S. Jalilolghadr, Manouchehr Taghiloo, E. Parsarad, Mohammad Taherahmadi, H. Taherahmadi
{"title":"Evaluation of sleep-disordered breathing in children and adolescents referred to the sleep ward of Qazvin children's hospital during 2014-2019","authors":"S. Jalilolghadr, Manouchehr Taghiloo, E. Parsarad, Mohammad Taherahmadi, H. Taherahmadi","doi":"10.22038/IJP.2021.58958.4598","DOIUrl":"https://doi.org/10.22038/IJP.2021.58958.4598","url":null,"abstract":"Background: Polysomnography is a gold standard method for examination of information obtained from physiological changes in the body related to sleep. The aim of this study was to diagnose respiratory disorders in children and adolescents with sleep disorders using polysomnography.\u0000Methods: In this cross-sectional retrospective study, the complete data of 112 children and adolescents aged 0-18 years that were referred to the sleep ward of Qazvin children's hospital due to sleep disorders were collected. The results of polysomnography and severity of obstructive sleep apnea (OSA) were determined. SPSS 21 software and frequency table were used to determine the prevalence of the variables.\u0000Results: The most common sleep disorder was restless sleep (68; 60.71%). One hundred and four (92.85%) patients had sleep apnea. Also, 66 (58.92%) patients with severe OSA, 19 (16.96%) patients with moderate OSA, 14 (12.5%) patients with mild OSA and 5 (4.46%) patients with central sleep apnea were observed. Eighty eight (78.57%) children had less than normal sleep efficiency (less than 90%) and 34 (30.35%) had normal and desirable sleep efficiency. Total adenotonsilectomy, medical therapy for OSA and non-invasive ventilation (NIV) were recommended for 46 (41.7%), 27 (24.10%) and 20 (17.85%) patients, respectively.\u0000Conclusion: Respiratory disorders symptoms during sleep were seen in our results, especially in children with a history of adenotonsillectomy. Based on the severity of symptoms, medication was prescribed for children. Referral of children suspected to sleep disorders to a physician by parents is essential for control and treatment of this disease.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44264474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samaneh Norooziasl, Zhila Afshar, N. Ghaemi, R. Vakili, S. Alamdaran, Z. Shaye, Peyman Eshraqhi
{"title":"Prevalence of testicular adrenal rest tumor and factors associated with its development in 6 month to 18 years-old patients with congenital adrenal hyperplasia","authors":"Samaneh Norooziasl, Zhila Afshar, N. Ghaemi, R. Vakili, S. Alamdaran, Z. Shaye, Peyman Eshraqhi","doi":"10.22038/IJP.2021.57453.4511","DOIUrl":"https://doi.org/10.22038/IJP.2021.57453.4511","url":null,"abstract":"Introduction: Congenital adrenal hyperplasia (CAH) is a potentially life-threatening form of primary adrenal insufficiency characterized by cortisol, aldosterone, and epinephrine deficiencies, as well as overproduction of androgen. Infertility is one of the most important complications in male patients with CAH, and testicular adrenal rest tumors (TARTs) are known to be the most important caause of infertility in these patients. In the present study, the prevalence of TART and factors associated with its development were evaluated in patients with CAH.\u0000Methods & Materials: This is a descriptive cross-sectional study evaluating 30 males (6 month -18 years) with the classical 21-hydroxylase deficiency (21-OHD) through testicular ultrasonography. Data including age, bone age, puberty, 21-OHD phenotype (salt wasting (SW) or simple virilizing (SV)) and serum levels of 17- hydroxyprogesterone (17-OHP), androstenedione and adrenocorticotropic hormone (ACTH) were records.\u0000Results: The prevalence of TART was determined 56.7%, which increased with age with higher prevalence in children >12 (52.9%) year old. The mean age in patients with TART was 12.4 ± 4.18 years. No association was found between TART and 21-OHD phenotype, androstenedione, or 17OHP levels, but an association was found between TART and elevated levels of ACTH (p= 0.049), advanced bone age (p= 0.030) and puberty (p= 0.003).\u0000 Conclusion: According to the results, TART is very common and can occur in pre-pubertal and young patients, and the disease control could be a factor associated with its development. Therefore, it is suggested to investigate the TART development early in childhood, mainly in poorly controlled 21-OHD patients.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43101119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The evaluation of Left atrial to aortic root after PDA closure in children","authors":"Alireza Teimouri, N. Noori, Saeideh Yaghoubi","doi":"10.22038/IJP.2021.57769.4530","DOIUrl":"https://doi.org/10.22038/IJP.2021.57769.4530","url":null,"abstract":"Ductus arteriosus(DA) is a vascular structure that makes a link between the proximal descending aorta and main pulmonary artery near the origin of the left pulmonary artery. The present study aimed to assess the changes of LA/Ao after PDA closure in children.\u0000Methods\u0000This cross-sectional study was performed on 635 children with PDA in the Ali Asghar clinic, Zahedan-Iran from 2003 to 2019. The children followed for at least one year after discharge from the hospital after intervention. Analyzed performed by SPSS 20.00 with 0.05 as significant error.\u0000Results\u0000Decreasing growth rates of LA/Ao were 24% and 10% in the first and second 6 months after intervention compared with the baseline values. During the first 6 months after intervention, the percentages of LA/Ao reduction were 23%, 25% and 22% in small, medium and large PDA when these percentages were 7%, 13% and 16% during the second 6 months after intervention respectively. Regarding intervention, the percentages were 25%, 24%, 24% and 24% in PDA that closed by medication, surgery, device occluded and VATS in the first six months after intervention. The percentages were 9%, 10%, 11% and 9% for the second 6 months after intervention. The percentages were 24%, 24% and 21% in those PDA with residuals, no complication and PH in the first six months after intervention. This pattern was 8%, 9% and 16.6% for the second 6 months after intervention. \u0000Conclusion\u0000Concluded that LA/Ao had the highest decrease during the first six months after intervention such that moderate PDA size or those PDA who had medication as intervention or those with residuals complication had the highest percentages of reduction.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47170968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nasrin Jalalimanesh, J. Ghanavi, Maryam Hassanzad, P. Farnia, S. J. Sayedi, A. Velayati
{"title":"Evaluation of miR-301b and miR-302b Expression in Serum of Cystic Fibrosis Patients and Association with Clinical Scoring System","authors":"Nasrin Jalalimanesh, J. Ghanavi, Maryam Hassanzad, P. Farnia, S. J. Sayedi, A. Velayati","doi":"10.22038/IJP.2021.60598.4683","DOIUrl":"https://doi.org/10.22038/IJP.2021.60598.4683","url":null,"abstract":"Background \u0000Cystic fibrosis (CF) is an autosomal recessive disorder caused by a mutation in CF transmembrane conductance regulator gene (CFTR). Clinical manifestations of disease and their severity have considerable variations in patients having similar mutation in CFTR gene. This can be due to different polymorphisms, epigenetic changes and microRNAs (miRNAs) as gene modifiers. Considering the proven roles of miR-301b and miR-302b on infection and inflammation, expression of these miRNAs might change in CF patients.\u0000Materials and Methods: In this study, 30 CF patients (homozygous for ΔF508 mutation) and 30 healthy individuals were participated and their demographic data were recorded. The whole RNA was extracted from serum samples and cDNA was synthesized. Using Real-Time PCR, expression levels of miR-301b and miR-302b were measured between patient and normal groups. Patient classification was carried out based on Shwachman-Kulczycki score, and expression levels of these miRNAs were determined in these classifications. All statistical analyses were performed using IBM SPSS software V21.\u0000Results: Statistical analyses of qRT-PCR results showed a significant increase in serum levels of miR-301b and miR-302b expression (p-Values of 0.02 and 0.03; fold changes of 3.73 and 1.95, respectively) in CF patients compared to healthy controls. A significant increase (p<0.05) in miR-301b expression level was observed in severe, moderate and mild groups, while miR-302b expression level was increased in CF patients of severe and moderate groups according to Shwachman-Kulczycki score.\u0000Conclusion\u0000Expression levels of miR-301b and miR-302b are different based on clinical scoring system. This data suggests that expressions of these two miRNAs are influenced by infection and inflammation of CF patients. Further studies can lead to development of innovative treatment strategies.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68362575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahra Nafei, E. Akbarian, Naeimeh Naserzadeh, F. Ferdosian
{"title":"Comparison of RT-PCR, lung CT scan, and anti-COVID-19 antibody results in hospitalized children with suspected COVID-19, Yazd, Iran","authors":"Zahra Nafei, E. Akbarian, Naeimeh Naserzadeh, F. Ferdosian","doi":"10.22038/IJP.2021.59712.4648","DOIUrl":"https://doi.org/10.22038/IJP.2021.59712.4648","url":null,"abstract":"Background: Mild symptoms of COVID-19 in children may lead to delayed or misdiagnosis. Reverse transcription polymerase chain reaction (RT-PCR) is an approved laboratory method for detecting COVID-19 virus. Given that COVID-19 is considered an emerging disease, its diagnostic methods in children have not yet been well compared. Therefore, this study was designed to compare RT-PCR, lung CT scan, and anti-COVID-19 antibody results in hospitalized children with suspected COVID-19.\u0000Methods: This cross-sectional study was conducted on patients under 18 years suspected COVID-19 admitted to Shahid Sadoughi Hospital in Yazd, Iran, from February 2020 to February 2021. All hospitalized children who have suspected COVID-19 based on their initial clinical symptoms or signs and underwent RT - PCR were included in the study. Demographic data such as age, sex, contact history with COVID-19 patients, clinical manifestations, outcome, comorbidities, and information on other paraclinical procedures by checklist were collected.\u0000Results: In total, 53.3% were male, and 59% were under five years old. The most common symptom was fever (81%), followed by respiratory distress (34.3%) and diarrhea (26.7%), and cough (19%). Additionally, a significant relationship was observed between respiratory symptoms and a positive PCR test (P = 0.020) and positive lung CT findings (P = 0.017). This study failed to find a significant association between PCR, chest CT scan, and anti-COVID-19 antibody results with ICU admission, endotracheal intubation, and death (P>0.05).\u0000Conclusions: Our findings showed a significant association between respiratory symptoms and positive RT- PCR and positive CT findings. But no significant relationship was found between PCR, chest CT scan, and anti-COVID-19 antibodies with ICU admission, endotracheal intubation, and death.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46795332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fereshteh Dastres, M. Ghaljeh, Alia Jalalodini, F. Ghaljaei
{"title":"Title: The Effect of Distance Teaching to Mothers on Primary School Boys’ Sleep Habits Related to Computer Games: A Quasi-experimental Study","authors":"Fereshteh Dastres, M. Ghaljeh, Alia Jalalodini, F. Ghaljaei","doi":"10.22038/IJP.2021.60059.4663","DOIUrl":"https://doi.org/10.22038/IJP.2021.60059.4663","url":null,"abstract":"Background:Computer games have often been considered to have a negative impact on the sleep of children. The aim study was to determine the effect of distance teaching to mothers on sleep habits related to computer games of primary school boys of Zahedan in 2020.\u0000Materials and Methods:The present quasi-experimental study was carried out on primary school boys students. 144 students were randomly selected in two groups of intervention and control.Data collection tools included the Child Sleep Habits and demographic information Questionnaire.If the student was in the intervention group,before the intervention,the researcher held a face-to-face meeting with his mother to complete the questionnaire.Then,created a group for mothers in Telegram and WhatsApp,The intervention was made for 4weeks,the researcher sent a text and avideo three times a week to students’mothers based on the content of education.8weeks after,the Sleep Habits Questionnaire was completed by the mothers.If the student was assigned to the control group,demographic information and Sleep Habits Questionnaire were completed by the mothers to begin the pre-test.No intervention was made for this group.The post-test was completed after 8 weeks by the mothers.Data analysis was performed through IBM SPSS.\u0000Results:The results showed that the mean and standard deviation of the sleep habits score and its dimensions in intervention and control groups had no significant difference(P>0.05)before intervention.However,after intervention,the sleep habits score and its dimensions had significant differences(P<0.05). \u0000Conclusion:maintaining the physical and mental health of students is an important responsibility of pediatric nurses and parents.It is suggested that teaching sleep habits to mothers should be considered.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43072909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sadr, Narges Kaveh, K. Agin, R. Choopani, Shahpar Kaveh, Hanieh Tahermohammadi
{"title":"Herbal treatments for asthma, according to Avicenna","authors":"S. Sadr, Narges Kaveh, K. Agin, R. Choopani, Shahpar Kaveh, Hanieh Tahermohammadi","doi":"10.22038/IJP.2021.58082.4553","DOIUrl":"https://doi.org/10.22038/IJP.2021.58082.4553","url":null,"abstract":"Abstract\u0000Background and objectives: Conventional therapies using herbal medicine to treat asthma are employed by practitioners in Iran. The use of herbal medicine for asthma is rooted in traditional knowledge. Scientific evaluation of these historical documents could be valuable to find new potential applications in conventional medicine. Traditional Persian Medicine (TPM), which is widely known with the manuscripts of Avicenna and Rhazes, is one of the most ancient medical set of beliefs.\u0000Methods: In this study, firstly we introduce a series of medicinal plants that would be enormously valuable for treating asthma on the basis of Avicenna (The Canon of Medicine by Avicenna). After that, we review medicinal plants properties found in the pharmacological studies from electronic databases and then discuss their mechanism of action in asthma. \u0000For a detailed review, relevant abstracts and articles related to the above-mentioned areas were selected, including review articles on the subjects, along with clinical trial studies in animals and humans.\u0000Results: The physicians of ancient Iran such as Avicenna treated asthma patients with a variety of medicinal herbs. Some of these herbs are currently used, while others have the potential to be used in the future of asthma management.\u0000Conclusions: This study demonstrates that the investigated plants are consistent with new studies; therefore, different components of these herbs can be utilized in manufacturing new drugs. Future clinical studies on healthy volunteers and also patients suffering from asthma and reactive airway disease are compulsory to confirm the effectuality of these plants as complementary interventions in asthma.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49185197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdolhamid Jafari Nodoushan, S. J. Sayedi, A. Najarzadeh, M. Karimi, A. Golzar
{"title":"Dietary Intake of Macro- and Micronutrients in children: Comparison with Reference Values","authors":"Abdolhamid Jafari Nodoushan, S. J. Sayedi, A. Najarzadeh, M. Karimi, A. Golzar","doi":"10.22038/IJP.2021.58272.4561","DOIUrl":"https://doi.org/10.22038/IJP.2021.58272.4561","url":null,"abstract":"Background: One of the most important factors in maintaining and improving children's health is the quality of diet.\u0000\u0000Objectives: The aim of this study was to determine the micro and macro nutrient intakes in children aged less than five years old with malnutrition.\u0000\u0000Methods: The cross-sectional study included 75 under-five children referring to primary health care center in Taft. Children classified in two groups by nutritional status according to a variety of anthropometric indicators. Food intake was assessed using 24 hour food recalls and then was compared to the recommended daily amount (RDA). Anthropometric measures of age, height/length and weight and measurements head circumference were obtained and compared with reference anthropometric indices to assess nutritional status\u0000\u0000Results: The subjects consisted of 41 boys and 34 girls who were 36 (48%) in the malnourished group and 39 (52%) in another group. The analysis of food intake indicated that most micronutrients were within recommendations, except for calcium, zinc, iron and folate (P<0. 05). The intake of macronutrients, was above recommendations and energy intake was in the general appropriate level.\u0000\u0000Conclusion: The findings of the study indicated that the appropriate level of macronutrients intake was used and the problem was mainly existed in micronutrients’ consumption. Based on the results we recommended planning for nutrition education program.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48675011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Somayeh Heshmat Alvandi, M. Ghojazadeh, M. Heidarzadeh, S. Dastgiri, Hooman Nateghian
{"title":"Using Bagging Neural Network to Predict the Factors Affecting Neonatal Mortality","authors":"Somayeh Heshmat Alvandi, M. Ghojazadeh, M. Heidarzadeh, S. Dastgiri, Hooman Nateghian","doi":"10.22038/IJP.2021.57861.4538","DOIUrl":"https://doi.org/10.22038/IJP.2021.57861.4538","url":null,"abstract":"BackgroundThe rate of neonatal mortality is one of the main indices of health, treatment, and development in societies. It reflects the quality of nutrition and life of mothers as well as the rate of healthcare services that mothers and children are provided with by societies. This study aimed to identify the factors affecting neonatal mortality by using a bagging neural network in Rapidminer Software. Materials and MethodsThe study was conducted on 8053 births (including 1605 death cases and 6448 control cases) all over Iran in 2015. Factors such as maternal risk factors, mother’s age, gestational age, child gender, birth weight, birth order, and congenital anomalies were utilized as the predictor variables of the bagging neural network. Some criteria including the area under the ROC curve, as well as the property and sensitivity of the bagging neural network, were compared with the neural network model. And the bagging neural network with 99.24% precision rate enjoyed better results in predicting those factors affecting neonatal mortality.ResultsOur suggested method revealed that gestational age is the most significant predictor factor of a neonate's status at birth time. Besides, 1-minute Apgar, need for resuscitation, 5-minute Apgar, birth weight, congenital anomalies, and birth order, as well as diabetes and preeclampsia in mothers, were identified as the most significant predictor factors after the gestational age.ConclusionFactors discovered in this study can be considered to decrease neonatal mortality. This can help the health of mothers’ community, optimize healthcare services, and development of societies.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44811892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and Presentation of Paediatric Coronavirus Disease 2019 in Lagos, Nigeria.","authors":"Abideen Salako, Oluwatosin Odubela, Tomilola Musari-Martins, Priscilla Ezemelue, Titilola Gbaja-Biamila, Babasola Opaneye, Ayorinde James, Osaga Oforomeh, Kazeem Osuolale, Adesola Musa, Emelda Chukwu, Nurudeen Rahman, Agatha David, Rosemary Audu, Oliver Ezechi, Babatunde Salako","doi":"10.1155/2021/2185161","DOIUrl":"10.1155/2021/2185161","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to describe the prevalence and clinical features of coronavirus disease 2019 (COVID-19) among children (≤18 years) evaluated for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection at a testing centre in Lagos, Nigeria. <i>Methodology</i>. This was a retrospective study. Data on the sociodemographic, clinical characteristics and SARS-CoV-2 results of participants at a modified drive-through centre for COVID-19 test sample collection over four months were retrieved from the electronic medical records (EMR). Data obtained were analyzed using SPSS version 22.0.</p><p><strong>Results: </strong>A total of 307 children (≤18 years) were evaluated in this review. The prevalence of SARS-CoV-2 infection among the paediatric population was 16.3%. The median age (interquartile range (IQR)) was 9 (4-14) years. Common symptoms reported by the positive cases were fever (40.0%), cough (32.9%), sore throat (17.1%), and runny nose (15.7%). The majority of the positive cases had mild symptoms. Fever and sore throat were associated with the positive cases.</p><p><strong>Conclusion: </strong>Fever and sore throat were associated with SARS-CoV-2 infection among our cohort which buttresses the need for a high level of suspicion and clinical acumen in the management of common febrile diseases in paediatric settings.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}