Substance use & addiction journal最新文献

{"title":"Peer Prescriber Support Strategies to Increase Buprenorphine Prescribing in Primary Care.","authors":"Katherine King, Elizabeth A Abrams, Cheyenne Fenstemaker, Benjamin Obringer, Lindsay Y Dhanani, Vivian Go, William C Miller, Berkeley Franz","doi":"10.1177/29767342251376812","DOIUrl":"10.1177/29767342251376812","url":null,"abstract":"<p><strong>Background: </strong>Opioid use disorder continues to cause significant morbidity and mortality in the United States. Buprenorphine is a highly effective treatment option, but is not easily accessible due in part to an insufficient prescriber workforce. Primary care professionals (PCPs) have the potential to greatly improve access to buprenorphine, but they report significant barriers such as inadequate addiction training. This study aimed to characterize the value of different peer prescriber support training models for PCPs practicing in urban and rural clinics in Ohio.</p><p><strong>Methods: </strong>We interviewed 26 purposively sampled PCPs as part of a clinical trial planning grant to develop and pilot a buprenorphine prescribing support program. PCPs provided feedback on the training module and additional training needs during semi-structured interviews. Interviews were coded using an inductive approach, informed by grounded theory.</p><p><strong>Results: </strong>PCPs expressed a need for support from other buprenorphine prescribers and on-the-job shadowing and consultation opportunities to confidently prescribe buprenorphine. Interactions with colleagues who did not support or prescribe medications for opioid use disorder (MOUD) were similarly influential, reducing PCPs' interest in prescribing buprenorphine. Internal mentorship opportunities, like starting with managing a few stable patients in collaboration with current prescribers, improved PCPs' comfort with MOUD, but were more available in urban than rural clinics. Structured external mentorship, including real-time consultation options, was also beneficial, especially for rural PCPs.</p><p><strong>Conclusion: </strong>Support from buprenorphine prescribers, both peer PCPs and external experts, may be a useful strategy for overcoming reluctance to prescribe buprenorphine in primary care. On-site peer mentors may be more readily available to urban providers. More research is needed to understand effective strategies for fostering rural peer prescriber mentorship networks, especially in the absence of on-site mentors. Future research should test innovative strategies for bolstering rural and urban addiction mentorship networks.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"418-428"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12614336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Acceptability of Restroom Motion Sensors for Detecting Overdoses.","authors":"Ju Nyeong Park, Haley McKee, Susan E Ramsey, Josiah D Rich, Traci C Green, Hannah E Frank, Avik Chatterjee, Joseph G Rosen","doi":"10.1177/29767342251370822","DOIUrl":"10.1177/29767342251370822","url":null,"abstract":"<p><strong>Background: </strong>Most US drug use events that lead to a fatal overdose are unwitnessed. Given the scale of the overdose crisis, interventions to help detect and respond to overdoses in community settings are urgently needed. Overdose detection technologies (ODT), including reverse-motion restroom sensors, are a promising set of interventions that are underutilized. This study explored the perspectives of frontline harm reduction workers, clinicians, housing shelter staff, and their clients on restroom sensors.</p><p><strong>Methods: </strong>Staff and program client focus groups conducted between December 2022 and January 2024 discussed prior experiences of responding to overdoses and existing organizational overdose policies and procedures. A verbal and visual description of restroom sensors was given and supplemented with brief captioned educational videos to assess the feasibility and acceptability of restroom sensor implementation.</p><p><strong>Results: </strong>We conducted N = 8 discussions (n = 40 participants total). Staff described the anxiety and cognitive burden of monitoring client restrooms and the trauma of witnessing and responding to overdoses. Sites varied in their safety procedures, ranging from manual door knocks every 5 minutes to every 24 hours. Participants embraced the prospect of restroom sensor implementation in community drop-in centers, housing programs, and public restrooms (eg, food service). Perceived benefits of restroom sensors, in addition to saving lives, included the low-threshold and automated nature of the technologies and potential reductions in stress, anxiety, and trauma. However, participants shared concerns surrounding data confidentiality, potential legal repercussions of being found onsite after overdosing (eg, loss of housing, job, children, freedom), stigmatizing attitudes among first responders, reactions to ODTs among clients who mistrust technologies, corporations, and the government, staff fatigue, and technology maintenance.</p><p><strong>Conclusion: </strong>Our findings demonstrated high acceptability of ODTs among staff and patients but revealed several programmatic and policy considerations that could support future implementation efforts.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"345-353"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12859746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145180825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation and Comparison of Travel Burden to Outpatient, Opioid Treatment Program, and Residential Substance Use Disorder Treatment Programs.","authors":"Marcus A Bachhuber, Chinazo O Cunningham, Pat Lincourt, Ashly E Jordan","doi":"10.1177/29767342251370825","DOIUrl":"10.1177/29767342251370825","url":null,"abstract":"<p><strong>Background: </strong>Transportation can be a significant access barrier to effective substance use disorder (SUD) treatment and potentially influence treatment decisions. We aimed to estimate and compare the travel time and cost for outpatient (3 visits/week), opioid treatment program (OTP, 3 visits/week), and residential treatment (1 visit).</p><p><strong>Methods: </strong>For a 28-day period, we compared travel time and costs for SUD treatment programs using a cross-sectional geospatial analysis of New York State data (March 2024). We estimated travel times using public transit in New York City (NYC) and driving outside of NYC. We estimated travel costs using public transit fares and the standard mileage rate. For comparisons, we used population-weighted paired <i>t</i>-tests both statewide and within urbanicity categories (NYC, urban non-NYC, and rural).</p><p><strong>Results: </strong>Statewide, OTPs required the longest mean travel times (7.8 hours) and highest mean costs ($139.92), followed by outpatient treatment (4.4 hours, $80.15) and residential treatment (35.9 minutes, $9.28), with a similar pattern in each urbanicity category. In rural areas, compared with residential treatment, the mean travel time for outpatient treatment was longer by 7.44 hours (95% CI: 7.27, 7.61) and more costly by $206.47 (95% CI: 201.03, 211.90) and the mean travel time for OTPs was longer by 13.06 hours (95% CI: 12.75, 13.37) and more costly by $399.67 (95% CI: 388.36, 410.98). Further, in rural areas, compared with outpatient treatment, the mean travel time to OTPs was longer by 5.61 hours (95% CI: 5.32, 5.92) and more costly by $193.21 (95% CI: 181.98, 204.43).</p><p><strong>Conclusions: </strong>Transportation burdens are significantly higher for outpatient treatment and OTPs compared with residential treatment, and for OTPs compared with outpatient treatment, especially in rural areas. Reducing travel time and cost through strategies including telehealth, flexible methadone take-home dosing, mobile medication units, and integration of methadone treatment into other outpatient programs are needed to improve accessibility.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"556-563"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12628824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145454296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing an Algorithm for Temporary Bans on New Psychoactive Substances: A Delphi Consensus Study.","authors":"Min Hyeok Hwang, Jee Woo Park, Hyun Sil Jung, Jeong Min Go, Jae Hoon Cheong, Ha-Lim Jeon","doi":"10.1177/29767342251380375","DOIUrl":"10.1177/29767342251380375","url":null,"abstract":"<p><strong>Background: </strong>To develop a valid algorithm for temporary bans on new psychoactive substances (NPSs) to minimize the intervention of the subjective opinions of experts in the temporary scheduling process.</p><p><strong>Methods: </strong>This study consisted of a preliminary survey, a 2-phase Delphi survey, and a final consensus survey. In Phase 1 of the Delphi survey, the importance of 7 criteria for designating subjects of temporary bans, as confirmed through a preliminary survey, was evaluated. Phase 2 survey was conducted to investigate the suitability of detailed questions representing the key criteria to be included in the algorithm. In the final phase, the final algorithm was selected, and several questions regarding the expert evaluation of the algorithm were asked. The mean scores of importance and the content validity ratio were calculated for consistency.</p><p><strong>Results: </strong>Nineteen panelists participated in a Delphi survey. The experts agreed on 5 criteria and 22 detailed questions for designating subjects of temporary bans. The finally selected algorithm involves primary evaluation of 'Abuse potential and dependence', 'Social risks', and 'Regulatory cases in reference countries' and secondary considerations about 'Pharmacological effects on the central nervous system' and 'Toxicity and harmfulness'. For expert evaluation, the preferred number of participating experts was 7. Many participants (77.8%) responded that the average expert evaluation score for temporary bans was 2 or higher.</p><p><strong>Conclusions: </strong>We developed a valid algorithm for temporary bans on NPS that can effectively regulate NPS and prevent the spread of addictive substances.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"454-463"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145454258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive Symptoms and Smoking Cessation Success at 12-Month Follow-Up After a Smoking Cessation Treatment: The Moderating Role of Past Quit Attempts.","authors":"María Ramos-Carro, Carmela Martínez-Vispo, Ana López-Durán, Elisardo Becoña","doi":"10.1177/29767342251370820","DOIUrl":"10.1177/29767342251370820","url":null,"abstract":"<p><strong>Background: </strong>Previous research indicated that having made previous quit attempts increased the likelihood of achieving smoking cessation, and that people with depressive symptoms have more difficulties in quitting smoking. However, how previous quit attempts may affect the relationship between depressive symptoms and long-term smoking cessation has not been studied. This study aims to investigate the interactive effect of previous quit attempts in the relationship between depressive symptoms and cessation at the 12-month follow-up after a psychological intervention for smoking cessation.</p><p><strong>Methods: </strong>The sample comprised 509 participants who smoked (<i>M</i>_age = 45.35, 61.7% female) requesting treatment to quit smoking. Depressive symptoms were assessed at baseline using the Beck Depression Inventory-II. Participants who did not smoke in the previous 30 days were considered to have quit smoking at the 12-month follow-up.</p><p><strong>Results: </strong>Regression analyses showed a significant interaction between depressive symptoms and previous quit attempts. Concretely, those participants with higher depressive symptoms and no previous quit experiences were less likely to report quitting at 12-month follow-up compared to those who reported two or more previous quit attempts (OR = 0.45, <i>P</i> = .016). These findings were confirmed by stratified regression models, which showed that depressive symptoms were significantly negatively associated with cessation only among those participants without previous quit attempts (OR = 0.43, <i>P</i> = .004).</p><p><strong>Conclusion: </strong>Findings of the present study suggest that not having previous experience in quitting smoking may impact the relationship between depressive symptoms and long-term cessation in seeking-treatment people who smoke. These findings could be used in clinical practice to improve long-term smoking cessation success.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"337-344"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives From Alcohol and Drug Clinicians Towards the Introduction of Peer Worker Roles Within an Australian Alcohol and Other Drug Treatment Service.","authors":"John Kelly, Emma Armitage","doi":"10.1177/29767342251370470","DOIUrl":"10.1177/29767342251370470","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to investigate the views and perspectives of alcohol and drug (AOD) clinicians regarding the introduction of a peer worker (PW) role within an Australian AOD treatment service, to identify strengths and barriers to guide the integration.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted with AOD clinicians, using a brief, anonymous survey, to gather quantitative and qualitative insights into their perceptions of the strengths and barriers of introduction of a PW role within the service.</p><p><strong>Results: </strong>A total of 53 clinicians participated. Results indicated that 62% of clinicians believe that a PW would improve services delivered. Thematic analysis identified 3 main perceived strengths: (i) enhancing engagement and role modeling recovery; (ii) advocacy; and (iii) supporting teams and service culture. Four themes emerged as barriers/concerns: (i) role clarity and scope; (ii) organizational culture; (iii) boundaries; and (iv) PW well-being. Some differences were noted according to clinician's having prior experience working with PW.</p><p><strong>Conclusion: </strong>Few studies have explored the perspectives of AOD clinicians regarding introducing PW roles in an AOD treatment setting. This study highlights that although a majority of AOD clinicians have positive attitudes, many have concerns regarding PW roles, role boundaries, and the legitimacy of peer expertise. Furthermore, organizational readiness, PW well-being, and the integration of PW and lived experience in recovery orientated care within the workplace were areas of concern. Addressing these within staff education and service planning, with organizational leadership, may help to support implementation.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"374-383"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of Difficult Venous Access Among People Who Inject Drugs Utilizing Medical Services in an Urban Hospital Setting.","authors":"Alex Rains, Susan Regan, Sarah Wakeman, Dinah Applewhite","doi":"10.1177/29767342251389739","DOIUrl":"10.1177/29767342251389739","url":null,"abstract":"<p><strong>Background: </strong>Injection drug use (IDU) is associated with health risks, including infections, vascular damage, and overdose. Among those who inject drugs, having trouble accessing veins may lead to riskier injection practices and result in higher morbidity and mortality. This study explores patient characteristics associated with difficult venous access, with particular attention to disparities facing women who use drugs.</p><p><strong>Methods: </strong>Survey data were collected from 120 people who inject drugs who accessed medical services at an urban academic medical center.</p><p><strong>Results: </strong>Most participants were men (68%) in their thirties (56%), of white race (95%), and had experienced housing insecurity in the last 3 months (77%). Heroin and fentanyl were the most commonly injected drugs (79%). Most participants (77%) reported difficulty with venous access. Those with difficult venous access reported a greater number of years of injection experience (median: 15 vs 11, <i>P</i> = .020). Difficult venous access was significantly associated with female gender identity (92% vs 70%, <i>P</i> = .009), injection by someone else (93% vs 64%, <i>P</i> < .001), injection into subcutaneous tissue (95% vs 56%, <i>P</i> < .001), and injection into the neck (96% vs 73%, <i>P</i> = .024).</p><p><strong>Conclusions: </strong>Given that difficult venous access is associated with injection behaviors that portend higher risks of health complications, clinicians and harm reduction providers should discuss venous access with their patients who use drugs and provide counseling around safer injection practices. Future interventions should be tailored to those groups at the highest risk of difficult venous access, including women who use drugs, those who are injected by others, and people with a long history of IDU.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"570-575"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Readiness of Health Professions Students to Work With Patients Who Use Drugs: Construct Validity of the REDUCE-HARM Addiction Curricula Survey Tool.","authors":"Dana A Button, Patrick C M Brown, Hannah R Tierney, Danika Bethune, Ciaran Murphy, Sophia Gámez, Rebecca A Harrison, Ximena A Levander","doi":"10.1177/29767342251380979","DOIUrl":"10.1177/29767342251380979","url":null,"abstract":"<p><strong>Background: </strong>The REadiness to Discuss Use, Common Effects, and HArm Reduction Measure (REDUCE-HARM) is a new survey instrument with 2 subscales intended to assess attitudes toward substance use and confidence in core addiction topics among health professions students. Previously, we validated its content via a modified Delphi process with interdisciplinary experts across the United States. This study assessed the construct validity and reliability of REDUCE-HARM among students in health professions to be used in developing and evaluating addiction-related curricula.</p><p><strong>Methods: </strong>We sent the REDUCE-HARM to early-training nursing, nurse practitioner, pharmacy, and medical students using class-wide email distribution lists at 7 academic medical centers in the United States from December 2021 to October 2022. We evaluated construct validity and reliability for the complete REDUCE-HARM instrument and the attitudes and confidence subscales using psychometric testing. We used <i>t</i>-tests to compare scores between those with and without prior addiction-related experience.</p><p><strong>Results: </strong>Of the 288 participants, 26% were nurses, 9.7% were nurse practitioners, 30.2% were pharmacists, and 34.0% were medical; 52.8% had prior addiction-related experiences. Principal component analysis and confirmatory factor analysis demonstrated a 2-factor structure of the REDUCE-HARM that corresponded with the subscale constructs of attitudes and confidence. Cronbach's alphas were .912 (95% confidence interval [CI] .896-.925), .798 (95% CI .765-.827), and .938 (95% CI .925-.947) for the complete REDUCE-HARM, attitudes subscale, and confidence subscale, respectively. There were significantly higher mean attitude scores (59.8 vs 57.8; scale: 12-72; <i>P</i> = .021) and mean confidence scores (46.8 vs 37.3; scale: 12-72; <i>P</i> < .001) for students with prior addiction-related experiences compared to students without.</p><p><strong>Conclusions: </strong>Our analysis supports the construct validity and reliability of the REDUCE-HARM among early trainee U.S.-based health professions students and the benefit of direct addiction-related experiences. Future research should evaluate responsiveness to addiction-related educational programs and with additional trainee populations.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"429-440"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145590751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Reported and Biologic Assessments of Prenatal Cannabis Use: Ancillary Analysis of a Prospective Observational Cohort.","authors":"Paulina M Devlin, Amanda A Allshouse, Gwen McMillin, Judith H Chung, William A Grobman, David M Haas, Jessica L Pippen, Samuel Parry, Uma M Reddy, George R Saade, Hyagriv N Simhan, Robert M Silver, Torri D Metz","doi":"10.1177/29767342251389751","DOIUrl":"10.1177/29767342251389751","url":null,"abstract":"<p><strong>Background: </strong>We evaluated agreement between self-reports of prenatal cannabis use and biologic assays, and identified factors associated with discordance.</p><p><strong>Methods: </strong>Ancillary analysis of the \"Nulliparous Pregnancy Outcomes Study: Monitoring Mothers to Be\" (nuMoM2b) study, a United States multicenter prospective cohort of pregnant individuals from October 2010 to September 2013. Past 30-day self-reported prenatal cannabis use was assessed at nuMoM2b study visit 2 (16 weeks and 0 days-21 weeks and 6 days), visit 3 (22 weeks and 0 days-29 weeks and 6 days), and at delivery. Biologic detection of cannabis metabolite (11-nor-9-carboxy-delta-9-tetrahydrocannabinol) was performed with urine samples from visit 2 and visit 3 and the umbilical cord at delivery. The agreement between self-report and biologic assay was evaluated with a Kappa statistic. Factors associated with discordance were evaluated with multivariable logistic regression.</p><p><strong>Findings: </strong>Nine thousand one hundred sixteen participants were included, and 434 (4.76%) used cannabis by either self-report or biologic assay. Among participants who used cannabis, 74.5% of prenatal cannabis use at visit 2 and 79.6% of prenatal cannabis use at visit 3 was detected via urine assay and not self-report. Eighty-nine point seven percent of prenatal cannabis at delivery use was detected via cord assay and not self-report. The agreement between self-report and biospecimen assay was fair at visit 2 (Kappa 0.30, 95% confidence interval [CI] 0.24-0.36), fair at visit 3 (Kappa 0.23, 95% CI 0.17-0.29), and slight at delivery (Kappa 0.11, 95% CI 0.01-0.21). Age <30 years, being unmarried, government insurance, and moderate or high perceived stress were associated with discordance between self-reported use and biologic assay.</p><p><strong>Conclusions: </strong>Nearly threefold more prenatal cannabis use was detected by biologic assay compared with self-report. The agreement was fair between self-report and urine assay during pregnancy and slight between self-report and umbilical cord assay at delivery. Several sociodemographic factors were associated with discordance between self-reported use and biologic assay results.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"576-582"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Past-Year Use of Poppers Among New York City Nightclub Attendees, 2017-2024.","authors":"Nina Abukahok, Joseph J Palamar","doi":"10.1177/29767342251372314","DOIUrl":"10.1177/29767342251372314","url":null,"abstract":"<p><strong>Background: </strong>Alkyl nitrites, commonly known as \"poppers,\" have been widely used as recreational inhalants since the 1970s, particularly among men who have sex with men (MSM). Despite regulatory restrictions in the United States, poppers remain available under misleading product labels (eg, nail polish removers). Limited epidemiologic research has focused on trends in prevalence and correlates of poppers use, particularly among populations that include non-MSM individuals.</p><p><strong>Methods: </strong>We analyzed data from a repeated cross-sectional survey of adults entering electronic dance music events at nightclubs in New York City (NYC) between 2017 and 2024 (N = 3332). We estimated trends in past-year poppers use overall and stratified by demographic and drug use-related factors in the NYC nightclub-attending population, and we also delineated correlates of use.</p><p><strong>Results: </strong>We estimated that past-year poppers use increased from 7.2% in 2017 to 18.1% in 2024 (a 151.4% increase; <i>P</i> < .001). Increases were estimated among both males and females (by 115.7% [<i>P</i> = .0013] and 199.4% [<i>P</i> = .003], respectively). While prevalence remained highest among gay males (46.3% in 2024), notable increases were estimated for heterosexual males (with an increase to 6.3% in 2024) and sexual minority females (increasing to 27.5% in 2024). Compared to heterosexual males, sexual minority males and females had higher prevalence of use, and those who used cocaine, ecstasy/MDMA, and/or ketamine also had higher prevalence of use (<i>P</i>s < .05).</p><p><strong>Conclusion: </strong>While sexual minority males remain at highest risk for poppers use, prevalence is also increasing among traditional lower-risk groups, underscoring the need for expanded public health messaging and harm reduction strategies.</p>","PeriodicalId":516535,"journal":{"name":"Substance use & addiction journal","volume":" ","pages":"409-417"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12893342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}