Japanese Dental Science Review最新文献_第5页

Liquid biopsies based on cell-free DNA as a potential biomarker in head and neck cancer 基于无细胞DNA的液体活检作为癌症头颈部的潜在生物标志物

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-08-29 DOI: 10.1016/j.jdsr.2023.08.004

Óscar Rapado-González , Ana María Rodríguez-Ces , Rafael López-López , María Mercedes Suárez-Cunqueiro

{"title":"Liquid biopsies based on cell-free DNA as a potential biomarker in head and neck cancer","authors":"Óscar Rapado-González , Ana María Rodríguez-Ces , Rafael López-López , María Mercedes Suárez-Cunqueiro","doi":"10.1016/j.jdsr.2023.08.004","DOIUrl":"10.1016/j.jdsr.2023.08.004","url":null,"abstract":"<div><p>In the era of ‘precision medicine’, liquid biopsies based on cell-free DNA (cfDNA) have emerged as a promising tool in the oncology field. cfDNA from cancer patients is a mixture of tumoral (ctDNA) and non-tumoral DNA originated from healthy, cancer and tumor microenvironmental cells. Apoptosis, necrosis, and active secretion from extracellular vesicles represent the main mechanisms of cfDNA release into the physiological body fluids. Focused on HNC, two main types of cfDNA can be identified: the circulating cfDNA (ccfDNA) and the salivary cfDNA (scfDNA). Numerous studies have reported on the potential of cfDNA analysis as potential diagnostic, prognostic, and monitoring biomarker for HNC. Thus, ctDNA has emerged as an attractive strategy to detect cancer specific genetic and epigenetic alterations including DNA somatic mutations and DNA methylation patterns. This review aims to provide an overview of the up-to-date studies evaluating the value of the analysis of total cfDNA, cfDNA fragment length, and ctDNA analysis at DNA mutation and methylation level in HNC patients.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 289-302"},"PeriodicalIF":6.6,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10191014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral-gut axis as a novel biological mechanism linking periodontal disease and systemic diseases: A review 口腔-肠道轴作为牙周病和全身性疾病的一种新的生物学机制:综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-08-28 DOI: 10.1016/j.jdsr.2023.08.003

Kazuhisa Yamazaki

引用次数: 0

Bacterial single-cell transcriptomics: Recent technical advances and future applications in dentistry 细菌单细胞转录组学:最近的技术进展和未来在牙科中的应用

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-08-26 DOI: 10.1016/j.jdsr.2023.08.001

Ji-Hoi Moon , Dae-Hyun Roh , Kyu Hwan Kwack , Jae-Hyung Lee

{"title":"Bacterial single-cell transcriptomics: Recent technical advances and future applications in dentistry","authors":"Ji-Hoi Moon , Dae-Hyun Roh , Kyu Hwan Kwack , Jae-Hyung Lee","doi":"10.1016/j.jdsr.2023.08.001","DOIUrl":"10.1016/j.jdsr.2023.08.001","url":null,"abstract":"<div><p>Metagenomics and metatranscriptomics have enhanced our understanding of the oral microbiome and its impact on oral health. However, these approaches have inherent limitations in exploring individual cells and the heterogeneity within mixed microbial communities, which restricts our current understanding to bulk cells and species-level information. Fortunately, recent technical advances have enabled the application of single-cell RNA sequencing (scRNA-seq) for studying bacteria, shedding light on cell-to-cell diversity and interactions between host-bacterial cells at the single-cell level. Here, we address the technical barriers in capturing RNA from single bacterial cells and highlight pioneering studies from the past decade. We also discuss recent achievements in host-bacterial dual transcriptional profiling at the single-cell level. Bacterial scRNA-seq provides advantages in various research fields, including the investigation of phenotypic heterogeneity within genetically identical bacteria, identification of rare cell types, detection of antibiotic-resistant or persistent cells, analysis of individual gene expression patterns and metabolic activities, and characterization of specific microbe-host interactions. Integrating single-cell techniques with bulk approaches is essential to gain a comprehensive understanding of oral diseases and develop targeted and personalized treatment in dentistry. The reviewed pioneering studies are expected to inspire future research on the oral microbiome at the single-cell level.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 253-262"},"PeriodicalIF":6.6,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10236757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Periodontitis and periodontopathic bacteria as risk factors for rheumatoid arthritis: A review of the last 10 years 牙周炎和牙周病细菌是类风湿关节炎的危险因素:近10年的综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-08-26 DOI: 10.1016/j.jdsr.2023.08.002

Tetsuo Kobayashi , Peter Mark Bartold

{"title":"Periodontitis and periodontopathic bacteria as risk factors for rheumatoid arthritis: A review of the last 10 years","authors":"Tetsuo Kobayashi , Peter Mark Bartold","doi":"10.1016/j.jdsr.2023.08.002","DOIUrl":"10.1016/j.jdsr.2023.08.002","url":null,"abstract":"<div><p>Rheumatoid arthritis (RA) is characterized by chronic inflammatory destruction of joint tissue and is caused by an abnormal autoimmune response triggered by interactions between genetics, environmental factors, and epigenetic and posttranslational modifications. RA has been suggested to be interrelated with periodontitis, a serious form or stage of chronic inflammatory periodontal disease associated with periodontopathic bacterial infections, genetic predisposition, environmental factors, and epigenetic influences. Over the last decade, a number of animal and clinical studies have been conducted to assess whether or not periodontitis and associated periodontopathic bacteria constitute risk factors for RA. The present review introduces recent accumulating evidence to support the associations of periodontitis and periodontopathic bacteria with the risk of RA or the outcome of RA pharmacological treatment with disease-modifying antirheumatic drugs. In addition, the results from intervention studies have suggested an improvement in RA clinical parameters after nonsurgical periodontal treatment. Furthermore, the potential causal mechanisms underlying the link between periodontitis and periodontopathic bacteria and RA are summarized.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 263-272"},"PeriodicalIF":6.6,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10550735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of nanofibers as reinforcement on resin-based dental materials: A systematic review of in vitro studies 纳米纤维对树脂基牙科材料的增强作用:体外研究的系统综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-08-04 DOI: 10.1016/j.jdsr.2023.07.002

Laís Santos Albergaria , Cassiana Koch Scotti , Rafael Francisco Lia Mondelli , Heber Arbildo Vega , Clovis Mariano Faggion Jr , Juliana Fraga Soares Bombonatti , Marilia Mattar de Amoêdo Campos Velo

{"title":"Effect of nanofibers as reinforcement on resin-based dental materials: A systematic review of in vitro studies","authors":"Laís Santos Albergaria , Cassiana Koch Scotti , Rafael Francisco Lia Mondelli , Heber Arbildo Vega , Clovis Mariano Faggion Jr , Juliana Fraga Soares Bombonatti , Marilia Mattar de Amoêdo Campos Velo","doi":"10.1016/j.jdsr.2023.07.002","DOIUrl":"10.1016/j.jdsr.2023.07.002","url":null,"abstract":"<div><p>This systematic review provides an update on the effect of nanofibers as reinforcement on resin-based dental materials. A bibliographic search was conducted in MEDLINEPubMed, Embase, Web of Science, Scopus, BVS (LILACS, BBO e IBECS), Cochrane, LIVIVO, and gray literature (BDTD) to identify relevant articles up to May 2021. In vitro studies that evaluated and compared the mechanical properties of nanofibers resin-based composite materials, were eligible. No publication year or language restriction was applied, and methodological quality was assessed using two methods. In a total of 6100 potentially eligible studies, 81 were selected for full-text analysis and 35 were included for qualitative analysis. Of the 35 included studies, a total of 29 studies evaluated the flexural strength (FS) of the materials. These groups were distinguished according to the resin-based materials tested and nanofiber types. Most of the studies evaluated materials composed of glass fibers and demonstrated higher values of FS when compared to resin-based materials without nanofibers. The incorporation of nanofibers into resin-based dental materials improved the mechanical properties compared to resin-based materials without nanofibers, suggesting better performance of these materials in high-stressbearing application areas. Further clinical studies are required to confirm the efficacy of resin-based materials with nanofibers.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 239-252"},"PeriodicalIF":6.6,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tooth agenesis: An overview of diagnosis, aetiology and management 牙齿发育不全:诊断、病因和治疗的综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-07-07 DOI: 10.1016/j.jdsr.2023.07.001

Maurice J. Meade, Craig W. Dreyer

引用次数: 1

Risk factors of cognitive impairment: Impact of decline in oral function 认知障碍的危险因素:口腔功能下降的影响

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-06-29 DOI: 10.1016/j.jdsr.2023.06.006

Toshihito Takahashi, Kodai Hatta, Kazunori Ikebe

{"title":"Risk factors of cognitive impairment: Impact of decline in oral function","authors":"Toshihito Takahashi, Kodai Hatta, Kazunori Ikebe","doi":"10.1016/j.jdsr.2023.06.006","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.06.006","url":null,"abstract":"<div><p>Cognitive impairment and subsequent dementia are the major causes of disability and need for nursing care among older people in worldwide. The purpose is to review well-known risk factors for cognitive impairment and dementia, focusing on the relationship between decline in oral function and current prevention strategies. Various non-modifiable and modifiable risk factors are related to cognitive impairment. Effects of oral function to cognitive impairment is not yet well recognized in the medical community, although masticatory function, occlusal force, and number of teeth have been reported to be related to cognitive function. Furthermore, occlusal force rather than number of teeth was significantly related to the early stages of cognitive impairment, and that a decline in occlusal force seemed to lead to cognitive impairment directly and indirectly through dietary intake. This relationship was significant only for occlusal force, which may be associated with the early stages of cognitive decline. Nutritional change caused by reduced masticatory function is suggested as a possible explanation. Therefore, rehabilitation or maintenance of oral function should be sought to prevent cognitive impairment.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 203-208"},"PeriodicalIF":6.6,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49735780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The contribution of maternal factors to the oral microbiota of the child: Influence from early life and clinical relevance 母亲因素对儿童口腔微生物群的影响：早期生活的影响和临床相关性

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-06-26 DOI: 10.1016/j.jdsr.2023.06.002

Maria João Azevedo , Andreia Garcia , Carolina F.F.A. Costa , Ana Filipa Ferreira , Inês Falcão-Pires , Bernd W. Brandt , Carla Ramalho , Egija Zaura , Benedita Sampaio-Maia

{"title":"The contribution of maternal factors to the oral microbiota of the child: Influence from early life and clinical relevance","authors":"Maria João Azevedo , Andreia Garcia , Carolina F.F.A. Costa , Ana Filipa Ferreira , Inês Falcão-Pires , Bernd W. Brandt , Carla Ramalho , Egija Zaura , Benedita Sampaio-Maia","doi":"10.1016/j.jdsr.2023.06.002","DOIUrl":"10.1016/j.jdsr.2023.06.002","url":null,"abstract":"<div><p>The mother represents one of the earliest sources of microorganisms to the child, influencing the acquisition and establishment of its microbiota in early life. However, the impact of the mother on the oral microbiota of the child from early life until adulthood remains to unveil. This narrative review aims to: i) explore the maternal influence on the oral microbiota of the child, ii) summarize the similarity between the oral microbiota of mother and child over time, iii) understand possible routes for vertical transmission, and iv) comprehend the clinical significance of this process for the child. We first describe the acquisition of the oral microbiota of the child and maternal factors related to this process. We compare the similarity between the oral microbiota of mother and child throughout time, while presenting possible routes for vertical transmission. Finally, we discuss the clinical relevance of the mother in the pathophysiological outcome of the child. Overall, maternal and non-maternal factors impact the oral microbiota of the child through several mechanisms, although the consequences in the long term are still unclear. More longitudinal research is needed to unveil the importance of early-life microbiota on the future health of the infant.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 191-202"},"PeriodicalIF":6.6,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9806798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The mechanism of biomineralization: Progress in mineralization from intracellular generation to extracellular deposition 生物矿化机制:矿化从胞内生成到胞外沉积的研究进展

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-06-24 DOI: 10.1016/j.jdsr.2023.06.005

Xin Yan , Qi Zhang , Xinyue Ma , Yewen Zhong , Hengni Tang , Sui Mai

{"title":"The mechanism of biomineralization: Progress in mineralization from intracellular generation to extracellular deposition","authors":"Xin Yan , Qi Zhang , Xinyue Ma , Yewen Zhong , Hengni Tang , Sui Mai","doi":"10.1016/j.jdsr.2023.06.005","DOIUrl":"10.1016/j.jdsr.2023.06.005","url":null,"abstract":"<div><p>Biomineralization is a highly regulated process that results in the deposition of minerals in a precise manner, ultimately producing skeletal and dental hard tissues. Recent studies have highlighted the crucial role played by intracellular processes in initiating biomineralization. These processes involve various organelles, such as the endoplasmic reticulum(ER), mitochondria, and lysosomes, in the formation, accumulation, maturation, and secretion of calcium phosphate (CaP) particles. Particularly, the recent in-depth study of the dynamic process of the formation of amorphous calcium phosphate(ACP) precursors among organelles has made great progress in the development of the integrity of the biomineralization chain. However, the precise mechanisms underlying these intracellular processes remain unclear, and they cannot be fully integrated with the extracellular mineralization mechanism and the physicochemical structure development of the mineralization particles. In this review, we aim to focus on the recent progress made in understanding intracellular mineralization organelles' processes and their relationship with the physicochemical structure development of CaP and extracellular deposition of CaP particles.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 181-190"},"PeriodicalIF":6.6,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9738924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary SARS-CoV-2 RNA for diagnosis of COVID-19 patients: A systematic review and meta-analysis of diagnostic accuracy 唾液SARS-CoV-2 RNA诊断COVID-19患者:诊断准确性的系统回顾和荟萃分析

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2023-06-21 DOI: 10.1016/j.jdsr.2023.06.004

Douglas Carvalho Caixeta , Luiz Renato Paranhos , Cauane Blumenberg , Marcelo Augusto Garcia-Júnior , Marco Guevara-Vega , Elisa Borges Taveira , Marjorie Adriane Costa Nunes , Thúlio Marquez Cunha , Ana Carolina Gomes Jardim , Carlos Flores-Mir , Robinson Sabino-Silva

{"title":"Salivary SARS-CoV-2 RNA for diagnosis of COVID-19 patients: A systematic review and meta-analysis of diagnostic accuracy","authors":"Douglas Carvalho Caixeta , Luiz Renato Paranhos , Cauane Blumenberg , Marcelo Augusto Garcia-Júnior , Marco Guevara-Vega , Elisa Borges Taveira , Marjorie Adriane Costa Nunes , Thúlio Marquez Cunha , Ana Carolina Gomes Jardim , Carlos Flores-Mir , Robinson Sabino-Silva","doi":"10.1016/j.jdsr.2023.06.004","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.06.004","url":null,"abstract":"<div><p>Accurate, self-collected, and non-invasive diagnostics are critical to perform mass-screening diagnostic tests for COVID-19. This systematic review with meta-analysis evaluated the accuracy, sensitivity, and specificity of salivary diagnostics for COVID-19 based on SARS-CoV-2 RNA compared with the current reference tests using a nasopharyngeal swab (NPS) and/or oropharyngeal swab (OPS). An electronic search was performed in seven databases to find COVID-19 diagnostic studies simultaneously using saliva and NPS/OPS tests to detect SARS-CoV-2 by RT-PCR. The search resulted in 10,902 records, of which 44 studies were considered eligible. The total sample consisted of 14,043 participants from 21 countries. The accuracy, specificity, and sensitivity for saliva compared with the NPS/OPS was 94.3 % (95 %CI = 92.1;95.9), 96.4 % (95 %CI = 96.1;96.7), and 89.2 % (95 %CI = 85.5;92.0), respectively. Besides, the sensitivity of NPS/OPS was 90.3 % (95 %CI = 86.4;93.2) and saliva was 86.4 % (95 %CI = 82.1;89.8) compared to the combination of saliva and NPS/OPS as the gold standard. Based on low to moderate certainty level these findings suggest a similarity in SARS-CoV-2 RNA detection between NPS/OPS swabs and saliva, and the association of both testing approaches as a reference standard can increase by 3.6 % the SARS-CoV-2 detection compared with NPS/OPS alone. This study supports saliva as an attractive alternative for diagnostic platforms to provide a non-invasive detection of SARS-CoV-2.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"59 ","pages":"Pages 219-238"},"PeriodicalIF":6.6,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49719901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2