International Journal of Pediatrics最新文献

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Outcomes of Noninvasive Positive Pressure Ventilation via RAM Cannula in Pediatric Intensive Care: A Preliminary Report. RAM插管无创正压通气在儿科重症监护中的效果:初步报告。
IF 2.2
International Journal of Pediatrics Pub Date : 2026-06-23 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/8130440
Humaira Mustafa, Muhammad Uzair, Sidra Khan, Qalab Abbas
{"title":"Outcomes of Noninvasive Positive Pressure Ventilation via RAM Cannula in Pediatric Intensive Care: A Preliminary Report.","authors":"Humaira Mustafa, Muhammad Uzair, Sidra Khan, Qalab Abbas","doi":"10.1155/ijpe/8130440","DOIUrl":"10.1155/ijpe/8130440","url":null,"abstract":"<p><strong>Background: </strong>Experience in the use of noninvasive positive pressure ventilation (NIPPV) via RAM cannula in the Pediatric Intensive Care Unit (PICU) is limited.</p><p><strong>Objective: </strong>The objective of this study is to describe the characteristics, outcomes, and complications of patients receiving NIPPV via RAM cannula in our PICU.</p><p><strong>Methods: </strong>A 12-month (Jan-Dec 2024) retrospective cohort study included 60 children (1 month-18 years) who received NIPPV via RAM cannula. Patients undergoing elective intubation, with do-not-resuscitate orders or with incomplete records, were excluded. Initial NIPPV settings were PEEP 5-12 cm H<sub>2</sub>O, inspiratory pressure 15-28 cm H<sub>2</sub>O, and FiO<sub>2</sub> titrated to maintain SpO<sub>2</sub> ≥ 92%. NIPPV failure was defined as escalation to invasive ventilation. Data were analyzed using STATA.</p><p><strong>Result: </strong>A total of 60 were included with a median age of 15.6 months (IQR 7-41.5). Admitting diagnosis were respiratory illnesses (36; 60%), cardiac disease (9; 15%), and sepsis with MODS (6; 10%). NIPPV indications include respiratory distress in 42 (70%) patients and postextubation support in 18 (30%) patients. Success was achieved in 44 patients (73.3%). Failure was associated with comorbidities (adjusted OR 0.024, <i>p</i> = 0.010), higher PRISM III scores (adjusted OR 0.745, <i>p</i> = 0.008), higher PEEP (9.8 vs. 8.4 cm H<sub>2</sub>O, <i>p</i> = 0.018), and FiO<sub>2</sub> (90.6% vs. 60.9%, <i>p</i> < 0.001). A higher SF ratio was associated with success (189 vs. 136, <i>p</i> < 0.001). Failures had more pneumothorax (31% vs. 2.3%, <i>p</i> = 0.001), longer PICU stay. (18.3 vs. 8.9 days, <i>p</i> < 0.001), and 50% mortality rate, with no deaths among successful cases.</p><p><strong>Conclusion: </strong>NIPPV is an effective respiratory support modality in the PICU. Predictors of success are lower illness severity, no comorbidities, and better oxygenation.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"8130440"},"PeriodicalIF":2.2,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13288053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seventy-Two-Hour Emergency Department Revisits in the Pediatric Population at King Abdullah Specialist Children's Hospital, Riyadh, Saudi Arabia: A Morbidity Analysis. 沙特阿拉伯利雅得阿卜杜拉国王专科儿童医院儿科72小时急诊科就诊情况:发病率分析
IF 2.2
International Journal of Pediatrics Pub Date : 2026-06-20 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/1897862
Mohammed AlAteeq, Shaden Althuwaini, Haya Alsubaie, Lulwah Al-Alshaikh, Ghaid Alotaibi, Sarah Alghuraybi, Aamir Omair
{"title":"Seventy-Two-Hour Emergency Department Revisits in the Pediatric Population at King Abdullah Specialist Children's Hospital, Riyadh, Saudi Arabia: A Morbidity Analysis.","authors":"Mohammed AlAteeq, Shaden Althuwaini, Haya Alsubaie, Lulwah Al-Alshaikh, Ghaid Alotaibi, Sarah Alghuraybi, Aamir Omair","doi":"10.1155/ijpe/1897862","DOIUrl":"10.1155/ijpe/1897862","url":null,"abstract":"<p><strong>Background: </strong>Recent data suggest that pediatric emergency department (ED) revisits within 72 h have increased globally, particularly during recent respiratory illness surges, potentially straining healthcare resources. This study is aimed at identifying reasons for these revisits and describe management outcomes for children aged 0-14 years.</p><p><strong>Methods: </strong>A cross-sectional chart review was conducted at a tertiary hospital in Riyadh from March 1, 2022, to April 30, 2023. The study included Saudi nationals aged 0-14 years who revisited the ED within 72 h of their initial visit; noncitizen children were excluded. Data captured included demographics, medical history, and details of both initial and revisits (reason for visit, assessment, and management).</p><p><strong>Results: </strong>Three hundred Saudi children were included; 31% were aged 0-3 years, and approximately 60% were male. Twenty-six percent had chronic medical conditions, with asthma exacerbation being most common (12%). Persistent cough accounted for the highest proportion of revisits (34%). Antibiotics were prescribed in 28% of initial visits and 29% of revisits. Reassurance was provided in 27% of initial visits and 27% of revisits. The 0-3 year age group showed significantly higher rates of admission and discharge.</p><p><strong>Conclusion: </strong>Persistent respiratory symptoms (especially cough and dyspnea) were the most frequent reasons for pediatric ED revisits, with asthma as the prevalent chronic condition. Improving initial diagnosis and management is essential to reduce avoidable revisits. Future research comparing presurge and postsurge periods could clarify if revisit reasons change over time.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"1897862"},"PeriodicalIF":2.2,"publicationDate":"2026-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Depression and Its Association With Child Undernutrition in Urban Ethiopia. 埃塞俄比亚城市孕产妇抑郁及其与儿童营养不良的关系。
IF 2.2
International Journal of Pediatrics Pub Date : 2026-06-16 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/7491512
Sitota Gebremelak, Tefera Darge Delbiso
{"title":"Maternal Depression and Its Association With Child Undernutrition in Urban Ethiopia.","authors":"Sitota Gebremelak, Tefera Darge Delbiso","doi":"10.1155/ijpe/7491512","DOIUrl":"10.1155/ijpe/7491512","url":null,"abstract":"<p><p>Maternal depression is one of several multidimensional factors that influence children's nutritional status. However, research in this area remains limited in urban poverty settings, where residents are often assumed to have better access to socioeconomic and health services. We estimated the prevalence of maternal depression and assessed its association with undernutrition among children aged 12-36 months of economically disadvantaged mothers in urban Ethiopia. A cross-sectional survey was conducted to collect data from 627 mother-child pairs in selected urban areas of Ethiopia: Adama, Addis Ababa, Debre Birhan. Maternal depression was measured using Patient Health Questionnaire-9 (PHQ-9) score, whereas child nutritional status was measured using anthropometric methods. Background characteristics of the study were summarized using percentages and averages. Binary logistic regression was used to assess the association between maternal depression and undernutrition, adjusting for confounders. The prevalence of maternal depression was 16.0% (95% CI: 13.3%-19.0%), while stunting among children aged 12-36 months was 52.7% (95% CI: 48.7%-56.7%). Maternal depression was significantly associated with child stunting after adjusting for covariates but showed no significant association with wasting or underweight. Children of mothers exhibiting depression symptoms had 2.21 times higher odds of being stunted (95% CI: 1.33-3.68) compared with those of nondepressed mothers. These findings underscore the critical need for integrated public health interventions that incorporate maternal mental health into child nutrition programs, alongside strengthened community advocacy and education on maternal mental health. Childcare support with income-generating activities for women can boost women's income, provide greater peace of mind, and support improved mental well-being.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"7491512"},"PeriodicalIF":2.2,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13271042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148273811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative and Long-Term Functional Outcomes of Children With Early Diagnosis Versus Late Diagnosis of Hirschsprung's Disease: A 30-Year Monocentric Retrospective Study. 早期诊断与晚期诊断先天性巨结肠病儿童围手术期和远期功能结局:一项30年单中心回顾性研究
IF 2.2
International Journal of Pediatrics Pub Date : 2026-06-12 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/5593406
Kamal El Haissoufi, Francesca Nascimben, Anne Lehn, Isabelle Chevalier, Raphael Moog, Rossella Angotti, Francesco Molinaro, François Becmeur, Isabelle Talon
{"title":"Perioperative and Long-Term Functional Outcomes of Children With Early Diagnosis Versus Late Diagnosis of Hirschsprung's Disease: A 30-Year Monocentric Retrospective Study.","authors":"Kamal El Haissoufi, Francesca Nascimben, Anne Lehn, Isabelle Chevalier, Raphael Moog, Rossella Angotti, Francesco Molinaro, François Becmeur, Isabelle Talon","doi":"10.1155/ijpe/5593406","DOIUrl":"10.1155/ijpe/5593406","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare the perioperative course and long-term functional outcomes of children with early and late diagnosis of Hirschsprung's disease (HD).</p><p><strong>Methods: </strong>This retrospective study included patients affected by HD who underwent pull-through between 1984 and 2015. Patients were classified into two groups: early diagnosis of HD (EDHD) before 1 year of age and late diagnosis of HD (LDHD) after 1 year. Functional outcomes at 3, 6, and 9 years after surgery were analyzed.</p><p><strong>Results: </strong>One hundred and five patients, 83.8% with EDHD and 16.2% with LDHD. Abdominal distension and vomiting were the main presenting symptoms of EDHD, whereas chronic constipation was the primary symptom of LDHD. Preoperative intestinal obstruction occurred in 59.1% of EDHD versus 5.9% of LDHD (<i>p</i> < 0.0001). Diverting colostomy was performed in 31.8% of EDHD versus 5.9% in LDHD (<i>p</i> = 0.03). Anal strictures needing anal dilatation occurred in 30.7% of EDHD versus 5.9% in LDHD (<i>p</i> = 0.03). At 3 years of follow-up, there was a statistical difference in terms of constipation (10% in EDHD vs. 23.5% in LDHD; <i>p</i> = 0.04), but not in terms of soiling (30.7% vs. 29.4%; <i>p</i> = 0.65); 9 years after surgery, comparable results were shown in terms of both constipation and soiling.</p><p><strong>Conclusion: </strong>Long-term functional outcome is generally comparable between patients with EDHD and LDHD.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"5593406"},"PeriodicalIF":2.2,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13263226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healing Beyond Words: A Randomized Controlled Trial of Sandplay and Art Therapies for PTSD Among Syrian Refugee Children in Jordan. 治愈超越语言:一项随机对照试验,沙盘游戏和艺术疗法治疗约旦叙利亚难民儿童的创伤后应激障碍。
IF 2.2
International Journal of Pediatrics Pub Date : 2026-06-10 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/7636252
Abdulqudos Al-Fakih, Abdallah Alzoubi, Ahmad Alrawashdeh, Jomana W Alsulaiman, Saleh A Ba-Shammakh, Adi Khasawneh, Karin Dannecker, Khalid A Kheirallah
{"title":"Healing Beyond Words: A Randomized Controlled Trial of Sandplay and Art Therapies for PTSD Among Syrian Refugee Children in Jordan.","authors":"Abdulqudos Al-Fakih, Abdallah Alzoubi, Ahmad Alrawashdeh, Jomana W Alsulaiman, Saleh A Ba-Shammakh, Adi Khasawneh, Karin Dannecker, Khalid A Kheirallah","doi":"10.1155/ijpe/7636252","DOIUrl":"10.1155/ijpe/7636252","url":null,"abstract":"<p><strong>Background: </strong>Expressive arts provide nonverbal therapeutic tools that can help children with post-traumatic stress disorder (PTSD) overcome language and cultural barriers. This study compared the effectiveness of sandplay therapy and art therapy in reducing PTSD symptom severity among Syrian refugee children living in noncamp, host community settings in Jordan.</p><p><strong>Methodology: </strong>We conducted a three-arm, parallel-group, randomized controlled trial involving 102 Syrian refugee children (aged 5-13 years) with clinically diagnosed PTSD. Participants were randomly assigned to sandplay therapy (<i>n</i> = 32), art therapy (<i>n</i> = 42), or standard counseling (control, <i>n</i> = 28). Each group received one session per week for 12 weeks. The primary outcome was the total score on Part IV of the Arabic version of the Harvard Trauma Questionnaire (HTQ), assessed at baseline and postintervention. Between- and within-group analyses, analysis of variance, and linear regression were used to evaluate changes in PTSD severity.</p><p><strong>Results: </strong>Baseline characteristics were comparable across groups, though severe PTSD was more prevalent in the sandplay group (40.6%), compared to the art therapy (11.9%) and control (25.0%) groups. After 12 weeks, sandplay therapy resulted in the greatest reduction in PTSD symptom severity (mean HTQ score difference: -22.4, <i>p</i> < 0.001), followed by art therapy (-10.8, <i>p</i> < 0.001) and standard counseling (-2.1, <i>p</i> = 0.002). Between-group analyses confirmed sandplay's superior efficacy over both art therapy and standard counseling (<i>p</i> < 0.001), whereas art therapy was significantly more effective than control.</p><p><strong>Conclusion: </strong>Both sandplay and art therapies significantly improved PTSD symptoms in conflict-affected children, with sandplay demonstrating the greatest impact. These findings underscore the effectiveness of expressive, nonverbal interventions in addressing conflict-related trauma among refugee populations and support their integration into comprehensive mental health programs.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT06984198.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"7636252"},"PeriodicalIF":2.2,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13250694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
School-Related Stressors, Pain Outcome Measures and Extremely Low Health-Related Quality of Life in a Representative Sample of Hungarian Adolescents With Functional Abdominal Pain Disorders. 匈牙利功能性腹痛青少年代表性样本中的学校相关压力源、疼痛结局测量和极低健康相关生活质量
IF 2.2
International Journal of Pediatrics Pub Date : 2026-05-27 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/9964179
János Major, Adrienn Vargay, Szilvia Ádám
{"title":"School-Related Stressors, Pain Outcome Measures and Extremely Low Health-Related Quality of Life in a Representative Sample of Hungarian Adolescents With Functional Abdominal Pain Disorders.","authors":"János Major, Adrienn Vargay, Szilvia Ádám","doi":"10.1155/ijpe/9964179","DOIUrl":"10.1155/ijpe/9964179","url":null,"abstract":"<p><strong>Background: </strong>Despite the growing body of evidence on paediatric chronic pain, there is a paucity of studies focusing on school stressors, internationally recommended core outcome measures for chronic pain and chronic disabling pain in adolescents with functional abdominal pain disorders (FAPDs).</p><p><strong>Methods: </strong>We conducted a cross-sectional, nationwide study in a representative sample of 657 adolescents (51.1% girls, median age 15.0 [IQR 13.0-17.0] years) including 62 adolescents with FAPDs. We used study-specific questionnaires to explore school stressors, core outcome measures of pain and other somatic symptoms. We deployed multiple regression analyses to identify predictors of extremely low health-related quality of life (HRQOL).</p><p><strong>Results: </strong>Amongst adolescents with FAPDs, school stressors and frequent harassment were significantly more prevalent; extraintestinal pain was reported by 54.8%, and 11.3% have reported continuous or daily pain. Significantly lower HRQOL, a higher number of missed school days and more frequent use of pain medication were identified. In the FAPD group, 14.5% (<i>N</i> = 9) adolescents reported extremely low HRQOL, which was associated with verbal harassment, multisite pain and higher frequency of pain on multivariate analysis.</p><p><strong>Conclusions: </strong>Our results suggest that a portion of adolescents with FAPD may suffer from chronic disabling pain with extremely low HRQOL. These results may guide more accurate diagnostics of FAPDs.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"9964179"},"PeriodicalIF":2.2,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13213717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148058149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of De Novo ZBTB18 Variant in a Patient With Global Developmental Delay, Seizures, and Juvenile Facies. 在一名整体发育迟缓、癫痫发作和幼年相患者中发现ZBTB18突变体
IF 2.2
International Journal of Pediatrics Pub Date : 2026-05-23 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/7226289
Yan Wu, Bei Li, Liang Liu, Yan Wang, Dongjing Li
{"title":"Identification of De Novo <i>ZBTB18</i> Variant in a Patient With Global Developmental Delay, Seizures, and Juvenile Facies.","authors":"Yan Wu, Bei Li, Liang Liu, Yan Wang, Dongjing Li","doi":"10.1155/ijpe/7226289","DOIUrl":"10.1155/ijpe/7226289","url":null,"abstract":"<p><strong>Background: </strong><i>ZBTB18</i> encodes a C2H2-type zinc finger protein that acts as a transcriptional repressor and is essential for neurodevelopment. Variants in <i>ZBTB18</i> are associated with intellectual developmental disorder, autosomal dominant 22 (MRD22). Patients with MRD22 present with intellectual disability (ID), corpus callosum anomalies, hypotonia, microcephaly, growth problems, epilepsy, and variable facial dysmorphism.</p><p><strong>Methods: </strong>Whole exome sequencing (WES) was performed to identify the molecular etiology. Sanger sequencing was used to validate the variant. Clinical assessments were conducted using brain magnetic resonance imaging (MRI) and electroencephalogram (EEG).</p><p><strong>Results: </strong>Our patient presented with sleep-associated focal motor seizures, characterized by right-sided clonic movements with impaired consciousness, accompanied by atypical absence seizures. She also exhibited global developmental delay, unexplained ankle hypertonia, and unique juvenile facies (characterized by a lack of complex emotional expression, a fixed gaze, and an overall immature facial gestalt). Video EEG demonstrated hypsarrhythmia, whereas brain MRI revealed no structural abnormalities at the age of 2.5 years. The patient received antiepileptic therapy, and seizure control was successfully achieved following perampanel treatment. A de novo <i>ZBTB18</i> variant (NM_205768.3: c.1474delA (p.Arg492Aspfs∗11)) was identified in our patient.</p><p><strong>Conclusion: </strong>To conclude, we report a de novo <i>ZBTB18</i> frameshift variant (NM_205768.3: c.1474delA (p.Arg492Aspfs∗11)) in a female patient presenting with global developmental delay, epilepsy, ankle hypertonia, and unique juvenile facies. Notably, seizures were ultimately controlled with perampanel, which may provide a therapeutic insight for drug-resistant epilepsy in MRD22. Our study expands the phenotypic and genetic spectrum of <i>ZBTB18</i> and provides novel insights into the clinical management of MRD22.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"7226289"},"PeriodicalIF":2.2,"publicationDate":"2026-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13197796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Double Burden: Understanding the Impact of Malnutrition on Childhood Cancer Outcomes in Resource-Limited Settings. 双重负担:了解营养不良对资源有限环境下儿童癌症结局的影响。
IF 2.2
International Journal of Pediatrics Pub Date : 2026-05-11 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/8860996
Michael Asare-Baah, Michael Lauzardo
{"title":"The Double Burden: Understanding the Impact of Malnutrition on Childhood Cancer Outcomes in Resource-Limited Settings.","authors":"Michael Asare-Baah, Michael Lauzardo","doi":"10.1155/ijpe/8860996","DOIUrl":"10.1155/ijpe/8860996","url":null,"abstract":"<p><p>Childhood cancer disproportionately affects low- and middle-income countries (LMICs), where over 80% of cases occur, and malnutrition affects approximately 70% of pediatric oncology patients, substantially compromising treatment tolerance, immune function, and survival. This review integrates current evidence on the impact of malnutrition in LMICs, evaluates assessment methodologies and interventions, and identifies knowledge gaps that hinder optimal nutritional care. The A-B-C-D (anthropometric, biochemical, clinical, and dietary assessments) framework provides a systematic assessment, with mid-upper arm circumference and handgrip dynamometry offering practical evaluation in resource-limited settings. Prealbumin is the most sensitive early biochemical marker (54%-87% sensitivity vs. 7.4%-45.8% for albumin), and nutritional screening tools like SCAN demonstrate high validity for risk identification (> 80% sensitivity and specificity). Interventions such as ready-to-use therapeutic foods improved weight gain (77.8% vs. 64.2%) and reduced severe infections (10.6% vs. 31%) in trials. We emphasize a multidisciplinary approach and research priorities centered on standardized assessments, long-term effects of malnutrition, and culturally appropriate nutritional programs for LMICs.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"8860996"},"PeriodicalIF":2.2,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13159538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147935336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Bariatric Surgery on Newborn Growth Parameters. 减肥手术对新生儿生长参数的影响。
IF 2.2
International Journal of Pediatrics Pub Date : 2026-04-30 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/1763085
Rayen Aoun, Souheil Hallit, Georges Nicolas
{"title":"Impact of Bariatric Surgery on Newborn Growth Parameters.","authors":"Rayen Aoun, Souheil Hallit, Georges Nicolas","doi":"10.1155/ijpe/1763085","DOIUrl":"10.1155/ijpe/1763085","url":null,"abstract":"<p><strong>Objective: </strong>We are aimed at assessing the influence of different bariatric procedures on fetal growth and risk of small-for-gestational-age (SGA) infants.</p><p><strong>Methods: </strong>This retrospective study was conducted at one hospital in Lebanon. A group of pregnant women with a history of bariatric procedures (<i>n</i> = 36) was compared with a control group of women without prior bariatric surgery (<i>n</i> = 98). Then, the study group was further stratified according to the type of procedure into purely restrictive and mixed bariatric techniques.</p><p><strong>Results: </strong>Pregnancies following bariatric surgery were associated with significantly lower mean birthweight, shorter birth length, and smaller head circumference, along with a decreased likelihood of large-for-gestational-age infants. In contrast, the risk of SGA infants was higher.</p><p><strong>Conclusion: </strong>Our findings suggest a potential association between pregnancy following bariatric surgery and an increased risk of SGA infants. These results underscore the importance of providing appropriate preoperative counseling to women of reproductive age considering such procedures. For those with a history of bariatric surgery, optimizing nutritional status prior to conception and ensuring close monitoring of maternal nutrition and fetal growth throughout pregnancy are crucial. Preventive strategies aimed at reducing the risk of SGA outcomes in this population should be emphasized.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"1763085"},"PeriodicalIF":2.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13131062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newborn Vitals in the First 10 min Do Not Differ With Mode of Delivery. 新生儿前10分钟的生命体征与分娩方式无关。
IF 2.2
International Journal of Pediatrics Pub Date : 2026-04-11 eCollection Date: 2026-01-01 DOI: 10.1155/ijpe/7764047
Archana S Nimbalkar, Minal Patel, Krishna Mori, Shraddha Patel, Reshma Pujara, Dipen V Patel, Mayur K Shinde, Somashekhar M Nimbalkar
{"title":"Newborn Vitals in the First 10 min Do Not Differ With Mode of Delivery.","authors":"Archana S Nimbalkar, Minal Patel, Krishna Mori, Shraddha Patel, Reshma Pujara, Dipen V Patel, Mayur K Shinde, Somashekhar M Nimbalkar","doi":"10.1155/ijpe/7764047","DOIUrl":"10.1155/ijpe/7764047","url":null,"abstract":"<p><p>We compared the physiological transition of neonates > 35 weeks old that are born vaginally versus those born by elective LSCS using SpO2, heart rate, and temperature in the first 10 min of life. We recorded the SpO2 of babies at 0, 15, 30, 45, 60, and 75 s until 5 min (15-s intervals) and every 30 s after that until 10 min. Heart rate was recorded using a stethoscope at 30-s intervals by counting for 6 s and multiplying by 10. The Temperature was recorded every 1-10 min via a digital thermometer. The study included 221 neonates, with 111 being born vaginally. Baseline characteristics such as gestational age, sex, and weight were comparable. The mean duration of skin-to-skin contact was higher in the vaginal deliveries as compared with LSCS (32.1 [8.6] vs. 4.6 [4], <i>p</i> < 0.001). The mean SpO2 in both groups at different time intervals was not statistically significant up to 6 min. It was higher in normal vaginal deliveries until 9 min (statistically significant). After 9 min, it was similar in both groups. Heart rate and temperature were similar in both groups. Physiological parameters in the newborn do not differ much despite the difference in delivery methods.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":"2026 ","pages":"7764047"},"PeriodicalIF":2.2,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13069433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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