Respiratory Medicine Case Reports最新文献_第8页

Pulmonary arteriovenous malformation diagnosed by recurrent hemothorax – A case report 复发性血胸诊断肺动脉动静脉畸形1例

IF 0.8

Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102204

Toshiki Sakuma , Hajime Kasai , Toshihiko Sugiura , Kenichiro Takeda , Minori Watanabe , Kenichi Suzuki , Takashi Urushibara , Takuji Suzuki

{"title":"Pulmonary arteriovenous malformation diagnosed by recurrent hemothorax – A case report","authors":"Toshiki Sakuma , Hajime Kasai , Toshihiko Sugiura , Kenichiro Takeda , Minori Watanabe , Kenichi Suzuki , Takashi Urushibara , Takuji Suzuki","doi":"10.1016/j.rmcr.2025.102204","DOIUrl":"10.1016/j.rmcr.2025.102204","url":null,"abstract":"<div><h3>Background</h3><div>A pulmonary arteriovenous malformation (PAVM) is an abnormal connection between a pulmonary artery and vein that causes various complications owing to a right-to-left shunt. However, hemorrhagic complications developing from a PAVM are rare.</div></div><div><h3>Case report</h3><div>We report the case of a 61-year-old woman with a PAVM complicated by hemothorax. She had a history of right hemothorax with no identifiable cause during pregnancy 35 years prior to presentation. Although the PAVM had been identified on chest computed tomography two months previously, the patient was observed. She visited a nearby hospital with back pain and dyspnea without any inciting factor nor history of trauma. Contrast-enhanced chest CT showed a PAVM in the posterior segment of the right upper lobe and another in the apical-posterior segment of the left upper lobe. Detailed examinations suggested both past and present hemothorax due to rupture of the PAVM close to the pleura of the right upper lobe. As there was no progression of the presumed hemothorax during the index hospitalization, the patient was managed conservatively. After the hemothorax resolved, the patient underwent elective coil embolization at our facility. No recurrence of hemothorax was observed over a 10-month follow-up period.</div></div><div><h3>Conclusion</h3><div>A PAVM can cause recurrent hemothorax, and should be considered when evaluating a patient with hemothorax. If the cause of the hemothorax cannot be identified, a PAVM may become apparent after a long period of time.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"55 ","pages":"Article 102204"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EGFR-mutant lung adenocarcinoma transformed into small cell Lung cancer: A case report and literatures review egfr突变型肺腺癌转化为小细胞肺癌1例报告并文献复习

IF 0.8

Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102219

Jinhong Chen , Hongxiang Huang , Peiyuan Zhong , Sujuan Peng , Xie Zhu , Xinjing Ding , Fen Wang , Ping Kong , Tiantian Song , Zhihui Lu , Li Chen

{"title":"EGFR-mutant lung adenocarcinoma transformed into small cell Lung cancer: A case report and literatures review","authors":"Jinhong Chen , Hongxiang Huang , Peiyuan Zhong , Sujuan Peng , Xie Zhu , Xinjing Ding , Fen Wang , Ping Kong , Tiantian Song , Zhihui Lu , Li Chen","doi":"10.1016/j.rmcr.2025.102219","DOIUrl":"10.1016/j.rmcr.2025.102219","url":null,"abstract":"<div><div>Advances in molecular biology have positioned epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) as highly effective therapies for patients with EGFR-mutant carcinomas. However, the inevitable emergence of acquired resistance significantly limits their long-term efficacy. Among resistance mechanisms, the transformation of lung adenocarcinoma to small cell lung cancer (SCLC) following EGFR-TKIs therapy is an uncommon but clinically important phenomenon contributing to treatment failure.</div><div>We present a case of SCLC transformation in a patient with EGFR-mutant lung adenocarcinoma after 8 months of first-line osimertinib therapy. Following 4 cycles of etoposide combined with lobaplatin chemotherapy, adenocarcinoma cells regained predominance, illustrating a dynamic histological shift between adenocarcinoma and SCLC phenotypes. Subsequent treatment with 2 cycles of chemotherapy plus osimertinib resulted in disease stabilization. However, multiple brain metastases were identified 3 months after completing 6 cycles of chemotherapy.</div><div>This case underscores the bidirectional histological plasticity between lung adenocarcinoma and SCLC during treatment and highlights the critical importance of repeated biopsies for guiding management strategies in the context of resistance. We also provide a comprehensive review of the clinical manifestations, underlying mechanisms, predictive biomarkers, and therapeutic approaches for SCLC transformation.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"55 ","pages":"Article 102219"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Lethal Case of Acute Exacerbation of Rheumatoid Arthritis – Related Interstitial Lung Disease Induced by the COVID Vaccine. 类风湿性关节炎急性加重的致命病例--COVID 疫苗诱发的相关间质性肺病

IF 1.1

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2023.101959

Rayan Mohamad, Rami Hallak, Imad Bou Akl, Hisham Bou Fakhreddine

引用次数: 0

Varicella pneumonia in an immunocompetent adult patient: Case report and review of the literature 免疫功能正常的成年患者患上水痘肺炎：病例报告和文献综述

IF 0.8

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102112

Carlos Felipe Arias-Osorio , Heiler Lozada-Ramos , Jorge Enrique Daza-Arana , Luis Miguel Osorio-Toro , Diana Marcela Bonilla-Bonilla

{"title":"Varicella pneumonia in an immunocompetent adult patient: Case report and review of the literature","authors":"Carlos Felipe Arias-Osorio , Heiler Lozada-Ramos , Jorge Enrique Daza-Arana , Luis Miguel Osorio-Toro , Diana Marcela Bonilla-Bonilla","doi":"10.1016/j.rmcr.2024.102112","DOIUrl":"10.1016/j.rmcr.2024.102112","url":null,"abstract":"<div><div>Varicella is a childhood disease characterized by its self-limiting and benign nature. However, it can also affect the adult population due to risk factors, leading to infection with numerous complications involving the central nervous system, kidneys, respiratory system, and skin. Varicella pneumonia, one of the most feared complications in adults, occurs in approximately 1 out of 400 patients with the disease. This complication primarily affects male patients with a history of heavy smoking and immunosuppression, either due to an underlying disease such as HIV and cancer, drug use, pregnancy or pulmonary disease. It is recommended that this complication should be treated with intravenous acyclovir at a dose of 10 mg/kg/8 hours. The prognosis depends on the development of respiratory failure; up to 50 % of patients with this complication require invasive mechanical ventilation. Here, we report the clinical case of an immunocompetent patient with a typical presentation of varicella that rapidly progressed to a respiratory infection requiring antiviral treatment and invasive mechanical ventilation.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"52 ","pages":"Article 102112"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of intractable bronchopleural fistula with a one-side-closed silicone stent using retrograde approach: A case report 用逆行法单侧封闭硅胶支架治疗难治性支气管胸膜瘘：病例报告

IF 0.8

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102134

Masaya Tamura, Naoki Furukawa, Marino Yamamoto, Ryohei Miyazaki, Hironobu Okada

{"title":"Treatment of intractable bronchopleural fistula with a one-side-closed silicone stent using retrograde approach: A case report","authors":"Masaya Tamura, Naoki Furukawa, Marino Yamamoto, Ryohei Miyazaki, Hironobu Okada","doi":"10.1016/j.rmcr.2024.102134","DOIUrl":"10.1016/j.rmcr.2024.102134","url":null,"abstract":"<div><div>A male patient (age: 85 -years) with lung cancer underwent basal segmentectomy. Subsequently, he underwent emergency open window thoracotomy for a bronchial stump fistula. The general and nutritional conditions of the patient improved; nevertheless, natural closure of the fistula did not occur. Therefore, the patient underwent fistula closure using an endobronchial Watanabe spigot, polyglycolic acid sheet and N-butyl-2-cyanoacrylate. Nine months later, the fistula had enlarged. The air leak was treated by applying pressure with gauze; however, this approach was not sufficiently effective, and the patient became unable to expectorate phlegm or speak. One side of a straight-type silicone stent with an outer diameter measuring 9mm was closed, and the stent was inserted into the fistula through the fenestration with the closed side at the tip. The L-sized endobronchial Watanabe spigot was placed into the lumen of the stent to reinforce it. Air leak from the fistula was significantly reduced, making breathing and expectoration easier. Retrograde closure of a bronchial fistula using a unilaterally closed silicon stent can be an effective treatment for large, refractory bronchial fistulas.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"52 ","pages":"Article 102134"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142537529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary interstitial glycogenosis in two neonates: Early recognition and use of corticosteroids 两名新生儿的肺间质糖原病：早期识别和使用皮质类固醇

IF 1.1

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.101990

Eric Hamberger , Yolanda Yu , Hyo-Jung Choi

引用次数: 0

Xanthogranulomatous pleuritis induced by recurrent biliothorax due to a biliopleural fistula: The first case report in the literature 胆管瘘导致的复发性胆气胸诱发黄疽性胸膜炎：文献中的首个病例报告

IF 1.1

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102065

Moatasem Hussein Al-janabi , Hussein Kaada , Ghina Ismail , Dommar Roumieh , Zuheir Al-Shehabi

{"title":"Xanthogranulomatous pleuritis induced by recurrent biliothorax due to a biliopleural fistula: The first case report in the literature","authors":"Moatasem Hussein Al-janabi , Hussein Kaada , Ghina Ismail , Dommar Roumieh , Zuheir Al-Shehabi","doi":"10.1016/j.rmcr.2024.102065","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102065","url":null,"abstract":"<div><p>Xanthogranulomatous pleuritis is an extremely rare pathological entity, characterized by the infiltration of foamy cells and multinucleated giant cells within the pleural space. This condition often mimics infectious and neoplastic processes, presenting significant diagnostic challenges. This report details the first documented case of xanthogranulomatous pleuritis induced by recurrent biliothorax due to a biliopleural fistula, presenting a unique clinical scenario. We describe the clinical presentation, diagnostic hurdles, and both the surgical and medical management of this case. The discovery of biliothorax, evidenced by pleural fluid bilirubin levels that exceed serum bilirubin levels, underscores the importance of considering biliothorax in the differential diagnosis of recurrent pleural effusions, particularly in patients with a history of trauma. This case emphasizes the need for heightened awareness and a multidisciplinary approach in the diagnosis and treatment to effectively manage this complex condition and prevent recurrence.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"50 ","pages":"Article 102065"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000881/pdfft?md5=360bfb07ca3bd5d990d0df0e8ad11ee5&pid=1-s2.0-S2213007124000881-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141294845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined allergic bronchopulmonary mycosis and eosinophilic granulomatosis with polyangiitis: A case report and literature review 过敏性支气管肺霉菌病和嗜酸性粒细胞肉芽肿伴多血管炎合并症：病例报告和文献综述

IF 1.1

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102012

Ning Cui, Jingluan Wang, Yanmei Shao, Jingming Zhao, Zhaozhong Cheng

引用次数: 0

Barking up the wrong tree: Vascular tree-in-bud due to intravascular lymphoma 误入歧途血管内淋巴瘤引起的血管树瘤

IF 1.1

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102020

Ravi Manglani , Ji-Hae Shin , Venkata Sireesha Chemarthi , Mohamad Raji , Anna Rozenshtein , Oleg Epelbaum

{"title":"Barking up the wrong tree: Vascular tree-in-bud due to intravascular lymphoma","authors":"Ravi Manglani , Ji-Hae Shin , Venkata Sireesha Chemarthi , Mohamad Raji , Anna Rozenshtein , Oleg Epelbaum","doi":"10.1016/j.rmcr.2024.102020","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102020","url":null,"abstract":"<div><p>A 59-year-old previously healthy woman presented with a six-month history of fever, nonproductive cough, and weight loss. The cause of these symptoms remained obscure despite a thorough, month-long hospitalization. On presentation, she was normotensive with a pulse of 98 beats/minute, respiratory rate of 20 breaths/minute, and a temperature of 39.4C. She was emaciated. Physical examination was notable for faint bibasilar crackles on lung auscultation. Initial laboratory testing revealed pancytopenia. Peripheral smear demonstrated normocytic, normochromic anemia without immature cells or schistocytes. Other notable laboratory findings included elevated levels of lactate dehydrogenase, elevated ferritin, and elevated levels of fasting serum triglycerides. A comprehensive laboratory evaluation for connective tissue disease was negative. Plain chest radiography was normal while computed tomography (CT) of the chest demonstrated sub-centimeter nodules in a branching centrilobular pattern as well as in a peri-lymphatic distribution without associated lymphadenopathy or organomegaly.</p><p>The above constellation of laboratory abnormalities raised concern for hemophagocytic lymphohistiocytosis (HLH). Soluble IL-2 (CD25) receptor levels were markedly elevated. Bronchoscopy with transbronchial biopsies of the right lower lobe was performed, revealing intravascular lymphoma associated with HLH. Our case emphasizes the need for clinicians to consider vascular causes of tree - in-bud nodules in addition to the conventional bronchiolar causes. The case also is a reminder of the need to conduct an exhaustive search for malignancy, in patients with HLH.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"49 ","pages":"Article 102020"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000431/pdfft?md5=40399c3fca7ea488c175d8a671e7e605&pid=1-s2.0-S2213007124000431-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140605564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report of a lung transplant recipient receiving belatacept in combination with low dose tacrolimus complicated by progressive multifocal leukoencephalopathy 接受贝拉替塞联合小剂量他克莫司治疗的肺移植受者并发进行性多灶性白质脑病的病例报告

IF 1.1

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102028

Vahdatpour C , Saha B , Younis M , Montuoro C , Timofte I , Rackauskas M , Emtiazjoo A

引用次数: 0