The Open Ophthalmology Journal最新文献

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Ocular Findings and Blurring of Vision Associated with COVID-19 Virus during Pandemics in Iraq 伊拉克大流行期间与 COVID-19 病毒有关的眼部症状和视力模糊现象
The Open Ophthalmology Journal Pub Date : 2024-02-02 DOI: 10.2174/0118743641277380231212063936
Zainab Adel Hashim, Suzan Kahatan M. Salih, Marwan Younis Abdulla
{"title":"Ocular Findings and Blurring of Vision Associated with COVID-19 Virus during Pandemics in Iraq","authors":"Zainab Adel Hashim, Suzan Kahatan M. Salih, Marwan Younis Abdulla","doi":"10.2174/0118743641277380231212063936","DOIUrl":"https://doi.org/10.2174/0118743641277380231212063936","url":null,"abstract":"\u0000 \u0000 Coronavirus disease 2019 (COVID-19) emerged with a number of ophthalmologic manifestations. The most significant ocular symptoms included conjunctival discharge, redness, tears, itching, and a feeling of a foreign body in the eye.\u0000 \u0000 \u0000 \u0000 To review and critically appraise ophthalmologic manifestations of COVID-19 in the form of rate and severity of visual impairment following ocular and systemic COVID-19 infections.\u0000 \u0000 \u0000 \u0000 A cross-sectional study that was carried out at the outpatients’ clinic in Al-Diwaniyah Teaching Hospital from October 2020 to October 2022 were 135 patients seeking advice regarding their ocular complaints. They are PCR and /or CT-scan approved COVID-19 infection. Comprehensive eye examination done for these patients started with visual acuity assessment by Snellen chart, then refraction followed by examination of the eye and its adnexa by slit lamp for signs of inflammation.\u0000 \u0000 \u0000 \u0000 The patients had a mean age of 47.5 years, and the rate of blurring of vision was 39.3%, whether they had ocular manifestation or not, and it showed substantial association with disease severity.\u0000 \u0000 \u0000 \u0000 COVID-19 infection was associated with visual impairment, and the ophthalmologic manifestations severity was related to systemic morbidity.\u0000","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"45 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139809633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel approach for Corneal Remodeling of Laser Asymmetric Keratectomy with Collagen Cross Linking in Patients with Keratoconus Suspect 激光非对称角膜切除术与胶原蛋白交联技术为疑似角膜炎患者重塑角膜的新方法
The Open Ophthalmology Journal Pub Date : 2024-01-30 DOI: 10.2174/0118743641282093231228053309
Ji Sang Min, Dongcho Lee, SeongSu Lee, Pyung Moo Min
{"title":"A Novel approach for Corneal Remodeling of Laser Asymmetric Keratectomy with Collagen Cross Linking in Patients with Keratoconus Suspect","authors":"Ji Sang Min, Dongcho Lee, SeongSu Lee, Pyung Moo Min","doi":"10.2174/0118743641282093231228053309","DOIUrl":"https://doi.org/10.2174/0118743641282093231228053309","url":null,"abstract":"\u0000 \u0000 True Keratoconus Suspect (KCS) is an absolute contraindication to LASIK or Photorefractive Keratectomy (PRK) due to postoperative ectasia.\u0000 \u0000 \u0000 \u0000 To evaluate the effectiveness of laser asymmetric keratectomy with collagen cross-linking (L-LAK-CXL) in myopic patients with suspected keratoconus (KCS).\u0000 \u0000 \u0000 \u0000 This study included 40–44-year-old four myopic (-2.50 to -5.50 D) patients (4 eyes), of KCS with focal corneal steepening over +47.0 D and peripheral asymmetric corneal thickness. L-LAK-CXL was performed for both original ablation of refractive errors and crescentic customized ablation of the thicker peripheral cornea selectively and myopic changes due to the ablation of the peripheral thicker cornea simultaneously, followed by CXL without the epithelium. We compared preoperative and postoperative ocular findings, including corneal symmetry (total differences of the corneal thickness in four directions (SUM) and decentration of the thinnest point (DISTANCE)) and tear break-out time (TBUT).\u0000 \u0000 \u0000 \u0000 From preoperative to postoperative, spherical equivalent (D, average) decreased from -3.38 to -0.34, uncorrected distance visual acuity (LogMAR) increased from 0.53 to 0.00, and Kmax (average D) had decreased from +48.3 to +43.95, central pachymetry (CP, µm, average) decreased from 574 to 511. Postoperative corneal symmetry increased markedly owing to decreased SUM and DISTANCE scores. TBUT increased over 15 s postoperatively. No post-operative corneal ectasia was observed.\u0000 \u0000 \u0000 \u0000 L-LAK-CXL improved corneal symmetry in myopic patients with KCS by reducing SUM, decreasing DISTANCE and Kmax, increasing TBUT, and demonstrating good postoperative visual outcomes.\u0000","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"13 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140482659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Smartphone-based Fundus Photo in Vision Threatening Diabetic Retinopathy Screening: Developing Country Perspective 基于智能手机的眼底照片在视力受到威胁的糖尿病视网膜病变筛查中的功效:发展中国家的视角
The Open Ophthalmology Journal Pub Date : 2024-01-19 DOI: 10.2174/0118743641281527240116095349
Mia Nursalamah, Feti Karfiati, Nina Ratnaningsih, Sri Hudaya Widihastha
{"title":"Efficacy of Smartphone-based Fundus Photo in Vision Threatening Diabetic Retinopathy Screening: Developing Country Perspective","authors":"Mia Nursalamah, Feti Karfiati, Nina Ratnaningsih, Sri Hudaya Widihastha","doi":"10.2174/0118743641281527240116095349","DOIUrl":"https://doi.org/10.2174/0118743641281527240116095349","url":null,"abstract":"\u0000 \u0000 Vision-threatening diabetic retinopathy (VTDR) is a microvascular retinal complication caused by diabetes mellitus, which may lead to blindness if left untreated. One of the most effective methods to prevent diabetic-related ocular complications is through diabetic retinopathy (DR) screening. The community rarely carries out diabetic retinopathy-related eye examinations because using non-portable fundus photographs as its gold standard is costly and impracticable. This study aimed to determine the accuracy of smartphone-based fundus photographs as a practical and affordable tool for VTDR screening in developing countries.\u0000 \u0000 \u0000 \u0000 This cross-sectional study used a consecutive technique at Cicendo National Eye Hospital, Indonesia. Patients with diabetes mellitus aged ≥20 years were evaluated for two-field mydriatic fundus photos using a non-portable fundus photo and a smartphone- based fundus photo utilizing the i-Spot fundus adapter. Results were analyzed to determine diagnostic test parameters.\u0000 \u0000 \u0000 \u0000 Two hundred and nineteen two-field mydriatic fundus photos were obtained from 139 patients. Smartphone-based fundus photography demonstrated a sensitivity of 98.4% (CI 96.6–100%), a specificity of 87.1% (CI 75.3–98.9%), a positive predictive value of 97.9% (CI 95.9–99.9%), a negative predictive value of 90.0% (CI 79.3–100%), and an accuracy of 96.8% (CI 94.5–99.8%).\u0000 \u0000 \u0000 \u0000 The use of smartphone-captured fundus images proves to be a reliable screening method for VTDR. This tool has the potential to effectively screen the population, helping prevent future visual loss attributed to the disease.\u0000","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"79 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140503254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymorphisms of Aldose Reductase (ALR2) Regulatory Gene are Risk Factors for Diabetic Retinopathy in Type-2 Diabetes Mellitus Patients in Bali, Indonesia. 醛糖还原酶(ALR2)调控基因多态性是印尼巴厘岛2型糖尿病患者糖尿病视网膜病变的危险因素
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-10-18 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010281
Desak Made Wihandani, Ketut Suastika, I Nyoman Agus Bagiada, Safarina G Malik
{"title":"Polymorphisms of Aldose Reductase (ALR2) Regulatory Gene are Risk Factors for Diabetic Retinopathy in Type-2 Diabetes Mellitus Patients in Bali, Indonesia.","authors":"Desak Made Wihandani,&nbsp;Ketut Suastika,&nbsp;I Nyoman Agus Bagiada,&nbsp;Safarina G Malik","doi":"10.2174/1874364101812010281","DOIUrl":"https://doi.org/10.2174/1874364101812010281","url":null,"abstract":"<p><strong>Aim: </strong>The study aimed to elucidate whether the polymorphisms of the aldose reductase regulatory gene were risk factors for Diabetic Retinopathy (DR) in type-2 diabetes mellitus (T2DM) patients in Bali.</p><p><strong>Methods: </strong>This is a case-control study including 35 cases of T2DM patients with DR paired with 35 cases with non-DR as controls. PCR analysis and DNA-sequencing were carried out to detect the C(-106)T and C(-12)G polymorphisms at the regulatory region of Aldose Reductase (ALR2) gene. Genotype and allele distributions were analyzed by Chi-squared test and independent t-and Mann-Whitney U tests were used to analyze other data.</p><p><strong>Results: </strong>Among all subjects in both groups, the baseline characteristics were homogenous except for systolic blood pressure, fasting blood glucose and 2-hours post-prandial blood glucose. This study found two polymorphisms, C(-104)T and C(-9)G, in the regulatory region of ALR2 gene. The result showed that the C(-104)T polymorphism was a risk factor for DR (OR=36; 95% CI = 4.43-292.85; <i>p</i>=0.001), but not the C(-9)G polymorphism (OR=1.28; 95% CI=0.48-3.38; <i>p</i>=0.621). Other findings in the study revealed that CC/CC haplotype is a protective factor for DR (OR=0.198; <i>p</i>=0.002), whereas CT/CC and CT/CG haplotypes as risk factors for DR with OR=15.58; <i>p</i>=0.002 and OR=2.29; <i>p</i>=0.005 respectively.</p><p><strong>Conclusion: </strong>It can be concluded that C(-104)T polymorphism in the regulatory region of Aldose Reductase (ALR2) gene was the risk factor for DR among T2DM patients in Bali, Indonesia. However, small sample size, systolic blood pressure, fasting blood glucose and 2-hours post-prandial blood glucose could affect our finding.</p>","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"12 ","pages":"281-288"},"PeriodicalIF":0.3,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36742323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Maximising Refractive Outcomes with an Extended Depth of Focus IOL. 扩大聚焦深度的人工晶状体的最大屈光效果。
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-09-28 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010273
Barry Power, Rory Murphy, Antonio Leccisotti, Tara Moore, William Power, Paul O'Brien
{"title":"Maximising Refractive Outcomes with an Extended Depth of Focus IOL.","authors":"Barry Power,&nbsp;Rory Murphy,&nbsp;Antonio Leccisotti,&nbsp;Tara Moore,&nbsp;William Power,&nbsp;Paul O'Brien","doi":"10.2174/1874364101812010273","DOIUrl":"https://doi.org/10.2174/1874364101812010273","url":null,"abstract":"<p><strong>Objective: </strong>To assess the impact of the magnitude of preoperative and postoperative corneal astigmatism on refractive outcomes in patients undergoing cataract surgery or lens exchange with an extended depth of focus intraocular lens. To compare visual outcomes of steep and temporal on-axis corneal incisions.</p><p><strong>Setting: </strong>Department of Ophthalmology, Blackrock Clinic, Dublin, Ireland.</p><p><strong>Design: </strong>Prospective cohort analysis.</p><p><strong>Methods: </strong>Fifty-three consecutive adult patients (94 eyes) undergoing routine phacoemulsification with Symfony IOL implantation were analysed. Exclusion criteria: targets for mini-monovision, incomplete data, other ocular pathology. Data were prospectively collected on pre- and postoperative refraction, keratometry, distance vision, near vision, surgical wound site and Surgically Induced Astigmatism (SIA).</p><p><strong>Results: </strong>The average postoperative monocular Uncorrected Distance and Near visual acuities (UDVA and UNVA) were 0.12 LogMAR (± 0.1) (6/7.5<sup>+1</sup>) and 0.34 LogMAR (± 0.09) respectively. The average binocular UDVA and UNVA were 0.05 (± 0.07) and 0.29 LogMAR (± 0.06) respectively. Low levels of preoperative corneal astigmatism (0-0.99 D) were associated with better LogMAR UDVA and UNVA when compared with higher levels (> 0.99 D): 0.11 (CI 0.103-0.107) <i>vs.</i> 0.206 (CI 0.122-0.290) (<i>p</i> =0.015, CI 95%) and 0.33 (CI 0.316 - 0.356) <i>vs.</i> 0.39 (CI 0.34-0.43) (<i>p</i> =0.034, CI 95%) respectively. When patients with steep on-axis corneal incisions were compared with temporal on-axis corneal incisions, no difference was detected in visual outcome or SIA.</p><p><strong>Conclusion: </strong>The Symfony IOL is an effective surgical means of addressing presbyopia and reducing postoperative spectacle dependence. We stress caution when offering potential spectacle independence for patients with over 1D of preoperative corneal astigmatism as these patients achieve statistically significantly inferior and less predictable visual results.</p>","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"12 ","pages":"273-280"},"PeriodicalIF":0.3,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874364101812010273","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36614306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Refractive Error among Male Primary School Students in Jazan, Saudi Arabia: Prevalence and Associated Factors. 沙特阿拉伯吉赞市男小学生屈光不正患病率及相关因素
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-09-28 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010264
Tariq Al Bahhawi, Anwar M Makeen, Hadi Hassan Daghreeri, Mohannad Faisal Tobaigy, Abdulrahman Mohammed Adawi, Faisal Mohammed Guhal, Murad Abdullah Akkur, Mohsen Jaber Alotayfi, Mutaz Mohammed Otayf, Meshal Salem Bajoned, Mohamed Salih Mahfouz
{"title":"Refractive Error among Male Primary School Students in Jazan, Saudi Arabia: Prevalence and Associated Factors.","authors":"Tariq Al Bahhawi,&nbsp;Anwar M Makeen,&nbsp;Hadi Hassan Daghreeri,&nbsp;Mohannad Faisal Tobaigy,&nbsp;Abdulrahman Mohammed Adawi,&nbsp;Faisal Mohammed Guhal,&nbsp;Murad Abdullah Akkur,&nbsp;Mohsen Jaber Alotayfi,&nbsp;Mutaz Mohammed Otayf,&nbsp;Meshal Salem Bajoned,&nbsp;Mohamed Salih Mahfouz","doi":"10.2174/1874364101812010264","DOIUrl":"https://doi.org/10.2174/1874364101812010264","url":null,"abstract":"<p><strong>Background: </strong>Refractive error is a common and serious eye disorder that affects more than 153 million people globally. The aim of this study was to estimate the prevalence and pattern of refractive error among male primary school children in Jazan region, Saudi Arabia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among a randomly selected group of 395 students (aged 6-14 years) in Jazan region, Southwest Saudi Arabia. An optometrist and medical students assessed the refraction error using an autorefractor, a Snellen E chart and retinoscopy.</p><p><strong>Results: </strong>The overall prevalence of uncorrected refractive error in either eye was, 22% higher among rural students. The most prevalent refractive error was hyperopia (32.2%) followed by myopic astigmatism (31%) then myopia (17.2%). Next were hyperopic astigmatism (16.1%) and mixed astigmatism (3.5%). The following variables were associated with a higher risk of refractive errors and myopia: living in rural areas, having parents with refractive errors, spending more time on electronic devices and shorter visual distances.</p><p><strong>Conclusion: </strong>Refractive error was highly prevalent among primary school children in Jazan, Saudi Arabia. The rural students were more affected by refractive errors, mainly hyperopia. The preschool vision test should be reconsidered, and a periodic vision examination should be applied to detect vision problems as early as possible.</p>","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"12 ","pages":"264-272"},"PeriodicalIF":0.3,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874364101812010264","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36614305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Outcomes of Wavefront-Optimized Laser-Assisted In-Situ Keratomileusis and Photorefractive Keratectomy for correction of Myopia and Myopic Astigmatism over One Year Follow-Up. 波前优化激光辅助原位角膜磨砂术及光屈光性角膜切除术治疗近视及近视散光1年随访结果。
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-09-26 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010256
Mohammad M Shehadeh, Mohammad T Akkawi, Ammar A Aghbar, Muna T Musmar, Malak N Khabbas, Marah F Kharouf, Liana Al-Labadi
{"title":"Outcomes of Wavefront-Optimized Laser-Assisted <i>In-Situ</i> Keratomileusis and Photorefractive Keratectomy for correction of Myopia and Myopic Astigmatism over One Year Follow-Up.","authors":"Mohammad M Shehadeh,&nbsp;Mohammad T Akkawi,&nbsp;Ammar A Aghbar,&nbsp;Muna T Musmar,&nbsp;Malak N Khabbas,&nbsp;Marah F Kharouf,&nbsp;Liana Al-Labadi","doi":"10.2174/1874364101812010256","DOIUrl":"https://doi.org/10.2174/1874364101812010256","url":null,"abstract":"<p><strong>Background: </strong>Laser corneal refractive surgery suits, technology and nomograms are improving with time. This may improve the refractive and visual outcomes of the patients.</p><p><strong>Objectives: </strong>To evaluate the safety, efficacy, stability, and predictability of wavefront-optimized photorefractive keratectomy and Laser-assisted <i>in-situ</i> keratomileusis in patients with myopia and myopic astigmatism over 1-year using WaveLight<sup>®</sup> EX500 Excimer Laser machine.</p><p><strong>Methods: </strong>In this prospective cohort study, refractive and visual outcomes in 596 eyes (365 patients), either having myopia or myopic astigmatism were assessed. Patients were divided into Two groups: 1) Patients who underwent PRK (53 eyes have myopia and 217 eyes have myopic astigmatism), 2) Patients who underwent LASIK (53 eyes have myopia and 273 eyes have myopic astigmatism).</p><p><strong>Results: </strong>At 12 months postoperatively 94.3% of the myopic patients reached their preoperative best corrected distance visual acuity at the final one year follow up visit post PRK and LASIK. In patients with myopic astigmatism who underwent LASIK and PRK, 95.2%, and 96.3% of the patients reached their preoperative best corrected distance visual acuity at the final one year follow up visit post LASIK and PRK, respectively. The efficacy and safety indices were 1.00 or more for all groups with no eye lost any line of best corrected distance visual acuity.</p><p><strong>Conclusion: </strong>Our study results confirm the excellent efficacy, safety, good predictability and stability of myopia / myopic astigmatism correction by either wavefront- optimized LASIK or PRK over 1-year follow-up without significant differences between them using the WaveLight<sup>®</sup> EX500 excimer laser system.</p>","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"12 ","pages":"256-263"},"PeriodicalIF":0.3,"publicationDate":"2018-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874364101812010256","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36553117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Clinical Characteristics, Treatment Outcomes and Predictive Factors in Optic Neuritis. 视神经炎的临床特点、治疗结果及预测因素。
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-08-31 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010247
Linda Hansapinyo, Chayanee Vivattanaseth
{"title":"Clinical Characteristics, Treatment Outcomes and Predictive Factors in Optic Neuritis.","authors":"Linda Hansapinyo,&nbsp;Chayanee Vivattanaseth","doi":"10.2174/1874364101812010247","DOIUrl":"https://doi.org/10.2174/1874364101812010247","url":null,"abstract":"<p><strong>Background: </strong>The causes, clinical presentations and treatment outcomes of optic neuritis are distinct among different populations. Early diagnosis based on clinical presentations plays an important role in treating optic neuritis patients.</p><p><strong>Objective: </strong>The study aimed to determine clinical characteristics, treatment outcomes and predictive factors of treatment outcomes in optic neuritis patients with and without demyelinating disease.</p><p><strong>Methods: </strong>A retrospective descriptive study of optic neuritis patients carried out between January 2009 and December 2016 was done. Univariate analysis and multivariate logistic regression analysis were used to evaluate the predictive factors of treatment outcomes.</p><p><strong>Results: </strong>Among 150 patients with optic neuritis, 58 patients were diagnosed with Neuromyelitis Optica Spectrum Disease (NMOSD), 23 patients were diagnosed with Multiple Sclerosis (MS) and 69 patients were idiopathic. The age at presentation in the NMOSD group was significantly younger than the MS group and the idiopathic group. The female:male ratio was significantly lower in the idiopathic group than in the NMOSD group. The initial Best Corrected Visual Activity (BCVA) of 20/20-20/60 (<i>p</i> = 0.001) and the idiopathic group (<i>p</i> =0.030) was associated with good visual outcomes. Initial BCVA of < 20/200 (<i>p</i> = 0.009) and the NMOSD group (<i>p</i> < 0.001) was associated with poor visual outcomes.</p><p><strong>Conclusion: </strong>NMOSD is a more common cause of optic neuritis than MS in Thai population. Female patients with poor initial VA, poor response to steroids treatment, and presenting recurrent attacks are highly suspicious for NMOSD. Optic neuritis without associated demyelinating disease has a better visual outcome and lower recurrence rate.</p>","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"12 ","pages":"247-255"},"PeriodicalIF":0.3,"publicationDate":"2018-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874364101812010247","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36523665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
A New User-Friendly and Affordable Method in Descemet Stripping Endothelial Keratoplasty. 一种用户友好且经济实惠的角膜剥离内皮移植术新方法。
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-08-29 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010242
Mohammad Soleimani, Seyed Ali Tabatabaei, Reza Mirshahi
{"title":"A New User-Friendly and Affordable Method in Descemet Stripping Endothelial Keratoplasty.","authors":"Mohammad Soleimani,&nbsp;Seyed Ali Tabatabaei,&nbsp;Reza Mirshahi","doi":"10.2174/1874364101812010242","DOIUrl":"https://doi.org/10.2174/1874364101812010242","url":null,"abstract":"<p><strong>Aims: </strong>To describe a new technique in Descemet Stripping Automated Endothelial Keratoplasty (DSAEK).</p><p><strong>Materials and methods: </strong>In this technique, we use easily available materials (mainly a Nelaton tube) to make an injector for loading DSAEK lenticule and also easily pulling it (using a gauge 23 needle) into the eye. In this paper, we report outcomes of this technique in four cases.</p><p><strong>Results: </strong>Using these available instruments could easily lead to a clear postoperative cornea. Mean Endothelial Cell Density (ECD) loss at sixth postoperative month was 26%.</p><p><strong>Conclusion: </strong>We proposed a novel effective user-friendly and affordable technique to perform DSAEK.</p>","PeriodicalId":512318,"journal":{"name":"The Open Ophthalmology Journal","volume":"12 ","pages":"242-246"},"PeriodicalIF":0.3,"publicationDate":"2018-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36476611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous Accelerated Corneal Crosslinking and Laser In situ Keratomileusis for the Treatment of High Myopia in Asian Eyes. 加速角膜交联联合激光原位角膜磨镶术治疗亚洲人高度近视。
IF 0.3
The Open Ophthalmology Journal Pub Date : 2018-08-27 eCollection Date: 2018-01-01 DOI: 10.2174/1874364101812010241
Jin Rong Low, Li Lim, Jane Chwee Wah Koh, Daniel Kai Peng Chua, Mohamad Rosman
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引用次数: 18
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