儿童塑料性支气管炎:10 年间 55 例病例回顾

IF 1.3 Q3 PEDIATRICS
International Journal of Pediatrics Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI:10.1155/2024/9271324
Xiaowen Chen, Shangzhi Wu, Zhanhang Huang, Yuneng Lin, Jiaxing Xu, Qingyun Xu, Dehui Chen
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引用次数: 0

摘要

目的:总结整形性支气管炎(PB)患者的临床特征和治疗经验:总结塑性支气管炎(PB)患者的临床特征和治疗经验:回顾性研究2012年1月至2022年5月期间在一家医疗机构通过支气管镜切除树状结节确诊为塑性支气管炎的所有患者。从电子病历中检索人口统计学和临床数据:共有 55 例患者符合研究条件,中位年龄为 5.3 岁。19例患者患有基础疾病,其中以哮喘最为常见。入院前的病程中位数为 11 天。临床症状以咳嗽和发热为主,湿啰音(78.2%)和呼吸困难(61.8%)是最常见的体征。最常见的实验室检查结果是 C 反应蛋白升高(58.2%)。斑片状混浊是最常见的影像学表现(81.2%),其次是合并症(60.0%)和胸腔积液(43.6%)。在 41 例病例中检测到呼吸道病原体,其中最常见的是肺炎双球菌(41.8%),其次是腺病毒(20.0%)和乙型流感病毒(10.9%)。患者通过肺泡灌洗、氨溴索浸泡(63.6%)和镊子(30.9%)去除石膏。患者平均接受了 2.3 次支气管镜检查,首次检查的中位时间为入院后 3 天。所有患者都使用了抗生素,33 名患者(60.0%)使用了甲基强的松龙,25 名患者(45.5%)使用了丙种球蛋白。共有 53 例患者病情好转,总死亡率为 3.6%:儿童肺结核的特点是气道阻塞,主要由呼吸道感染引起,及时通过支气管镜取出石膏是最有效的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Plastic Bronchitis in Children: A Review of 55 Cases over a 10-Year Period.

Objective: To summarize the clinical characteristics and treatment experiences of patients with plastic bronchitis (PB).

Methods: All patients who were diagnosed with PB by bronchoscopic removal of tree-like casts at a single institution from January 2012 to May 2022 were retrospectively reviewed. Demographic and clinical data were retrieved from electronic patient records.

Results: A total of 55 patients, with a median age of 5.3 years, were eligible for the study. Nineteen cases had underlying diseases, among which asthma was the most common. The median course of the disease before admission was 11 days. Clinical symptoms were characterized by cough and fever, while moist rales (78.2%) and dyspnea (61.8%) were the most common signs. The most common laboratory finding was elevated C-reactive protein (58.2%). Patchy opacity was the most frequent radiographic finding (81.2%), followed by consolidation (60.0%) and pleural effusion (43.6%). Respiratory pathogens were detected in 41 cases, and M. pneumoniae was the most common one (41.8%), followed by adenovirus (20.0%) and influenza B virus (10.9%). The casts were removed by alveolar lavage, combined with ambroxol immersion (63.6%) and forceps (30.9%). Patients received an average of 2.3 bronchoscopies, and the median time for the first procedure was 3 days after admission. Antibiotics were given to all patients, methylprednisolone to 33 (60.0%), and gamma globulin to 25 (45.5%). A total of 53 cases were improved with an overall mortality rate of 3.6%.

Conclusions: PB in children is characterized by airway obstruction, mostly caused by respiratory infections, and timely removal of the cast by bronchoscopy is the most effective treatment.

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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
审稿时长
4 weeks
期刊介绍: International Journal of Pediatrics is a peer-reviewed, open access journal that publishes original researcharticles, review articles, and clinical studies in all areas of pediatric research. The journal accepts submissions presented as an original article, short communication, case report, review article, systematic review, or letter to the editor.
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