Microbial Pattern of Neonatal Sepsis in the Neonatal Intensive Care Unit of dr. Ramelan Navy Central Hospital.

IF 1.3 Q3 PEDIATRICS
International Journal of Pediatrics Pub Date : 2024-05-28 eCollection Date: 2024-01-01 DOI:10.1155/2024/6264980
Stefani Miranda, Aminuddin Harahap, Dominicus Husada, Fara Nayo Faramarisa
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引用次数: 0

Abstract

Background: The morbidity and mortality rates from neonatal sepsis remain high. However, there is limited information about the microbial pattern of neonatal sepsis in Indonesia. Microbial patterns can give an overview of the hygiene of an environment and act as a determinant for choosing definitive antibiotic treatment in neonatal sepsis patients. The organisms that cause neonatal sepsis differ from unit to unit and from time to time within the same unit.

Objectives: This study is aimed at discovering the microbial pattern of neonatal sepsis in the Neonatal Intensive Care Unit (NICU), dr. Ramelan Navy Central Hospital, in 2021-2022.

Methods: This is a retrospective, cross-sectional study that takes secondary data from the NICU and clinical microbiology department of dr. Ramelan Navy Central Hospital. Data that met the inclusion and exclusion criteria available between January 1, 2021, and December 31, 2022, were collected. Patients whose blood cultures were positive for bacterial growth and diagnosed with sepsis were selected as the study sample.

Results: Out of 174 samples, 93 (53.4%) were found positive for bacterial infection and diagnosed as neonatal sepsis. Gram-negative isolates (96.8%) were predominant. Sixty-point-two percent of Klebsiella pneumoniae XDR, 19.4% of Klebsiella pneumoniae ESBL, and 8.6% of Burkholderia cepacia XDR were identified. The gram-positive isolates found in this study were only 3 samples (3.2%). Two-point-one percent of MRSA and 1.1% of Staphylococcus haemolyticus MDR were identified.

Conclusion: The most common microorganisms causing neonatal sepsis in our NICU were gram-negative bacteria, particularly Klebsiella pneumoniae XDR. Following the recommended infection control procedures, practicing good hand hygiene, and having access to basic supplies and equipment are important to prevent and reduce the incidence of sepsis.

拉米兰海军中心医院新生儿重症监护室新生儿败血症的微生物模式。
背景:新生儿败血症的发病率和死亡率居高不下。然而,有关印度尼西亚新生儿败血症微生物模式的信息却很有限。微生物模式可以概括环境的卫生状况,也是新生儿败血症患者选择确定性抗生素治疗的决定因素。导致新生儿败血症的微生物在不同单位和同一单位不同时间段都有所不同:本研究旨在发现 2021-2022 年拉米兰海军中心医院新生儿重症监护室(NICU)新生儿败血症的微生物模式:这是一项回顾性横断面研究,从拉米兰海军中心医院新生儿重症监护室和临床微生物学部门获取二手数据。研究收集了 2021 年 1 月 1 日至 2022 年 12 月 31 日期间符合纳入和排除标准的数据。选取血液培养细菌生长呈阳性并被诊断为败血症的患者作为研究样本:在 174 份样本中,93 份(53.4%)发现细菌感染呈阳性,并被诊断为新生儿败血症。分离出的细菌以革兰氏阴性菌为主(96.8%)。其中有 62% 的肺炎克雷伯菌 XDR、19.4% 的肺炎克雷伯菌 ESBL 和 8.6% 的伯克霍尔德氏菌 XDR。本研究中发现的革兰氏阳性分离菌只有 3 个样本(3.2%)。2.1%的 MRSA 和 1.1%的溶血性葡萄球菌被鉴定为 MDR:结论:在我们的新生儿重症监护室中,导致新生儿败血症的最常见微生物是革兰氏阴性菌,尤其是肺炎克雷伯菌 XDR。遵循建议的感染控制程序、保持良好的手部卫生以及使用基本用品和设备对于预防和减少败血症的发生非常重要。
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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
审稿时长
4 weeks
期刊介绍: International Journal of Pediatrics is a peer-reviewed, open access journal that publishes original researcharticles, review articles, and clinical studies in all areas of pediatric research. The journal accepts submissions presented as an original article, short communication, case report, review article, systematic review, or letter to the editor.
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