Trends in Cardiovascular Medicine最新文献

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Enhanced cardiac PET: Illuminating the path to better CAD care-18F labeled myocardial perfusion PET. 增强心脏PET:照亮更好的CAD护理路径- 18f标记心肌灌注PET。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-14 DOI: 10.1016/j.tcm.2025.04.001
Anna Koulova, David H Hsi
{"title":"Enhanced cardiac PET: Illuminating the path to better CAD care-18F labeled myocardial perfusion PET.","authors":"Anna Koulova, David H Hsi","doi":"10.1016/j.tcm.2025.04.001","DOIUrl":"https://doi.org/10.1016/j.tcm.2025.04.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
18F labeled myocardial perfusion PET: New precision in cardiac imaging. 18F标记心肌灌注PET:新的心脏成像精度。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-14 DOI: 10.1016/j.tcm.2025.03.008
Takahiro Higuchi, Xinyu Chen, Maximilian Scheifele, Maximilian Fischer, Sebastian Clauss, Konrad Klimek, Rudolf A Werner
{"title":"<sup>18</sup>F labeled myocardial perfusion PET: New precision in cardiac imaging.","authors":"Takahiro Higuchi, Xinyu Chen, Maximilian Scheifele, Maximilian Fischer, Sebastian Clauss, Konrad Klimek, Rudolf A Werner","doi":"10.1016/j.tcm.2025.03.008","DOIUrl":"https://doi.org/10.1016/j.tcm.2025.03.008","url":null,"abstract":"<p><p>The rising global burden of coronary artery disease (CAD) underscores the need for advanced diagnostic tools. While single-photon emission computed tomography (SPECT) has been the cornerstone for myocardial perfusion imaging (MPI), it is increasingly being supplemented by positron emission tomography (PET) due to superior spatial resolution, sensitivity, and the ability to quantify myocardial blood flow. However, current PET tracers, including Rubidium-82, <sup>13</sup>N-Ammonia, and <sup>15</sup>O-Water, face limitations due to their short half-lives and logistical challenges. The advent of <sup>18</sup>F labeled PET tracers, such as Flurpiridaz F18, promises a new era in cardiac imaging by offering a longer half-life (110 minutes), compatibility with exercise stress testing, and high diagnostic accuracy. This review explores the current landscape of MPI, evaluates the clinical performance of novel <sup>18</sup>F tracers, and discusses their transformative potential in expanding access to PET imaging and improving CAD diagnostics.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transvenous leads' last stand: Non-transvenous defibrillators and a leadless future. 经静脉导线的最后一站:非经静脉除颤器和无导线的未来。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-07 DOI: 10.1016/j.tcm.2025.03.007
David J Sanders, Alexander Mazur
{"title":"Transvenous leads' last stand: Non-transvenous defibrillators and a leadless future.","authors":"David J Sanders, Alexander Mazur","doi":"10.1016/j.tcm.2025.03.007","DOIUrl":"https://doi.org/10.1016/j.tcm.2025.03.007","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invasive management of unroofed coronary sinus: A systematic review. 无顶冠状窦的侵入治疗:系统回顾。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-05 DOI: 10.1016/j.tcm.2025.03.006
Ashley Slingerland, Muhammad Moolla, Kevin John, Liz Dennett, Jeevan Nagendran, Anoop Mathew
{"title":"Invasive management of unroofed coronary sinus: A systematic review.","authors":"Ashley Slingerland, Muhammad Moolla, Kevin John, Liz Dennett, Jeevan Nagendran, Anoop Mathew","doi":"10.1016/j.tcm.2025.03.006","DOIUrl":"10.1016/j.tcm.2025.03.006","url":null,"abstract":"<p><p>Unroofed coronary sinus (UCS) is a rare congenital anomaly, constituting under 1 % of atrial septal defects. Caused by partial or complete deficiency of the coronary sinus roof, UCS is often difficult to diagnose. While surgery remains the standard treatment, transcatheter approaches are emerging. We conducted a systematic review to evaluate outcomes of surgical and transcatheter approaches to UCS repair. Studies from MEDLINE, Embase, SCOPUS, and Web of Science were screened and selected based on predefined criteria. We extracted data on patient demographics, operative techniques, associated defects, and outcomes. Thirteen studies involving 293 patients with UCS were included. Majority (66.4 %) were male, with a mean age of 17.5 ± 11.5 years. UCS type 1A, marked by the presence of a persistent left superior vena cava and absent coronary sinus, was the most common subtype (50.4 %). Surgical repair was performed in 95.2 % of patients, with intracardiac baffle (34.1 %) and patch repair (21.9 %) being the predominant techniques. The remaining 4.8 % of patients underwent transcatheter repair, typically using Amplatzer® Septal Occluder device, with no reported procedural complications. In-hospital mortality rate was 2.7 %, and 30-day mortality was 3.0 %. Postoperative complications were rare, including residual defects (0.42 %), atrial fibrillation (2.9 %), and complete heart block requiring pacemaker (1.2 %). There were no cases of ischemic stroke. Surgical repair of UCS is associated with low postoperative mortality and complication rates, affirming its status as the standard of care. Transcatheter techniques may be feasible for select patients, though further studies are needed to to assess long-term outcomes and optimize criteria for patient selection.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardio obstetrics: Bridging heart and pregnancy health 心血管产科:连接心脏和孕期健康的桥梁。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.005
Rachel L. Goldberg , Sindhu Prabakaran , Nandita S. Scott
{"title":"Cardio obstetrics: Bridging heart and pregnancy health","authors":"Rachel L. Goldberg ,&nbsp;Sindhu Prabakaran ,&nbsp;Nandita S. Scott","doi":"10.1016/j.tcm.2024.10.005","DOIUrl":"10.1016/j.tcm.2024.10.005","url":null,"abstract":"<div><div>Cardiovascular disease remains a major contributor to maternal morbidity and mortality in the United States. Cardio Obstetrics is a nascent field for which most cardiovascular clinicians have not received any formal training. This has resulted in knowledge and care gaps. In this review we provide principles to guide the care for the evaluation and management of pregnancy capable individuals, which should be considered the standard knowledge for all clinicians.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 166-174"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to diagnose and manage emergency medical conditions in patients on left ventricular assist device support: A clinician's field guide 如何诊断和处理病人在左心室辅助装置支持下的紧急医疗状况:临床医生的现场指南。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.11.004
Maya Guglin , Joshua R. Hirsch , Tanyanan Tanawuttiwat , Naveed Akhtar , Scott Silvestry , Onyedika J. Ilonze , R. Michelle Gehring , Emma J. Birks
{"title":"How to diagnose and manage emergency medical conditions in patients on left ventricular assist device support: A clinician's field guide","authors":"Maya Guglin ,&nbsp;Joshua R. Hirsch ,&nbsp;Tanyanan Tanawuttiwat ,&nbsp;Naveed Akhtar ,&nbsp;Scott Silvestry ,&nbsp;Onyedika J. Ilonze ,&nbsp;R. Michelle Gehring ,&nbsp;Emma J. Birks","doi":"10.1016/j.tcm.2024.11.004","DOIUrl":"10.1016/j.tcm.2024.11.004","url":null,"abstract":"<div><div>Left ventricular assist devices (LVADs) have revolutionized the treatment of advanced heart failure, providing mechanical circulatory support for patients awaiting heart transplantation or as destination therapy. However, patients on LVAD support are susceptible to a range of emergency medical conditions that require prompt recognition, intervention, and multidisciplinary management. This review paper aims to provide an algorithmic approach and a field guide on the diagnosis and management of emergency medical conditions in LVAD patients, including LVAD alarms, gastrointestinal bleeding, cerebrovascular accidents, pump thrombosis and obstruction, unresponsiveness, and electrical shock by the defibrillator. By understanding the mechanisms, clinical presentation, diagnostic evaluation, and therapeutic strategies associated with these conditions, healthcare providers can improve patient outcomes and optimize LVAD care.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 186-194"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Navigating the complexities of LVAD emergency management 驾驭 LVAD 紧急情况管理的复杂性。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.006
Aabha Divya
{"title":"Editorial commentary: Navigating the complexities of LVAD emergency management","authors":"Aabha Divya","doi":"10.1016/j.tcm.2024.12.006","DOIUrl":"10.1016/j.tcm.2024.12.006","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 195-196"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Moving the boundaries of the diagnosis of unexplained sudden cardiac arrest and sudden cardiac death in the young 移动年轻人不明原因心脏骤停和心脏性猝死诊断的边界。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.009
Matteo Vatta
{"title":"Editorial commentary: Moving the boundaries of the diagnosis of unexplained sudden cardiac arrest and sudden cardiac death in the young","authors":"Matteo Vatta","doi":"10.1016/j.tcm.2024.12.009","DOIUrl":"10.1016/j.tcm.2024.12.009","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 184-185"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Applying guidelines directed medical therapy for heart failure: The cardiologist hard job 应用指南指导心力衰竭的药物治疗:心脏病医生的艰巨任务
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.004
Gabriele Fragasso
{"title":"Editorial commentary: Applying guidelines directed medical therapy for heart failure: The cardiologist hard job","authors":"Gabriele Fragasso","doi":"10.1016/j.tcm.2024.10.004","DOIUrl":"10.1016/j.tcm.2024.10.004","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 151-153"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases 初级预防的个性化:探索冠状动脉钙和多基因风险评分在心血管疾病中的作用。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.003
Mario Mekhael , Ghassan Bidaoui , Austin Falloon , Amitabh C. Pandey
{"title":"Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases","authors":"Mario Mekhael ,&nbsp;Ghassan Bidaoui ,&nbsp;Austin Falloon ,&nbsp;Amitabh C. Pandey","doi":"10.1016/j.tcm.2024.10.003","DOIUrl":"10.1016/j.tcm.2024.10.003","url":null,"abstract":"<div><div>Personalized healthcare is becoming increasingly popular given the vast heterogeneity in disease manifestation between individuals. Many commonly encountered diseases within cardiology are multifactorial in nature and disease progression and response is often variable due to environmental and genetic factors influencing disease states. This makes accurate early identification and primary prevention difficult in certain populations, especially young patients with limited Atherosclerotic Cardiovascular Disease (ASCVD) risk factors. Newer strategies, such as coronary artery calcium (CAC) scans and polygenic risk scores (PRS), are being implemented to aid in the detection of subclinical disease and heritable risk, respectively. Data surrounding CAC scans have shown promising results in their ability to detect subclinical atherosclerosis and predict the risk of future coronary events, especially at the extremes; however, predictive variability exists among different patient populations, limiting the test's specificity. Furthermore, relying only on CAC scores and ASCVD risk scores may fail to identify a large group of patients needing primary prevention who lack subclinical disease and traditional risk factors, but harbor genetic variabilities strongly associated with certain cardiovascular diseases. PRS can overcome these limitations. These scores can be measured in individuals as early as birth to identify genetic variants placing them at elevated risk for developing cardiovascular disease, irrespective of their current cardiovascular health status. By applying PRS alongside CAC scores, previously overlooked patient populations can be identified and begin primary prevention strategies early to achieve optimal outcomes. In this review, we expand on the current knowledge surrounding CAC scores and PRS and highlight the future possibilities of these technologies for preventive cardiology.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 154-163"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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