The evaluation of Left atrial to aortic root after PDA closure in children

Ductus arteriosus(DA) is a vascular structure that makes a link between the proximal descending aorta and main pulmonary artery near the origin of the left pulmonary artery. The present study aimed to assess the changes of LA/Ao after PDA closure in children. Methods This cross-sectional study was performed on 635 children with PDA in the Ali Asghar clinic, Zahedan-Iran from 2003 to 2019. The children followed for at least one year after discharge from the hospital after intervention. Analyzed performed by SPSS 20.00 with 0.05 as significant error. Results Decreasing growth rates of LA/Ao were 24% and 10% in the first and second 6 months after intervention compared with the baseline values. During the first 6 months after intervention, the percentages of LA/Ao reduction were 23%, 25% and 22% in small, medium and large PDA when these percentages were 7%, 13% and 16% during the second 6 months after intervention respectively. Regarding intervention, the percentages were 25%, 24%, 24% and 24% in PDA that closed by medication, surgery, device occluded and VATS in the first six months after intervention. The percentages were 9%, 10%, 11% and 9% for the second 6 months after intervention. The percentages were 24%, 24% and 21% in those PDA with residuals, no complication and PH in the first six months after intervention. This pattern was 8%, 9% and 16.6% for the second 6 months after intervention. Conclusion Concluded that LA/Ao had the highest decrease during the first six months after intervention such that moderate PDA size or those PDA who had medication as intervention or those with residuals complication had the highest percentages of reduction.