Monaldi Archives for Chest Disease最新文献

{"title":"An epidemiological assessment of health status among a cohort of tuberculosis survivors: prospective research in a western Indian city.","authors":"Venu Shah, Viral Dave, Vaidehi Gohil, Hardika Khanpara","doi":"10.4081/monaldi.2025.3163","DOIUrl":"10.4081/monaldi.2025.3163","url":null,"abstract":"<p><p>Long-term follow-up of tuberculosis (TB) is important to monitor treatment outcomes, prevent relapse, and improve patient care. The aims of the current study are: i) to assess various epidemiological parameters among TB survivors, like mortality and morbidity, with emphasis on recurrence status during pre-defined long-term follow-up; ii) to assess factors responsible for the recurrence of TB among study participants. A prospective observational study was conducted among cured cases of pulmonary TB registered at the TB unit of Ahmedabad City, India. As per the calculated sample size, 180 study participants were recruited by systematic random sampling from a list of cured TB cases from July to September 2021. Follow-ups of participants were conducted at 6, 12, 18, and 24 months post-recruitment. The status of cured cases was assessed by a pre-validated questionnaire. Factors significantly associated with the likelihood of TB were analyzed using logistic regression. Of the total 180 cured TB cases, 22 (12.2%) developed recurrent TB, and 12 (6.6%) deaths were recorded during the entire follow-up duration of 2 years. Among the cases assessed, 106 (71.6%) were found to be asymptomatic in the context of TB at 2 years post-treatment completion. Around 17 (77.2%) recurrent cases were diagnosed within a year of treatment completion. Factors significantly associated with recurrence were age (p=0.01), body mass index (p=0.02), and socio-economic status (p=0.03) of the study population. Overall recurrence assessed during 2 years of post-treatment follow-up among the cohort of TB survivors was 12.2%. As per the study findings, socio-demographic and nutritional factors play a significant role in the development of recurrent TB, highlighting the importance of targeted interventions.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waist circumference and altered metabolic indices are associated with increased resting pulse rate in middle-aged adults.","authors":"Laith Ashour, Zaid Taimeh, Moaiad Hussein, Zeid Jarrar, Nicola Hanna Madani, Noor Mnaa, Layan Ayesh, Ahmad Odeh, Sama Samer Abu Monshar, Muath Mohammad Dabas, Rawan Almejaibal","doi":"10.4081/monaldi.2025.3205","DOIUrl":"10.4081/monaldi.2025.3205","url":null,"abstract":"<p><p>Metabolic indices significantly impact cardiovascular health. Research on the influence of metabolic indices on resting pulse rate in younger adults is needed. Utilizing the National Longitudinal Study of Adolescent to Adult Health (Add Health) Wave 5 Public-use biological data, we performed a multiple linear regression analysis to determine the predictive factors of resting pulse rate in adults aged 32-42 years. We controlled for sex, anthropometrics, lipid indices, diabetic status, blood pressure, and antihypertensive use. The total number of participants was 1839 (weighted n=1,390,763), the mean age was 38.1 [standard deviation (SD)=2.0] and the mean pulse rate was 75.2 (SD=11.6). Notably, body mass index did not exhibit a statistically significant relationship with resting pulse rate. Conversely, females presented a statistically significant higher pulse rate than males when adjusted for other variables [p<0.001; coefficient = 4.83; 95% confidence interval (CI): 3.54-6.13], as did individuals with increased waist circumference (p=0.023; coefficient = 2.62; 95% CI: 0.39- 4.85). The data indicated a progressive rise in pulse rate correlating with elevated low-density lipoprotein and hemoglobin A1C levels, particularly among those with severe hypercholesterolemia (p=0.048, coefficient = 6.42; 95% CI: 0.12-12.71) and diabetes (p<0.001, coefficient = 7.11; 95% CI: 3.3-10.92). A significant increase was also observed in individuals with hypertension stage 1 and 2 [p<0.001 for both; coefficients = 2.98 (95% CI: 1.45-4.52) and 7.2 (95% CI: 5.28-9.12), respectively]. These findings underscore the necessity of considering metabolic indices in understanding the pathophysiology of elevated pulse rates in adults, thereby enhancing comprehension of cardiovascular tachyarrhythmias in younger adults.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal changes in the 6-minute walk test and the Glittre-activities of daily living test in adults with cystic fibrosis.","authors":"Vera Lucia Barros Abelenda, Cláudia Henrique Da Costa, Mônica De Cássia Firmida, Raphael Freitas Jaber De Oliveira, Rogério Rufino, Agnaldo José Lopes","doi":"10.4081/monaldi.2025.3068","DOIUrl":"https://doi.org/10.4081/monaldi.2025.3068","url":null,"abstract":"<p><p>With the increasing use of highly effective modulator therapy (HEMT) in adults with cystic fibrosis (awCF), it is necessary to determine the evolution of the most dynamic physiological markers of this disease, such as the 6-minute walk test (6MWT) and the Glittre-activities of daily living test (TGlittre). The present study aimed to evaluate the 1-year changes in the 6- minute walking distance (6MWD), TGlittre time, and quality of life (QoL) in awCF before the initiation of HEMT and to determine the impact of habitual physical activity (HPA) and chest physiotherapy (CP). This longitudinal study enrolled 24 awCF who completed the 6MWT and TGlittre. Pulmonary function tests, handgrip strength (HGS), and the Cystic Fibrosis Questionnaire-Revised (CFQ-R) were conducted. Measurements were collected at baseline (T1) and 1 year later (T2). The median body mass index increased between T1 and T2 [19.8 (18-24) vs. 21.4 (19-24) kg/m2, p=0.038]. TGlittre time decreased both in relation to the absolute values [3.10 (2.52-3.39) vs. 2.40 (2.00-3.00) minutes, p=0.001] and in relation to the predicted values [127 (116-150) vs. 108 (102-140) % predicted, p=0.001]. Although there was no increase in 6MWD relative to the predicted values, it increased relative to the absolute values [545 (463-654) vs. 617 (540-658) meters, p=0.041]. In relation to the group that did not engage in HPA, individuals who had HPA showed an increase in HGS between T1 and T2 [7.1 (0-20) vs. 0 (-12-3) kgf, p=0.031]. In relation to the group that did not undergo CP, individuals undergoing CP showed an increase in the 'treatment burden'-CFQ-R between T1 and T2 [16.1 (-3-18) vs. -11.2 (-28-1) points, p=0.049]. In conclusion, awCF performed better on TGlittre than on 6MWT. They experienced an improvement in body composition. HPA was correlated with peripheral muscle strength, as were CP and QoL.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incipient and subclinical tuberculosis: a narrative review.","authors":"Malay Sarkar","doi":"10.4081/monaldi.2025.2982","DOIUrl":"https://doi.org/10.4081/monaldi.2025.2982","url":null,"abstract":"<p><p>Mycobacterium tuberculosis has been known to infect humans for eons. It is an airborne infectious disease transmitted through droplet nuclei of 1 to 5 µm in diameter. Historically, tuberculosis (TB) was considered a distinct condition characterized by TB infection and active TB disease. However, recently, the concept of a dynamic spectrum of infection has emerged, wherein the pathogen is initially eradicated by the innate or adaptive immune system, either in conjunction with or independently of T cell priming. Other categories within this spectrum include TB infection, incipient TB, subclinical TB, and active TB disease. Various host- and pathogen-related factors influence these categories. Furthermore, subclinical TB can facilitate the spread of infection within the community. Due to its asymptomatic nature, there is a risk of delayed diagnosis, and some patients may remain undiagnosed. Individuals with subclinical TB may stay in this stage for an indeterminate period without progressing to active TB disease, and some may even experience regression. Early diagnosis and treatment of TB are essential to meet the 2035 targets outlined in the end-TB strategy. This strategy should also include incipient and subclinical TB. This review will focus on the definition, natural history, burden, trajectory, transmissibility, detection, and management of early-stage TB.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing inhaler technique challenges in cognitively impaired chronic obstructive pulmonary disease patients: the impact of customized training programs.","authors":"Vaishnavi V Gaonkar, Vinay V Shanbhag, Shreya S Kajave, Mahek R Mattikop, Mandati Santhosh Reddy","doi":"10.4081/monaldi.2025.3213","DOIUrl":"https://doi.org/10.4081/monaldi.2025.3213","url":null,"abstract":"<p><p>Individuals with chronic obstructive pulmonary disease (COPD) and cognitive impairment (CI) often face difficulties accurately administering inhalers, which are essential for managing their respiratory condition. Many elderly individuals make major errors that prevent proper medicine administration. Maintaining proper inhaler use skills is critical in controlling COPD. Our goal was to examine and evaluate the inhaler use skills of CI patients with COPD during both the initial evaluation and subsequent appointments. The Respiratory Department of KLEs Dr. Prabhakar Kore Hospital and Medical Research Centre, Nehru Nagar, Belagavi, Karnataka, India, was the site of this prospective interventional study. Based on the Montreal Cognitive Assessment Scale (MoCA), a subset of patients with COPD exhibited mild CI. Patients exhibiting improper inhaler-using skills were detected, corrected, and trained. Inhaler techniques were reassessed immediately and at follow-up visits. The modified Medical Research Council scale score (mMRC), COPD assessment test (CAT) score, St. George Respiratory Questionnaire (SGRQ), and pulmonary function tests were reassessed. A total of 56 COPD and CI patients who had made at least one significant mistake when using an inhaler device were added to the study. The mean age was 66.89±9.85 years. When evaluated with MoCA, the mean score was 17.02±3.91. At baseline, the mean number of mistakes was 1.38±0.93, which decreased to 0.54±0.57 after face-to-face demonstration of correct inhaler techniques. Correlational analysis revealed MoCA scores were negatively associated with the number of mistakes (r=-0.344). At follow-up, CAT score (25±5.61 vs. 18.48±5.24 p=0.001), SGRQ score (53.82±20.59 vs. 37.61±22.17 p=0.001), mMRC score (3.21±0.76 vs. 3.20±0.75 p=0.001), and forced expiratory volume in 1 second/forced vital capacity score (66.86±9.35 vs. 70.08±9.07 p=0.001) had significantly improved in patients demonstrating the correct technique. Pharmacist-led interventions demonstrated improvements in health-associated quality of life and therapeutic outcomes for individuals with COPD and CI. The study highlighted the importance of cognitive evaluation in routine COPD therapy, identifying potential impediments to effective therapy, and offering face-to-face presentations of inhaler techniques. The best inhalers and methods for COPD patients experiencing CI should be further investigated, according to the study.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison among three different follow-up models for obstructive sleep apnea syndrome patients: focus on the physiotherapist's role.","authors":"Carla Simonelli, Michele Vitacca, Beatrice Salvi, Manuela Saleri, Mara Paneroni","doi":"10.4081/monaldi.2023.2673","DOIUrl":"10.4081/monaldi.2023.2673","url":null,"abstract":"<p><p>In obstructive sleep apnea syndrome (OSAS) subjects, different follow-up modalities have been proposed to improve adherence to the continuous positive airway pressure (CPAP) device. This retrospective study compares three different health professional approaches dedicated to caring for OSAS patients in three consecutive follow-up periods of 15 months each. The three different follow-up models are i) physician-oriented follow-up (P-F), ii) physiotherapist-oriented follow-up (PT-F), and iii) tele-titration plus PT-oriented follow-up (TT-PT-F). Health personal visits and actions delivered, patients' adherence, CPAP efficacy, and problems under CPAP use were considered for comparison. Data from 122 OSAS patients with a new prescription of CPAP were analyzed: 39 (32.0%) in the P-F, 38 (31.1%) in the PT-F, and 45 (36.9%) in the TT-PT-F period. We found a reduction over time (from 40.9% in P-F to 8.2% in TT-PT-F, p<0.001) in patients missing the 1-year follow-up visit. The PT-F and TT-PT-F lead to a reduction in physician visits in comparison to P-F (5.2% and 8.9% vs. 100%, p<0.001) with no differences in time to the first follow-up visit, CPAP efficacy, and patients' adherence among the three periods. More device-related problems were found in the PT-F (57.8%), compared with the PF (25.6%) period (p<0.001); the most common troubles were mask problems evaluated in 26.2% of cases. In conclusion, different follow-up models offer similar efficacy and short-term adherence for CPAP, leading to a significant reduction in physician visits under the PT-F with or without tele-titration, with mask problems as the most commonly treated. Further analysis should be useful to define the best cost-efficacy follow-up intervention.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergic bronchopulmonary aspergillosis: radiological and microbiological profile of patients presented in an outpatient pulmonary clinic in a developing country.","authors":"Nousheen Iqbal, Muhammad Irfan, Mustafa Bin Ali Zubairi, Maaha Ayub, Safia Awan, Kausar Jabeen, Ali Bin Sarwar Zubairi","doi":"10.4081/monaldi.2023.2803","DOIUrl":"10.4081/monaldi.2023.2803","url":null,"abstract":"<p><p>There is limited data available about allergic bronchopulmonary aspergillosis (ABPA) in Pakistan. The aim of the study was to describe the radiological and microbiological profile of ABPA patients presenting to the outpatient pulmonary clinic of a tertiary care hospital in Karachi, Pakistan. A retrospective study was conducted on ABPA patients who presented to the pulmonary outpatient clinic at Aga Khan University Hospital, Karachi, Pakistan, from January 2017 to December 2019. Data was collected on microbiology and radiology features on a predesigned proforma. A total of 7759 asthmatic patients presented at the outpatient pulmonology clinic during the study period. Of the 245 patients labeled as ABPA, 167 fulfilled the inclusion criteria, and 91 (54.5%) were female (mean age 41.9±13.0 years). A high-resolution computed tomography scan of the chest was available for 126 patients. Of these, 104 (82.5%) patients had bronchiectasis. Central bronchiectasis was noted in 98 (94.2%) patients, mucus plugging in 71 (56.3%), and hyperinflation was seen in 30 (23.4%). Microbiological testing was available in 103/167 (61.7%) patients. The most common bacterial pathogen was Pseudomonas aeruginosa 32 (31.1%), followed by Hemophilus influenzae 16 (15.5%), and Moraxella catarrhalis 7 (9.7%). Aspergillus fumigatus 17 (23.6%) was the most common mold, followed by Aspergillus flavus 16 (22.2%) and Aspergillus niger 11 (15.3%). Co-infection (bacterial and fungal) was found in 18 (17.45%) patients. Bronchiectasis was frequently observed in our cohort of patients with ABPA. P. aeruginosa was found to be common among bacterial pathogens. Isolation of fungus is not uncommon in these patients.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QT interval prolongation in Takotsubo syndrome: a frightening feature with no major prognostic impact.","authors":"Ana Isabel Pinho, Cátia Oliveira, Luís Daniel Santos, Catarina Marques, André Cabrita, Paula Dias, Gonçalo Pestana, Carla Sousa, Rui André Rodrigues","doi":"10.4081/monaldi.2023.2834","DOIUrl":"10.4081/monaldi.2023.2834","url":null,"abstract":"<p><p>Despite the frequent and often severe repolarization abnormalities seen in Takotsubo syndrome (TTS), the underlying mechanism of life-threatening arrhythmias is incompletely understood, and the risk remains uncertain. TTS is considered a potential cause of acquired long QT syndrome; however, there is no robust evidence that QT prolongation has a major prognostic impact on these patients' outcomes. Our aim was to assess the prevalence and clinical implications of acquired long QT during TTS events and compare in-hospital and long-term outcomes between patients with and without corrected QT interval (QTc) prolongation. This is a retrospective cohort study that included 113 patients admitted to our tertiary care hospital with a diagnosis of TTS. The cohort was divided into two groups: a long QTc group (QTc≥460 milliseconds in any electrocardiogram at admission or during hospitalization) and a normal QTc group. Baseline characteristics, occurrences during hospitalization, and outcome data were obtained from the revision of medical registries and hospital visits. Of the 113 patients, 107 (94.7%) were female. The mean age was 67.6±11.7 years. QTc prolongation was found in 38%. Demographic characteristics, relevant chronic medication, prevalence of cardiovascular risk factors, and other comorbidities were similar between the groups, except for a history of atrial fibrillation, which was more common in the long QTc group. Syncope was more prevalent in the long QTc group. In-hospital complications were not statistically different between patients with long and normal QTc (48.8% vs. 44.2%, p=0.637), including ventricular arrhythmias and complete atrioventricular block (both 4.7% vs. 1.4%, p=0.556). In-hospital mortality was 0.9%, corresponding to one patient in the long QTc group. The mean follow-up time was 4.8±3.8 years. 5-year all-cause mortality and the occurrence of the composite endpoint of major adverse cardiac and cerebrovascular events did not differ between the groups (p=0.511 and p=0.538, respectively). Our study found no association between prolonged QTc interval during TTS events and adverse prognosis since in-hospital and long-term outcomes were similar between the groups. Our findings suggest that, although QT prolongation is usually a frightening feature on ECG, this repolarization abnormality during the acute phase has no major prognostic implications in the TTS population.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The ability of the Rehabilitation Complexity Scale to capture the burden of care and disability in patients with respiratory diseases admitted for in-hospital rehabilitation: a pilot study.","authors":"The Rehabilitation Complexity Scale For Respiratory Patients- Italian Network","doi":"10.4081/monaldi.2023.2732","DOIUrl":"10.4081/monaldi.2023.2732","url":null,"abstract":"&lt;p&gt;&lt;p&gt;The aim of this pilot retrospective study was to test the Rehabilitation Complexity Scale (RCS-E v13) in patients from 15 Italian pulmonary rehabilitation (PR) units and correlate it to the most used clinical and functional outcome measures. At admission and discharge, clinical data [comorbidities with the Cumulative Illness Rating Scale, Barthel Index (BI), Barthel Index Dyspnea (BI-d), Chronic Obstructive Pulmonary Disease (COPD) Assessment Test (CAT), and 6-minute walking test (6MWT)] were collected, and RCS-E v13 total score was calculated. A total of 219 patients [30.6% COPD, 43.4% chronic respiratory failure (CRF), and 26% with invasive ventilation (IV)], aged 69.9 (11.2) years, were considered. RCS-E v13 at admission [8.63 (1.69), 11.06 (2.50), 16.56 (2.97)], and at discharge [0.84 (1.02), 2.19 (1.5), 7.09 (1.47)] for COPD, CRF, and IV, respectively, were statistically differed among groups (analysis of variance p≤0.0001). RCS-E v13 total score strongly negatively correlated with 6MWT [rho = -0.7305 (-07883; -0.6598)] and BI [rho = -0.6989 ( -0.7626; -0.6217)], while it correlated weakly with CAT [rho = 0.2939 (0.1601; 0.4170)] and BI-d [rho = 0.3512 (0.2243; 0.4663)]. Change in RCS-E v13 total score [mean change of -8.70; 95% confidence interval (CI) -9.00; -8.40)] as in all single RCS-E v13 items [care -0.59 (95% CI -0.69, -0.48); risk -0.56 (95% CI -0.78;-0.46); nursing needs -2.11 (95% CI -2.22;-2.01); medical needs -2.29 (95% CI -2.39;-2.18); therapy disciplines -1.45 (95% CI -1.57; -1.33); therapy intensity -2.00 (95% CI -2.07; -1,93); equipment -0.23(95% CI -0.30; -0.16)] was found significant after PR. The RCS-E v13 application for patients with respiratory diseases is feasible and highlights a huge difference among different conditions. Its application seems to present an important care burden and relation with motor disability and effort tolerance but a lower relation with dyspnea during activities of daily living, comorbidities, and disease impact. A more robust sample and prospective analysis on the usefulness of the RSC-E v13 in patients with respiratory diseases during rehabilitation are welcomed. ************************************************************ List of authors 1. Michele Vitacca, MD, FERS ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane, Brescia, Italy 2. Luca Bianchi, MD Fondazione Don Carlo Gnocchi ONLUS, \"Centro Spalenza\", Respiratory Rehabilitation, Rovato, Brescia, Italy 3. Piero Ceriana, MD ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Pavia, Italy 4. Francesco Gigliotti, MD Fondazione Don Carlo Gnocchi ONLUS, IRCCS \"Don Carlo Gnocchi\", Respiratory Rehabilitation, Firenze, Italy 5. Rodolfo Murgia, MD ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Montescano, Pavia, Italy 6. Alessia Fumagalli, MD Istituto nazionale Riposo e Cura per Anziani di Casatenovo, Respiratory Rehabilitation, Casatenovo, Lecco, Italy 7. Antonio Spanevello, MD ICS ","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138447020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smoking cessation and its significant role in the Indian scenario.","authors":"Raj Kumar, Manoj Kumar, Sukriti Raj, Dileep Kumar Arisham, Anil Kumar Mavi, Kamal Singh","doi":"10.4081/monaldi.2023.2814","DOIUrl":"10.4081/monaldi.2023.2814","url":null,"abstract":"<p><p>Given the increased health dangers of tobacco use, particularly in developing countries, smoking cessation intervention is crucially important. The aim of this study is to determine and assess the effectiveness of a comprehensive smoking cessation intervention program, incorporating behavior modification, counseling, and pharmacologic treatments, in the Indian scenario. The process of initiating smoking or tobacco cessation begins with the evaluation of the distinct stages that smokers undergo as part of their journey toward behavioral change. There are five different levels of preparation for quitting smoking, i.e., i) not prepared (pre-contemplation); ii) unsure (contemplation); iii) prepared (preparation); iv) action; and v) maintenance. Behavior modification and counseling are essential. The \"5 A's\"-based intervention uses ask, advise, assess, assist, and arrange as part of its strategy. First-line treatments such as nicotine replacement therapy, bupropion, and varenicline, as well as second-line treatments such as clonidine, cytisine, and nortriptyline, are the foundation of pharmacologic care. Every healthcare professional has a duty to help smokers stop using tobacco, and the intervention should be both therapeutic and diagnostic. Combining behavioral and social support yields the best results, along with pharmacotherapy whenever needed.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138483415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}