{"title":"Pulmonary alveolar proteinosis following severe COVID - 19 infection: A case report","authors":"Samina Martin, Shivu Kaushik, B. Bajantri","doi":"10.2139/ssrn.4685256","DOIUrl":"https://doi.org/10.2139/ssrn.4685256","url":null,"abstract":"","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ning Cui, Jingluan Wang, Yanmei Shao, Jingming Zhao, Zhaozhong Cheng
{"title":"Combined allergic bronchopulmonary mycosis and eosinophilic granulomatosis with polyangiitis: A case report and literature review","authors":"Ning Cui, Jingluan Wang, Yanmei Shao, Jingming Zhao, Zhaozhong Cheng","doi":"10.1016/j.rmcr.2024.102012","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102012","url":null,"abstract":"<div><p>A 27-year-old female visited our hospital with a history of asthma, peripheral blood eosinophilia, increased total IgE, Aspergillus fumigatus specific IgE, reversible mild bronchiectasis, sinusitis, bronchial mucus plugs and cultivation of Aspergillus from BALF. Glucocorticoids therapy is effective. These results met the diagnostic criteria for both allergic bronchopulmonary aspergillosis (ABPM) and eosinophilic granulomatosis with polyangiitis (EGPA). Special attention should be paid to the possibility of both diseases coexisting in the disease process.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000352/pdfft?md5=7055953510f9afe5cb8ef7d7df3a9401&pid=1-s2.0-S2213007124000352-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary interstitial glycogenosis in two neonates: Early recognition and use of corticosteroids","authors":"Eric Hamberger , Yolanda Yu , Hyo-Jung Choi","doi":"10.1016/j.rmcr.2024.101990","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.101990","url":null,"abstract":"<div><p>Pulmonary interstitial glycogenosis (PIG) is known to be associated with a wide variety of congenital conditions, though the extent to which PIG contributes to clinical presentation and outcomes in infants remains controversial. We describe two cases of infants with congenital anomalies and respiratory distress at birth who were diagnosed with PIG with differing clinical courses and response to methylprednisolone therapy. These cases highlight the importance of improved recognition of PIG and uncertainties about which patients may benefit from treatment.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000133/pdfft?md5=122c84234955f0af4d875cd0d08a6067&pid=1-s2.0-S2213007124000133-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139675755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Lethal Case of Acute Exacerbation of Rheumatoid Arthritis – Related Interstitial Lung Disease Induced by the COVID Vaccine.","authors":"Rayan Mohamad, Rami Hallak, Imad Bou Akl, Hisham Bou Fakhreddine","doi":"10.1016/j.rmcr.2023.101959","DOIUrl":"10.1016/j.rmcr.2023.101959","url":null,"abstract":"<div><p>Interstitial lung disease (ILD) exacerbation is a serious condition that can have a high morbidity and mortality. Identifying the triggers of ILD exacerbations is very challenging. Several case reports described COVID-19 vaccine-induced exacerbation of underlying interstitial lung disease, namely idiopathic interstitial pneumonias. The clinical implications of this adverse effect is underrecognized. We are reporting a case of fatal respiratory failure in a patient with rheumatoid arthritis Interstitial Lung disease few days following the second dose of COVID vaccine. Identifying risk factors of this complication is of utmost importance to aid in the rapid recognition and early initiation of treatment.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007123001545/pdfft?md5=ad15690552118024433c7403ca2be334&pid=1-s2.0-S2213007123001545-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138991451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vahdatpour C , Saha B , Younis M , Montuoro C , Timofte I , Rackauskas M , Emtiazjoo A
{"title":"A case report of a lung transplant recipient receiving belatacept in combination with low dose tacrolimus complicated by progressive multifocal leukoencephalopathy","authors":"Vahdatpour C , Saha B , Younis M , Montuoro C , Timofte I , Rackauskas M , Emtiazjoo A","doi":"10.1016/j.rmcr.2024.102028","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102028","url":null,"abstract":"<div><p>Belatacept is a novel T-cell costimulation blockade agent that has unresolved controversy in lung transplant recipients. Belatacept has been recognized as a calcineurin sparing agent for solid organ transplant recipients after reported success in renal transplant patients, despite limited evidence in other transplant recipients. We present the first case of a lung transplant recipient receiving Belatacept, in combination with low dose calcineurin inhibitor, who developed progressive multifocal leukoencephalopathy. While Belatacept without calcineurin inhibitor has been associated with increased risk of acute rejection in solid organ transplant recipients, its infectious risk profile in combination with calcineurin inhibitor remains unclear.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000510/pdfft?md5=c05bfdc3c0aef8182f59d5edca6397e1&pid=1-s2.0-S2213007124000510-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140816321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paraneoplastic pemphigus with airway involvement","authors":"Oscar A. Estrada Paz, Timothy J. Young","doi":"10.1016/j.rmcr.2024.102085","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102085","url":null,"abstract":"<div><p>We report a case of paraneoplastic pemphigus presenting with acute hypoxemic respiratory failure due to bronchiolitis obliterans which improved with high dose systemic corticosteroids, rituximab, niacinamide and doxycycline. This is the first report, to our knowledge, of paraneoplastic pemphigus with airway involvement which included niacinamide and doxycycline as therapy and demonstrated treatment response.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124001084/pdfft?md5=089d324a5ae8a71b3d47f0b655a0a8b4&pid=1-s2.0-S2213007124001084-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Femke Demolder , Samuel De Bontridder , Shane Hanon
{"title":"Katayama syndrome disguised as eosinophilic asthma with acute systemic symptoms and pulmonary nodules","authors":"Femke Demolder , Samuel De Bontridder , Shane Hanon","doi":"10.1016/j.rmcr.2024.102032","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102032","url":null,"abstract":"<div><h3>Background</h3><p>Katayama syndrome is an acute manifestation of schistosomiasis, a parasitic infection that manifests itself through a hypersensitivity reaction to migrating larvae and early egg deposition. Left undiagnosed and untreated, acute schistosomiasis can develop into chronic schistosomiasis which can lead to debilitating morbidity such as pulmonary hypertension. This case highlights that Katayama syndrome can also been seen in regions where the parasite is not endemic, as it occurs in travelers returning from endemic regions or in immigrants.</p></div><div><h3>Case presentation</h3><p>We describe the case of a 26-year-old asthmatic male, who presented with systemic symptoms including fever, myalgia, night sweats as well as gastro-intestinal and pulmonary complaints since five days. At presentation, there was a raised blood eosinophil count and nodular lesions were seen on computed tomography. After considering diagnoses such as tuberculosis, vasculitis and hypereosinophilic syndrome, it was repeated history taking that revealed that the patient had suffered from swimmer’s itch during a stay in Guinea. A stool sample showed microscopic presence of Schistosoma mansoni eggs, confirming the diagnosis of Katayama syndrome. The patient was treated with tapered corticosteroids to suppress the hypersensitivity reaction and praziquantel was added to cure the parasitic infection. This led to a complete resolution of the patients' symptoms and radiological abnormalities. Negative stool samples confirmed the eradication of the schistosomes.</p></div><div><h3>Conclusions</h3><p>Swimmer’s itch and Katayama syndrome are manifestations of acute schistosomiasis. It is important to recognize the syndrome, because early diagnosis and adequate treatment can prevent chronic disease and significant morbidity.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000558/pdfft?md5=652669e42dcd99df358e4bb246aa2037&pid=1-s2.0-S2213007124000558-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140842781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Xanthogranulomatous pleuritis induced by recurrent biliothorax due to a biliopleural fistula: The first case report in the literature","authors":"Moatasem Hussein Al-janabi , Hussein Kaada , Ghina Ismail , Dommar Roumieh , Zuheir Al-Shehabi","doi":"10.1016/j.rmcr.2024.102065","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102065","url":null,"abstract":"<div><p>Xanthogranulomatous pleuritis is an extremely rare pathological entity, characterized by the infiltration of foamy cells and multinucleated giant cells within the pleural space. This condition often mimics infectious and neoplastic processes, presenting significant diagnostic challenges. This report details the first documented case of xanthogranulomatous pleuritis induced by recurrent biliothorax due to a biliopleural fistula, presenting a unique clinical scenario. We describe the clinical presentation, diagnostic hurdles, and both the surgical and medical management of this case. The discovery of biliothorax, evidenced by pleural fluid bilirubin levels that exceed serum bilirubin levels, underscores the importance of considering biliothorax in the differential diagnosis of recurrent pleural effusions, particularly in patients with a history of trauma. This case emphasizes the need for heightened awareness and a multidisciplinary approach in the diagnosis and treatment to effectively manage this complex condition and prevent recurrence.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000881/pdfft?md5=360bfb07ca3bd5d990d0df0e8ad11ee5&pid=1-s2.0-S2213007124000881-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141294845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zentaro Saito , Takanori Ito , Takuma Imakita , Issei Oi , Osamu Kanai , Kohei Fujita
{"title":"Organizing pneumonia secondary to pulmonary cryptococcosis in immunocompromised patient","authors":"Zentaro Saito , Takanori Ito , Takuma Imakita , Issei Oi , Osamu Kanai , Kohei Fujita","doi":"10.1016/j.rmcr.2023.101975","DOIUrl":"https://doi.org/10.1016/j.rmcr.2023.101975","url":null,"abstract":"<div><p>Pulmonary cryptococcal infections are fungal infections that often occur in immunocompromised patients and present with a variety of radiographic patterns ranging from nodular to infiltrative shadows. In the present case, we experienced a rare case of organizing pneumonia due to cryptococcal infection in a 71-year-old woman with rheumatoid arthritis. Transbronchial lung biopsy showing fibrotic changes in the alveolar walls, small granulation lesions and cryptococcal organisms with positive Grocott staining. Serum cryptococcal antigen was also found to be positive. Based on these findings, we confirmed the diagnosis of secondary organizing pneumonia due to cryptococcal infection. Treatment with corticosteroids and antifungal drugs led to improvement of the cough and reduction of organizing pneumonia. In immunocompetent patients with organizing pneumonia, it is essential to perform bronchoscopic lung biopsies and serum antigen tests to search for the cause, whenever possible, as it may be due to an infection caused by Cryptococcus, as in the present case.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007123001703/pdfft?md5=62d3f2299ce18d380d7e6038dce765bc&pid=1-s2.0-S2213007123001703-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139100107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Grasmuk-Siegl , E. Xhelili , D. Doberer , M.H. Urban , A. Valipour
{"title":"Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO","authors":"E. Grasmuk-Siegl , E. Xhelili , D. Doberer , M.H. Urban , A. Valipour","doi":"10.1016/j.rmcr.2024.102057","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102057","url":null,"abstract":"<div><p>We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to massive bronchoconstriction with consecutive hypercapnic ventilatory failure veno-venous ECMO therapy had to be implemented. Hence, guideline directed asthma therapy a substantial bronchodilatation could not be achieved. After administration of a single dose Tezepelumab, a novel TLSP-inhibitor, and otherwise unchanged therapy we documented a significant reduction in intrinsic PEEP measured via a naso-gastric balloon catheter and a narrowing in the expiratory flow curve of the ventilator within 24 hours. The consecutive ventilatory improvement allowed the successful weaning from veno-venous ECMO therapy and invasive ventilation.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000807/pdfft?md5=a3fa3e38f1fc2e4ca207786485214f26&pid=1-s2.0-S2213007124000807-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141239006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}