Belinda Gray, Michael J Ackerman, Mark S Link, Rachel Lampert
{"title":"Vigorous exercise and sports participation in individuals with hypertrophic cardiomyopathy.","authors":"Belinda Gray, Michael J Ackerman, Mark S Link, Rachel Lampert","doi":"10.1016/j.tcm.2024.09.004","DOIUrl":"10.1016/j.tcm.2024.09.004","url":null,"abstract":"<p><p>Historically, individuals with HCM have been restricted from vigorous competitive sports due to concerns for risk of sudden death. More recently, prospective data are emerging that individuals with HCM who participate in vigorous sports do not have increased arrhythmic risk compared to the less active, and series of athletes with HCM continuing to compete, while small, have not shown high risk. Guidelines are evolving, and while differences exist, all now recommend an individualized approach and shared decision-making for athletes with HCM wishing to return to play.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Graziano, Alessandro Zorzi, Alberto Cipriani, Barbara Bauce, Ilaria Rigato, Martina Perazzolo Marra, Hajnalka Vago, Bela Merkely, Kalliopi Pilichou, Cristina Basso, Domenico Corrado
{"title":"Contemporary diagnostic approach to arrhythmogenic cardiomyopathy: The three-step work-up.","authors":"Francesca Graziano, Alessandro Zorzi, Alberto Cipriani, Barbara Bauce, Ilaria Rigato, Martina Perazzolo Marra, Hajnalka Vago, Bela Merkely, Kalliopi Pilichou, Cristina Basso, Domenico Corrado","doi":"10.1016/j.tcm.2024.09.002","DOIUrl":"10.1016/j.tcm.2024.09.002","url":null,"abstract":"<p><p>Arrhythmogenic Cardiomyopathy (ACM) is a cardiac disorder characterized by non-ischemic myocardial scarring, which may lead to ventricular electrical instability and systolic dysfunction. Diagnosing ACM is challenging as there is no single gold-standard test and a combination of criteria is required. The first diagnostic criteria were established in 1994 and revised in 2010, focusing primarily on right ventricular involvement. However, in 2019, an international expert report identified limitations of previous diagnostic scoring and developed the 2020 Padua criteria with also included criteria for diagnosis of left ventricular variants and introduced cardiac magnetic resonance tissue characterization findings for detection of left ventricular myocardial scar. These criteria were further refined and published in 2023 as the European Task Force criteria, gaining international recognition. This review provides an overview of the 20 years of progresses on the disease diagnostic from the original 1994 criteria to the most recent 2023 European criteria, highlighting the evolution into our understanding of the pathobiology and morpho-functional features of the disease.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Approach to the office patient with apparent resistant or refractory hypertension: Is there a role for renal denervation?","authors":"Andrew Foy","doi":"10.1016/j.tcm.2024.09.003","DOIUrl":"https://doi.org/10.1016/j.tcm.2024.09.003","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Redwane Rakza, Pierre Groussin, Karim Benali, Nathalie Behar, Philippe Mabo, Dominique Pavin, Christophe Leclercq, Jackson J Liang, Raphaël P Martins
{"title":"Responses to the letter by Feka et al. regarding oral hydroquinidine as an alternative to intravenous quinidine: Quinidine for ventricular arrhythmias.","authors":"Redwane Rakza, Pierre Groussin, Karim Benali, Nathalie Behar, Philippe Mabo, Dominique Pavin, Christophe Leclercq, Jackson J Liang, Raphaël P Martins","doi":"10.1016/j.tcm.2024.09.001","DOIUrl":"https://doi.org/10.1016/j.tcm.2024.09.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muzamil Khawaja, Michael Britt, Affan Rizwan, Jocelyn Abraham, Taylor Nguyen, Uzair Munaf, Muhammad Asad Khan, Hassaan Arshad, Muhamed Munye, Noah Newman, Alfonso Ielasi, Simon Eccleshall, Vassilios S Vassiliou, Ioannis Merinopoulos, Bernardo Cortese, Chayakrit Krittanawong
{"title":"Coronary drug-coated balloons: A comprehensive review of clinical applications and controversies.","authors":"Muzamil Khawaja, Michael Britt, Affan Rizwan, Jocelyn Abraham, Taylor Nguyen, Uzair Munaf, Muhammad Asad Khan, Hassaan Arshad, Muhamed Munye, Noah Newman, Alfonso Ielasi, Simon Eccleshall, Vassilios S Vassiliou, Ioannis Merinopoulos, Bernardo Cortese, Chayakrit Krittanawong","doi":"10.1016/j.tcm.2024.08.006","DOIUrl":"10.1016/j.tcm.2024.08.006","url":null,"abstract":"<p><p>Drug-coated balloons have emerged as a promising therapeutic option in the treatment of cardiovascular disease. This review article provides an overview of the concept of drug-coated balloons and their clinical applications in both de novo and treated coronary artery disease. A summary of key clinical trials and registry studies evaluating drug-coated balloons is presented for reference. Overall, this article aims to provide clinicians and researchers with a comprehensive understanding of the current state of drug-coated balloon technology and its implications in clinical practice.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial commentary: is oral hydroquinidine a real alternative to intravenous quinidine for intubated patients in intensive care unit?","authors":"Alma Feka, Marianne Cumin, Farshid Sadeghipour","doi":"10.1016/j.tcm.2024.08.004","DOIUrl":"https://doi.org/10.1016/j.tcm.2024.08.004","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aneel S Maini, Mansi Maini, Tayo Addo, Vivek Koshti, Thomas Koshy, James A de Lemos, Angela Price, Dharam J Kumbhani
{"title":"The Current State and Future of Renal Denervation: A Review.","authors":"Aneel S Maini, Mansi Maini, Tayo Addo, Vivek Koshti, Thomas Koshy, James A de Lemos, Angela Price, Dharam J Kumbhani","doi":"10.1016/j.tcm.2024.08.005","DOIUrl":"https://doi.org/10.1016/j.tcm.2024.08.005","url":null,"abstract":"<p><p>Renal denervation as an option for difficult to treat hypertension has been a concept for several decades, with recent U.S. FDA approval of new, minimally invasive devices. However, while renal denervation has the potential to improve hypertension management, several challenges require consideration prior to widespread adoption. The effect relative to sham control is modest, and generally similar to addition of a single blood pressure lowering medication. It is possible that with additional technique refinement greater effects may be possible. Key factors to consider beyond the direction, strengths, and limitations of the renal denervation technologies themselves, are an understanding of patient groups that derive greatest benefit and phenotypes or biomarkers that predict greater response. This review provides an update on these challenges in addition to the current state and future of renal denervation within the context of hypertension management and treatment.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is it finally prime time for artificial intelligence to improve the care of patients with hypertrophic cardiomyopathy?","authors":"Richard T Carrick, Ethan J Rowin","doi":"10.1016/j.tcm.2024.08.003","DOIUrl":"10.1016/j.tcm.2024.08.003","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142074451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronary plaque characterization and cardiovascular risk using radiomics and artificial intelligence.","authors":"Ciprian Ionita, John M Canty","doi":"10.1016/j.tcm.2024.07.005","DOIUrl":"10.1016/j.tcm.2024.07.005","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leopoldo Ordine, Grazia Canciello, Felice Borrelli, Raffaella Lombardi, Salvatore Di Napoli, Roberto Polizzi, Cristina Falcone, Brigida Napolitano, Lorenzo Moscano, Alessandra Spinelli, Elio Masciari, Giovanni Esposito, Maria-Angela Losi
{"title":"Artificial intelligence-driven electrocardiography: Innovations in hypertrophic cardiomyopathy management.","authors":"Leopoldo Ordine, Grazia Canciello, Felice Borrelli, Raffaella Lombardi, Salvatore Di Napoli, Roberto Polizzi, Cristina Falcone, Brigida Napolitano, Lorenzo Moscano, Alessandra Spinelli, Elio Masciari, Giovanni Esposito, Maria-Angela Losi","doi":"10.1016/j.tcm.2024.08.002","DOIUrl":"10.1016/j.tcm.2024.08.002","url":null,"abstract":"<p><p>Hypertrophic Cardiomyopathy (HCM) presents a complex diagnostic and prognostic challenge due to its heterogeneous phenotype and clinical course. Artificial Intelligence (AI) and Machine Learning (ML) techniques hold promise in transforming the role of Electrocardiography (ECG) in HCM diagnosis, prognosis, and management. AI, including Deep Learning (DL), enables computers to learn patterns from data, allowing for the development of models capable of analyzing ECG signals. DL models, such as convolutional neural networks, have shown promise in accurately identifying HCM-related abnormalities in ECGs, surpassing traditional diagnostic methods. In diagnosing HCM, ML models have demonstrated high accuracy in distinguishing between HCM and other cardiac conditions, even in cases with normal ECG findings. Additionally, AI models have enhanced risk assessment by predicting arrhythmic events leading to sudden cardiac death and identifying patients at risk for atrial fibrillation and heart failure. These models incorporate clinical and imaging data, offering a comprehensive evaluation of patient risk profiles. Challenges remain, including the need for larger and more diverse datasets to improve model generalizability and address imbalances inherent in rare event prediction. Nevertheless, AI-driven approaches have the potential to revolutionize HCM management by providing timely and accurate diagnoses, prognoses, and personalized treatment strategies based on individual patient risk profiles. This review explores the current landscape of AI applications in ECG analysis for HCM, focusing on advancements in AI methodologies and their specific implementation in HCM care.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}