Trends in Cardiovascular Medicine最新文献

Invasive Management of Unroofed Coronary Sinus: A Systematic Review.

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-05 DOI: 10.1016/j.tcm.2025.03.006

Ashley Slingerland, Muhammad Moolla, Kevin John, Liz Dennett, Jeevan Nagendran, Anoop Mathew

{"title":"Invasive Management of Unroofed Coronary Sinus: A Systematic Review.","authors":"Ashley Slingerland, Muhammad Moolla, Kevin John, Liz Dennett, Jeevan Nagendran, Anoop Mathew","doi":"10.1016/j.tcm.2025.03.006","DOIUrl":"https://doi.org/10.1016/j.tcm.2025.03.006","url":null,"abstract":"<p><p>Unroofed coronary sinus (UCS) is a rare congenital anomaly, constituting under 1% of atrial septal defects. Caused by partial or complete deficiency of the coronary sinus roof, UCS is often difficult to diagnose. While surgery remains the standard treatment, transcatheter approaches are emerging. We conducted a systematic review to evaluate outcomes of surgical and transcatheter approaches to UCS repair. Studies from MEDLINE, Embase, SCOPUS, and Web of Science were screened and selected based on predefined criteria. We extracted data on patient demographics, operative techniques, associated defects, and outcomes. Thirteen studies involving 293 patients with UCS were included. Majority (66.4%) were male, with a mean age of 17.5 ± 11.5 years. UCS type 1A, marked by the presence of a persistent left superior vena cava and absent coronary sinus, was the most common subtype (50.4%). Surgery occurred in 95.2% of patients, with intracardiac baffle (34.1%) and patch repair (21.9%) being the predominant techniques. The remaining 4.8% of patients underwent transcatheter repair, typically using the Amplatzer ® Septal Occluder device, with no reported procedural complications. In-hospital mortality rate was 2.7%, and 30-day mortality was 3.0%. Postoperative complications were rare, including residual defects (0.42%), atrial fibrillation (2.9%), and complete heart block requiring pacemaker (1.2%). There were no cases of ischemic stroke. Surgical repair of UCS demonstrates low postoperative mortality and complication rates, affirming its status as the standard of care. Transcatheter techniques may be feasible for select patients, though further studies are needed to evaluate long-term outcomes and refine patient selection criteria.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardio obstetrics: Bridging heart and pregnancy health 心血管产科：连接心脏和孕期健康的桥梁。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.005

Rachel L. Goldberg , Sindhu Prabakaran , Nandita S. Scott

引用次数: 0

How to diagnose and manage emergency medical conditions in patients on left ventricular assist device support: A clinician's field guide 如何诊断和处理病人在左心室辅助装置支持下的紧急医疗状况：临床医生的现场指南。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.11.004

Maya Guglin , Joshua R. Hirsch , Tanyanan Tanawuttiwat , Naveed Akhtar , Scott Silvestry , Onyedika J. Ilonze , R. Michelle Gehring , Emma J. Birks

引用次数: 0

Editorial commentary: Navigating the complexities of LVAD emergency management 驾驭 LVAD 紧急情况管理的复杂性。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.006

Aabha Divya

引用次数: 0

Editorial commentary: Moving the boundaries of the diagnosis of unexplained sudden cardiac arrest and sudden cardiac death in the young 移动年轻人不明原因心脏骤停和心脏性猝死诊断的边界。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.009

Matteo Vatta

引用次数: 0

Editorial commentary: Applying guidelines directed medical therapy for heart failure: The cardiologist hard job 应用指南指导心力衰竭的药物治疗：心脏病医生的艰巨任务

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.004

Gabriele Fragasso

引用次数: 0

Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases 初级预防的个性化：探索冠状动脉钙和多基因风险评分在心血管疾病中的作用。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.003

Mario Mekhael , Ghassan Bidaoui , Austin Falloon , Amitabh C. Pandey

{"title":"Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases","authors":"Mario Mekhael , Ghassan Bidaoui , Austin Falloon , Amitabh C. Pandey","doi":"10.1016/j.tcm.2024.10.003","DOIUrl":"10.1016/j.tcm.2024.10.003","url":null,"abstract":"<div><div>Personalized healthcare is becoming increasingly popular given the vast heterogeneity in disease manifestation between individuals. Many commonly encountered diseases within cardiology are multifactorial in nature and disease progression and response is often variable due to environmental and genetic factors influencing disease states. This makes accurate early identification and primary prevention difficult in certain populations, especially young patients with limited Atherosclerotic Cardiovascular Disease (ASCVD) risk factors. Newer strategies, such as coronary artery calcium (CAC) scans and polygenic risk scores (PRS), are being implemented to aid in the detection of subclinical disease and heritable risk, respectively. Data surrounding CAC scans have shown promising results in their ability to detect subclinical atherosclerosis and predict the risk of future coronary events, especially at the extremes; however, predictive variability exists among different patient populations, limiting the test's specificity. Furthermore, relying only on CAC scores and ASCVD risk scores may fail to identify a large group of patients needing primary prevention who lack subclinical disease and traditional risk factors, but harbor genetic variabilities strongly associated with certain cardiovascular diseases. PRS can overcome these limitations. These scores can be measured in individuals as early as birth to identify genetic variants placing them at elevated risk for developing cardiovascular disease, irrespective of their current cardiovascular health status. By applying PRS alongside CAC scores, previously overlooked patient populations can be identified and begin primary prevention strategies early to achieve optimal outcomes. In this review, we expand on the current knowledge surrounding CAC scores and PRS and highlight the future possibilities of these technologies for preventive cardiology.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 154-163"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial commentary: Takotsubo syndrome: Be happy, then worry? Takotsubo综合症：先开心后担心？

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.012

J D Horowitz , A M Kucia , T H Nguyen

引用次数: 0

Guidelines for treating heart failure 心力衰竭治疗指南。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.002

Michelle M. Kittleson

引用次数: 0

Editorial commentary: Polygenic risk and coronary artery calcium score: Joining forces in preventive cardiology 编辑评论：多基因风险与冠状动脉钙化评分：预防性心脏病学中的强强联手。