{"title":"Pancolitis in Enteric Fever: A Rare Occurrence.","authors":"Prabhat Kumar, Manish Kumar","doi":"10.4103/jgid.jgid_229_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_229_22","url":null,"abstract":"Enteric fever is a common bacterial illness caused by ingesting contaminated food and water in developing countries. It includes typhoid fever, caused by Salmonella typhi and parathyroid fever, caused by Salmonella Paratyphi A and B. Paratyphoid fever is uncommon and relatively milder compared to typhoid fever. Gastrointestinal involvement is frequent in enteric fever; commonly involved sites are the terminal ileum, ileocecal valves, and ascending and transverse colon, respectively. Involvement of descending colon is rare. Herein, we present a rare case of pancolitis in paratyphoid fever.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 2","pages":"86-87"},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/7b/JGID-15-86.PMC10353637.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9847680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Very Rare Combination of Hantavirus Cardiopulmonary Syndrome and Hanta Hemorrhagic Fever with Renal Syndrome.","authors":"Sudha Prasanth Reddy, Kunal Kumar Narang, Suraj Rajendra Patil","doi":"10.4103/jgid.jgid_235_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_235_22","url":null,"abstract":"","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 2","pages":"88-89"},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/52/JGID-15-88.PMC10353645.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9898909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Tuberculosis Presenting as Diffuse Alveolar Hemorrhage.","authors":"Shridhar Pattar, Mayank Agarwal, Bishal Shah, Monika Pathania","doi":"10.4103/jgid.jgid_13_23","DOIUrl":"https://doi.org/10.4103/jgid.jgid_13_23","url":null,"abstract":"Hemoptysis is a common presentation of pulmonary tuberculosis; however, diffuse alveolar hemorrhage (DAH) is a rare association. DAH is a life-threatening medical condition which presents with hemoptysis, anemia, diffuse radiographic pulmonary infiltrates, and acute respiratory distress.[1] It is usually associated with autoimmune diseases such as systemic vasculitides, systemic lupus erythematosus, anti-glomerular basement membrane (GBM) disease, certain malignancies, and infections.[2,3] Cytomegalovirus, adenovirus, invasive aspergillosis, mycoplasma, influenza, and even staphylococcus infection have been associated with DAH.[3] However, pulmonary tuberculosis causing DAH has rarely been reported in the literature.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 2","pages":"90-91"},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/04/JGID-15-90.PMC10353640.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9842402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Central Retinal Artery Occlusion in COVID-Associated Mucormycosis.","authors":"Smiti Rani Srivastava, Peyalee Sarkar, Purban Ganguly, Debaleena Mukherjee, Biman Kanti Ray, Souvik Dubey, Alak Pandit, Amitabh Sengupta, Manimoy Bandopadhyay, Asim Kumar Ghosh, Kanika Gupta Poddar, Soumyajit Guha, Asif Ayub","doi":"10.4103/jgid.jgid_185_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_185_22","url":null,"abstract":"<p><strong>Introduction: </strong>Significant surge of mucormycosis was reported in the Indian Subcontinent during the second wave of the COVID-19 pandemic. COVID-associated mucormycosis (CAM) was defined as the development of features of mucormycosis with prior or current history of COVID-19 infection. Rapid angioinvasion is an important characteristic of mucormycosis. Authors intended to find out the prevalence of retinal arterial occlusion and its association with vascular embolic occlusion elsewhere in the body among CAM patients in this study.</p><p><strong>Methods: </strong>This was an observational study. All consecutive-confirmed cases of mucormycosis (<i>n</i> = 89) and age-/gender-/risk factor-matched controls (<i>n</i> = 324) admitted in the designated COVID center were included in the study. All cases and controls underwent comprehensive ophthalmological, otorhinological, and neurological examinations. All necessary investigations to support the clinical diagnosis were done. Qualitative data were analyzed using the Chi-square test. Quantitative data for comparison of means between the cases and controls were done using unpaired <i>t</i>-test.</p><p><strong>Results: </strong>Twenty-one (23.59%) patients manifested the defined outcome of central retinal artery occlusion (CRAO). Among age-matched control, with similar diabetic status, none had developed the final outcome as defined (<i>P</i> < 0.05). About 90.47% of subjects with CRAO presented with no perception of light vision. Thirteen subjects (61.9%) with the final outcome developed clinical manifestations of stroke during the course of their illness with radiological evidence of watershed infarction (<i>P</i> = 0.001). Orbital debridement was performed in 9 (42.85%) subjects while orbital exenteration was done in 8 (38.09%) subjects.</p><p><strong>Conclusions: </strong>CRAO in CAM patients was found to have aggressive nature turning the eye blind in a very short period of time. CRAO can serve as a harbinger for subsequent development of more debilitating and life-threatening conditions such as stroke among CAM patients.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 2","pages":"66-71"},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/6d/JGID-15-66.PMC10353642.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9847681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Purple Urine Bag Syndrome in Urinary Tract Infection.","authors":"Yoseph Jappi, Usman Hadi","doi":"10.4103/jgid.jgid_144_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_144_22","url":null,"abstract":"<p><p>Purple urine bag syndrome (PUBS) is an unusual manifestation of urinary tract infection, characterized by purple discoloration of urine. Due to its rarity, it can be challenging for some physicians to manage it properly. In addition, its striking appearance can cause concern to some patients. This condition usually occurs in the debilitated geriatric population with prolonged use of an indwelling urinary catheter. However, our case highlights the development of PUBS in a young adult with a relatively short period of urinary catheterization.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 2","pages":"84-85"},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/c3/JGID-15-84.PMC10353638.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9898915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characteristic Array of Imaging Markers in Central Nervous System Tuberculosis.","authors":"Shambaditya Das, Biman Kanti Ray, Alak Pandit, Keshaw Kumar, Souvik Dubey","doi":"10.4103/jgid.jgid_102_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_102_22","url":null,"abstract":"A 50-year-old female presented to us with a low-grade fever along with night sweats for a month. This was associated with holocranial headache and photophobia for the last 10 days and gradually worsening sensorium for the last 7 days. On admission, the patient was stuporous. Neurological examination was marked by neck stiffness, very sluggishly reacting bilateral dilated pupil, panhyporeflexia, and bilateral extensor plantar response.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 2","pages":"79-80"},"PeriodicalIF":1.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/81/JGID-15-79.PMC10353641.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9898916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christi Rajaseker, P Ferdinamarie Sharmila, Malathi Munisamy, Vanathy Kandhasamy, Raja Sundaramurthy, Rahul Dhodapkar
{"title":"Clinico Virological Characterization of Hand, Foot and Mouth Disease in a Tertiary Care Hospital, South India.","authors":"Christi Rajaseker, P Ferdinamarie Sharmila, Malathi Munisamy, Vanathy Kandhasamy, Raja Sundaramurthy, Rahul Dhodapkar","doi":"10.4103/jgid.jgid_145_22","DOIUrl":"https://doi.org/10.4103/jgid.jgid_145_22","url":null,"abstract":"<p><strong>Introduction: </strong>Hand, foot, and mouth disease (HFMD) is a common childhood infectious disease, caused by enteroviruses (EVs) which can present with typical or atypical lesions. Although the disease is self-limiting, it can also lead to serious complications. In the era of polio eradication, it is important to understand the population dynamics of enteroviruses causing HFMD as one of the circulating strains may become dominant.</p><p><strong>Methods: </strong>It was a collaborative study carried out in the Department of Dermatology and Microbiology of a tertiary care teaching hospital. The throat swabs were collected from 132 suspected HFMD cases. Real-time polymerase chain reaction (PCR) was performed to detect the presence of pan enteroviruses, followed by genotype-specific PCR targeting Human Enterovirus 71 (HEV-71) and Coxsackie virus A16 (CVA-16) and CVA-6 for pan Enterovirus-positive samples. Follow-up samples were collected from 14 children in the 2<sup>nd</sup> week and subjected to molecular testing to detect enteroviruses.</p><p><strong>Results: </strong>Among 132 children suspected to have HFMD, 44 were girls and 88 were boys, and the majority of them 76.5% (101/132) were under 2 years of age. A history of exposure to a similar clinical presentation was present in 15 children. Of 132 suspected cases, 60 samples (45.5%) were positive for pan Enterovirus. The predominantly circulating genotype was found to be CVA-6 (31.6% [19/60]). There were about 10 cases (16.6%) which had co-infection with both HEV71 and CVA-6. Rash with fever was the most common presentation (57%). In most of the cases with HEV 71, 92.3% (12/13) presented within 3 days of illness to the health-care facility. Of 60 positive cases, 25% (15/60) of children had the atypical distribution of rashes in the face, trunk, genitalia, thigh, neck, and axilla and 16.7% of children (10/60) had the atypical type of lesion either only papular lesions or erythema multiforme. Out of 14 follow-up samples, 13 were negative for EVs; one was positive for pan EV in the 2<sup>nd</sup> week, however, the patient lost to follow-up after that.</p><p><strong>Conclusion: </strong>HFMD outbreaks in our region were caused by various genotypes of enteroviruses. No severe complications were seen in the affected children. Nearly 30% had atypical presentation either in the form of lesion or site. Robust molecular epidemiological surveillance of HFMD is required to know the strain variations and other emerging genotypes in our setup.</p>","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 1","pages":"13-18"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/89/JGID-15-13.PMC10118210.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stanislaw P Stawicki, Alicia Raquel Urrutia, Charles N Kimble, Kathryn Colonna Worrilow
{"title":"Proven Impact of an Advanced Air Purification System in the Reduction of Infectious Airborne and Surface Pathogens, Concomitant Reduction of Hospital-acquired Infections and Length of Stay, and Improvement in Health-care Economics.","authors":"Stanislaw P Stawicki, Alicia Raquel Urrutia, Charles N Kimble, Kathryn Colonna Worrilow","doi":"10.4103/jgid.jgid_11_23","DOIUrl":"https://doi.org/10.4103/jgid.jgid_11_23","url":null,"abstract":"Annually, approximately one out of every 20 inpatients or an estimated 1.7 million individuals experience a hospital-acquired infection (HAI) in the US. In practice, this means that 5%–10% of admitted patients will develop an HAI and approximately 100,000 of these patients will die.[1,2] The estimated incidence of HAIs exceeds that of many other reportable diseases in the US, and the number of HAI-related deaths is greater than many of the leading causes of mortality.[1]","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 1","pages":"3-5"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/70/JGID-15-3.PMC10118215.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"State of the Globe: Aerosol Boxes in Intensive Care - A Boon or a Myth.","authors":"Kartik Syal, Ankita Chandel","doi":"10.4103/jgid.jgid_32_23","DOIUrl":"https://doi.org/10.4103/jgid.jgid_32_23","url":null,"abstract":"The very data suggests that this particular variant was not only highly contagious, spreading like wildfire but was also virulent enough to cause such a degree of catastrophe to the entire human race. The case fatality ratio varied as the disease progressed (being >20% at outset in Wuhan to almost <5% after a year in Wuhan, attributable to better understanding of the disease and improved care).[3] Furthermore, the overall case fatality ratio varied with different countries (ranging from 2% to 10%).[4] Thus, with such transmissibility and significantly high case fatality rate, the disease forced the authorities and the health-care systems all over the world to put forward plans to curb the spread and lessen the mortality in a hurry. Health-care workers were the frontline warriors and a WHO estimate showed that 80,000–180,000 health-care workers died because of the disease between January 2020 and May 2021.[5]","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"15 1","pages":"1-2"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/a6/JGID-15-1.PMC10118206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}