Respiratory Medicine Case Reports最新文献_第10页

Mesalazine-associated lung fibrosis: case report and literature review 美沙拉嗪相关性肺纤维化：病例报告及文献复习

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102284

Nazlı Zeynep Uslu , Mustafa Hasan Adleh , Ebru Bilir , Fahad al-deen Kata , Merih Kalamanoğlu Balcı

{"title":"Mesalazine-associated lung fibrosis: case report and literature review","authors":"Nazlı Zeynep Uslu , Mustafa Hasan Adleh , Ebru Bilir , Fahad al-deen Kata , Merih Kalamanoğlu Balcı","doi":"10.1016/j.rmcr.2025.102284","DOIUrl":"10.1016/j.rmcr.2025.102284","url":null,"abstract":"<div><h3>Background</h3><div>Even though uncommon, drug-induced interstitial lung disease (DIILD) represents a serious adverse drug reaction. We report a case of a patient with a history of ulcerative colitis who was receiving mesalazine.</div></div><div><h3>Presentation</h3><div>The patient developed dyspnea, hypoxemia, and respiratory failure accompanied by resting oxygen desaturation. Initial CT imaging revealed bilateral perihilar ground-glass opacities along with focal areas of consolidation. Inflammatory markers were elevated, but procalcitonin levels remained persistently low; sputum cultures and multiplex PCR ruled against an infectious origin. Mesalazine was discontinued, and the patient's respiratory status improved dramatically. Follow-up CT revealed interval resolution of the pulmonary lesions, and a diagnosis of DIILD was clinically established.</div></div><div><h3>Conclusion</h3><div>This case emphasizes the importance of balancing clinical suspicion between steroid-related infectious risk and an uncommon drug reaction. We also identified similar Mesalazine-associated DIILD cases in the literature to demonstrate similar radiologic patterns, onset time, and outcomes.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"58 ","pages":"Article 102284"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asphyxiation due to obstructive fibrinous tracheal pseudomembrane after closure of repeated tracheostomy in a case of von Recklinghausen disease von Recklinghausen病反复气管切开术后阻塞性纤维性气管假膜致窒息1例

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102298

Taiki Hara , Ken Enda , Taku Maeda , Yohei Ikebe , Hideki Ujiie , Masahiro Onozawa

{"title":"Asphyxiation due to obstructive fibrinous tracheal pseudomembrane after closure of repeated tracheostomy in a case of von Recklinghausen disease","authors":"Taiki Hara , Ken Enda , Taku Maeda , Yohei Ikebe , Hideki Ujiie , Masahiro Onozawa","doi":"10.1016/j.rmcr.2025.102298","DOIUrl":"10.1016/j.rmcr.2025.102298","url":null,"abstract":"<div><h3>Background</h3><div>Obstructive fibrinous tracheal pseudomembrane (OFTP) is a rare but potentially fatal complication, most commonly reported after endotracheal intubation. Its occurrence following tracheostomy closure is poorly recognized.</div></div><div><h3>Case presentation</h3><div>We report a fatal case of OFTP in a 33-year-old man with von Recklinghausen disease who developed progressive airway obstruction following closure of a repeated tracheostomy. The patient had a history of multiple facial tumor resections requiring repeated tracheostomies due to orofacial deformities. After the eighth tracheostomy and successful tumor debulking, the tracheal cannula was removed on postoperative day 6. At that time, CT revealed only mild tracheal narrowing without intraluminal obstruction, and the patient remained asymptomatic. However, he was found in cardiopulmonary arrest on postoperative day 14. Postmortem CT showed near-complete tracheal obstruction and pulmonary edema. Autopsy confirmed a grayish-white pseudomembrane obstructing the tracheal lumen, with only a 2-mm residual gap. Histopathology revealed fibrinous exudate with neutrophilic infiltration, consistent with OFTP.</div></div><div><h3>Conclusion</h3><div>This case illustrates that OFTP can occur silently after tracheostomy closure and may lead to sudden death. Vigilant monitoring with CT or bronchoscopy should be considered in high-risk patients with repeated tracheal interventions.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"58 ","pages":"Article 102298"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145222198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety of brigatinib following alectinib-induced-pneumonitis: Case report 阿勒替尼致肺炎后布加替尼的安全性：病例报告

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102160

Blerina Resuli , Heidi Galarza , Laura Elsner , Diego Kauffmann-Guerrero , Jürgen Behr , Amanda Tufman

引用次数: 0

A stepwise approach for the management of bilateral chylothoraxes from cisterna chyli trauma 双侧乳糜胸由乳糜池外伤分步治疗

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102218

Vincent Phan , Syed H. Ali , Brady Olson , Raj Keriwala

引用次数: 0

New onset bronchial asthma following oral propranolol for infantile hemangioma 口服心得安治疗婴幼儿血管瘤后新发支气管哮喘

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102187

Yuki Yamaguchi, Satoshi Horino, Hiroki Miyabayashi, Haruka Aki, Katsushi Miura

引用次数: 0

A case study of airway management using laryngeal mask airway combined with Bronchial blocker for surgical treatment of tracheal tumors with pulmonary nodules 喉罩联合支气管阻滞剂在气管肿瘤合并肺结节手术治疗中的应用

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102208

Tingting Hu, Jun Yang, Min Xia

引用次数: 0

Primary pulmonary malignant melanoma with multiple metastases: a case report and literature review 多发转移的原发性肺恶性黑色素瘤1例报告及文献复习

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102221

JinFeng Chen , Min Ao , WeiYi Li , Xian Li , Li Yang

{"title":"Primary pulmonary malignant melanoma with multiple metastases: a case report and literature review","authors":"JinFeng Chen , Min Ao , WeiYi Li , Xian Li , Li Yang","doi":"10.1016/j.rmcr.2025.102221","DOIUrl":"10.1016/j.rmcr.2025.102221","url":null,"abstract":"<div><div>Primary malignant melanoma of lung (PMML) are relatively rare, accounting for about 0.4 % of all malignant melanomas and only 0.01 % of all lung tumors, and PMML with distant metastases found at diagnosis is extremely rare. A case of PMML presented as multiple solid and ground glass pulmonary nodules with brain, liver,intrapulmonary and lymph nodes metastasis was reported in this study. A 42-year-old man had a headache for 10 days after symptomatic treatment in the department of neurology in our hospital, but the above symptoms did not improved. Multiple nodules were considered by head MRI. Chest CT showed two solid nodules in the upper and lower lobes of the right lung and multiple ground glass nodules in both lungs. To further clarify the diagnosis,CT-guided percutaneous puncture biopsy of pulmonary nodule was performed. The pathology revealed malignant melanoma of <lung>.NRAS + BRAF gene test, showing BRAF gene exon 15 V600E mutation Dalafenib and trametinib were given targeted therapy after discharge. After 1 month follow-up, all lesions were significantly decreased. PMML presenting as solid and ground glass pulmonary nodules with multiple metastases is extremely rare. The early identification of pathological biopsy and genetic testing is crucial for precise treatment and enhancing prognosis.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"55 ","pages":"Article 102221"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary artery aneurysm as a rare manifestation of Alpha-1 antitrypsin deficiency 肺动脉动脉瘤是α -1抗胰蛋白酶缺乏的一种罕见表现

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102164

Mark A. Colantonio , Sanjana Aggarwal , Himanshu Deshwal

引用次数: 0

Solitary metastasis in the internal auditory canal from non-small cell lung carcinoma: A case report 非小细胞肺癌单发内耳道转移1例

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102175

Julie De Boos , Marie Bruyneel , Ionela Bold

{"title":"Solitary metastasis in the internal auditory canal from non-small cell lung carcinoma: A case report","authors":"Julie De Boos , Marie Bruyneel , Ionela Bold","doi":"10.1016/j.rmcr.2025.102175","DOIUrl":"10.1016/j.rmcr.2025.102175","url":null,"abstract":"<div><h3>Background</h3><div>Metastases to the internal auditory canal (IAC) are exceedingly rare. This case report details the case of a patient with a history of locally advanced non-small cell lung carcinoma (NSCLC) who developed a solitary IAC metastasis.</div></div><div><h3>Case presentation</h3><div>A 59-year-old active smoker was initially diagnosed with a locally advanced, unresectable stage IIIA Pancoast tumor (NSCLC, cT4N1M0) and treated with concurrent chemoradiation (cisplatin-pemetrexed) followed by immunotherapy (durvalumab). A subsequent PET CT scan indicated a complete metabolic response. Eighteen months later, the patient presented with rapidly progressing vertigo, left-sided facial palsy, and hearing loss. MRI revealed enhancement on nerves VII and VIII, with no intracranial metastasis or leptomeningeal enhancement. A biopsy via an endoscope-assisted retrosigmoid approach confirmed that it was an NSCLC metastasis. Gamma knife radiosurgery was initiated, resulting in a favorable clinical and radiological response.</div></div><div><h3>Discussion</h3><div>IAC metastases are rare, representing only 0.3%–0.7 % of all lesions in this anatomical space. Lung cancer is a common primary source. Clinically, IAC metastases manifest with acute onset and rapid symptom progression, often mimicking benign conditions. MRI with gadolinium contrast is the imaging modality of choice. Biopsy, though challenging, is sometimes crucial for definitive diagnosis. Gamma knife radiosurgery is a promising treatment, offering potential preservation of hearing and tumor control.</div></div><div><h3>Conclusion</h3><div>This rare case underscores the importance of considering metastatic IAC lesions in patients with a history of malignancy, highlights the feasibility of a biopsy via retrosigmoid approach for diagnosis, and demonstrates the effectiveness of gamma knife radiosurgery.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102175"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endobronchial tuberculosis mimicking malignancy: Lessons from a case report 支气管内结核模拟恶性：一个病例报告的教训

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102201

Tomohito Okano , Hajime Fujimoto , Toshiyuki Ito , Atsushi Tomaru , Haruko Saiki , Tatsuki Tsuruga , Taro Yasuma , Corina N. D'Alessandro-Gabazza , Esteban C. Gabazza , Tetsu Kobayashi

引用次数: 0