International Journal of Pediatrics最新文献

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Clinical Epidemiological Characteristics and Risk Factors for Severe Bronchiolitis Caused by Respiratory Syncytial Virus in Vietnamese Children. 越南儿童呼吸道合胞病毒致严重毛细支气管炎临床流行病学特征及危险因素分析
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9704666
Sang Ngoc Nguyen, Thuy Ngoc Thi Nguyen, Lam Tung Vu, Thap Duc Nguyen
{"title":"Clinical Epidemiological Characteristics and Risk Factors for Severe Bronchiolitis Caused by Respiratory Syncytial Virus in Vietnamese Children.","authors":"Sang Ngoc Nguyen,&nbsp;Thuy Ngoc Thi Nguyen,&nbsp;Lam Tung Vu,&nbsp;Thap Duc Nguyen","doi":"10.1155/2021/9704666","DOIUrl":"https://doi.org/10.1155/2021/9704666","url":null,"abstract":"<p><strong>Introduction: </strong>Bronchiolitis is the most prevalent cause of hospitalization in infants under the age of 12 months. The disease is caused by respiratory syncytial virus (RSV) infection, which can cause breathing difficulties and respiratory failure. Therefore, it is necessary to discover the risk factors of severe bronchiolitis to diagnose and treat promptly. This study is aimed at describing the epidemiological characteristics and clinical features of acute bronchiolitis caused by RSV and assessing the related factors to severe acute bronchiolitis in studied patients.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was carried out in Haiphong Children's Hospital, Haiphong, Vietnam, for one year, from October 1, 2016, to September 30, 2017. All bronchiolitis admissions < 2 years were included.</p><p><strong>Results: </strong>377 children were evaluated, including 261 boys and 116 girls; children under 6 months accounted for the highest proportion (57%), and 47 (12.5%) of all patients had severe disease. Wheezing was the main reason to be taken to the hospital 261 (69.2%). Clinical symptoms of acute bronchiolitis such as cough, tachypnea, and runny nose were found in all patients. Bronchiolitis cases increased in the winter-spring season, and the highest registered number of patients was 42 in March. Image of bronchiolitis on chest X-ray was found in all patients, and air trapping lung was found in 124 (32.9%) patients. The risk factors included age (≤6 months), low birth weight, preterm birth, nonbreastfeeding for the first six months, early weaning, and exposition to cigarette smoke increased the severe disease (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>The number of hospitalized infants with bronchiolitis caused by RSV has an upward trend during the winter-spring season (from October to March). This study confirms that age, preterm birth, breastfeeding under 6 months, history of exposure to cigarette smoking, low birth weight, having sibling(s) under five years old going to kindergarten, history of undergoing cesarean section, history of mechanical ventilation, poor living condition, and maternal education are 10 risk factors of severe bronchiolitis caused by RSV.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39908983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sexual health challenges in Iranian intellectually disabled adolescent girls: a qualitative study 伊朗智障少女的性健康挑战:一项定性研究
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-09 DOI: 10.22038/IJP.2021.59974.4659
Shadi Goli, M. Noroozi, M. Salehi
{"title":"Sexual health challenges in Iranian intellectually disabled adolescent girls: a qualitative study","authors":"Shadi Goli, M. Noroozi, M. Salehi","doi":"10.22038/IJP.2021.59974.4659","DOIUrl":"https://doi.org/10.22038/IJP.2021.59974.4659","url":null,"abstract":"Background: Sexual health is individuals’ ability to express their sexual needs within framework of society’s values without being afraid of sexually transmitted infections, unwanted pregnancies, violence and discrimination. Given the importance of sexual health in intellectually disabled adolescents, the present study was conducted to explore the sexual health challenges in intellectually disabled adolescent girls.\u0000Materials and Methods: The present qualitative study with content analysis approach was conducted on 48 participants including parents, teachers, healthcare providers and managers who were selected through purposeful sampling method in Isfahan, Iran. Data were gathered using semi-structured in-depth interviews, focus group discussions and field notes. Data were analyzed using conventional content analysis.\u0000Results: After data analysis, four sub-categories of “adolescent’s disability in understanding sexual matters and respecting social rules”, “the coexistence of psychiatric disorders and intellectual disability”, cultural taboos on sexual issues” and “teachers’ inability to deal with issues related to adolescent’s sexual health” were extracted. These sub-categories together formed the main category of “sexual health challenges”.\u0000Conclusion: Based on the results, designing comprehensive programs of sex education for intellectually disabled adolescent girls seems necessary. Also, empowering teachers to teach sexual health to these girls and their parents is of particular importance. Furthermore, the interaction between parents and school to maintain the sexual health of intellectually disabled adolescent girls could have an effective role in decreasing the rate of sexual abuse/harassment and their involvement in sexual relationships.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47160845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cognitive Determinants Predictors of Pediculosis Preventive Behaviors: Application of Health Belief Model 足部疾病预防行为的认知决定因素预测因素——健康信念模型的应用
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-09 DOI: 10.22038/IJP.2021.59233.4612
N. Shekarbeygi, M. Mirzaei-Alavijeh, F. Jalilian, B. Hamzeh, A. Almasi, M. Limoee, Negar Karimi, Masumeh Rezabigi, R. Pirouzeh, Seyyed Nasrollah Hosseini
{"title":"Cognitive Determinants Predictors of Pediculosis Preventive Behaviors: Application of Health Belief Model","authors":"N. Shekarbeygi, M. Mirzaei-Alavijeh, F. Jalilian, B. Hamzeh, A. Almasi, M. Limoee, Negar Karimi, Masumeh Rezabigi, R. Pirouzeh, Seyyed Nasrollah Hosseini","doi":"10.22038/IJP.2021.59233.4612","DOIUrl":"https://doi.org/10.22038/IJP.2021.59233.4612","url":null,"abstract":"Background: Pediculosis is still recognized as a worldwide infestation and is a major public health concern. The aim of this study was to determine the cognitive determinants predictors of pediculosis Preventive Behaviors (PPB) based on the Health Belief Model (HBM).\u0000Materials and Methods: This descriptive cross-sectional study was conducted among 193 girls’ high school students in the west of Iran, during 2019 that were selected by random sampling method. Participants filled out a self-administered questionnaire including the Background variables, PPB questionnaire, and HBM determinants. Data were analyzed by SPSS-22 software using Pearson correlation test and linear regression analysis.\u0000Results: The mean age of students was 12.72 years [SD: 0.60], ranged from 12 to 14 years. The mean score of PPB was 7.72 [SD: 2.23], ranged from 0 to 10. HBM determinants were accounted for 20% of the variation in PPB. The best predictors for PPB were perceived susceptibility (Beta: 0.303, P<0.001), perceived barriers (Beta: -0.217, P=0.004) and perceived self-efficacy (Beta: 0.158, P=0.040), respectively.\u0000Conclusion: It seems that the development and implementation of health promotion programs to increase susceptibility toward the risk of pediculosis, improve self-efficacy toward performing PPB, and reduce the barriers of students in adopting PPB may be usefulness results in order to prevent pediculosis.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45677711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Doppler Phonolyser in comparison with conventional statoscope in detecting and interpreting abnormal Heart murmurs in congenital and structural heart defects 多普勒消音仪与常规静视镜在先天性和结构性心脏缺陷中检测和解释异常心脏杂音的比较
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-09 DOI: 10.22038/IJP.2021.60620.4684
M. Naghibi, B. Alizadeh, S. Aminimoghadam
{"title":"Doppler Phonolyser in comparison with conventional statoscope in detecting and interpreting abnormal Heart murmurs in congenital and structural heart defects","authors":"M. Naghibi, B. Alizadeh, S. Aminimoghadam","doi":"10.22038/IJP.2021.60620.4684","DOIUrl":"https://doi.org/10.22038/IJP.2021.60620.4684","url":null,"abstract":"Background: Detecting heart murmurs by a newly invented Doppler Phonolyser machine is compared with the conventional stethoscope. \u0000Methods: In a cross-sectional study, a total of 112 patients referred to the pediatric cardiology clinic at were enrolled between Jan. 2017 and Jan. 2018. In step one, the patients were initially examined by a pediatric cardiologist, and then in step two,; they were randomly divided into two groups (A and B) and were blindly re-examined by a 2nd-year pediatric resident. In Group A (Statoscope group), heart auscultation was performed using only a conventional Statoscope whereas, in Group B (Statoscope + DPM), heart sounds were detected and analyzed using a stethoscope and Doppler Phonolyser Machine. In the third step, the diagnostic results made by the pediatric cardiologist, the pediatric residents in groups A and B were compared with the final diagnostic echocardiography made by a pediatric cardiologist. \u0000Results: Heart murmurs as one of the most common reasons for cardiologist referrals consist of about 65% of referrals to pediatric cardiologists. There was only a moderate correlation between a Stethoscope stethoscope and echocardiography to identify cardiac abnormality based on heart murmurs (56%), whilste there was a significant correlation between the diagnoses made by Doppler Phonolyser accompanied with the conventional statoscope when compared with the echocardiography results. \u0000Conclusion: Doppler Phonolyser is an innovative smart machine that could efficiently detect and analyze abnormal heart sounds and might play a role in more accurate and earlier diagnosis of congenital and structural heart defects by general physicians and non-cardiologist specialists, and may potentially reduce the mortality, morbidity, and cost of treatment as well as anxiety of the patient's family.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44790389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal Asphyxia and Its Associated Factors among Live Births in the Public Health Facilities of Bahir Dar City, Northwest Ethiopia, 2021. 埃塞俄比亚西北部巴希尔达尔市公共卫生机构活产婴儿的围产期窒息及其相关因素,2021 年。
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-08 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3180431
Magarsa Lami Dabalo, Simachew Animen Bante, Getahun Belay Gela, Selamawit Lake Fanta, Lemesa Abdisa Sori, Wondu Feyisa Balcha, Yomilan Geneti Muse, Tigist Derebe Tesfahun
{"title":"Perinatal Asphyxia and Its Associated Factors among Live Births in the Public Health Facilities of Bahir Dar City, Northwest Ethiopia, 2021.","authors":"Magarsa Lami Dabalo, Simachew Animen Bante, Getahun Belay Gela, Selamawit Lake Fanta, Lemesa Abdisa Sori, Wondu Feyisa Balcha, Yomilan Geneti Muse, Tigist Derebe Tesfahun","doi":"10.1155/2021/3180431","DOIUrl":"10.1155/2021/3180431","url":null,"abstract":"<p><strong>Background: </strong>Birth asphyxia is a serious clinical problem of newborn babies, which occurs due to impaired blood-gas exchange and results in hypoxemia. Despite improvements in the diagnosis and management of perinatal asphyxia, it has become the leading cause of admission and neonatal mortality, especially in developing countries.</p><p><strong>Objective: </strong>This study was aimed at assessing factors associated with perinatal asphyxia among live births in the public health facilities of Bahir Dar city, Northwest Ethiopia, 2021.</p><p><strong>Method: </strong>Health facility-based cross-sectional study was employed from April 1-30/2021 in the public health facilities of Bahir Dar city among 517 mother-newborn pairs. The data were collected by systematic random sampling technique, entered by using Epi data 3.1, and analyzed using SPSS 25.0 version. Bivariate and multivariable logistic regression analyses were employed to estimate the crude and adjusted odds ratio with a confidence interval of 95% and a <i>P</i> value of less than 0.05 considered statistically significant. Frequency tables, figures, and descriptive summaries were used to describe the study variables.</p><p><strong>Result: </strong>In this study, 21.7% (95% CI: 18.2%-25.5%) of the newborns had perinatal asphyxia. Malpresentation (AOR = 4.06, 95%CI = 2.08-7.94), uterotonic drug administration (AOR = 2.78, 95%CI = 1.67-4.62), meconium-stained amniotic fluid (AOR = 4.55, 95%CI = 2.66, 7.80), night time delivery (AOR = 1.91, 95%CI = 1.17, 3.13), and preterm delivery (AOR = 3.96, 95%CI = 1.98, 7.89) were significantly associated with perinatal asphyxia. <i>Conclusion and Recommendation</i>. In the present study, the proportion of perinatal asphyxia was high. To mitigate this problem, there is a need to focus on early identification of the risk factors like fetal malpresentation, preterm labor/delivery, and managing them appropriately. Administering uterotonic drugs should be based on indication with close supervision.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39900367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epiglottitis in four – year- old boy caused by COVID-19 infection COVID-19感染致四岁男童会厌炎
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-08 DOI: 10.22038/IJP.2021.59266.4618
Mehran Karimi, Abdolhamid Jafari Nodoushan, S. J. Sayedi, Ali Shahzeidi
{"title":"Epiglottitis in four – year- old boy caused by COVID-19 infection","authors":"Mehran Karimi, Abdolhamid Jafari Nodoushan, S. J. Sayedi, Ali Shahzeidi","doi":"10.22038/IJP.2021.59266.4618","DOIUrl":"https://doi.org/10.22038/IJP.2021.59266.4618","url":null,"abstract":"Introduction: Epiglottitis is an inflammatory disease involving the epiglottis, vallecula, aritenoid cartilage, and aryepiglottic wrinkles. Acute epiglottitis is relatively rare but can quickly lead to life-threatening airway obstruction. Diagnosis of epiglottitis is clinical, but radiography and direct vision of the epiglottis can also help with the diagnosis. Clinical manifestations of epiglottitis include fever, sore throat, and in the event of imminent airway obstruction, also may present with muffled sound, falls, tripod position, and stridor. Epiglottitis can be caused by some bacterial agents or viruses such as adenovirus and measles.COVID-19 was first detected in December 2019 in a group of patients with severe respiratory symptoms in Hubei Province, China. Common symptoms include fever, cough, fatigue, difficulty breathing, and loss of smell and taste. Although COVID-19 disease has a variety of manifestations, only one case of epiglottitis following COVID-19 disease has been reported in adults. \u0000\u0000Case presentation: The patient, a 4-year-old boy, came to our center and the patient's family complained of shortness of breath and progressive lethargy of the child 10 days ago. Since last week, he has been sleeping in a sitting position due to the aggravation of shortness of breath. On physical examination, respiratory distress, tachypnea, subcostal retraction, tail stridor, and crackle was heard in both lungs. Diagnosed with suspected bronchoscopy epiglottitis, a large, swollen, and cherry-red epiglottis was observed. Based on the patient's history of respiratory symptoms and the prevalence of COVID-19, a reverse pharyngeal polymerase (RT-PCR) transcript test was requested for COVID-19 and the COVID-19 infection was positive. \u0000\u0000Conclusion: In this article, we reported an 4-year-old child with epiglottitis in the context of COVID19.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48923621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effectiveness of Swimming Training on Reducing Coping Behaviors, Cognitive Problems and Inattention of Elementary School Hyperactive Girls 游泳训练对减少小学多动女生应对行为、认知问题及注意力不集中的效果
IF 2.1
International Journal of Pediatrics Pub Date : 2021-11-01 DOI: 10.22038/IJP.2021.59748.4649
M. Salehian, Maryam Golabchi
{"title":"The Effectiveness of Swimming Training on Reducing Coping Behaviors, Cognitive Problems and Inattention of Elementary School Hyperactive Girls","authors":"M. Salehian, Maryam Golabchi","doi":"10.22038/IJP.2021.59748.4649","DOIUrl":"https://doi.org/10.22038/IJP.2021.59748.4649","url":null,"abstract":"Background: The increase of ADHD affects family relations and the mental health of family members as well as the child himself. The main purpose of this study was to determine the effectiveness of swimming training on reducing coping behaviors, cognitive problems and inattention of Elementary School female students with hyperactivity disorder.Method: The present applied research follows a descriptive-analytical method and a pre-post test experimental-control design. The participants included children with signs of hyperactivity (age=7.2±1.6 years) from welfare centers of Tabriz. The participants were randomly assigned to two experimental (n=15) and control (n=15) groups. Before the initiation of the training program, the Conners questionnaire (parent form) was completed by the parents. The training was held every week in two 45-minute sessions for 2 months. At the end of the training, a practical test was performed according to the standards of the province sports board, and the scores were recorded on special sheets. After completing the exercises and testing, the Conners questionnaire for parents was again distributed among the parents. T tests were used for analyzing the data.Results: The results showed that swimming had a significant positive effect on reducing coping behaviors, cognitive problems and inattention of elementary school hyperactive girls.Conclusion: Exercise strengthens the primary atrial nervous system and promotes superior brain functions such as motor skills and integration in action, which can reduce social maladaptation by creating a conducive environment for increased self-confidence and empowerment","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42981916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Hematological indices in differentiation between iron deficiency anemia and beta-thalassemia trait 区分缺铁性贫血和β地中海贫血的血液学指标
IF 2.1
International Journal of Pediatrics Pub Date : 2021-10-30 DOI: 10.22038/IJP.2021.59644.4644
Nagwan I Rashwan, A. Ahmed, Mohammed H. Hassan, Maha E. Mohammed, A. Bakri
{"title":"Hematological indices in differentiation between iron deficiency anemia and beta-thalassemia trait","authors":"Nagwan I Rashwan, A. Ahmed, Mohammed H. Hassan, Maha E. Mohammed, A. Bakri","doi":"10.22038/IJP.2021.59644.4644","DOIUrl":"https://doi.org/10.22038/IJP.2021.59644.4644","url":null,"abstract":"Background:Mild microcytic hypochromic anemias caused by iron deficiency (IDA) and beta-thalassemia trait (βTT) continue to be problematic and a significant threat to society, particularly in relatively poor developing countries.The goal of this study was to use accuracy approach to improve the diagnostic function of eight different prejudiced indices in Egyptian pediatric patients with microcytic anaemia.\u0000Materials and methods: Eight discrimination indices diagnostic performance presented in previous studies were introduced to analyze the differences between β-βTTand IDA among Egyptian paediatric patients by using evaluation metrics calculated from RBC indices by various mathematical formulae. CBC , iron study and hemoglobin electrophoresis were performed to all included participants.\u0000Results: A total of 300 Egyptian paediatric patients with βTT or IDA were enrolled. The Mentzer and Ehsani index exhibited the highest diagnostic accuracy (100%) followed by Sirdah (97.5%), Sirvistava (95%), MDHL (92.5%) Green & King, Recierca, (90%), and Matos(70%).Indices with AUCs greater than 0.8, such as Mentzer, Ehsani, and Sirdah, had very valuable predictive accuracy in distinguishing between β-TT and IDA.\u0000Conclusion: Although Hb electrophoresis is the gold standard for diagnosing βTT, in developing countries, the Mentzer index, followed by the Ehsani and Sirdah indices, could be used as a simple , cheap method to distinguish βTT from IDA in pediatric patients with mild microcytic hypochromic anaemia.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44980495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Use of Probiotics in Infants with Cow’s Milk Allergy: A randomized, placebo controlled trial 对牛奶过敏的婴儿使用益生菌:一项随机安慰剂对照试验
IF 2.1
International Journal of Pediatrics Pub Date : 2021-10-28 DOI: 10.22038/IJP.2021.58744.4591
H. Karami, Sahar Borna, F. Hosseinzadeh, Elahe Mahmoodi, B. Aghaee, M. S. Rezai
{"title":"Use of Probiotics in Infants with Cow’s Milk Allergy: A randomized, placebo controlled trial","authors":"H. Karami, Sahar Borna, F. Hosseinzadeh, Elahe Mahmoodi, B. Aghaee, M. S. Rezai","doi":"10.22038/IJP.2021.58744.4591","DOIUrl":"https://doi.org/10.22038/IJP.2021.58744.4591","url":null,"abstract":"Background: One of the most common food allergies in infants is cow’s milk allergy (CMA). There is no available effective therapeutic strategy for this issue. It's important to develop effective approaches to reduce the risk of cow’s milk allergy. The purpose of this study was to investigate the effect of probiotics in infants with cow’s milk protein intolerance.\u0000Materials and methods: This study was a randomized clinical trial in full-term infants with CMA diagnosis. These patients were divided into case and control groups (receiving placebo and probiotic). Clinical symptoms such as diarrhea, abdominal pain and etc. were evaluated in 2, 4, 8, 12 and 16 weeks after receiving probiotics.\u0000Results: During 16 weeks of the study, a significant decrease was observed in clinical and paraclinical findings in both groups. There was a statistically significant decrease in times of mucosal, bloody and daily defecation of patients on 4th, 8th and 12th week. Also, a significant difference was found between both groups for diarrhea and abdominal cramps from the 4th week.\u0000Conclusion: The consumption of probiotics for a short time in infants with CMA significantly decreased the clinical and paraclinical symptoms.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48349661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Changes in Electrocardiogram Intervals During Treatment with Gonadotropin-Releasing Hormone Agonists in Patients with Precocious Puberty 促性腺激素释放激素激动剂治疗青春期前期患者心电图间期变化的评价
IF 2.1
International Journal of Pediatrics Pub Date : 2021-10-27 DOI: 10.22038/IJP.2021.58524.4593
A. Bagherzadeh, S. Shiva, Mahmoud Samadi, Seyyed-Reza Sadat-Ebrahimi
{"title":"Evaluation of Changes in Electrocardiogram Intervals During Treatment with Gonadotropin-Releasing Hormone Agonists in Patients with Precocious Puberty","authors":"A. Bagherzadeh, S. Shiva, Mahmoud Samadi, Seyyed-Reza Sadat-Ebrahimi","doi":"10.22038/IJP.2021.58524.4593","DOIUrl":"https://doi.org/10.22038/IJP.2021.58524.4593","url":null,"abstract":"Introduction: GnRH agonists are the standard treatment for precocious puberty. Studies on the side effects of these drugs in adults have shown that these drugs may cause changes in ECG and some cardiovascular effects; however, few studies have evaluated these effects in children. This study aims to investigate the effect of these drugs on ECG intervals in children with precocious puberty.\u0000Methods & Materials: In this study with a pre-post study design 50 children with precocious puberty referred to the endocrinology clinic of Tabriz Children's Hospital in 2019 for receiving GnRH agonists were included. From all patients, ECG was obtained before starting treatment and then 6, 12, and 18 weeks later and PR, QRS, and QTc intervals were extracted from ECG records.\u0000Results: The mean age of included patients was 91±9 months including 48 (96%) girls and 2 (4%) boys. Triptorelin (GnRH agonist) was administered for all patients with standard protocol. Comparison of pre- and post-treatment ECG intervals showed that the drug did not cause a significant change in PR (p = 0.535) and QTc (p = 0.250) intervals, whilst there was a significant increase in QRS interval after treatment (p = 0.001). \u0000Conclusion: The use of GnRH agonists in children can lead to some changes in ECG records by increasing in QRS intervals and ECG could be used as a tool to detect these changes. Further studies are also needed to identify ECG changes in larger sample sizes and longer intervals.","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49598583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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