{"title":"Beyond samplism: Rethinking the field in exposure science","authors":"Sebastián Ureta","doi":"10.1177/03063127241288581","DOIUrl":"https://doi.org/10.1177/03063127241288581","url":null,"abstract":"Given the many forms of environmental pollution that have accompanied the global spread of industrial capitalism, there is an urgent need to carry out extensive assessments of the potential toxicity of many compounds on human and nonhuman populations. However, the scientific procedures developed to carry out such assessments present several critical shortcomings that greatly diminish their capacity to protect populations at risk. Through an ethnographic analysis of two field campaigns centered on the assessment of polluted sites in northern Chile, this article will reveal that these campaigns are embedded in what we can call samplism. Contrary to approaches that see fieldwork as generative spaces for knowledge creation, samplism radically simplifies the field into a neutral space for the collection of singular and well-defined lab-bound samples. However, samplism entails that multiple field phenomena relevant for assessing pollution levels are left completely unaccounted for, which greatly diminishes exposure science’s overall capacity to help improve the lives of those in need. Thus, exposure science urgently needs todevelop more capacious forms of engagement with the field, an ecological fieldwork that truly represents the complexity of forces and processes behind contemporary processes of pollution and damage.","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":"104 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Making citizens, procedures, and outcomes: Theorizing politics in a co-productionist idiom.","authors":"Hilton R Simmet","doi":"10.1177/03063127241269804","DOIUrl":"https://doi.org/10.1177/03063127241269804","url":null,"abstract":"The literature engaging political theory in STS often puts forward a deficit model view of STS, in which homegrown STS ideas about politics, such as co-production, are either treated as having an insufficient account of the political or not read as political theory at all. This article challenges the deficit discourse by reading co-production as a full-blown political theory in its own right, in particular by showing how it investigates normative questions of 'the good' that are central to any theorization of politics. Where political theory often concerns itself with the construction and application of universal political ideals-such as of the good citizen, legitimate procedures or smart outcomes-co-production looks at empirical sites where citizens, procedures, and outcomes articulate understandings of the good held by political actors in situ. By looking at the making of citizens, procedures, and outcomes in practice, we can better understand co-production as political theory. In particular, co-production elaborates on how the making of citizens, procedures, and outcomes constitute (and are constituted by) ideal normative positions, including: authoritative views about what citizens may claim to know, culturally-situated understandings of procedural legitimacy, and political values and ideologies embedded in seemingly 'objective' measurements of outcomes.","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":"33 1","pages":"3063127241269804"},"PeriodicalIF":3.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142436373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The techno-politics of computing the mind: Opening the black box of digital psychiatry.","authors":"Katerina Sideri,Niels van Dijk","doi":"10.1177/03063127241273067","DOIUrl":"https://doi.org/10.1177/03063127241273067","url":null,"abstract":"Psychiatry has recently witnessed the launch of digital phenotyping as a new research agenda. According to digital phenotyping's hypothesis, data about a patient's daily behavior can be continuously collected through wearable monitoring devices and used to build software that would send warnings of mental relapse or would tailor treatment choices. The research is exploratory, and the claims upon which it is based are contentious. Drawing on interviews, we followed a research team that aspired to build a digital system that could send such warnings to patients with mental health disorders like depression and epilepsy. This enabled us to learn how a new instrument to measure mental function becomes constructed and what translations take place in this process. Here we pay particular attention to the role of patients as research collaborators. We observed the frictions and debates in the research team between different mental health knowledge regimes, seeing them before they were black-boxed and lost from sight. We aimed to understand how actors anticipate software and data analytics to function alongside physicians and patients, as well as how different accounts reconstitute the 'mental', 'therapy', or the 'social' itself. We discuss several 'dissociations' that occur along the research trajectory regarding: less motivated and underrepresented patients, the role of clinical knowledge derived from patient self-reporting, and the social, political, and economic aspects of a patient's life affecting mental health. In this sense, we want to open the black box of this new behavioral technoscience.","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":"17 1","pages":"3063127241273067"},"PeriodicalIF":3.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142436374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melanie Jeske, Aliya Saperstein, Sandra Soo-Jin Lee, Janet K Shim
{"title":"Marginalized measures: The harmonization of diversity in precision medicine research.","authors":"Melanie Jeske, Aliya Saperstein, Sandra Soo-Jin Lee, Janet K Shim","doi":"10.1177/03063127241288498","DOIUrl":"https://doi.org/10.1177/03063127241288498","url":null,"abstract":"<p><p>The production of large, shareable datasets is increasingly prioritized for a wide range of research purposes. In biomedicine, especially in the United States, calls to enhance representation of historically underrepresented populations in databases that integrate genomic, health history, demographic and lifestyle data have also increased in order to support the goals of precision medicine. Understanding the assumptions and values that shape the design of such datasets and the practices through which they are constructed are a pressing area of social inquiry. We examine how diversity is conceptualized in U.S. precision medicine research initiatives, specifically attending to how measures of diversity, including race, ethnicity, and medically underserved status, are constructed and harmonized to build commensurate datasets. In three case studies, we show how symbolic embrace of both diversity and harmonization efforts can compromise the utility of diversity data. Although big data and diverse population representation are heralded as the keys to unlocking the promises of precision medicine research, these cases reveal core tensions between what kinds of data are seen as central to 'the science' and which are marginalized.</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"3063127241288498"},"PeriodicalIF":2.9,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Categorical misalignment: Making autism(s) in big data biobanking.","authors":"Kathryne Metcalf","doi":"10.1177/03063127241288223","DOIUrl":"https://doi.org/10.1177/03063127241288223","url":null,"abstract":"<p><p>The opaque relationship between biology and behavior is an intractable problem for psychiatry, and it increasingly challenges longstanding diagnostic categorizations. While various big data sciences have been repeatedly deployed as potential solutions, they have so far complicated more than they have managed to disentangle. Attending to <i>categorical misalignment</i>, this article proposes one reason why this is the case: Datasets have to instantiate clinical categories in order to make biological sense of them, and they do so in different ways. Here, I use mixed methods to examine the role of the reuse of big data in recent genomic research on autism spectrum disorder (ASD). I show how divergent regimes of psychiatric categorization are innately encoded within commonly used datasets from MSSNG and 23andMe, contributing to a rippling disjuncture in the accounts of autism that this body of research has produced. Beyond the specific complications this dynamic introduces for the category of autism, this paper argues for the necessity of critical attention to the role of dataset reuse and recombination across human genomics and beyond.</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"3063127241288223"},"PeriodicalIF":2.9,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Indigenous DNA as a metaphor: Nation-building and scientific debates on the rediscovery of Taiwanese ancestry.","authors":"Yu-Yueh Tsai","doi":"10.1177/03063127241226869","DOIUrl":"10.1177/03063127241226869","url":null,"abstract":"<p><p>In this paper, I investigate the co-production of genetic research and national politics in post-martial law Taiwan. This entails analyzing two co-produced phenomena: the nationalization of biomedicine-in which the national discourse over racial/ethnic categories and ancestral origin increasingly shapes scientists' biomedical research; and the biomedicalization of the nation-in which people in public discourse increasingly use biomedical categories in characterizing national differences and identities. I analyze how the production and representation of scientific knowledge of the ancestral origins and genetic make-up of Taiwan have been embedded in Taiwanese politics. This includes the emergence of a new categorization into four great ethnic groups, multiculturalism, and the assertion of a distinct Taiwanese national identity, particularly in response to the People's Republic of China's claims of common ancestry. I also examine how the scientific findings produced in the lab have spilled out into both Taiwan and China through journals, media, history textbooks, and public disputes since the 1990s and brought about significant social impact.</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"777-802"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140195033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The de-perimeterisation of information security: The Jericho Forum, zero trust, and narrativity.","authors":"Matt Spencer, Daniele Pizio","doi":"10.1177/03063127231221107","DOIUrl":"10.1177/03063127231221107","url":null,"abstract":"<p><p>This article analyses the transformation of information security induced by the Jericho Forum, a group of security professionals who argued for a new 'de-perimeterised' security model. Having focused on defensive perimeters around networks, early 2000s information security faced a growing set of pressures: the maintainability of firewalls given increasing traffic volume and variety, the vulnerability of interior network domains, and the need to cope with and enable new working arrangements and ways of doing business. De-perimeterisation was a radical rethinking of the nature of security and created the conditions for the rise of 'Zero Trust' architectures. This shift has radical implications for the architectures of digital infrastructures that undergird many aspects of contemporary life, the risks to which people and societies are exposed, and the nature of work and business in a digital economy. We develop a semiotic analysis of the Jericho Forum's interventions. Using insights from material semiotics, security theory and the theory of narrativity, we argue that de-perimeterisation can be understood as a shift in security logic, or, a shift in how security can (be made to) make sense. We examine a cluster of images used by the Jericho Forum, and analyse how they challenged the coherence of perimeter-based thinking and provided the materials for constructing a new model. We argue that a focus on the narrative dimension of security provides a window into fundamental semantic transformations, reciprocal historical relations between semantics and technical change, the <i>agencement</i> of security technologies, and determinations of value (what is worth securing).</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"655-677"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Law's artefacts: Personal rapid transit and public narratives of hitchhiking and crime.","authors":"Simon A Cole, Alyse Bertenthal","doi":"10.1177/03063127241229071","DOIUrl":"10.1177/03063127241229071","url":null,"abstract":"<p><p>The West Virginia University (WVU) Personal Rapid Transit (PRT) system was built between 1971 and 1975 in Morgantown, West Virginia to be a prototype transportation system of the future. Envisioned as a hybrid of public and automotive transportation, the fully automated cars deliver passengers directly to their destinations without stopping at intervening stations. The PRT concept may be familiar to STS scholars through Latour's study of Aramis, a PRT in Paris that was never completed. This article recounts a history with the opposite ending: the successful realization of a PRT in West Virginia. Our account supplements existing ones, which explain the construction of the WVUPRT primarily as the product of geography and politics. While not denying these factors, we carve out an explanatory role for another influence: a public narrative about the dangers of hitchhiking and crimes that might ensue from that practice. In weaving together that narrative with the history of the WVUPRT, we show how public narratives of crime authorize technological infrastructure.</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"749-776"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experimenting with care and cod: On document-practices, versions of care and fish as the new experimental animal.","authors":"Tone Druglitrø, Kristin Asdal","doi":"10.1177/03063127231223904","DOIUrl":"10.1177/03063127231223904","url":null,"abstract":"<p><p>A key ambition in care studies has been to study care in practice and <i>as</i> practice. By turning towards practices, care studies has rendered visible and acknowledged important work that is not captured through looking at formal procedures or official and written materials, such as policy documents and medical protocols. In this literature, document materials and the written have often been seen as unable to demonstrate and address the 'specificities of care' (Mol et al., 2010, p. 9). We challenge this view by showing how pragmatically-oriented approaches can be extended to the procedural and formalized aspects of care practices. We draw upon fieldwork in the life sciences-comparative immunology-investigated through experiments on Atlantic cod (<i>Gadus Morhua</i>). How to care for fish is a contested domain; many uncertainties exist around how to care for fish so that legal requirements are met. We ask: How are existing legal and ethical principles and procedures put to work in cod immunology and animal research? By what document-practices and document-tools is care for cod in research negotiated and settled? How does the cod stand out as an object of care in the life sciences? Our article answers these questions by empirically teasing out how scientists navigate the terrain and arguing for the importance of bringing the document-based realities of animal research into analysis. We do this by delineating three different <i>versions</i> of care: procedural care, skilled care, and dispassionate care.</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"706-727"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139567606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The stuff of memories: Planning hindsight in animal cryobanks.","authors":"Veit Braun","doi":"10.1177/03063127241252081","DOIUrl":"10.1177/03063127241252081","url":null,"abstract":"<p><p>Biobanks are becoming ubiquitous infrastructures in zoology and other non-human life sciences. They promise to store frozen research samples for the long term for future use. That use remains speculative but nevertheless needs to be anticipated. Following the establishment of a physical and digital infrastructure for frozen samples in an animal biobanking project, this article explores how the future is anticipated to remember the past, and how frozen objects are shaped accordingly. Situating the biobank between mundane freezing routines in a research lab and the 'dry' and 'wet' collections of natural history museums, I argue that frozen research objects need to be conserved in two separate ways. The unavailability of cryo-objects in cold storage forces researchers to store materials independently of metadata, while retaining a link between them that allows for their reunion after thawing. The result is a split object, leading a double life at sub-zero and room temperature, linked only through the surface of special plastic containers. Following the making of such split objects, this article offers an elaboration of Radin's 'planned hindsight' as well as a reflection on the universality and particularity of biobanks as standardized scientific memory.</p>","PeriodicalId":51152,"journal":{"name":"Social Studies of Science","volume":" ","pages":"728-748"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}