Respiratory Medicine Case Reports最新文献_第2页

Diagnostic challenges in differentiating mediastinal tuberculosis from mediastinal tumors: A case report 鉴别纵隔结核与纵隔肿瘤的诊断挑战：1例报告。

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102152

Aida, Noni Novisari Soeroso, Herani Mutia Riandini

引用次数: 0

A unique case of extranodal marginal zone lymphoma with synchronous pulmonary and dermatologic manifestations 结外边缘区淋巴瘤的独特病例，伴有肺部和皮肤的同步表现。

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102153

Carlo Arevalo , Fernando Camacho , Joseph Modrak

{"title":"A unique case of extranodal marginal zone lymphoma with synchronous pulmonary and dermatologic manifestations","authors":"Carlo Arevalo , Fernando Camacho , Joseph Modrak","doi":"10.1016/j.rmcr.2024.102153","DOIUrl":"10.1016/j.rmcr.2024.102153","url":null,"abstract":"<div><div>An 89-year-old male with a medical history of non-ischemic cardiomyopathy was initially admitted with acute hypoxic respiratory failure attributed to heart failure exacerbation. Aside from progressive dyspnea, a non-pruritic, non-painful rash and constitutional symptoms were reported. Initial work-up was remarkable for normocytic anemia, lymphopenia, mild hypercalcemia, and elevated inflammatory markers. Despite aggressive diuresis, his respiratory distress worsened requiring up-titration of supplemental oxygen (6–8L/min). Subsequent chest CT showed diffuse, ill-defined areas of consolidation and ground-glass opacities (GGOs) with areas of solid and ground-glass nodularity. Rheumatologic work-up was remarkable for mildly elevated ANA titer of 1:60, and positive anti-centromere antibody of 1.8 AI (normal range 0–0.9 AI). Infectious work-up was negative. Due to high oxygen requirements, tissue sampling was obtained by skin biopsy instead of bronchoscopy. After biopsy testing, prednisone 60 mg was started with posterior clinical and radiographic improvement. Biopsy results revealed cutaneous MZL. Follow-up PET scan showed persistent but improved diffuse GGOs and nodular opacities. Given the clinical presentation, imaging and skin biopsy results, the diagnosis was compatible with EMZL with synchronous pulmonary and skin manifestations. Empiric treatment with Rituximab and steroid taper was planned. At 6-month follow-up, the patient reported clinical and respiratory improvement.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102153"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of acute respiratory distress syndrome due to chlorine gas inhalation: Rapid progression with favorable ICU outcome 一例罕见的因吸入氯气引起的急性呼吸窘迫综合征：进展迅速，ICU预后良好。

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102148

Dung Thai Pham , Bang Ngoc Dao , Dung Tien Nguyen , Ba Van Dang , Dung Tien Le , Hung Manh Do , Loc Tich Hoang , Minh Tuan Ngo , Duong Minh Vu

{"title":"A rare case of acute respiratory distress syndrome due to chlorine gas inhalation: Rapid progression with favorable ICU outcome","authors":"Dung Thai Pham , Bang Ngoc Dao , Dung Tien Nguyen , Ba Van Dang , Dung Tien Le , Hung Manh Do , Loc Tich Hoang , Minh Tuan Ngo , Duong Minh Vu","doi":"10.1016/j.rmcr.2024.102148","DOIUrl":"10.1016/j.rmcr.2024.102148","url":null,"abstract":"<div><div>Acute respiratory distress syndrome (ARDS) secondary to chlorine gas inhalation is a rare yet critical condition that can lead to severe respiratory failure if not managed promptly. This case report presents a 43-year-old male who developed ARDS after accidental exposure to chlorine gas during pool maintenance. The patient's condition deteriorated rapidly, with symptoms progressing to acute pulmonary edema and severe hypoxemia, requiring immediate transfer to the intensive care unit (ICU). Initial treatment included non-invasive ventilation, but the patient soon required tracheal intubation and mechanical ventilation. Despite the rapid disease progression, the patient responded well to aggressive ICU management, including oxygen therapy, mechanical ventilation, and pharmacological support. Remarkably, within seven days, the patient fully recovered and was discharged in stable condition. This case highlights the potential for a good prognosis in ARDS due to chlorine gas inhalation compared to other etiologies, emphasizing the importance of timely intervention and specialized care in the ICU.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102148"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11700285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hereditary transthyretin amyloidosis incidentally diagnosed by video-associated lung surgery for lung cancer: A case report

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102170

Katsuhiro Itogawa , Shintaro Sato , Hideaki Yamakawa , Keiichi Akasaka , Masako Amano , Akiko Adachi , Hidekazu Matsushima

{"title":"Hereditary transthyretin amyloidosis incidentally diagnosed by video-associated lung surgery for lung cancer: A case report","authors":"Katsuhiro Itogawa , Shintaro Sato , Hideaki Yamakawa , Keiichi Akasaka , Masako Amano , Akiko Adachi , Hidekazu Matsushima","doi":"10.1016/j.rmcr.2025.102170","DOIUrl":"10.1016/j.rmcr.2025.102170","url":null,"abstract":"<div><div>Pulmonary involvement associated with transthyretin amyloidosis is a relatively uncommon presentation among many systemic symptoms. However, in recent times, several definitive treatments have been newly approved, thus the importance of diagnosing previously overlooked cases has been increasing. This report describes an incidentally diagnosed case with a pulmonary lesion. A 76-year-old male with a history of obstructive sleep apnea syndrome, bilateral carpal tunnel syndrome, and lumbar canal stenosis was presented with a 25mm right lower lobe nodule identified through a computed tomography conducted at an outpatient clinic. Lung cancer was suspected and the following thoracoscopic segmentectomy revealed a diagnosis of adenocarcinoma in situ. In addition, further pathological investigation of the background lung tissue revealed deposition of amyloid transthyretin (TTR), although no radiological findings suggestive of pulmonary amyloidosis were present. A genetic mutation screening test revealed pathological TTR gene mutation of heterozygous Tyr114His (p.Tyr134His). Thus, the diagnosis of hereditary transthyretin amyloidosis was made, and the subsequent investigation identified familial amyloid polyneuropathy. Finally, treatment with vutrisiran, a small interfering RNA (siRNA) targeting the TTR gene, was successfully initiated. Physicians need to be aware that unidentified amyloidosis may be diagnosed incidentally from a biopsied or resected specimen for another purpose. Diagnosing systemic amyloidosis that may otherwise be overlooked would enable patients to receive benefits from the definitive therapy.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102170"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic bronchopulmonary mycosis induced by pembrolizumab for bladder cancer: A case report

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102179

Hiroki Iida , Kenichiro Atsumi , Naohiro Kadoma , Sae Takashima , Yukari Shirakura , Ayana Suzuki , Kakeru Hisakane , Ryo Matsuoka , Koji Nagata , Masahiro Seike , Takashi Hirose

引用次数: 0

Adult granulosa cell tumor with rare pulmonary presentation

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102185

Mark G. Evans , Anthony Crymes , Adam Bedeir , David R. Braxton , Matthew J. Oberley , Robert T. Muldoon

引用次数: 0

A rare presentation of pulmonary transthyretin amyloidosis

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102189

Marc Assaad, Roshan Acharya, Elspeth Springsted, Frank Biscardi

{"title":"A rare presentation of pulmonary transthyretin amyloidosis","authors":"Marc Assaad, Roshan Acharya, Elspeth Springsted, Frank Biscardi","doi":"10.1016/j.rmcr.2025.102189","DOIUrl":"10.1016/j.rmcr.2025.102189","url":null,"abstract":"<div><div>Virchow described amyloidosis in 1853. Amyloidosis is the extracellular deposition of an insoluble misfolded polymerized tetramer of fibrillary protein that accumulates within tissues leading to organ dysfunction. Amyloidosis affects 10 people per one million every year. Specific varieties of amyloidosis result from diversely involved proteins. Tissue involvement can lead to multiorgan system dysfunction. Lung involvement from amyloidosis is very rare, and tissue biopsy is crucial for diagnosis. Genetic testing might be requested based on the suspected type. Lung involvement is very rare and mainly asymptomatic, and some cases are only diagnosed postmortem. When symptomatic, the clinical manifestations are nonspecific and include cough, dyspnea, and respiratory infections. The infiltrative process might affect pulmonary mechanics producing abnormal pulmonary function testing. Radiological manifestations of pulmonary amyloidosis involve the pleura, the tracheobronchial tree, the alveoli, and the mediastinal lymph nodes. Treatment of pulmonary amyloidosis is based on treating the underlying disease process. We present herein a case of 78-year-old male with senile cardiac amyloidosis, who presents to our clinic with multiple nodular pulmonary opacities.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"54 ","pages":"Article 102189"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital cervical lung herniation in an infant with arterial tortuosity syndrome

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102193

Amal Al-Naimi , Sara G. Hamad , Abdalla E. Zarroug

引用次数: 0

Effective management of refractory chylothorax associated with elderly onset Gorham-Stout disease: A case report

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102195

Haruna Yamaki , Masaru Ejima , Takaya Takeguchi , Chihiro Kagohashi , Shunya Hanawa , Natsushi Kubota , Kotaro Hanawa , Seishi Higashi , Satoko Hanada , Reiko Taki

{"title":"Effective management of refractory chylothorax associated with elderly onset Gorham-Stout disease: A case report","authors":"Haruna Yamaki , Masaru Ejima , Takaya Takeguchi , Chihiro Kagohashi , Shunya Hanawa , Natsushi Kubota , Kotaro Hanawa , Seishi Higashi , Satoko Hanada , Reiko Taki","doi":"10.1016/j.rmcr.2025.102195","DOIUrl":"10.1016/j.rmcr.2025.102195","url":null,"abstract":"<div><div>Gorham-Stout disease (GSD) is a rare vascular disease of lymphatic origin characterized by progressive osteolysis that commonly causes chylothorax owing to the leakage of lymphatic fluid from dissolved bones. We report a case of refractory chylothorax that was diagnosed as elderly onset GSD and treated successfully using multidisciplinary approaches. A 78-year-old male presented with persistent cough and shortness of breath caused by massive left pleural effusion. Thoracentesis and pleural biopsy revealed an initial diagnosis of idiopathic chylothorax. The patient underwent continuous thoracic drainage and several percutaneous thoracic duct embolization with subcutaneous octreotide acetate injection and a low-fat diet. Thoracoscopic surgery was performed to control the secondary empyema through the drain tube and repair the pleural lesions with lymphatic leakage. A sufficient decrease in pleural fluid volume allowed temporary removal of the thoracic drainage tube. However, thoracic drainage was resumed for refractory chylothorax when the patient gradually developed neck pain after three months. Computed tomography, magnetic resonance imaging, and bone scintigraphy revealed growing osteolytic lesions in the cervical and thoracic spine regions, and biopsy demonstrated numerous dilated thin-walled capillary structures with lymphocyte infiltrates. After diagnosing GSD and introducing sirolimus, the patient's symptoms improved, and thoracic drainage was discontinued. Multidisciplinary treatments successfully halted disease progression for over a year. The case report emphasizes the systematic examination to identify rare etiology in refractory chylothorax treatment.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"55 ","pages":"Article 102195"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchoscopic lung volume reduction complicated by ipsilateral pleural effusion 支气管镜下肺体积缩小合并同侧胸腔积液。

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Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102151

Marc Assaad, Wasif Shamsi, Anthony Loschner, Maria del Mar Cirino-Marcano

引用次数: 0