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Atrial fibrillation burden and management in cardiomyopathies: Current evidence and unmet needs.
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-10 DOI: 10.1016/j.tcm.2025.01.007
Alexios S Antonopoulos, Alexandros Kasiakogias, Alexandrina Kouroutzoglou, Maria Touloupaki, Alexandros Briasoulis, Efstathios Papatheodorou, Angelos G Rigopoulos, Dimitra Antonakaki, Aggeliki Laina, Konstantinos Tsioufis, Charalambos Vlachopoulos, George Lazaros
{"title":"Atrial fibrillation burden and management in cardiomyopathies: Current evidence and unmet needs.","authors":"Alexios S Antonopoulos, Alexandros Kasiakogias, Alexandrina Kouroutzoglou, Maria Touloupaki, Alexandros Briasoulis, Efstathios Papatheodorou, Angelos G Rigopoulos, Dimitra Antonakaki, Aggeliki Laina, Konstantinos Tsioufis, Charalambos Vlachopoulos, George Lazaros","doi":"10.1016/j.tcm.2025.01.007","DOIUrl":"10.1016/j.tcm.2025.01.007","url":null,"abstract":"<p><p>Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in patients with cardiomyopathies and its clinical management presents a significant challenge. The prevalence of AF varies among cardiomyopathies, with hypertrophic (HCM) and dilated cardiomyopathy (DCM) associated with higher rates of AF. Presence of AF portends increased risk for thromboembolism, heart failure, and cardiovascular morbidity and mortality in patients with cardiomyopathy. The complex genetic substrate in DCM and non-dilated left ventricular cardiomyopathy (NDLVC) contribute to the heterogeneity of AF burden and its sequelae among cardiomyopathy genotypes, necessitating genotype-tailored approach in AF screening and management. Given the lack of validation of traditional risk scores for AF in cardiomyopathies, current clinical recommendations emphasize the importance of comprehensive risk stratification for AF, monitoring for AF, and early initiation of oral anticoagulation for brief AF episodes in specific cardiomyopathy subtypes such as hypertrophic or amyloid cardiomyopathy. AF management includes antiarrhythmic drugs, interventional therapies such as catheter ablation, mitral valve replacement when necessary, and lifestyle modifications to attenuate AF burden and improve quality of life. This review summarizes the current knowledge on the clinical significance, prognostic implications, and treatment of AF among different cardiomyopathy subtypes. We underscore the paradigm shift in AF management advocating for an individualized, subtype-specific, and genotype-aware approach to AF in cardiomyopathies, which is instrumental in improving prognosis and patient-centric care.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac implantable electronic device infection: Prevention is better than cure ….
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-10 DOI: 10.1016/j.tcm.2025.02.002
Antoine Da Costa, Karim Benali
{"title":"Cardiac implantable electronic device infection: Prevention is better than cure ….","authors":"Antoine Da Costa, Karim Benali","doi":"10.1016/j.tcm.2025.02.002","DOIUrl":"10.1016/j.tcm.2025.02.002","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quinidine for ventricular arrhythmias: A comprehensive review 奎尼丁治疗室性心律失常：全面回顾
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.07.003
Redwane Rakza , Pierre Groussin , Karim Benali , Nathalie Behar , Philippe Mabo , Dominique Pavin , Christophe Leclercq , Jackson J. Liang , Raphaël P. Martins
{"title":"Quinidine for ventricular arrhythmias: A comprehensive review","authors":"Redwane Rakza ,&nbsp;Pierre Groussin ,&nbsp;Karim Benali ,&nbsp;Nathalie Behar ,&nbsp;Philippe Mabo ,&nbsp;Dominique Pavin ,&nbsp;Christophe Leclercq ,&nbsp;Jackson J. Liang ,&nbsp;Raphaël P. Martins","doi":"10.1016/j.tcm.2024.07.003","DOIUrl":"10.1016/j.tcm.2024.07.003","url":null,"abstract":"<div><div>Quinidine, the first antiarrhythmic drug, was widely used during the 20th century. Multiple studies have been conducted to provide insights into the pharmacokinetics and pleiotropic effects of Class Ia antiarrhythmic drugs. However, safety concerns and the emergence of new drugs led to a decline in their use during the 1990s.</div><div>Despite this, recent studies have reignited the interest in quinidine, particularly for ventricular arrhythmias, where other antiarrhythmics have failed. In conditions such as Brugada syndrome, idiopathic ventricular fibrillation, early repolarization syndrome, short QT syndrome, and electrical storms, quinidine remains a valuable asset. Starting from the European and American recommendations, this comprehensive review aimed to explore the various indications for quinidine and the studies that support its use. We also discuss the potential future of quinidine, including the necessary research to optimize its use and patient selection. Additionally, it addresses the imperative task of mitigating the iatrogenic burden associated with quinidine usage and confronts the challenge of ensuring drug accessibility.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 73-81"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary drug-coated balloons: A comprehensive review of clinical applications and controversies 冠状动脉药物涂层球囊：临床应用与争议综述》。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.08.006
Muzamil Khawaja , Michael Britt , Affan Rizwan , Jocelyn Abraham , Taylor Nguyen , Uzair Munaf , Muhammad Asad Khan , Hassaan Arshad , Muhamed Munye , Noah Newman , Alfonso Ielasi , Simon Eccleshall , Vassilios S. Vassiliou , Ioannis Merinopoulos , Bernardo Cortese , Chayakrit Krittanawong
{"title":"Coronary drug-coated balloons: A comprehensive review of clinical applications and controversies","authors":"Muzamil Khawaja ,&nbsp;Michael Britt ,&nbsp;Affan Rizwan ,&nbsp;Jocelyn Abraham ,&nbsp;Taylor Nguyen ,&nbsp;Uzair Munaf ,&nbsp;Muhammad Asad Khan ,&nbsp;Hassaan Arshad ,&nbsp;Muhamed Munye ,&nbsp;Noah Newman ,&nbsp;Alfonso Ielasi ,&nbsp;Simon Eccleshall ,&nbsp;Vassilios S. Vassiliou ,&nbsp;Ioannis Merinopoulos ,&nbsp;Bernardo Cortese ,&nbsp;Chayakrit Krittanawong","doi":"10.1016/j.tcm.2024.08.006","DOIUrl":"10.1016/j.tcm.2024.08.006","url":null,"abstract":"<div><div>Drug-coated balloons have emerged as a promising therapeutic option in the treatment of cardiovascular disease. This review article provides an overview of the concept of drug-coated balloons and their clinical applications in both de novo and treated coronary artery disease. A summary of key clinical trials and registry studies evaluating drug-coated balloons is presented for reference. Overall, this article aims to provide clinicians and researchers with a comprehensive understanding of the current state of drug-coated balloon technology and its implications in clinical practice.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 84-95"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Responses to the letter by Feka et al. regarding oral hydroquinidine as an alternative to intravenous quinidine 对 Feka 等人关于用口服氢奎尼丁替代静脉注射奎尼丁的信件的回复：奎尼丁治疗室性心律失常。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.09.001
Redwane Rakza , Pierre Groussin , Karim Benali , Nathalie Behar , Philippe Mabo , Dominique Pavin , Christophe Leclercq , Jackson J. Liang , Raphaël P. Martins
{"title":"Responses to the letter by Feka et al. regarding oral hydroquinidine as an alternative to intravenous quinidine","authors":"Redwane Rakza ,&nbsp;Pierre Groussin ,&nbsp;Karim Benali ,&nbsp;Nathalie Behar ,&nbsp;Philippe Mabo ,&nbsp;Dominique Pavin ,&nbsp;Christophe Leclercq ,&nbsp;Jackson J. Liang ,&nbsp;Raphaël P. Martins","doi":"10.1016/j.tcm.2024.09.001","DOIUrl":"10.1016/j.tcm.2024.09.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Page 139"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: “Three steps to ACM diagnosis – is it that easy?” 社论评论："诊断 ACM 的三个步骤--有那么容易吗？
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.10.001
Priya Bhardwaj , Stine B. Jacobsen , Jacob Tfelt-Hansen
{"title":"Editorial commentary: “Three steps to ACM diagnosis – is it that easy?”","authors":"Priya Bhardwaj ,&nbsp;Stine B. Jacobsen ,&nbsp;Jacob Tfelt-Hansen","doi":"10.1016/j.tcm.2024.10.001","DOIUrl":"10.1016/j.tcm.2024.10.001","url":null,"abstract":"<div><div>Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disease which predisposes to ventricular arrhythmias and sudden cardiac death. Since the introduction of the first diagnostic criteria in 1994, which focused exclusively on right ventricular involvement, diagnostic guidelines have evolved significantly over the past 30 years to encompass the full complexity of the ACM phenotype. In this issue of Trends in Cardiovascular Medicine, Graziano and colleagues review the advancements in ACM diagnostics which emphasizes a comprehensive evaluation of morpho-functional, structural, electrical, and genetic characteristics. The review outlines a three-step clinical approach for diagnosing ACM that involves assessing left and/or right ventricular involvement, identifying the specific ACM subtype, and determining its underlying etiology. This highlights the importance of interdisciplinary teamwork when approaching the complexities of diagnosing ACM and managing the family at risk.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 114-115"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Approach to the office patient with apparent resistant or refractory hypertension: Is there a role for renal denervation? 如何诊治明显耐药或难治性高血压患者？肾脏去神经支配有作用吗？
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.09.003
Andrew Foy
{"title":"Editorial commentary: Approach to the office patient with apparent resistant or refractory hypertension: Is there a role for renal denervation?","authors":"Andrew Foy","doi":"10.1016/j.tcm.2024.09.003","DOIUrl":"10.1016/j.tcm.2024.09.003","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 105-106"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Is it finally prime time for artificial intelligence to improve the care of patients with hypertrophic cardiomyopathy? 人工智能改善肥厚型心肌病患者护理的黄金时期终于到来了吗？
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.08.003
Richard T. Carrick , Ethan J. Rowin
{"title":"Editorial commentary: Is it finally prime time for artificial intelligence to improve the care of patients with hypertrophic cardiomyopathy?","authors":"Richard T. Carrick ,&nbsp;Ethan J. Rowin","doi":"10.1016/j.tcm.2024.08.003","DOIUrl":"10.1016/j.tcm.2024.08.003","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 135-136"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142074451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vigorous exercise and sports participation in individuals with hypertrophic cardiomyopathy 肥厚型心肌病患者的剧烈运动和体育锻炼。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.09.004
Belinda Gray , Michael J. Ackerman , Mark S Link , Rachel Lampert
{"title":"Vigorous exercise and sports participation in individuals with hypertrophic cardiomyopathy","authors":"Belinda Gray ,&nbsp;Michael J. Ackerman ,&nbsp;Mark S Link ,&nbsp;Rachel Lampert","doi":"10.1016/j.tcm.2024.09.004","DOIUrl":"10.1016/j.tcm.2024.09.004","url":null,"abstract":"<div><div>Historically, individuals with HCM have been restricted from vigorous competitive sports due to concerns for risk of sudden death. More recently, prospective data are emerging that individuals with HCM who participate in vigorous sports do not have increased arrhythmic risk compared to the less active, and series of athletes with HCM continuing to compete, while small, have not shown high risk. Guidelines are evolving, and while differences exist, all now recommend an individualized approach and shared decision-making for athletes with HCM wishing to return to play.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 116-123"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Exercise recommendations in hypertrophic cardiomyopathy shouldn't end at the recommendation 肥厚性心肌病的运动建议不应止于此。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2025-02-01 DOI: 10.1016/j.tcm.2024.12.001
André La Gerche
{"title":"Editorial commentary: Exercise recommendations in hypertrophic cardiomyopathy shouldn't end at the recommendation","authors":"André La Gerche","doi":"10.1016/j.tcm.2024.12.001","DOIUrl":"10.1016/j.tcm.2024.12.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 2","pages":"Pages 124-125"},"PeriodicalIF":7.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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