Cardiac neuromodulation for ventricular arrhythmias: Current state and future perspectives. A comprehensive review.

IF 7.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Pierre Groussin, Donovan Decaudin, Melvyn Dezecot, Thomas Marc, Nathalie Behar, Dominique Pavin, Christophe Leclercq, Philippe Mabo, Karim Benali, RaphaëlP Martins
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引用次数: 0

Abstract

Electrical storm represents an urgent challenge in electrophysiology. Despite the use of antiarrhythmic medications and catheter ablation, refractory ventricular arrhythmias may persist, prompting the use of neuromodulation. This approach has evolved over the years, facing initial challenges owing to the intricacies of the autonomic nervous system. Animal studies have significantly enhanced our understanding of this system, paving the way for human studies on sympathetic modulation, which gained momentum in the early 2000s and expanded notably in cardiology in the 2010s. Presently, a variety of techniques coexist and offer diverse alternatives. Additionally, there are promising avenues for development that are primarily explored in animal models. This review aims to shed light on the diverse approaches currently available in this field.

室性心律失常的心脏神经调节:现状和未来展望。全面审查。
电风暴是电生理学的一个紧迫挑战。尽管使用抗心律失常药物和导管消融,难治性室性心律失常可能持续存在,促使使用神经调节。这种方法已经发展了多年,由于自主神经系统的复杂性,面临着最初的挑战。动物研究大大增强了我们对这一系统的理解,为人类交感调节研究铺平了道路,这一研究在21世纪初获得了发展势头,并在2010年代在心脏病学领域得到了显著扩展。目前,多种技术并存,提供了多种选择。此外,主要在动物模型中探索了有希望的发展途径。这篇综述旨在阐明目前在这一领域可用的各种方法。
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来源期刊
Trends in Cardiovascular Medicine
Trends in Cardiovascular Medicine 医学-心血管系统
CiteScore
18.70
自引率
2.20%
发文量
143
审稿时长
21 days
期刊介绍: Trends in Cardiovascular Medicine delivers comprehensive, state-of-the-art reviews of scientific advancements in cardiovascular medicine, penned and scrutinized by internationally renowned experts. The articles provide authoritative insights into various topics, encompassing basic mechanisms, diagnosis, treatment, and prognosis of heart and blood vessel disorders, catering to clinicians and basic scientists alike. The journal covers a wide spectrum of cardiology, offering profound insights into aspects ranging from arrhythmias to vasculopathies.
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