接受治疗的哮喘患者呼气一氧化氮分数、哮喘控制试验和肺活量测定之间的关系

IF 0.8 Q4 RESPIRATORY SYSTEM
Arthana Kanagaraj, Santhiya Ramachandran, Pajanivel Ranganadin, Akila Mohan
{"title":"接受治疗的哮喘患者呼气一氧化氮分数、哮喘控制试验和肺活量测定之间的关系","authors":"Arthana Kanagaraj, Santhiya Ramachandran, Pajanivel Ranganadin, Akila Mohan","doi":"10.4081/monaldi.2025.3300","DOIUrl":null,"url":null,"abstract":"<p><p>To evaluate the relationship between fractional exhaled nitric oxide (FeNO), asthma control test (ACT), and spirometry measurements in individuals with asthma receiving treatment, a cross-sectional study was conducted involving 47 diagnosed asthmatic patients. FeNO levels were measured using Eversens Evernoa FeNO, ACT scores were recorded, and spirometry (pre- and post-bronchodilator) was conducted. Correlations between these parameters were analyzed using Pearson's correlation and t-tests. The study found no statistically significant correlation between FeNO and spirometry parameters [forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC] or ACT scores. While FeNO was higher in individuals without a family history of asthma and nonsmokers, these differences were not statistically significant. Additionally, spirometry parameters showed significant improvement after bronchodilator use, but FeNO did not strongly predict lung function improvement. The findings suggest that while FeNO is useful as an indicator of airway inflammation, it may not consistently correlate with functional lung measurements or asthma control as assessed by spirometry and ACT. This highlights the need for a multidimensional approach to asthma management that combines these tools for more comprehensive disease assessment.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relationship between fractional exhaled nitric oxide, asthma control test, and spirometry measurement in individuals with asthma receiving treatment.\",\"authors\":\"Arthana Kanagaraj, Santhiya Ramachandran, Pajanivel Ranganadin, Akila Mohan\",\"doi\":\"10.4081/monaldi.2025.3300\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>To evaluate the relationship between fractional exhaled nitric oxide (FeNO), asthma control test (ACT), and spirometry measurements in individuals with asthma receiving treatment, a cross-sectional study was conducted involving 47 diagnosed asthmatic patients. FeNO levels were measured using Eversens Evernoa FeNO, ACT scores were recorded, and spirometry (pre- and post-bronchodilator) was conducted. Correlations between these parameters were analyzed using Pearson's correlation and t-tests. The study found no statistically significant correlation between FeNO and spirometry parameters [forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC] or ACT scores. While FeNO was higher in individuals without a family history of asthma and nonsmokers, these differences were not statistically significant. Additionally, spirometry parameters showed significant improvement after bronchodilator use, but FeNO did not strongly predict lung function improvement. The findings suggest that while FeNO is useful as an indicator of airway inflammation, it may not consistently correlate with functional lung measurements or asthma control as assessed by spirometry and ACT. This highlights the need for a multidimensional approach to asthma management that combines these tools for more comprehensive disease assessment.</p>\",\"PeriodicalId\":51593,\"journal\":{\"name\":\"Monaldi Archives for Chest Disease\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-07-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Monaldi Archives for Chest Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4081/monaldi.2025.3300\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monaldi Archives for Chest Disease","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/monaldi.2025.3300","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0

摘要

为了评估接受治疗的哮喘患者呼气一氧化氮分数(FeNO)、哮喘控制试验(ACT)和肺活量测定之间的关系,对47名确诊的哮喘患者进行了横断面研究。使用Eversens Evernoa FeNO测量FeNO水平,记录ACT评分,并进行肺活量测定(支气管扩张剂使用前和使用后)。使用Pearson相关检验和t检验分析这些参数之间的相关性。研究发现,FeNO与肺活量测定参数[用力肺活量(FVC)、1秒用力呼气量(FEV1)和FEV1/FVC]或ACT评分之间无统计学意义的相关性。虽然FeNO在没有哮喘家族史和不吸烟的个体中较高,但这些差异没有统计学意义。此外,使用支气管扩张剂后,肺功能参数有显著改善,但FeNO不能强烈预测肺功能改善。研究结果表明,虽然FeNO作为气道炎症的一项指标是有用的,但它可能与肺功能测量或哮喘控制不一致,如肺活量测定和ACT评估。这突出了需要一种多维方法来管理哮喘,将这些工具结合起来进行更全面的疾病评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between fractional exhaled nitric oxide, asthma control test, and spirometry measurement in individuals with asthma receiving treatment.

To evaluate the relationship between fractional exhaled nitric oxide (FeNO), asthma control test (ACT), and spirometry measurements in individuals with asthma receiving treatment, a cross-sectional study was conducted involving 47 diagnosed asthmatic patients. FeNO levels were measured using Eversens Evernoa FeNO, ACT scores were recorded, and spirometry (pre- and post-bronchodilator) was conducted. Correlations between these parameters were analyzed using Pearson's correlation and t-tests. The study found no statistically significant correlation between FeNO and spirometry parameters [forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC] or ACT scores. While FeNO was higher in individuals without a family history of asthma and nonsmokers, these differences were not statistically significant. Additionally, spirometry parameters showed significant improvement after bronchodilator use, but FeNO did not strongly predict lung function improvement. The findings suggest that while FeNO is useful as an indicator of airway inflammation, it may not consistently correlate with functional lung measurements or asthma control as assessed by spirometry and ACT. This highlights the need for a multidimensional approach to asthma management that combines these tools for more comprehensive disease assessment.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
3.60
自引率
0.00%
发文量
1
审稿时长
12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信