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Hemorrhagic bronchitis caused by carbapenem-resistant Acinetobacter baumannii infection: A case report 耐碳青霉烯类鲍曼不动杆菌感染引起的出血性支气管炎：病例报告
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102010
Zifang Li , Yu Sheng , Dongdong Huang
{"title":"Hemorrhagic bronchitis caused by carbapenem-resistant Acinetobacter baumannii infection: A case report","authors":"Zifang Li ,&nbsp;Yu Sheng ,&nbsp;Dongdong Huang","doi":"10.1016/j.rmcr.2024.102010","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102010","url":null,"abstract":"<div><p>Carbapenem-resistant Acinetobacter baumannii (CR-AB) is rarely found in community respiratory infections, and there are currently no reports of hemorrhagic bronchitis caused by its infection. This work presents a case of bronchial bleeding in a diabetic patient who acquired a community-acquired infection of CR-AB. Treatment with levofloxacin was unsuccessful, as the patient's hemoptysis symptoms recur. The patient was treated with minocycline based on the drug sensitivity test, resulting in the disappearance of hemoptysis symptoms. The patient was subjected to follow-up by phone for three months and did not experience any further hemoptysis symptoms. This case highlights that CR-AB infection causes hemorrhagic bronchitis, and the antimicrobial treatment should be based on drug sensitivity results.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"48 ","pages":"Article 102010"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000339/pdfft?md5=b695535c77923580baf333c712ce00eb&pid=1-s2.0-S2213007124000339-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140138543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mixed invasive mucinous and non-mucinous adenocarcinoma of the lung with hematogenous metastases to multiple organs 肺部浸润性粘液腺癌和非粘液腺癌混合型，多器官血行转移
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102033
Shinya Otsuka , Kei Hiraoka , Nozomu Iwashiro , Noriko Kimura , Masanori Ohara
{"title":"Mixed invasive mucinous and non-mucinous adenocarcinoma of the lung with hematogenous metastases to multiple organs","authors":"Shinya Otsuka ,&nbsp;Kei Hiraoka ,&nbsp;Nozomu Iwashiro ,&nbsp;Noriko Kimura ,&nbsp;Masanori Ohara","doi":"10.1016/j.rmcr.2024.102033","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102033","url":null,"abstract":"<div><p>Mixed invasive mucinous and non-mucinous adenocarcinoma is a rare variant of lung adenocarcinoma. In pure invasive mucinous adenocarcinoma, multilobar and bilateral involvement are common, and extrathoracic metastasis is rare. Here, we report a case of mixed invasive mucinous and non-mucinous adenocarcinoma with distant metastasis to multiple organs without marked enlargement of the primary lung lesion. The pathological findings indicated high tumor invasiveness and the patient died 10 months after diagnosis despite chemoimmunotherapy. Further investigations are necessary to elucidate the clinical characteristics and appropriate management of mixed invasive mucinous and non-mucinous adenocarcinoma.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"49 ","pages":"Article 102033"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221300712400056X/pdfft?md5=9b283f23496b769e22317a230033aebc&pid=1-s2.0-S221300712400056X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140822840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of pleural mesothelioma with immunohistochemical staining positive for Krebs von den Lungen-6 一例胸膜间皮瘤免疫组化染色呈 Krebs von den Lungen-6 阳性的病例
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102040
Yugo Matsumura , Seidai Sato , Keiko Haji , Takeshi Masuda , Hiroto Yoneda , Hirokazu Ogino , Hirohisa Ogawa , Masaki Hanibuchi , Noboru Hattori , Yasuhiko Nishioka
{"title":"A case of pleural mesothelioma with immunohistochemical staining positive for Krebs von den Lungen-6","authors":"Yugo Matsumura ,&nbsp;Seidai Sato ,&nbsp;Keiko Haji ,&nbsp;Takeshi Masuda ,&nbsp;Hiroto Yoneda ,&nbsp;Hirokazu Ogino ,&nbsp;Hirohisa Ogawa ,&nbsp;Masaki Hanibuchi ,&nbsp;Noboru Hattori ,&nbsp;Yasuhiko Nishioka","doi":"10.1016/j.rmcr.2024.102040","DOIUrl":"10.1016/j.rmcr.2024.102040","url":null,"abstract":"<div><p>A 71-year-old male visited a hospital with a chief complaint of exertional dyspnea. A chest CT revealed multiple nodular lesions on the parietal pleura. Thoracoscopic pleural biopsy was performed resulting in a diagnosis of pleural mesothelioma with epithelioid type. When chemotherapy was initially initiated, his serum level of Krebs von den Lungen-6 (KL-6) was high. However, once chemotherapy was started, the serum KL-6 level gradually decreased with tumor shrinkage. Immunohistochemical staining revealed the expression of KL-6 from the tumor cells. This is the first report of KL-6 production directly from tumor cells in epithelial-type pleural mesothelioma.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"50 ","pages":"Article 102040"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000637/pdfft?md5=422f93b5e74a098bb1244f444c4a2db6&pid=1-s2.0-S2213007124000637-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141036552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of complete pathological response after comprehensive treatment in a patient with pulmonary adenocarcinoma with synchronous solitary brain metastasis 一例肺腺癌伴同步单发脑转移患者经综合治疗后获得完全病理反应的病例
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102060
Tomoya Tajiri, Keigo Sekihara, Motohisa Shibata, Takamitsu Hayakawa, Akikazu Kawase, Norihiko Shiiya, Kazuhito Funai
{"title":"A case of complete pathological response after comprehensive treatment in a patient with pulmonary adenocarcinoma with synchronous solitary brain metastasis","authors":"Tomoya Tajiri,&nbsp;Keigo Sekihara,&nbsp;Motohisa Shibata,&nbsp;Takamitsu Hayakawa,&nbsp;Akikazu Kawase,&nbsp;Norihiko Shiiya,&nbsp;Kazuhito Funai","doi":"10.1016/j.rmcr.2024.102060","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102060","url":null,"abstract":"<div><p>Systemic chemotherapy is the standard treatment for non-small cell lung cancer with distant metastases. However, additional local treatment for brain and thoracic lesions is recommended for patients with synchronous solitary brain metastases (SSBM). We report the case of a 71-year-old male diagnosed with pulmonary adenocarcinoma and SSBM. Pathological examination of the brain metastasis showed positive immunostaining for programmed cell death ligand 1 expression. After four cycles of chemotherapy with immune checkpoint inhibitors, right upper lobectomy with ND2a-1 was performed. Pathological examination revealed complete pathological response, and this patient is expected to experience long-term survival.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"50 ","pages":"Article 102060"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000832/pdfft?md5=ea6edd03941e4c9b9b9a8c96cba66ae7&pid=1-s2.0-S2213007124000832-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141292134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaplastic thyroid carcinoma transformation in a patient with advanced non-small cell lung cancer treated with PD-1 therapy: A case report 一名接受 PD-1 治疗的晚期非小细胞肺癌患者的甲状腺无节细胞癌转化：病例报告
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102070
Yoko Kataoka , Takuya Fujita , Jun Hanaoka
{"title":"Anaplastic thyroid carcinoma transformation in a patient with advanced non-small cell lung cancer treated with PD-1 therapy: A case report","authors":"Yoko Kataoka ,&nbsp;Takuya Fujita ,&nbsp;Jun Hanaoka","doi":"10.1016/j.rmcr.2024.102070","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.102070","url":null,"abstract":"<div><p>There have rarely been reports on the neoplastic transformation in other organs during immunotherapy for lung cancer. We report the case of a 71-year-old man who was diagnosed with advanced pulmonary adenocarcinoma and a thyroid tumor. The patient responded to chemoradiotherapy but developed a recurrence of pulmonary metastasis. Therefore, nivolumab was started, and a complete response for pulmonary metastasis was achieved. After 32 nivolumab cycles, he experienced neck pain, and the thyroid tumor grew rapidly. Histological examination revealed anaplastic thyroid carcinoma. Although rare, immunotherapy for lung cancer has the potential to induce neoplastic transformation in other organs.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"50 ","pages":"Article 102070"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000935/pdfft?md5=dc33cf144a9164a183d4eca04e3e99a4&pid=1-s2.0-S2213007124000935-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141292137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psyllium husk (Metamucil®) induced perennial asthma: A case report 车前子壳（Metamucil®）诱发常年性哮喘：病例报告
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102110
A.S. Marwaha , D. Cockcroft , B. Philipenko
{"title":"Psyllium husk (Metamucil®) induced perennial asthma: A case report","authors":"A.S. Marwaha ,&nbsp;D. Cockcroft ,&nbsp;B. Philipenko","doi":"10.1016/j.rmcr.2024.102110","DOIUrl":"10.1016/j.rmcr.2024.102110","url":null,"abstract":"<div><div>Metamucil®, a soluble fiber supplement for constipation, triggered new onset asthma symptoms in a 44-year-old sensitised nurse after a single inhaled exposure. After the initial event, she had no further exposures. She continued to face challenges with exacerbations, poor asthma control, and chronic cough. Despite 30 years of clinic follow-up, her asthma remained difficult to manage, requiring chronic prednisone. While tapering off corticosteroids, she developed polymyalgia rheumatica. This case underscores that psyllium in Metamucil® can cause reactions ranging from mild to severe, even with a single inhaled exposure, emphasising the need for caution in those without a history of asthma.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"52 ","pages":"Article 102110"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142359396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary lung cancer with pulmonary alveolar proteinosis treated with immune checkpoint inhibitor: A case report 用免疫检查点抑制剂治疗原发性肺癌合并肺泡蛋白沉着症病例报告
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2023.101976
Mika Horie, Kazuhisa Nakashima, Yoshihiro Amano, Yohei Shiratsuki, Kotaro Murakami, Takeshi Isobe, Yukari Tsubata
{"title":"Primary lung cancer with pulmonary alveolar proteinosis treated with immune checkpoint inhibitor: A case report","authors":"Mika Horie,&nbsp;Kazuhisa Nakashima,&nbsp;Yoshihiro Amano,&nbsp;Yohei Shiratsuki,&nbsp;Kotaro Murakami,&nbsp;Takeshi Isobe,&nbsp;Yukari Tsubata","doi":"10.1016/j.rmcr.2023.101976","DOIUrl":"https://doi.org/10.1016/j.rmcr.2023.101976","url":null,"abstract":"<div><p>Primary lung cancer with pulmonary alveolar proteinosis (PAP) is a rare condition. We present a case of a patient with primary lung cancer with PAP treated with an immune checkpoint inhibitor (ICI). A 62-year-old man was diagnosed with autoimmune PAP 8 years prior to current admission. Lung adenocarcinoma was found in his right lung, and platinum-based chemotherapy was administered, followed by atezolizumab. He experienced disease progression after atezolizumab treatment, whereas ICI-induced pneumonia or exacerbation of PAP did not occur. This indicates that ICI may be safely used in patients with primary lung cancer with PAP.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"47 ","pages":"Article 101976"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007123001715/pdfft?md5=fbae966b916333d0b9a1abaca78001c9&pid=1-s2.0-S2213007123001715-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139100108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classic biphasic pulmonary blastoma with endobronchial invasion in a 16-year-old male: A rare case report 一名 16 岁男性典型的双相肺泡瘤伴支气管内侵犯：罕见病例报告
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102143
Yousef Alsaffaf , Ahmed Aldolly , Hazem Arab , Nour Alsolaiman , Asaad Jalil , Simon Youssef , Fariz Ahmad
{"title":"Classic biphasic pulmonary blastoma with endobronchial invasion in a 16-year-old male: A rare case report","authors":"Yousef Alsaffaf ,&nbsp;Ahmed Aldolly ,&nbsp;Hazem Arab ,&nbsp;Nour Alsolaiman ,&nbsp;Asaad Jalil ,&nbsp;Simon Youssef ,&nbsp;Fariz Ahmad","doi":"10.1016/j.rmcr.2024.102143","DOIUrl":"10.1016/j.rmcr.2024.102143","url":null,"abstract":"<div><div>Pulmonary blastoma (PB) is a rare and aggressive lung neoplasm, representing 0.25 %–0.50 % of lung cancers and characterized by biphasic histology with both epithelial and mesenchymal components. We report a case of a 16-year-old male non-smoker presenting with hemoptysis and a 2-month history of dry cough and exertional dyspnea. Imaging revealed an ill-defined density in the left lung, and bronchoscopy identified a budding mass in the left bronchus. Biopsy results showed malignant spindle cells, with immunohistochemical staining positive for cytokeratin, vimentin, and TTF1, confirming classic biphasic pulmonary blastoma (CBPB). Further CT scans indicated multiple metastases in the right lung and bones. The patient was referred for palliative chemotherapy due to the tumor's aggressive nature. This case highlights the clinical presentation and diagnostic challenges of PB with endobronchial invasion.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"52 ","pages":"Article 102143"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Mycobacterium avium complex infection with vascular Ehlers–Danlos syndrome: A case report 肺分枝杆菌复合体感染合并血管性埃勒斯-丹洛斯综合征：病例报告
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.102119
Ken Okamura , Rintaro Noro , Toru Tanaka , Takeru Kashiwada , Yosuke Tanaka , Yoshinobu Saito , Kazue Fujita , Koichi Akutsu , Tomoko Sahara , Koichiro Kamio , Takeshi Yamada , Kazuo Kasahara , Masahiro Seike
{"title":"Pulmonary Mycobacterium avium complex infection with vascular Ehlers–Danlos syndrome: A case report","authors":"Ken Okamura ,&nbsp;Rintaro Noro ,&nbsp;Toru Tanaka ,&nbsp;Takeru Kashiwada ,&nbsp;Yosuke Tanaka ,&nbsp;Yoshinobu Saito ,&nbsp;Kazue Fujita ,&nbsp;Koichi Akutsu ,&nbsp;Tomoko Sahara ,&nbsp;Koichiro Kamio ,&nbsp;Takeshi Yamada ,&nbsp;Kazuo Kasahara ,&nbsp;Masahiro Seike","doi":"10.1016/j.rmcr.2024.102119","DOIUrl":"10.1016/j.rmcr.2024.102119","url":null,"abstract":"<div><p>A female patient developed multiple intestinal perforations at 31 and 43 years of age. Because of her family history of pneumothorax and intestinal perforation, Ehlers–Danlos syndrome (EDS) was suspected when she visited our hospital at 52 years. She was diagnosed with vascular Ehlers–Danlos syndrome (vEDS) and developed bilateral external iliac artery dissection. A CT scan at the time of admission revealed granular and infiltrative shadows in both lungs with bronchiectasis. The patient was also diagnosed with <em>Mycobacterium avium</em> complex (MAC) pulmonary disease, and drug susceptibility to clarithromycin was confirmed. After treatments with rifampicin, ethambutol, and clarithromycin were started, the acid-fast bacilli cultures taken from sputum were negative, and respiratory symptoms partially improved after about 1 month. vEDS is reportedly associated with lung diseases, such as pneumothorax and cystic lung lesions, but there are few reports of respiratory infections with vEDS. Moreover, there are no reports of complications associated with MAC disease. We report a case of vEDS with rare complications and suggest the possible mechanism of infection.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"52 ","pages":"Article 102119"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124001424/pdfft?md5=d31f07165f8ee1871af1702129a106d3&pid=1-s2.0-S2213007124001424-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142243542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection 伴有支气管溃疡的侵袭性肺粘液腺癌 - 感染 SARS-CoV-2 后痰量明显减少
IF 1.1
Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI: 10.1016/j.rmcr.2024.101982
Xin Liu , Xinyue Zhou , Xiaocong Zhang , Lingling Sun , Guangdan Zhao , Shitao Mao , Fangzhi Li , Xiu Gu , Paul J. Wolters , Shuo Liu
{"title":"Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection","authors":"Xin Liu ,&nbsp;Xinyue Zhou ,&nbsp;Xiaocong Zhang ,&nbsp;Lingling Sun ,&nbsp;Guangdan Zhao ,&nbsp;Shitao Mao ,&nbsp;Fangzhi Li ,&nbsp;Xiu Gu ,&nbsp;Paul J. Wolters ,&nbsp;Shuo Liu","doi":"10.1016/j.rmcr.2024.101982","DOIUrl":"https://doi.org/10.1016/j.rmcr.2024.101982","url":null,"abstract":"<div><p>Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep Cytologic Test. The case was considered an invasive mucinous adenocarcinoma of the lung combined with bronchorrhea. Significantly, the sputum volume declined rapidly and did not rise again when the patient was diagnosed with COVID-19 and treated with nirmatrelvir/ritonavir. This case is suggestive of studies related to regulatory mediators associated with bronchorrhea.</p></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"47 ","pages":"Article 101982"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213007124000054/pdfft?md5=b4c3c648b246ff3afbf8e71fd2ff6c3a&pid=1-s2.0-S2213007124000054-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139480095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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