Maria João Azevedo , Andreia Garcia , Carolina F.F.A. Costa , Ana Filipa Ferreira , Inês Falcão-Pires , Bernd W. Brandt , Carla Ramalho , Egija Zaura , Benedita Sampaio-Maia
{"title":"The contribution of maternal factors to the oral microbiota of the child: Influence from early life and clinical relevance","authors":"Maria João Azevedo , Andreia Garcia , Carolina F.F.A. Costa , Ana Filipa Ferreira , Inês Falcão-Pires , Bernd W. Brandt , Carla Ramalho , Egija Zaura , Benedita Sampaio-Maia","doi":"10.1016/j.jdsr.2023.06.002","DOIUrl":"10.1016/j.jdsr.2023.06.002","url":null,"abstract":"<div><p>The mother represents one of the earliest sources of microorganisms to the child, influencing the acquisition and establishment of its microbiota in early life. However, the impact of the mother on the oral microbiota of the child from early life until adulthood remains to unveil. This narrative review aims to: i) explore the maternal influence on the oral microbiota of the child, ii) summarize the similarity between the oral microbiota of mother and child over time, iii) understand possible routes for vertical transmission, and iv) comprehend the clinical significance of this process for the child. We first describe the acquisition of the oral microbiota of the child and maternal factors related to this process. We compare the similarity between the oral microbiota of mother and child throughout time, while presenting possible routes for vertical transmission. Finally, we discuss the clinical relevance of the mother in the pathophysiological outcome of the child. Overall, maternal and non-maternal factors impact the oral microbiota of the child through several mechanisms, although the consequences in the long term are still unclear. More longitudinal research is needed to unveil the importance of early-life microbiota on the future health of the infant.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 191-202"},"PeriodicalIF":6.6,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9806798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin Yan , Qi Zhang , Xinyue Ma , Yewen Zhong , Hengni Tang , Sui Mai
{"title":"The mechanism of biomineralization: Progress in mineralization from intracellular generation to extracellular deposition","authors":"Xin Yan , Qi Zhang , Xinyue Ma , Yewen Zhong , Hengni Tang , Sui Mai","doi":"10.1016/j.jdsr.2023.06.005","DOIUrl":"10.1016/j.jdsr.2023.06.005","url":null,"abstract":"<div><p>Biomineralization is a highly regulated process that results in the deposition of minerals in a precise manner, ultimately producing skeletal and dental hard tissues. Recent studies have highlighted the crucial role played by intracellular processes in initiating biomineralization. These processes involve various organelles, such as the endoplasmic reticulum(ER), mitochondria, and lysosomes, in the formation, accumulation, maturation, and secretion of calcium phosphate (CaP) particles. Particularly, the recent in-depth study of the dynamic process of the formation of amorphous calcium phosphate(ACP) precursors among organelles has made great progress in the development of the integrity of the biomineralization chain. However, the precise mechanisms underlying these intracellular processes remain unclear, and they cannot be fully integrated with the extracellular mineralization mechanism and the physicochemical structure development of the mineralization particles. In this review, we aim to focus on the recent progress made in understanding intracellular mineralization organelles' processes and their relationship with the physicochemical structure development of CaP and extracellular deposition of CaP particles.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 181-190"},"PeriodicalIF":6.6,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9738924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Douglas Carvalho Caixeta , Luiz Renato Paranhos , Cauane Blumenberg , Marcelo Augusto Garcia-Júnior , Marco Guevara-Vega , Elisa Borges Taveira , Marjorie Adriane Costa Nunes , Thúlio Marquez Cunha , Ana Carolina Gomes Jardim , Carlos Flores-Mir , Robinson Sabino-Silva
{"title":"Salivary SARS-CoV-2 RNA for diagnosis of COVID-19 patients: A systematic review and meta-analysis of diagnostic accuracy","authors":"Douglas Carvalho Caixeta , Luiz Renato Paranhos , Cauane Blumenberg , Marcelo Augusto Garcia-Júnior , Marco Guevara-Vega , Elisa Borges Taveira , Marjorie Adriane Costa Nunes , Thúlio Marquez Cunha , Ana Carolina Gomes Jardim , Carlos Flores-Mir , Robinson Sabino-Silva","doi":"10.1016/j.jdsr.2023.06.004","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.06.004","url":null,"abstract":"<div><p>Accurate, self-collected, and non-invasive diagnostics are critical to perform mass-screening diagnostic tests for COVID-19. This systematic review with meta-analysis evaluated the accuracy, sensitivity, and specificity of salivary diagnostics for COVID-19 based on SARS-CoV-2 RNA compared with the current reference tests using a nasopharyngeal swab (NPS) and/or oropharyngeal swab (OPS). An electronic search was performed in seven databases to find COVID-19 diagnostic studies simultaneously using saliva and NPS/OPS tests to detect SARS-CoV-2 by RT-PCR. The search resulted in 10,902 records, of which 44 studies were considered eligible. The total sample consisted of 14,043 participants from 21 countries. The accuracy, specificity, and sensitivity for saliva compared with the NPS/OPS was 94.3 % (95 %CI = 92.1;95.9), 96.4 % (95 %CI = 96.1;96.7), and 89.2 % (95 %CI = 85.5;92.0), respectively. Besides, the sensitivity of NPS/OPS was 90.3 % (95 %CI = 86.4;93.2) and saliva was 86.4 % (95 %CI = 82.1;89.8) compared to the combination of saliva and NPS/OPS as the gold standard. Based on low to moderate certainty level these findings suggest a similarity in SARS-CoV-2 RNA detection between NPS/OPS swabs and saliva, and the association of both testing approaches as a reference standard can increase by 3.6 % the SARS-CoV-2 detection compared with NPS/OPS alone. This study supports saliva as an attractive alternative for diagnostic platforms to provide a non-invasive detection of SARS-CoV-2.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 219-238"},"PeriodicalIF":6.6,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49719901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor regarding “Diagnosis of cracked tooth: Clinical status and research progress”","authors":"Shreya Raj","doi":"10.1016/j.jdsr.2023.05.001","DOIUrl":"10.1016/j.jdsr.2023.05.001","url":null,"abstract":"","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 179-180"},"PeriodicalIF":6.6,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9814048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shih-Yun Wu , Ching-Yi Wu , Liang-Yu Lin , Yu-hsuan Chen , Hsin-Yi Huang , Yu-Lin Lai , Shyh-Yuan Lee
{"title":"Systemic antibiotics adjuvants to scaling and root planing in type 2 diabetic and periodontitis individuals: Systematic review with network meta-analysis","authors":"Shih-Yun Wu , Ching-Yi Wu , Liang-Yu Lin , Yu-hsuan Chen , Hsin-Yi Huang , Yu-Lin Lai , Shyh-Yuan Lee","doi":"10.1016/j.jdsr.2023.06.001","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.06.001","url":null,"abstract":"<div><p>Targeting inflammatory pathways is considered a common strategy to control type 2 diabetes (T2D) and periodontitis. This overview was to validate systemic antibiotics as an adjuvant to scaling and root planing (SRP) for the treatments of periodontal patients with T2D. Literature searches were conducted using Web of Science, PubMed, Cochrane, and EMBASE. Randomized trials comparing SRP and systemic antibiotics on glycated hemoglobin (HbA1c) and probing pocket depth (PPD) in adults with T2D and periodontitis were analyzed using network meta-analysis and meta-regression. At 3-month postintervention, meta-analyses of 16 studies revealed that SRP and SRP plus systemic antibiotics (SRPa) had similar significant effects in reducing HbA1c levels of − 0.72% and − 0.96% respectively. While SRP and SRPa also, respectively, reduced PPD of − 0.67 and − 0.89 mm, SRPa showed a better reduction than SRP. At 6-month postintervention, meta-analyses of 7 trials revealed that only SRP was effective in reducing HbA1c levels (−0.29%) but not SRPa. Although both SRP and SRPa still significantly reduced PPD by − 0.56 and − 0.81 mm, respectively, there was no difference between them. The current overview suggested that routine SRP alone is highly recommended for patients with T2D and periodontitis, since systemic antibiotics as an adjuvant provide a rather short-term effect.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 167-178"},"PeriodicalIF":6.6,"publicationDate":"2023-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49720067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beatriz Danieletto Sahm, Ana Beatriz Vilela Teixeira, Andréa Cândido dos Reis
{"title":"Graphene loaded into dental polymers as reinforcement of mechanical properties: A systematic review","authors":"Beatriz Danieletto Sahm, Ana Beatriz Vilela Teixeira, Andréa Cândido dos Reis","doi":"10.1016/j.jdsr.2023.06.003","DOIUrl":"10.1016/j.jdsr.2023.06.003","url":null,"abstract":"<div><p>Graphene compounds are incorporated into polymers in order to improve their mechanical properties and in dentistry this modification favors the clinical performance of these materials. The aim of this review was to evaluate graphene compounds, their concentrations, and their effect on mechanical properties as flexural, tensile, and compressive strength and hardness of polymethylmethacrylate (PMMA) and polyether-ether-ketone (PEEK) for dental application. The search was carried out in two steps in PubMed/Medline, Embase, Scopus, and Web of Science databases. The eligibility criteria included studies that incorporated pure graphene compounds into dental polymers and evaluated their mechanical properties. Were found 4984 results, of which 11 articles were included in this review. Graphene compounds: graphene oxide (GO), reduced graphene oxide (rGO), and graphene nanoplatelets (GNP) were incorporated into PMMA and PEEK, in concentrations ranging from 0.1 to 10 wt%. Concentrations lower than 0.75 wt% of GO in PMMA and 1 wt% of GNP in PEEK resulted in increased flexural, tensile, compression strength, and hardness of these polymers. It was concluded that the incorporation of graphene compounds in low concentrations increases dental polymers’ mechanical properties.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 160-166"},"PeriodicalIF":6.6,"publicationDate":"2023-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9708145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Athanasios E. Rigos , Katia Sarafidou , Eleana Kontonasaki
{"title":"Zirconia bond strength durability following artificial aging: A systematic review and meta-analysis of in vitro studies","authors":"Athanasios E. Rigos , Katia Sarafidou , Eleana Kontonasaki","doi":"10.1016/j.jdsr.2023.04.002","DOIUrl":"10.1016/j.jdsr.2023.04.002","url":null,"abstract":"<div><p>The present study systematically reviewed the literature regarding the bond strength durability of zirconia ceramics to resin-based luting cements after application of different bonding protocols and aging conditions. Electronic searches in PubMed, Scopus, and Web of Science databases were performed for relevant literature published between January 1st 2015 and November 15th 2022. Ninety-three (93) English language in-vitro studies were included. The percentage of the mean bond strength change was recorded prior to and after artificial aging, and the weighted mean values and 95% confidence intervals were calculated. Bonding protocols were classified based on the combination of MDP/non-MDP containing cement/primer and surface pretreatment, as well as the level of artificial aging performed. Alumina sandblasting (SA) was identified as the most frequently used surface pre-treatment while an insufficient number of studies was identified for each category of alternative surface treatments. The combination of MDP cement with tribochemical silica coating (TSC) or SA yielded more durable results after aging, while the application of SA and TSC improved bond durability when a non-MDP cement and a non-MDP primer were used. TSC may lead to increased bond durability compared to SA, whereas MDP cements may act similarly when combined with SA or TSC.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 138-159"},"PeriodicalIF":6.6,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/a7/main.PMC10238491.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9950938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tooth agenesis patterns and variants in PAX9: A systematic review","authors":"Narin Intarak , Karn Tongchairati , Kittipat Termteerapornpimol , Soranun Chantarangsu , Thantrira Porntaveetus","doi":"10.1016/j.jdsr.2023.04.001","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.04.001","url":null,"abstract":"<div><p>Mutations in <em>PAX9</em> are the most common genetic cause of tooth agenesis (TA). The aim of this study was to systematically review the profiles of the TA and <em>PAX9</em> variants and establish their genotype-phenotype correlation. Forty articles were eligible for 178 patients and 61 mutations (26 in frame and 32 null mutations). <em>PAX9</em> mutations predominantly affected molars, mostly the second molar, and the mandibular first premolar was the least affected. More missing teeth were found in the maxilla than the mandible, and with null mutations than in-frame mutations. The number of missing teeth was correlated with the locations of the in-frame mutations with the C-terminus mutations demonstrating the fewest missing teeth. The null mutation location did not influence the number of missing teeth. Null mutations in all locations predominantly affected molars. For the in-frame mutations, a missing second molar was commonly associated with mutations in the highly conserved paired DNA-binding domain, particularly the linking peptide (100% prevalence). In contrast, C-terminus mutations were rarely associated with missing second molars and anterior teeth, but were commonly related to an absent second premolar. These finding indicate that the mutation type and position contribute to different degrees of loss of <em>PAX9</em> function that further differentially influences the manifestations of TA. This study provides novel information on the correlation of the <em>PAX9</em> genotype-phenotype, aiding in the genetic counseling for TA.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 129-137"},"PeriodicalIF":6.6,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49739912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moritz Müller , Christine Schmucker , Johannes Naumann , Nadine Schlueter , Roman Huber , Ann-Kathrin Lederer
{"title":"Acupuncture in management of acute dental pain – A systematic review and meta-analysis","authors":"Moritz Müller , Christine Schmucker , Johannes Naumann , Nadine Schlueter , Roman Huber , Ann-Kathrin Lederer","doi":"10.1016/j.jdsr.2023.02.005","DOIUrl":"10.1016/j.jdsr.2023.02.005","url":null,"abstract":"<div><p>Acute dental pain is a common issue leading to dental consultation. Besides causal therapy, patients are treated with acupuncture, but efficacy in acute dental pain is still not clarified. We aimed to evaluate results of recent research to estimate the efficacy of acupuncture compared to pain-relieving approaches in treatment of acute dental pain. A systematic review of controlled trials being published between database inception and 2020 were conducted to evaluate the efficacy of acupuncture (alone or as complementary therapy) compared to local anesthesia or conventional analgesic medications in acute dental pain (intraoperatively and postoperatively) and to clarify whether acupuncture reduces the use of postoperative analgesic medications. Of 1672 publications, 23 publications met the inclusion criteria. From these, 11 randomized controlled trials (n = 668) reported on the efficacy of acupuncture on postoperative acute dental pain. Patients, who received acupuncture, showed lower pain scores postoperatively compared to sham acupuncture (Relative Risk −0.77, 95% Confidence interval −1.52 to −0.03). Overall, the results suggest a potential role of acupuncture in improving acute dental pain intraoperatively and postoperatively as well as improving the efficacy of local anesthesia, but the results are limited due to methodological shortcomings emphasizing the necessity for future high-quality research.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 114-128"},"PeriodicalIF":6.6,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/3b/main.PMC10025006.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9159675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naotaka Kishimoto , Takuro Sanuki , Younan Liu , Simon D. Tran , Kenji Seo
{"title":"Simulation training for medical emergencies of dental patients: A review of the dental literature","authors":"Naotaka Kishimoto , Takuro Sanuki , Younan Liu , Simon D. Tran , Kenji Seo","doi":"10.1016/j.jdsr.2023.02.004","DOIUrl":"10.1016/j.jdsr.2023.02.004","url":null,"abstract":"<div><p>In recent years, due to the aging of the population, the number of dental patients with comorbidities such as hypertension and diabetes has increased. Although it has been reported that these patients are increasingly developing medical emergencies during their dental treatments, many dental providers still do not possess the skills to manage medical emergencies appropriately. Simulation training is essential to improve this situation however, there is no report describing how to conduct an effective simulation in detail for dental office medical emergencies. The purpose of this review is to provide information on simulations that is effective and practical. The authors will highlight the key characteristics for providing effective simulation trainings, such as the selection of simulators, simulation locations, instructors, debriefings, methods for evaluating educational effectiveness, and the use of telesimulation as a method for simulation training due to the global COVID-19 pandemic. In addition, this review provides recommendations on tailoring an ideal simulation training course for those who wish to create one. The authors hope that this review will promote the spread of effective simulation training and in turn, contribute to improving the medical safety of dental patients.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 104-113"},"PeriodicalIF":6.6,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}