>Conclusion: </strong>Treating non-chronic odontogenic maxillary sinusitis through sinus irrigation via the extraction site, combined with appropriate antibiotic therapy, was effective in resolving symptoms and avoiding additional surgeries.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"168-173"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of close surgical margins on prognosis and recurrence of oral squamous cell carcinoma. 闭合切缘对口腔鳞状细胞癌预后及复发的影响。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.161
Kavitha Prasad, A Nityasri, Jugal Ashok Toprani, Shashank Madhusudan
{"title":"Effects of close surgical margins on prognosis and recurrence of oral squamous cell carcinoma.","authors":"Kavitha Prasad, A Nityasri, Jugal Ashok Toprani, Shashank Madhusudan","doi":"10.5125/jkaoms.2025.51.3.161","DOIUrl":"10.5125/jkaoms.2025.51.3.161","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the relationships of close surgical margins with recurrence and prognosis of oral squamous cell carcinoma (OSCC).</p><p><strong>Materials and methods: </strong>This retrospective study consisted of 198 patients who were diagnosed with OSCC based on histopathology. All patients underwent wide local tumor resection and neck dissection, followed by or preceded by chemotherapy and/or radiotherapy. The tumor variables assessed were the pathological stage of disease, involvement site, tumor size, margin status, tumor differentiation, bone involvement if any, presence of lymphovascular or perineural invasion, adjuvant therapies including chemotherapy and radiotherapy, lymph node involvement, and ratio.</p><p><strong>Results: </strong>The outcome of the disease based on margins was statistically significant, with close mar- gins associated with increased risk of disease fatality. Recurrence was associated with close margins, followed by adequate margins, and the relation-ship was significant within the first 2 years. Tumor stage and size significantly correlated with margin status. Close surgical margins correlated with one positive lymph node.</p><p><strong>Conclusion: </strong>Close surgical margins are strong predictors for determining prognosis of OSCC.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"161-167"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the letter regarding factors contributing to complications following jaw cyst treatment. 回复有关颌骨囊肿治疗后并发症因素的信函。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.188
Yei-Jin Kang, Ji-Hyeon Oh
{"title":"Response to the letter regarding factors contributing to complications following jaw cyst treatment.","authors":"Yei-Jin Kang, Ji-Hyeon Oh","doi":"10.5125/jkaoms.2025.51.3.188","DOIUrl":"10.5125/jkaoms.2025.51.3.188","url":null,"abstract":"","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"188"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A deep and multi-helix flute threaded implant: a review and clinical analysis. 一种多螺旋深槽螺纹种植体:综述及临床分析。
IF 0.9
Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2025-06-30 DOI: 10.5125/jkaoms.2025.51.3.131
Kyeong Jun Lee, Kezia Rachellea Mustakim, Mi Young Eo, Mi Hyun Seo, Soung Min Kim
{"title":"A deep and multi-helix flute threaded implant: a review and clinical analysis.","authors":"Kyeong Jun Lee, Kezia Rachellea Mustakim, Mi Young Eo, Mi Hyun Seo, Soung Min Kim","doi":"10.5125/jkaoms.2025.51.3.131","DOIUrl":"10.5125/jkaoms.2025.51.3.131","url":null,"abstract":"<p><strong>Objectives: </strong>Implant success depends on osseointegration that is influenced by macrogeometry, including thread design. Thread macrogeometry has a crucial role in achieving primary stability, particularly in low-density bone. Our study reviews the thread design's impact on implant stability, focusing on Straumann BLX (Straumann Co.) implants for practical insights.</p><p><strong>Materials and methods: </strong>We searched the PubMed/MEDLINE and Embase for studies released until August 2023 using the following keywords: \"implant\", \"macrogeometry\", \"thread\", \"thread depth\", \"thread pitch\", \"thread geometry\", \"macrodesign\", \"flute\", \"osseointegration\", and \"stability\". In addition, 58 Straumann BLX implants with dynamic threads, which feature a deep thread design and incorporate a multi-helix flute structure to enhance primary stability across different bone densities, were reviewed retrospectively at our institute.</p><p><strong>Results: </strong>The literature demonstrated that thread pitch, depth, and flute design significantly affect stress distribution and initial stability, especially in low-density bone. Implants with deep threads and spiral flutes showed improved primary stability and insertion efficiency. Clinically, retrospective data from 58 cases supported favorable outcomes in challenging bone conditions such as posterior maxilla and implant replacement sites.</p><p><strong>Conclusion: </strong>We need to determine appropriate designs for implants with the consideration of bone quality and implantation bed condition.</p>","PeriodicalId":51711,"journal":{"name":"Journal of the Korean Association of Oral and Maxillofacial Surgeons","volume":"51 3","pages":"131-140"},"PeriodicalIF":0.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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