Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-04-01DOI: 10.1080/01652176.2024.2331530
Jue Gui, Md Abul Kalam Azad, Wenchao Lin, Chengwen Meng, Xin Hu, Yadong Cui, Wei Lan, Jianhua He, Xiangfeng Kong
{"title":"Chinese herb ultrafine powder supplementation improves egg nutritional value and quality in laying hens.","authors":"Jue Gui, Md Abul Kalam Azad, Wenchao Lin, Chengwen Meng, Xin Hu, Yadong Cui, Wei Lan, Jianhua He, Xiangfeng Kong","doi":"10.1080/01652176.2024.2331530","DOIUrl":"10.1080/01652176.2024.2331530","url":null,"abstract":"<p><p>This study evaluates the effects of dietary Chinese herb ultrafine powder (CHUP) supplementation in late-phase laying hens on the quality and nutritional values of eggs. A total of 576 Xinyang black-feather laying hens (300-day-old) were randomly allocated into eight groups for a 120-day feeding trial. Each group contained eight replicates with nine hens per replicate. The experimental groups included the control (basal diet) and different levels of CHUP groups (details in 'Materials and methods'). The results showed that the eggshell strength was increased (<i>p</i> < 0.05) in the L, LF, L-LF, L-T, and LF-T groups on day 60 of the trial. In addition, the plasma estradiol level in the L-LF, LF-T, and L-LF-T groups and unsaturated fatty acids concentrations in egg yolk of the CHUP groups (except LF-T group) were increased, whereas total cholesterol (T, L-LF, L-T, and L-LF-T groups) in egg yolk and the atherogenicity (T, L-T, and L-LF-T groups) and thrombogenicity (T, L-LF, L-T, and L-LF-T groups) indexes were decreased (<i>p</i> < 0.05) on day 60 of the trial compared with the control group. Moreover, bitter amino acids in egg albumen were decreased (<i>p</i> < 0.05) in the L-LF group on day 60 and the L-LF-T group on day 120 of the trial. Collectively, these findings indicate that dietary CHUP supplementation could improve eggshell quality and increase plasma reproductive hormone, fatty acid and amino acid composition, and nutritional values of eggs, especially L-LF and L-LF-T.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-17"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10986442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-04-01DOI: 10.1080/01652176.2024.2319830
Shabana Naz, Gulnaz Bibi, Rida Nadeem, Ibrahim A Alhidary, Sifa Dai, Muhammad Israr, Rifat Ullah Khan
{"title":"Evaluation of biological selenium nanoparticles on growth performance, histopathology of vital organs and genotoxicity in Japanese quails (<i>coturnix coturnix japonica)</i>.","authors":"Shabana Naz, Gulnaz Bibi, Rida Nadeem, Ibrahim A Alhidary, Sifa Dai, Muhammad Israr, Rifat Ullah Khan","doi":"10.1080/01652176.2024.2319830","DOIUrl":"10.1080/01652176.2024.2319830","url":null,"abstract":"<p><p>Research on the effects of selenium nanoparticles (Se-NPs), particularly in Japanese quails, is lacking, especially regarding the potential for DNA damage. Therefore, this study aimed to investigate the impact of administering 0.2 and 0.4 mg/kg of Se-NPs on the growth performance, DNA integrity, and histopathological alterations of the liver, lung, kidney, and heart in quails. A total of 480 one-day-old Japanese quails were divided into three experimental groups as follows: Group 1 served as the control and received only basic feed, while Group 2 and 3 received 0.2 mg/kg and 0.4 mg/kg of Se-NPs <i>via</i> oral gavage. Our results suggested that, birds fed with Se-NPs at both levels significantly (<i>p</i> < .01) reduced feed intake, however, weight gain was significantly (<i>p</i> < .01) increased in quails supplemented with 0.2 mg/kg. Similarly, feed conversion ratio (FCR) was significantly (<i>p</i> < .01) reduced in group supplemented with 0.2 mg/kg Se-NPs. White blood cells increased significantly (P0.01) in 0.4 mg/kg while haemoglobin and red cell distribution width decreased (<i>p</i> < .01) in the same group. Both treatment regimens resulted in DNA damage and histopathological alterations; however, the adverse effects were more prominent in the group receiving the higher dose of 0.4 mg/kg. These findings indicate that the lower dose of 0.2 mg/kg may have beneficial effects on growth. However, the higher dose of 0.4 mg/kg not only negatively impacts growth but also leads to histopathological alterations in major organs of the body and DNA damage as well.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-10"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10986439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-02-29DOI: 10.1080/01652176.2023.2300948
Abdul Hafeez, Said Shahid Ali, Junaid Akhtar, Shabana Naz, Abdulwahed Fahad Alrefaei, Mohammed Fahad Albeshr, Muhammad Israr, Rifat Ullah Khan
{"title":"Impact of coriander (<i>Coriandrum sativum</i>), garlic (<i>Allium sativum</i>), fenugreek (<i>Trigonella foenum-graecum</i>) on zootechnical performance, carcass quality, blood metabolites and nutrient digestibility in broilers chickens.","authors":"Abdul Hafeez, Said Shahid Ali, Junaid Akhtar, Shabana Naz, Abdulwahed Fahad Alrefaei, Mohammed Fahad Albeshr, Muhammad Israr, Rifat Ullah Khan","doi":"10.1080/01652176.2023.2300948","DOIUrl":"10.1080/01652176.2023.2300948","url":null,"abstract":"<p><p>The study investigated the impact of incorporating a specific herbal blend comprising coriander, garlic, and fenugreek (CGF) at various levels on the zootechnical performance, blood metabolites and nutrient digestibility in broiler chickens. The 42-day experiment involved 360 broilers (Cobb 500), organized into four distinct treatment groups. The dietary interventions included a control group consisting of a basal diet and the same diet was supplemented with CGF at rates of 1, 2, and 3%. Broilers receiving a 1% phytogenic mixture exhibited significantly increased live weight and carcass weight. Moreover, the digestibility of crude protein and crude fat significantly improved in broilers supplemented with a 1% phytogenic mixture. On the other hand, the digestibility of calcium and phosphorus showed a notable increase in broilers fed with a 3% phytogenic mixture. Regarding serum metabolites, the 1% phytogenic mixture group displayed significantly higher levels of high density lipoprotein and triglycerides. The supplementation of the broiler diet with a herbal mixture of coriander, fenugreek, and garlic at a 1% rate resulted in improved growth performance, carcass quality, nutrient digestion, and lipid profile.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-7"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-08-04DOI: 10.1080/01652176.2024.2387072
Francesca De Falco, Anna Cutarelli, Francesca Luisa Fedele, Cornel Catoi, Sante Roperto
{"title":"Molecular findings and virological assessment of bladder papillomavirus infection in cattle.","authors":"Francesca De Falco, Anna Cutarelli, Francesca Luisa Fedele, Cornel Catoi, Sante Roperto","doi":"10.1080/01652176.2024.2387072","DOIUrl":"10.1080/01652176.2024.2387072","url":null,"abstract":"<p><p>Bovine and ovine papillomaviruses (BPVs - OaPVs) are infectious agents that have an important role in bladder carcinogenesis of cattle. In an attempt to better understand territorial prevalence of papillomavirus genotypes and gain insights into their molecular pathway(s), a virological assessment of papillomavirus infection was performed on 52 bladder tumors in cattle using droplet digital polymerase chain reaction (ddPCR), an improved version of conventional PCR. ddPCR detected and quantified BPV DNA and mRNAs in all tumor samples, showing that these viruses play a determinant role in bovine bladder carcinogenesis. OaPV DNA and mRNA were detected and quantified in 45 bladder tumors. BPV14, BPV13, BPV2, OaPV2, OaPV1, and OaPV3 were the genotypes most closely related to bladder tumors. ddPCR quantified BPV1 and OaPV4 DNA and their transcripts less frequently. Western blot analysis revealed a significant overexpression of the phosphorylated platelet derived growth factor β receptor (PDGFβR) as well as the transcription factor E<sub>2</sub>F<sub>3</sub>, which modulate cell cycle progression in urothelial neoplasia. Furthermore, significant overexpression of calpain1, a Cys protease, was observed in bladder tumors related to BPVs alone and in BPV and OaPV coinfection. Calpain1 has been shown to play a role in producing free transcription factors of the E<sub>2</sub>F family, and molecular findings suggest that calpain family members work cooperatively to mutually regulate their protease activities in cattle bladder tumors. Altogether, these results showed territorial prevalence of BPV and OaPV genotypes and suggested that PDGFβR and the calpain system appeared to be molecular partners of both BPVs and OaPVs.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-7"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11299453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-05-06DOI: 10.1080/01652176.2024.2347928
Naod Thomas Masebo, Giovanna Marliani, Flavia Shannon Del Re, Laura Abram, Damiano Cavallini, Marco Di Pietro, Andrea Beltrame, Eliana Schiavon, Marilena Bolcato, Joaquin Hernandez Bermudez, Arcangelo Gentile, Joana G P Jacinto
{"title":"Evaluation of antimicrobial and non-steroidal anti-inflammatory treatments for BRD on health and welfare in fattening bulls: a cross-sectional study.","authors":"Naod Thomas Masebo, Giovanna Marliani, Flavia Shannon Del Re, Laura Abram, Damiano Cavallini, Marco Di Pietro, Andrea Beltrame, Eliana Schiavon, Marilena Bolcato, Joaquin Hernandez Bermudez, Arcangelo Gentile, Joana G P Jacinto","doi":"10.1080/01652176.2024.2347928","DOIUrl":"10.1080/01652176.2024.2347928","url":null,"abstract":"<p><p>Our study aimed to evaluate the effect of different treatments for BRD on health and welfare in fattening bulls. A total of 264 bulls were enrolled. Welfare was assessed on day 2 (T0) and day 15 (T1) after arrival. A decrease in the welfare level was observed from T0 to T1. All bulls were inspected clinically at T0 and T1 revealing an increase of skin lesions and lameness in T1. In both periods, a high incidence of respiratory disease was observed. A prevalence of 79.55% and 95.45% of <i>Mycoplasma bovis</i> using RT-PCR and culture at T0 and T1 respectively was observed. Blood samples were collected for haematology at T0 and T1. At T0, 36 animals were individually treated for BRD with an antimicrobial (IT), 54 received a metaphylactic treatment with tulathromycin (M), 150 received a metaphylactic treatment with tulathromycin plus a second antimicrobial (M + IT) whereas 24 were considered healthy and therefore not treated (NT). Additionally, 128 were treated with a non-steroid anti-inflammatory (NSAID). Neutrophils of M + IT were significantly higher than groups NT and M and the lymphocytes of M + IT were significantly lower than that of IT. White blood cells, neutrophils and N/L ratio of animals treated with an NSAID was significantly higher than that not treated. Lung inspection of 172 bulls at the abattoir indicated that 92.43% presented at least one lung lesion. A statistically significant effect of the NSAID treatment on the lung lesions was observed. Our findings indicate that BRD was a major welfare and health concern and evidence the difficulties of antimicrobial treatment of <i>M. bovis</i>.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-11"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11078067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-05-10DOI: 10.1080/01652176.2024.2349948
Eman A Mady, Haruna Osuga, Haruka Toyama, Hussein M El-Husseiny, Ryo Inoue, Harutaka Murase, Yuki Yamamoto, Kentaro Nagaoka
{"title":"Relationship between the components of mare breast milk and foal gut microbiome: shaping gut microbiome development after birth.","authors":"Eman A Mady, Haruna Osuga, Haruka Toyama, Hussein M El-Husseiny, Ryo Inoue, Harutaka Murase, Yuki Yamamoto, Kentaro Nagaoka","doi":"10.1080/01652176.2024.2349948","DOIUrl":"10.1080/01652176.2024.2349948","url":null,"abstract":"<p><p>The gut microbiota (GM) is essential for mammalian health. Although the association between infant GM and breast milk (BM) composition has been well established in humans, such a relationship has not been investigated in horses. Hence, this study was conducted to analyze the GM formation of foals during lactation and determine the presence of low-molecular-weight metabolites in mares' BM and their role in shaping foals' GM. The fecal and BM samples from six pairs of foals and mares were subjected to 16S ribosomal RNA metagenomic and metabolomic analyses, respectively. The composition of foal GM changed during lactation time; hierarchical cluster analysis divided the fetal GM into three groups corresponding to different time points in foal development. The level of most metabolites in milk decreased over time with increasing milk yield, while threonic acid and ascorbic acid increased. Further analyses revealed gut bacteria that correlated with changes in milk metabolites; for instance, there was a positive correlation between <i>Bacteroidaceae</i> in the foal's gut microbiota and serine/glycine in the mother's milk. These findings help improve the rearing environment of lactating horses and establish artificial feeding methods for foals.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-9"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11089936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140907657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-11-07DOI: 10.1080/01652176.2024.2421308
Diana Marteles, María Victoria Martínez, Antonio Fernández, Cristina Riera, Roser Fisa, Xavier Roca-Geronès, Sarah Chavez-Fisa, Sergio Castañeda, Juan David Ramírez, Janine Elizabeth Davis, Petra Sumova, Petr Volf, Maite Verde, Ana González, María Magdalena Alcover, Sergio Villanueva-Saz
{"title":"Assessment of the exposure to <i>Phlebotomus perniciosus</i> and the presence of anti-<i>Leishmania infantum</i> antibodies in stray cats in an endemic region of Spain, and their potential correlation with environmental factors.","authors":"Diana Marteles, María Victoria Martínez, Antonio Fernández, Cristina Riera, Roser Fisa, Xavier Roca-Geronès, Sarah Chavez-Fisa, Sergio Castañeda, Juan David Ramírez, Janine Elizabeth Davis, Petra Sumova, Petr Volf, Maite Verde, Ana González, María Magdalena Alcover, Sergio Villanueva-Saz","doi":"10.1080/01652176.2024.2421308","DOIUrl":"10.1080/01652176.2024.2421308","url":null,"abstract":"<p><p><i>Phlebotomus perniciosus</i> is a major vector of <i>Leishmania infantum</i> in the Mediterranean. While the seroprevalence of leishmaniosis in Spanish dogs and cats has been studied, data on the exposure of cats to <i>P. perniciosus</i> bites under natural conditions without repellents is limited. Stray cats could serve as sentinels for <i>L. infantum</i> and <i>P. perniciosus</i> exposure. This study analyzed sera from 204 apparently healthy stray cats, collected from January 2021 to January 2022, for antibodies against <i>P. perniciosus</i> saliva and <i>L. infantum</i> parasites. Anti-sand fly antibodies were detected in 40.69% of cats using an ELISA with the recombinant salivary protein SP03B of <i>P. perniciosus</i>. Seroprevalence of <i>L. infantum</i> infection was 23.52% by Western blot and 27.41% by ELISA, with an overall seroprevalence of 40.69% (95% CI 34.18-47.54%). This is the first assessment of antibody response to <i>P. perniciosus</i> saliva and <i>L. infantum</i> in naturally exposed stray cats in Spain. Further research is needed to examine the salivary antigens recognized by cats and to explore the relationship between <i>P. perniciosus</i> exposure and <i>L. infantum</i> infection severity in cats.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-8"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-07-31DOI: 10.1080/01652176.2024.2384910
Ming-Jen Kang, Pin-Chen Liu, Hock Gan Heng, Kuan-Sheng Chen
{"title":"Correlation between change in serum creatinine concentration and renal cortical anisotropic backscattering artifact in azotemic cats during hospitalization.","authors":"Ming-Jen Kang, Pin-Chen Liu, Hock Gan Heng, Kuan-Sheng Chen","doi":"10.1080/01652176.2024.2384910","DOIUrl":"10.1080/01652176.2024.2384910","url":null,"abstract":"<p><p>Information on the clinical outcomes of feline azotemia using ultrasound examinations is limited. This study aimed to understand the correlation between cortical anisotropy backscattering artifact (CABA) and serum creatinine (sCr) changes in feline azotemia after hospitalization and to investigate whether CABA is useful for predicting the clinical outcome of feline azotemia. Sixty-five hospitalized cats with azotemia, including 49 cats with moderate or severe azotemia (severe group) and 16 cats with mild azotemia (mild group). This retrospective study reviewed the CABA using ultrasound images of cats hospitalized with azotemia between 2016 and 2021. The correlation between CABA and the clinical outcomes of cats with azotemia was investigated using the chi-squared or Fisher's exact test, and the intra- and inter-observer agreements in CABA were assessed using McNemar's and Cohen's kappa tests. The presence of CABA was significantly positively correlated with the clinical outcomes of cats with azotemia only in the severe group (<i>p</i> = 0.0034, odds ratio = 8.57). There was no association between CABA and clinical outcomes in cats with mild azotemia (<i>p</i> = 0.75). CABA can be used for clinical outcome prediction in moderate and severe feline azotemia, with a sensitivity of 80.8% and a specificity of 73.9%. Also, satisfactory intra- and inter-observer agreements were revealed in the detection of CABA during ultrasound image review. Our study demonstrated that cats with moderate and severe azotemia with CABA observed during ultrasonography might have better clinical outcomes. These findings provide additional information on the prognosis and treatment of feline azotemia.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-8"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-08-29DOI: 10.1080/01652176.2024.2396577
Abdullah Mohammed, Musa Ahmed, Nasir Ibrahim
{"title":"The global seroprevalence of <i>Toxoplasma gondii</i> infection in workers occupationally exposed to animals (1972-2023): a systematic review and meta-analysis.","authors":"Abdullah Mohammed, Musa Ahmed, Nasir Ibrahim","doi":"10.1080/01652176.2024.2396577","DOIUrl":"10.1080/01652176.2024.2396577","url":null,"abstract":"<p><p><i>Toxoplasma gondii</i>, a ubiquitous zoonotic parasite infecting warm-blooded animals, poses a significant health threat to workers with occupational animal exposure (WOEA) due to their frequent contact with potential reservoirs. Existing data on <i>T. gondii</i> seroprevalence in the WOEA exhibits substantial global variation. This systematic review and meta-analysis, adhering to PRISMA guidelines, aimed to quantify the global seroprevalence of <i>T. gondii</i> infection among WOEA over the past five decades (1972-2023). We identified 66 eligible studies through a comprehensive search strategy encompassing English publications, with a total sample size of 15,279. A random-effects model with the Freeman-Tukey transformation in STATA v16.0 accounted for the high heterogeneity observed. We estimated the pooled global seroprevalence of <i>T. gondii</i> infection in WOEA at 41% (95% CI: 36-47%). Subgroup analyses revealed significant variations by gender: males (63%) vs. females (37%) (<i>p</i> < 0.05), occupation: non-livestock workers (54%), livestock workers (47%), slaughterhouse workers (44%), and veterinary personnel (27%) (<i>p</i> < 0.05). Geographic trends showed the highest prevalence in Africa (51%), followed by South America (49%), Europe (47%), Australia (43%), Asia (36%), and North America (23%; <i>p</i> < 0.05). Lower prevalence was observed in high-income (39%) and upper-middle-income (38%) countries compared to lower-middle-income (44%) and low-income (48%) countries (<i>p</i> < 0.05). This analysis underscores the high global seroprevalence of <i>T. gondii</i> in the WOEA, highlighting the need for targeted interventions in this high-risk population.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-18"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11363739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veterinary QuarterlyPub Date : 2024-12-01Epub Date: 2024-11-01DOI: 10.1080/01652176.2024.2419585
Giovanna P Vicente, Leonardo Della Salda, Ricardo F Strefezzi
{"title":"Beclin-1 and LC3B expression in canine mast cell tumours: an immuno-ultrastructural and immunohistochemical study of autophagy.","authors":"Giovanna P Vicente, Leonardo Della Salda, Ricardo F Strefezzi","doi":"10.1080/01652176.2024.2419585","DOIUrl":"10.1080/01652176.2024.2419585","url":null,"abstract":"<p><p>Mast cell tumours (MCTs) are common malignant neoplasms in dogs, for which prognosis and therapeutic decisions are based on histological features and proliferation markers. Autophagy is a cellular catabolic process responsible for degrading cytoplasmic components to maintain homeostasis, alterations in which are frequently linked to tumour growth and progression. This study was conducted to investigate the occurrence of autophagy in canine MCTs and to verify its value as a prognostic indicator for dogs with the disease. Beclin-1 and LC3B expressions were investigated using immunohistochemistry, and autophagy was ultrastructurally characterised. The autophagic phenomenon was successfully visualised in neoplastic mast cells under transmission electron and immunoelectron microscopy. MCTs from dogs that died due to the disease showed higher positivity for Beclin-1 and dogs with MCTs presenting a LC3B granular immunohistochemical pattern had a significantly shorter post-surgical survival. The occurrence of autophagy is an indicator of poor prognosis. Future studies are needed to elucidate the specific mechanisms and open new opportunities to treatments targeting this cancer cell advantage.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-15"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}