Trends in Cardiovascular Medicine最新文献

{"title":"Redefining care: The four pillars of women's cardiovascular programs.","authors":"Rachel M Bond","doi":"10.1016/j.tcm.2025.08.003","DOIUrl":"10.1016/j.tcm.2025.08.003","url":null,"abstract":"<p><p>Cardiovascular disease remains the leading cause of death among women in the United States, yet sex-specific disparities in diagnosis, treatment, and outcomes persist. Women's specialized cardiac programs have emerged to address these gaps through inclusive, patient-centered models of care. This article reviews the evolution, structure, and impact of these programs, which function as hubs for clinical care, education, advocacy, and research. Highlighted are best practices, measurable outcomes, and key challenges, offering recommendations for integrating gender-focused cardiovascular care across diverse healthcare settings.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence and extended reality in TAVR: current applications and challenges.","authors":"Ioannis Skalidis, Neila Sayah, Hakim Benamer, Nicolas Amabile, Pietro Laforgia, Stéphane Champagne, Thomas Hovasse, Jérôme Garot, Philippe Garot, Mariama Akodad","doi":"10.1016/j.tcm.2025.08.002","DOIUrl":"10.1016/j.tcm.2025.08.002","url":null,"abstract":"<p><p>Integration of AI and XR in TAVR is revolutionizing the management of severe aortic stenosis by enhancing diagnostic accuracy, risk stratification, and pre-procedural planning. Advanced algorithms now facilitate precise electrocardiographic, echocardiographic, and CT-based assessments that reduce observer variability and enable patient-specific risk prediction. Immersive XR technologies, including augmented, virtual, and mixed reality, improve spatial visualization of complex cardiac anatomy and support real-time procedural guidance. Despite these advancements, standardized protocols, regulatory frameworks, and ethical safeguards remain necessary for widespread clinical adoption.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of calcium and vitamin D supplementation on cardiovascular disease outcomes: A review of interventional studies.","authors":"Austin Ayer, Aldo Dominguez, Jose B Cruz Rodriguez","doi":"10.1016/j.tcm.2025.07.012","DOIUrl":"10.1016/j.tcm.2025.07.012","url":null,"abstract":"<p><p>We summarize the literature of randomized controlled trials and associated meta-analyses related to the effects of calcium and/or vitamin D supplementation on cardiovascular disease outcomes. Despite significant epidemiologic data associating abnormal calcium or vitamin D levels with cardiovascular disease risk, no consistent signal has emerged from the interventional literature for a causal relationship between supplementation of these micronutrients and improved cardiovascular outcomes. There is some evidence to support increased risk of coronary heart disease with calcium supplementation alone, and the effects of vitamin D supplementation on cardiovascular disease appear to be neutral. Overall, there is no evidence to support the routine use of calcium or vitamin D supplementation for the purposes of improving cardiovascular health.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Type 2 MI and the sex divide: Moving from awareness to action.","authors":"Melody Huang, Nicholas Phreaner","doi":"10.1016/j.tcm.2025.08.001","DOIUrl":"10.1016/j.tcm.2025.08.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Pulsed field ablation for SVT-A promising shift in the electrophysiology landscape.","authors":"Mohammad Al-Akchar","doi":"10.1016/j.tcm.2025.07.011","DOIUrl":"10.1016/j.tcm.2025.07.011","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"State-of-the-art review:Cardiac magnetic resonance imaging in primary cardiac tumors.","authors":"Tingting Zheng, Xinqiao Lian, Wenli Zhou, Li Li, Arlene Sirajuddin, Minjie Lu","doi":"10.1016/j.tcm.2025.07.006","DOIUrl":"10.1016/j.tcm.2025.07.006","url":null,"abstract":"<p><p>Cardiac tumors are very rare and their diagnosis and treatment remain challenging. Cardiac magnetic resonance imaging is considered the gold standard for noninvasive diagnosis because of its larger field of view, excellent tissue contrast, multiplanar imaging, and the unique ability to differentiate between different tissue features. CMR can effectively identify cardiac non-neoplastic and neoplastic mass, as well as benign and malignant tumors. This review summarizes the new technology of CMR, diagnosis, differential diagnosis and prognosis in cardiac primary tumor, especially the role of new technologies in cardiac primary tumors.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial commentary: Navigating the long-term landscape of mitral valve interventions in different mitral diseases.","authors":"Francesco Formica","doi":"10.1016/j.tcm.2025.07.010","DOIUrl":"10.1016/j.tcm.2025.07.010","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory cardiomyopathy: an update for clinicians.","authors":"Massimo Imazio","doi":"10.1016/j.tcm.2025.07.003","DOIUrl":"10.1016/j.tcm.2025.07.003","url":null,"abstract":"<p><p>Inflammatory cardiomyopathy (CMP) is a myocardial disorder characterized by persistent inflammation leading to ventricular dysfunction and remodeling, often evolving from acute myocarditis of infectious or immune-mediated origin. Its pathogenesis is multifactorial, involving viral triggers, dysregulated immune responses, and genetic predispositions, resulting in a broad clinical spectrum-from infarct-like presentations and arrhythmias to heart failure presentations. Diagnosis requires an integrated approach using multiple diagnostic tools, integrating clinical evaluation, ECG, biomarkers, multimodality imaging, including cardiac magnetic resonance (CMR), and endomyocardial biopsy (EMB), which remains the gold standard for identifying histologic subtypes and guiding immunosuppressive therapy. Genetic testing should be included in the integrated diagnosis due to its key role in diagnosis, risk stratification, treatment decisions, and outcome prediction in complicated recurrent cases, since pathogenic variants in genes (e.g. titin, DSP, FLNC) may predispose individuals to myocardial inflammation and recurrent injury. The prognosis is influenced by initial severity, fibrosis extent, and underlying etiology. Ongoing research into precision diagnostics and immunomodulatory treatments promises to improve outcomes in this heterogeneous and potentially reversible condition.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144719125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and outcomes of pulsed field ablation in the management of supraventricular arrhythmia: A systematic review.","authors":"Khalid Sawalha, Shayal Pundlik, Uneza Khawaja, Shaber Seraj, Mohamed Abdelazeem, Mohammed Abozenah, Fadi Chalhoub","doi":"10.1016/j.tcm.2025.07.008","DOIUrl":"10.1016/j.tcm.2025.07.008","url":null,"abstract":"<p><strong>Introduction: </strong>Pulsed field ablation (PFA) is an emerging non-thermal ablative technology that induces irreversible electroporation to selectively target cardiac tissue while minimizing damage to adjacent structures. While widely studied for atrial fibrillation, its role in managing supraventricular tachycardia (SVT) remains unclear. This systematic review aims to consolidate existing data on the safety and efficacy of PFA for SVT ablation.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted to identify studies reporting PFA outcomes in SVT. Inclusion criteria encompassed studies involving AVNRT, AVRT, and atrial tachycardia (AT). Data on procedural success, complications, and recurrence rates were extracted and analyzed. The review included 10 studies, comprising 3 case reports and 7 prospective studies, involving a total of 312 patients.</p><p><strong>Results: </strong>PFA demonstrated a high acute procedural success rate of 97.6 %. Success rates varied by SVT type: AVNRT (99.8 %), AVRT (98.7 %), and AT (96.1 %). Transient atrioventricular (AV) block, primarily during slow pathway ablation for AVNRT, occurred in 19.3 % of cases, with most resolving within 24 h. No permanent AV block or major procedural complications were reported. Recurrence rates were 9.6 % overall after six months, with AT exhibiting a higher recurrence rate of 21.4 %. Challenges with lesion durability, particularly in linear ablations, were noted, sometimes requiring adjunctive radiofrequency catheter ablation (RFCA). PFA's tissue selectivity proved beneficial in complex SVT cases near critical structures like the phrenic nerve and right atrial appendage, where RFCA posed higher complication risks.</p><p><strong>Conclusions: </strong>PFA shows promise as an effective and safe alternative to RFCA for SVT, particularly in challenging anatomical locations. Despite its high acute success rates and favorable safety profile, concerns about lesion durability and recurrence-especially in AT-necessitate further investigation. Larger, multicenter studies with standardized protocols are essential to optimize outcomes and clarify PFA's role in SVT ablation.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144719126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision management of coronary in-stent restenosis.","authors":"Travis M Wilson, Panagiotis M Sarris-Michopoulos, Riyan Siddiqui, Adeel Ahmed, Iqra Riaz, Giancarlo Licitra, Julia Ossi, Muzamil Khawaja, Alexander C Fanaroff, Akiko Maehara, Davide Capodanno, Chayakrit Krittanawong","doi":"10.1016/j.tcm.2025.07.009","DOIUrl":"10.1016/j.tcm.2025.07.009","url":null,"abstract":"<p><p>The advent of percutaneous coronary intervention (PCI) and intracoronary stent development marked a pivotal milestone in the management of acute coronary syndromes, significantly reducing morbidity and mortality worldwide. However, despite ongoing advancements in stent technology, treatment modalities, and diagnostic tools, in-stent restenosis (ISR) remains a prevalent and challenging clinical issue, contributing substantially to the burden of cardiovascular disease. This review provides a comprehensive background of ISR, including its associated risk factors, pathophysiology, and current management strategies. By addressing gaps in ISR management, this review critically evaluates existing approaches and explores potential directions for advancing the field of interventional cardiology. Additionally, supporting data for these strategies are examined, and a diagnostic and treatment algorithm is proposed to guide complex clinical decision-making.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}