Journal of Global Infectious Diseases最新文献

{"title":"Purple Urine Bag Syndrome in Urinary Tract Infection.","authors":"Yoseph Jappi,&nbsp;Usman Hadi","doi":"10.4103/jgid.jgid_144_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_144_22","url":null,"abstract":"<p><p>Purple urine bag syndrome (PUBS) is an unusual manifestation of urinary tract infection, characterized by purple discoloration of urine. Due to its rarity, it can be challenging for some physicians to manage it properly. In addition, its striking appearance can cause concern to some patients. This condition usually occurs in the debilitated geriatric population with prolonged use of an indwelling urinary catheter. However, our case highlights the development of PUBS in a young adult with a relatively short period of urinary catheterization.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/c3/JGID-15-84.PMC10353638.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9898915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristic Array of Imaging Markers in Central Nervous System Tuberculosis.","authors":"Shambaditya Das,&nbsp;Biman Kanti Ray,&nbsp;Alak Pandit,&nbsp;Keshaw Kumar,&nbsp;Souvik Dubey","doi":"10.4103/jgid.jgid_102_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_102_22","url":null,"abstract":"A 50-year-old female presented to us with a low-grade fever along with night sweats for a month. This was associated with holocranial headache and photophobia for the last 10 days and gradually worsening sensorium for the last 7 days. On admission, the patient was stuporous. Neurological examination was marked by neck stiffness, very sluggishly reacting bilateral dilated pupil, panhyporeflexia, and bilateral extensor plantar response.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/81/JGID-15-79.PMC10353641.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9898916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinico Virological Characterization of Hand, Foot and Mouth Disease in a Tertiary Care Hospital, South India.","authors":"Christi Rajaseker,&nbsp;P Ferdinamarie Sharmila,&nbsp;Malathi Munisamy,&nbsp;Vanathy Kandhasamy,&nbsp;Raja Sundaramurthy,&nbsp;Rahul Dhodapkar","doi":"10.4103/jgid.jgid_145_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_145_22","url":null,"abstract":"<p><strong>Introduction: </strong>Hand, foot, and mouth disease (HFMD) is a common childhood infectious disease, caused by enteroviruses (EVs) which can present with typical or atypical lesions. Although the disease is self-limiting, it can also lead to serious complications. In the era of polio eradication, it is important to understand the population dynamics of enteroviruses causing HFMD as one of the circulating strains may become dominant.</p><p><strong>Methods: </strong>It was a collaborative study carried out in the Department of Dermatology and Microbiology of a tertiary care teaching hospital. The throat swabs were collected from 132 suspected HFMD cases. Real-time polymerase chain reaction (PCR) was performed to detect the presence of pan enteroviruses, followed by genotype-specific PCR targeting Human Enterovirus 71 (HEV-71) and Coxsackie virus A16 (CVA-16) and CVA-6 for pan Enterovirus-positive samples. Follow-up samples were collected from 14 children in the 2^nd week and subjected to molecular testing to detect enteroviruses.</p><p><strong>Results: </strong>Among 132 children suspected to have HFMD, 44 were girls and 88 were boys, and the majority of them 76.5% (101/132) were under 2 years of age. A history of exposure to a similar clinical presentation was present in 15 children. Of 132 suspected cases, 60 samples (45.5%) were positive for pan Enterovirus. The predominantly circulating genotype was found to be CVA-6 (31.6% [19/60]). There were about 10 cases (16.6%) which had co-infection with both HEV71 and CVA-6. Rash with fever was the most common presentation (57%). In most of the cases with HEV 71, 92.3% (12/13) presented within 3 days of illness to the health-care facility. Of 60 positive cases, 25% (15/60) of children had the atypical distribution of rashes in the face, trunk, genitalia, thigh, neck, and axilla and 16.7% of children (10/60) had the atypical type of lesion either only papular lesions or erythema multiforme. Out of 14 follow-up samples, 13 were negative for EVs; one was positive for pan EV in the 2^nd week, however, the patient lost to follow-up after that.</p><p><strong>Conclusion: </strong>HFMD outbreaks in our region were caused by various genotypes of enteroviruses. No severe complications were seen in the affected children. Nearly 30% had atypical presentation either in the form of lesion or site. Robust molecular epidemiological surveillance of HFMD is required to know the strain variations and other emerging genotypes in our setup.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/89/JGID-15-13.PMC10118210.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proven Impact of an Advanced Air Purification System in the Reduction of Infectious Airborne and Surface Pathogens, Concomitant Reduction of Hospital-acquired Infections and Length of Stay, and Improvement in Health-care Economics.","authors":"Stanislaw P Stawicki,&nbsp;Alicia Raquel Urrutia,&nbsp;Charles N Kimble,&nbsp;Kathryn Colonna Worrilow","doi":"10.4103/jgid.jgid_11_23","DOIUrl":"https://doi.org/10.4103/jgid.jgid_11_23","url":null,"abstract":"Annually, approximately one out of every 20 inpatients or an estimated 1.7 million individuals experience a hospital-acquired infection (HAI) in the US. In practice, this means that 5%–10% of admitted patients will develop an HAI and approximately 100,000 of these patients will die.[1,2] The estimated incidence of HAIs exceeds that of many other reportable diseases in the US, and the number of HAI-related deaths is greater than many of the leading causes of mortality.[1]","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/70/JGID-15-3.PMC10118215.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"State of the Globe: Aerosol Boxes in Intensive Care - A Boon or a Myth.","authors":"Kartik Syal,&nbsp;Ankita Chandel","doi":"10.4103/jgid.jgid_32_23","DOIUrl":"https://doi.org/10.4103/jgid.jgid_32_23","url":null,"abstract":"The very data suggests that this particular variant was not only highly contagious, spreading like wildfire but was also virulent enough to cause such a degree of catastrophe to the entire human race. The case fatality ratio varied as the disease progressed (being >20% at outset in Wuhan to almost <5% after a year in Wuhan, attributable to better understanding of the disease and improved care).[3] Furthermore, the overall case fatality ratio varied with different countries (ranging from 2% to 10%).[4] Thus, with such transmissibility and significantly high case fatality rate, the disease forced the authorities and the health-care systems all over the world to put forward plans to curb the spread and lessen the mortality in a hurry. Health-care workers were the frontline warriors and a WHO estimate showed that 80,000–180,000 health-care workers died because of the disease between January 2020 and May 2021.[5]","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/a6/JGID-15-1.PMC10118206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Erysipelothrix</i> Bacteremia; is Endocarditis a Rule?","authors":"Haripriya Reddy Challa,&nbsp;Ashwini Choudary Tayade,&nbsp;Srimathy Venkatesh,&nbsp;P Senthur Nambi","doi":"10.4103/jgid.jgid_30_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_30_22","url":null,"abstract":"<p><p><i>Erysipelothrix rhusiopathiae</i> is a Gram-positive bacillus, a zoonotic pathogen rarely causing human infections ranging from localized skin infections to invasive infections such as endocarditis. In this report, we present two cases of <i>Erysipelothrix</i> bacteremia. The first case is a native valve tricuspid endocarditis, which is a highly unusual valve to be involved. The second case is bacteremia, probably secondary to a minor skin breach, which did not involve heart valves. <i>Erysipelothrix</i> bacteremia is considered highly associated with infective endocarditis and a high mortality rate, which could be a bias due to underreporting of <i>Erysipelothrix</i> bacteremia without endocarditis. <i>Erysipelothrix</i> is intrinsically resistant to vancomycin, the first-line agent for Gram-positive bacteremia. Both the patients in this report were treated successfully with ceftriaxone.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/9b/JGID-15-31.PMC10118208.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9444330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studded Brainstem Tuberculoma Presenting with Bilateral Inter-Nuclear Ophthalmoplegia.","authors":"Rajesh Verma,&nbsp;Rajarshi Chakraborty","doi":"10.4103/jgid.jgid_203_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_203_22","url":null,"abstract":"","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/e7/JGID-15-38.PMC10118209.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 and Legionella Co-Infection.","authors":"Caitlin A Gauvin,&nbsp;Barbara Mian,&nbsp;George Psevdos,&nbsp;Audun J Lier","doi":"10.4103/jgid.jgid_92_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_92_22","url":null,"abstract":"The COVID-19 pandemic has caused a historic public health emergency, with an estimated 458 million confirmed cases and 6 million deaths.[1] The highly transmissible SARS-CoV-2 virus can cause severe pneumonia as well as extrapulmonary sequelae, making accurate diagnosis and management crucial.[2] Legionnaire’s disease is a severe atypical bacterial pneumonia that can be associated with SARS-CoV-2 infection.[3] Like SARS-CoV-2 infection, legionella may be associated with extrapulmonary symptoms, including diarrhea, hyponatremia, and neurological manifestations such as encephalopathy, among others.[4] Importantly, the mortality rate of legionella infection is high, with one study reporting over 6% mortality despite appropriate antibiotic therapy with either azithromycin or a fluoroquinolone.[5]","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cf/2e/JGID-15-40.PMC10118213.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruptured Pulmonary Hydatid Cyst.","authors":"Ananda Datta,&nbsp;Srikanth M Goud,&nbsp;Prasanta Raghab Mohapatra","doi":"10.4103/jgid.jgid_137_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_137_22","url":null,"abstract":"<p><p>A 37-year-old male presented with left-sided hydropneumothorax. After drainage of fluid and air from the pleural cavity, chest radiograph and computed tomography of chest showed characteristic radiological image of ruptured hydatid cyst. The diagnosis was supported by positive echinococcal serology.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/4c/JGID-15-35.PMC10118214.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waning of Antibody Response Among Vaccinees who Received Two Doses of Covishield Vaccine.","authors":"Shivani Haritay,&nbsp;Rithia Patil,&nbsp;Arif Maldar,&nbsp;Anil Kumar,&nbsp;Vikrama Reddy,&nbsp;Deshna Oswal,&nbsp;Masood Ahmed Tahashildar,&nbsp;Akshay Kolakar,&nbsp;Satish Kabbur,&nbsp;Jang Bahadur Prasad,&nbsp;M S Shivaswamy,&nbsp;Ramesh Paranjape,&nbsp;Mubashir Angolkar","doi":"10.4103/jgid.jgid_128_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_128_22","url":null,"abstract":"<p><strong>Introduction: </strong>There are limited data available on the long-term presence of SARS-CoV-2-specific binding antibodies and neutralizing antibodies in circulation among the elderly population. This study aims to examine levels of anti-SARS-CoV-2 antibodies in vaccines who have completed at least 6 months since the second vaccine dose. A cross-sectional study was conducted from November 2021 to January 2022 among 199 vaccines aged 60 years and above residing in Belagavi city, who received two doses of the Covishield vaccine.</p><p><strong>Methods: </strong>Antibody response to SARS-COV-2 virus whole cell antigen was measured by a kit COVID KAWACH IgG Micro LISA (J Mitra and Company, India) in 199 participants who had completed at least 6 months after receiving the second dose of Covishield vaccine. The antibody response was measured as a ratio of optical density (OD) in the participant's sample to the mean OD in negative control test by normal (T/N). Independent Kruskal-Wallis test was applied to test the difference between the T/N ratio by months of vaccination since the second dose and by the age group strata.</p><p><strong>Results: </strong>The median T/N values among participants who completed 6, 7, 8, and 9 months since the second vaccine dose were 14.17, 10.46, 7.93, and 5.11, respectively, and this decline in T/N values was statistically significant. Antibody response values showed a decline with increasing age for participants in the age strata 60-69, 70-79, and 80 and above, respectively.</p><p><strong>Conclusions: </strong>A significant decline was observed in antibody response over 9 months supporting the administration of booster dose of vaccine.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/89/JGID-15-19.PMC10118211.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}