Japanese Dental Science Review最新文献

{"title":"Clinical, microbiological and immunological short, medium and long-term effects of different strains of probiotics as an adjunct to non-surgical periodontal therapy in patients with periodontitis. Systematic review with meta-analysis","authors":"Federico Ausenda ,&nbsp;Emanuele Barbera ,&nbsp;Elisabetta Cotti ,&nbsp;Eugenio Romeo ,&nbsp;Zuhair S Natto ,&nbsp;Nicola Alberto Valente","doi":"10.1016/j.jdsr.2023.02.001","DOIUrl":"10.1016/j.jdsr.2023.02.001","url":null,"abstract":"<div><h3>Introduction/objectives</h3><p>Probiotics have been proposed as adjuncts to non-surgical periodontal therapy (NSPT), however, the effect of their use remains unclear. The aim of this systematic review and meta-analysis was to analyze the evidence regarding the use of probiotics as an adjunct to NSPT in patients with periodontitis at a clinical, microbiological and immunological level.</p></div><div><h3>Data/sources</h3><p>A comprehensive search to identify clinical studies investigating the use of probiotics as an adjunct to NSPT in patients treated for periodontitis was performed. The data were grouped according to probiotic strain, frequency, form and duration of the probiotic intake.</p></div><div><h3>Study selection</h3><p>A total of 25 articles were included, all articles analysed clinical parameters, 10 included also microbiological findings and only 4 had immunological findings. The difference in probing depth (PD) between the test and the control group was statistically significant in favour of the test group when the probiotics were in the form of lozenges, administered twice a day and when the strain was <em>L. reuteri</em>. In terms of Clinical Attachment Level (CAL) gain the difference was statistically significant in the short and in the medium term but not in the long term. Due to the heterogeneity of the data, it was not possible to compare trough a meta analysis the immunological and the microbiological findings that were therefore analysed only descriptively.</p></div><div><h3>Conclusions</h3><p>The use of probiotics as an adjunct to NSPT in patients with periodontitis appears to provide additional clinical benefits that depend on the duration, the frequency, the form and the strain of probiotic used.</p></div><div><h3>Clinical significance</h3><p>This review not only shows data on the efficacy of probiotics in non-surgical periodontal therapy, but provides important information on their effects over time and which forms of probiotic administration might be most clinically useful.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 62-103"},"PeriodicalIF":6.6,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9465320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct pulp capping procedures – Evidence and practice","authors":"Rafiqul Islam ,&nbsp;Md Refat Readul Islam ,&nbsp;Toru Tanaka ,&nbsp;Mohammad Khursheed Alam ,&nbsp;Hany Mohamed Aly Ahmed ,&nbsp;Hidehiko Sano","doi":"10.1016/j.jdsr.2023.02.002","DOIUrl":"10.1016/j.jdsr.2023.02.002","url":null,"abstract":"<div><p>The aim of direct pulp capping (DPC) is to promote pulp healing and mineralized tissue barrier formation by placing a dental biomaterial directly over the exposed pulp. Successful application of this approach avoids the need for further and more extensive treatment. In order to ensure a complete pulp healing with the placement of restorative materials, a mineralized tissue barrier must form to protect the pulp from microbial invasion. The formation of mineralized tissue barrier can only be induced when there is a significant reduction in pulp inflammation and infection. Consequently, promoting the healing of pulp inflammation may provide a favorable therapeutic opportunity to maintain the sustainability of DPC treatment. Mineralized tissue formation was observed as the favorable reaction of exposed pulp tissue against a variety of dental biomaterials utilized for DPC. This observation reveals an intrinsic capacity of pulp tissue for healing. Therefore, this review focuses on the DPC and its healing procedure as well as the materials used for DPC treatment and their mechanisms of action to promote pulpal healing. In addition, the factors that can affect the healing process of DPC, clinical considerations and future perspective has been described.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 48-61"},"PeriodicalIF":6.6,"publicationDate":"2023-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10860893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Involvement of the Notch signaling system in alveolar bone resorption","authors":"Aleksandar Jakovljevic ,&nbsp;Nadja Nikolic ,&nbsp;Lucrezia Paternò Holtzman ,&nbsp;Pierre Tournier ,&nbsp;Alexis Gaudin ,&nbsp;Luca Cordaro ,&nbsp;Iva Milinkovic","doi":"10.1016/j.jdsr.2023.02.003","DOIUrl":"10.1016/j.jdsr.2023.02.003","url":null,"abstract":"<div><p>The Notch pathway is an evolutionarily preserved signaling pathway involved in a variety of vital cell functions. Additionally, it is one of the key regulators of inflammation, and controls the differentiation and function of different cells. Moreover, it was found to be involved in skeletal development and bone remodeling process. This review provides an overview of the involvement of the Notch signaling pathway in the pathogenesis of alveolar bone resorption in different forms of pathological conditions such as apical periodontitis, periodontal disease, and peri-implantitis. <em>In vitro</em> and in vivo evidence have confirmed the involvement of Notch signaling in alveolar bone homeostasis. Nonetheless, Notch signaling system, along with complex network of different biomolecules are involved in pathological process of bone resorption in apical periodontitis, periodontitis, and peri-implantitis. In this regard, there is a substantial interest to control the activity of this pathway in the treatment of disorders associated with its dysregulation. This review provides knowledge on Notch signaling and outlines its functions in alveolar bone homeostasis and alveolar bone resorption. Further investigations are needed to determine whether inhibition of the Notch signaling pathways might be beneficial and safe as a novel approach in the treatment of these pathological conditions.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 38-47"},"PeriodicalIF":6.6,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10860892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Japanese concept of considerations for evaluation of dental materials for tooth bleaching","authors":"Michiko Kurauchi ,&nbsp;Yuchi Sato ,&nbsp;Hiroyuki Tanishiro ,&nbsp;Ryosuke Morita ,&nbsp;Masayuki Otsuki ,&nbsp;Jun Kaneko ,&nbsp;Tomoyuki Tsubaki ,&nbsp;Bunsaku Yoshida ,&nbsp;Kota Aso ,&nbsp;Madoka Murakami ,&nbsp;Masuo Kondoh","doi":"10.1016/j.jdsr.2023.01.001","DOIUrl":"10.1016/j.jdsr.2023.01.001","url":null,"abstract":"<div><p>Recent advances in bleaching technology, such as bleaching ingredients, have accelerated the development of tooth whitening materials to change the color of natural teeth toward a lighter or whiter shade. Some bleaching materials are used for patients in combination with auxiliary medical devices to activate the bleaching materials by a light or heat source. Bleaching ingredients can be a poisonous and deleterious substance. Some bleaching materials are used in dental offices and the others at home. In clinical development of bleaching materials, appropriate evaluation of safety and efficacy is required according to the intended use. For appropriate and swift approval of the emerging bleaching materials, guideline on evaluation of dental whitening materials was discussed in a commissioned project by the Ministry of Health, Labour and Welfare of Japan for FY2021. Here, we summarize the current principles of the premarketing evaluation of the safety and efficacy.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 23-27"},"PeriodicalIF":6.6,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10774160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review in titanium-zirconium binary alloy for use in dental implants: Is there an ideal Ti-Zr composing ratio?","authors":"Qian Zhao,&nbsp;Takeshi Ueno,&nbsp;Noriyuki Wakabayashi","doi":"10.1016/j.jdsr.2023.01.002","DOIUrl":"10.1016/j.jdsr.2023.01.002","url":null,"abstract":"<div><p>Binary titanium-zirconium alloys have been studied as promising alternatives for Ti implants. The commercial Ti-15Zr alloy (Roxolid, Straumann) has been the major subject of numerous binary Ti-Zr alloys-related studies and has gained wide recognition in laboratory studies and clinical practices. However, binary Ti-Zr alloys of other composition ratios are still being investigated by researchers. This review aims to provide information on the potential of binary Ti-Zr alloys other than Ti-15Zr as implant materials in terms of mechanical strengths, chemical or electrochemical corrosion resistance capabilities, and biological performances. In addition, in this review, the Ti-15Zr alloy is discussed only when compared with other binary Ti-Zr alloys. From the included 26 studies, it is confirmed that the mechanical, chemical, electrochemical, and biological properties of Ti-Zr alloys are related to the Ti and Zr composition ratio in the alloy, phase, manufacturing process, and surface treatment. Among the studied alloys, α-or α′ phase-Ti-5 wt, 45 wt/30at, and 50 wt. %Zr exhibited relatively more promising results for further investigation. More research is necessary to evaluate the potential for future use of these materials for implants.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 28-37"},"PeriodicalIF":6.6,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10765009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative analysis of gene and protein expression in atherosclerosis-related pathways modulated by periodontal pathogens. Systematic review","authors":"Talia Yolanda Marroquin ,&nbsp;Sandra Guauque-Olarte","doi":"10.1016/j.jdsr.2022.12.001","DOIUrl":"10.1016/j.jdsr.2022.12.001","url":null,"abstract":"<div><p>The mechanisms modulated by periodontal pathogens in atherosclerosis are not fully understood. Aim: to perform an integrative analysis of gene and protein expression modulated by periodontal pathogens in cells and animal models for atherosclerosis.</p></div><div><h3>Methods</h3><p>Cochrane, PRISMA and AMSTAR2 guidelines for systematic reviews were followed. Data search was conducted in Pub-med, LILACS and Science Direct databases. Gene and protein expression data were collected from the included papers to perform an overrepresentation analysis using the Reactome Pathway Analysis tool and the KEGG database.</p></div><div><h3>Results</h3><p>Thirty-two papers were included in the review, they analyzed the effect of <em>Fusobacterium nucleatum</em>, <em>Porphyromonas gingivalis</em>, <em>Streptococcus anginosus</em>, <em>Streptococcus sanguinis</em>, <em>Tannerella forsythia</em>, and <em>Treponema denticola</em> or/and their virulent factors on gene and protein expression in human cells and animal models of atherosclerosis. Some of the modulated pathways include the immune system, programmed cell death, cellular responses to external stimuli, transport of small molecules, and signal transduction (p &lt; 0.05). Those pathways are known to be involved in different stages of atherosclerosis progression.</p></div><div><h3>Conclusion</h3><p>Based on the performed analysis, it is possible to state that periodontal pathogens have the potential to be a contributing factor for atherosclerosis even in absence of a high-fat diet or high shear stress.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 8-22"},"PeriodicalIF":6.6,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9100290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune dysregulation in immunoglobulin G4–related disease","authors":"Takashi Maehara ,&nbsp;Risako Koga ,&nbsp;Seiji Nakamura","doi":"10.1016/j.jdsr.2022.12.002","DOIUrl":"10.1016/j.jdsr.2022.12.002","url":null,"abstract":"<div><p>(IgG4-RD) is an immune-mediated fibrotic disorder characterized by severe resolution of inflammation and dysregulation of wound healing. IgG4-RD has been considered a unique disease since 2003, and significant progress has been achieved in the understanding of its essential features. The central role of B cells in IgG4-RD has been demonstrated by the robust clinical responsiveness of IgG4-RD to B cell depletion and the identification of multiple self-antigens that promote B cell expansion. Studies have increasingly revealed critical roles of these B cells and T cells in the pathogenesis of IgG4-RD, and we and other authors further identified CD4⁺ cytotoxic T lymphocytes as the main tissue-infiltrating CD4⁺ T cell subset in IgG4-RD tissues. Additionally, T follicular helper cell subsets that play a role in IgG4 isotype switching have been identified. In this review, we discuss research on IgG4-RD and the roles of B cell and T cell subsets, as well as the functions of CD4⁺ cytotoxic T cells in IgG4-RD pathogenesis. We highlight our findings from ongoing research using single-cell analysis of infiltrating CD4⁺ cytotoxic T cells, CD4⁺ follicular helper T cells, and infiltrating B cells in IgG4-RD and propose a model for the pathogenesis of IgG4-RD.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 1-7"},"PeriodicalIF":6.6,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9100283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hall technique for primary teeth: A systematic review and meta-analysis","authors":"Shijia Hu ,&nbsp;Alaa BaniHani ,&nbsp;Sarah Nevitt ,&nbsp;Michelle Maden ,&nbsp;Ruth M. Santamaria ,&nbsp;Sondos Albadri","doi":"10.1016/j.jdsr.2022.09.003","DOIUrl":"10.1016/j.jdsr.2022.09.003","url":null,"abstract":"<div><h3>Background</h3><p>There has been a debate about the use of Hall Technique (HT), whether it can be considered as a standard technique for the management of carious primary molars.</p></div><div><h3>Aim</h3><p>To summarise the evidence on HT for managing dentine caries in primary teeth.</p></div><div><h3>Design</h3><p>MEDLINE, Embase, CENTRAL and Epistemonikos databases were searched for clinical studies conducted from 2007 to 2021 evaluating HT in primary teeth. Two reviewers independently screened, data extracted and quality assessed the studies.</p></div><div><h3>Results</h3><p>Eleven publications from eight unique studies were included. Four were of low risk of bias overall and five studies were included in a meta-analysis. Overall, HT was 49 % (RR 1.49 [95 % CI: 1.15–1.93], I² =89.5 %, p &lt; 0.001) more likely to succeed. When compared to direct restorations, HT was 80 % more likely to succeed; while similar success was found when compared to conventional preformed metal crowns. HT was also over 6 times (RR 0.16 [95 %CI: 0.10–0.27], I² =0 %, p &lt; 0.001) less likely to fail. Most of the studies included proximal or multi-surface lesions.</p></div><div><h3>Conclusions</h3><p>HT is successful option for the management of caries in primary teeth, particularly for proximal or multi-surface dentine lesions. It is well-tolerated by children and acceptable to parent, with mild adverse effects reported.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"58 ","pages":"Pages 286-297"},"PeriodicalIF":6.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/ca/main.PMC9520271.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40389737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatigue bond strength of dental adhesive systems: Historical background of test methodology, clinical considerations and future perspectives","authors":"Akimasa Tsujimoto ,&nbsp;Wayne W. Barkmeier ,&nbsp;Erica C. Teixeira ,&nbsp;Toshiki Takamizawa ,&nbsp;Masashi Miyazaki ,&nbsp;Mark A. Latta","doi":"10.1016/j.jdsr.2022.05.001","DOIUrl":"10.1016/j.jdsr.2022.05.001","url":null,"abstract":"<div><p>Numerous laboratory evaluations have been conducted since Dr. Rafael Bowen introduced a method for determining the bond strengths of adhesive systems to dental substrates in 1965. Most of the past studies have been conducted using static bond strength tests, such as shear and tensile bond strength testing with either macro or micro sized specimens. These static bond strength tests are conducted using a monotonically increasing load in which stress is applied continuously until failure occurs. Although the type of stress that develops in static bond strength tests is not typically encountered in clinical situations, over the years clinicians have based their choice of adhesive systems for use in daily practice on the results of such tests. However, some well-known researchers have reported that the results obtained from static bond strength testing may have limited clinical relevance and should not be used only by themselves to make recommendations for clinical use. In clinical situations, restorations undergo cyclic stress during mastication at stress levels well below the breaking stress used in static bond strength tests. Thus, dynamic bond strength tests, using cyclic loading, should be more clinically relevant than static bond strength tests. Over 15 years, a testing method designed to assess fatigue bond strengths of dental adhesive systems has been developed through inter-collegial and international collaborative efforts. This review discusses the development of fatigue bond strength testing methodology, provides both a historical perspective and current information regarding available testing data for all categories of adhesive systems to enamel and dentin and perspectives on the future development of both adhesive systems and testing methods.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"58 ","pages":"Pages 193-207"},"PeriodicalIF":6.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/dc/main.PMC9250030.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40482913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and primary evidence of silver diamine fluoride on root caries management","authors":"Noriko Hiraishi ,&nbsp;Mahmoud Sayed ,&nbsp;Motoi Takahashi ,&nbsp;Toru Nikaido ,&nbsp;Junji Tagami","doi":"10.1016/j.jdsr.2021.11.002","DOIUrl":"10.1016/j.jdsr.2021.11.002","url":null,"abstract":"<div><p>Root caries is a growing problem for the worldwide aging population. Silver diamine fluoride (SDF) contains high concentrations of silver and fluoride ions, which prevents and arrests root caries, as well as dentin caries in the primary teeth of young children. Unlike other fluoride products that mainly reduce the formation of new carious lesions, 38% SDF is an effective agent that can efficiently arrest the carious process, remineralize the decayed dental tissues, and protect the tooth structure against the formation of new caries lesions. The use of SDF can result in more caries-resistant tooth structures. Despite these merits, its clinical disadvantages are the deep penetration of silver ions and sequential formation of silver compounds, which cause esthetic concern due to the discoloration and impaired efficacy of dentin bonding after using SDF. Thus, this narrative review, by addressing the primary experimental results and clinical applications of SDF on root caries, proposes management methods for root caries in conjunction with the application of SDF. We propose a two-visit treatment protocol to take advantage of the SDF application for root surface caries and utilize the discoloration caused by SDF.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"58 ","pages":"Pages 1-8"},"PeriodicalIF":6.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/31/main.PMC8672042.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39758634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}