Neurocirugia最新文献

{"title":"Luxación atlantoaxial infrecuente secundaria a os odontoideo: estudio comparativo de variantes ortópicas y distópicas con dos casos representativos","authors":"Tong Yi ,&nbsp;Chongxi Xu ,&nbsp;Jinmei Li ,&nbsp;Junpeng Ma","doi":"10.1016/j.neucir.2025.500726","DOIUrl":"10.1016/j.neucir.2025.500726","url":null,"abstract":"<div><div>Atlantoaxial dislocation often results in upper cervical spinal cord compression, which may lead to significant neurological impairment. Among these, os odontoideum (OO) is a rare anomaly where the odontoid is replaced by a separate ossicle. Case one describes a 36-year-old male with dystopic OO presented a 4-month history of progressive incomplete quadriparesis. Radiological evaluation confirmed the presence of atlantoaxial dislocation associated with basilar invagination and OO, demonstrating an ossified structure with functional fusion between the free odontoid segment and the basion. Case two involves a 56-year-old female with orthotopic OO manifesting as cervical pain and arm weakness. Imaging studies revealed OO with anterior atlantoaxial dislocation. Dynamic radiographs demonstrated synchronous movement of the free odontoid ossicle with the anterior arch of C1 during flexion-extension. This study compares the clinical manifestations, radiographic features, treatment approaches, and outcomes between orthotopic and dystopic OO variants in patients, providing clinically relevant insights for management decisions.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500726"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacto de la enfermedad renal crónica en los resultados posoperatorios tras una craneotomía por hemorragia subaracnoidea aneurismática","authors":"Anmol Warman ,&nbsp;Renxi Li ,&nbsp;Luke M. Tomasovic ,&nbsp;Jeremy R. Ellis ,&nbsp;Eron J. Powell","doi":"10.1016/j.neucir.2025.500728","DOIUrl":"10.1016/j.neucir.2025.500728","url":null,"abstract":"<div><h3>Purpose</h3><div>Aneurysmal subarachnoid hemorrhage is an urgent manner in which blood accumulates in the subarachnoid region. Presence of chronic kidney disease (CKD) is often a predictor of adverse outcomes perioperatively. Patients with CKD may have different perioperative outcomes during surgery for aneurysmal subarachnoid hemorrhage compared to patients without CKD, and we sought to retrospectively examine the effect of CKD on perioperative outcomes in aSAH patients receiving surgery.</div></div><div><h3>Methods</h3><div>Patients undergoing craniotomy for aneurysmal subarachnoid hemorrhage were analyzed using the ACS-NSQIP database from 2005 to 2021. Patients with CKD were defined based on estimated glomerular filtration rate (eGFR) &lt;60<!--> <!-->mL/min. 30-Day postoperative outcomes were compared between the two groups and included death, cardiac complications, renal complications, sepsis, pulmonary complications, return to the operating room (OR), and operation time greater than 4<!--> <!-->h, among other variables.</div></div><div><h3>Results</h3><div>There were 122 CKD patients and 1456 non-CKD aSAH patients who underwent craniotomy identified. Compared to non-CKD patients, CKD patients had increased risk of mortality (30.33% vs. 12.84%, aOR 1.862, p<!--> <!-->=<!--> <!-->0.0097), renal complications (4.92% vs. 0.82%, aOR 3.911, p<!--> <!-->=<!--> <!-->0.0208), and bleeding perioperatively (31.97% vs. 14.56%, aOR 2.369, p<!--> <!-->&lt;<!--> <!-->0.0001).</div></div><div><h3>Conclusion</h3><div>This study demonstrated that CKD patients with aneurysmal subarachnoid hemorrhage receiving craniotomy have increased risk of death, renal complications, and bleeding perioperatively.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500728"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liberación del nervio pudendo masculino asistida por laparoscopia y monitorización neurofisiológica intraoperatoria","authors":"Claudia Fernandes ,&nbsp;Vanessa Viegas ,&nbsp;Alberto Artiles Medina ,&nbsp;Carlos Martins Silva ,&nbsp;Luis San José ,&nbsp;Luis López-Fando Lavalle","doi":"10.1016/j.neucir.2025.500714","DOIUrl":"10.1016/j.neucir.2025.500714","url":null,"abstract":"<div><h3>Introduction</h3><div>Pudendal nerve entrapment (PNE) is rare, and mostly affects women, with men accounting for only 1/3 of cases. The European guidelines advocate surgical decompression in select PNE cases. We aim to evaluate surgical outcomes in a group of male patients diagnosed with PNE who underwent laparoscopic decompression surgery supported by intraoperative neurophysiological monitoring (pIOM).</div></div><div><h3>Material and methods</h3><div>This retrospective and multicentric study included 138 patients with suspected PNE syndrome. The diagnosis of PNE was established based on neurophysiological tests and response to pudendal nerve block. Patients who experienced symptom relief following the nerve block underwent laparoscopic pudendal nerve decompression surgery, with pIOM utilized during the procedure. Symptom progression was tracked over a 12-month follow-up period.</div></div><div><h3>Results</h3><div>A total of 84 (60%) were diagnosed with PNE. Of these, 20 (24%) were male, with 14 (70%) receiving pudendal nerve infiltration. Six men (46%) later underwent laparoscopic pudendal nerve decompression surgery with pIOM. At the 12-month follow-up, five patients (83%) reported significant pain reduction, while one (17%) noted no improvement. Visual Analog Scale ranged between 2 and 5. Bladder dysfunction resolved in 2 of the 3. Two patients ceased all medications by the 12-month mark. In terms of satisfaction, four patients expressed complete satisfaction, one reported partial satisfaction, and one did not provide feedback.</div></div><div><h3>Conclusion</h3><div>Laparoscopic PNE decompression surgery, combined with pIOM is an effective intervention for male PNE patients with significant pain relief and enhanced quality of life. Further research is needed to validate these results and refine the criteria for patient selection.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500714"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor glioneuronal mixoide con mutación PDGFRA p.K385: hallazgos radiológicos de 2 casos","authors":"Anrong Zeng ,&nbsp;Xiaorui Su ,&nbsp;Wei Hu ,&nbsp;Qiang Yue","doi":"10.1016/j.neucir.2025.500725","DOIUrl":"10.1016/j.neucir.2025.500725","url":null,"abstract":"<div><div>Myxoid glioneuronal tumor represents a newly recognized entity in the 2021 World Health Organization classification of central nervous system tumors. As one of the 14 defined neuronal and glioneuronal tumors, it is molecularly characterized by PDGFRA p.K385 mutation. In this paper, we illustrate computed tomography, conventional and functional magnetic resonance imaging, and positron emission tomography-computed tomography imaging features of 2 myxoid glioneuronal tumor cases, introducing novel imaging characteristics.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500725"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mieloma múltiple simulando meningioma del surco olfatorio: presentación de caso y revisión de la literatura","authors":"Dilia Judith Mosquera Jiménez ,&nbsp;Leandro Carballo ,&nbsp;Matías Baldoncini ,&nbsp;Gustavo Sevlever ,&nbsp;Mickaela Echavarría Demichelis","doi":"10.1016/j.neucir.2025.500731","DOIUrl":"10.1016/j.neucir.2025.500731","url":null,"abstract":"<div><div>Central nervous system involvement by multiple myeloma is extremely rare and is diagnosed in less than 1% of cases. Differential diagnosis includes lymphomas, metastases, sarcomas, osteochondromas, hemangiopericytomas or meningiomas. We report a 46-year-old female with a history of multiple myeloma in apparent remission after autologous bone marrow transplantation, who consulted for a palpable mass in the frontal region associated with holocranial headache and decreased visual acuity of two months of evolution with imaging studies compatible with olfactory sulcus meningioma.</div><div>A craniotomy and total resection of the lesion by bicoronal approach was performed and histological sections showed a neoplastic proliferation consisting of cells with a spherical nucleus and lateralized eosinophilic cytoplasm. Lesion compatible with involvement of the central nervous system by multiple myeloma. This case highlights the diagnostic challenge due to radiologic similarity with other tumors, especially meningiomas, and emphasizes including myeloma in differential diagnoses.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500731"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mecanismo de presión hidrostática y eficacia quirúrgica en los quistes de Tarlov","authors":"Jingyi Xie ,&nbsp;Shaoqi Zhang ,&nbsp;Songquan Wang ,&nbsp;Laizhao Chen","doi":"10.1016/j.neucir.2025.500733","DOIUrl":"10.1016/j.neucir.2025.500733","url":null,"abstract":"<div><h3>Background</h3><div>Tarlov cysts (TCs) are commonly found sacral perineural cysts. Symptomatic TCs are rare, and there is no consensus on optimal treatment. The pathophysiological mechanism of TCs remains unclear. The aim of this study is to investigate the effects of surgical intervention on symptomatic TCs and the development mechanism of TCs.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed the clinical data of 26 patients with symptomatic TCs who underwent surgical treatment in our department between November 2016 and June 2019. Intraoperative manometry was performed in 10 of these patients. Pain relief and clinical outcomes were evaluated statistically.</div></div><div><h3>Results</h3><div>Postoperative symptoms improved in 25 patients (96.2%), while one patient (3.8%) showed no improvement. No wound infections or new complications were observed. Patients were followed for 5-49<!--> <!-->months (mean: 28.04<!--> <!-->±<!--> <!-->12.57 months). There were statistically significant decreases (<em>P</em> <!-->&lt;<!--> <!-->.05) in the M-JOA low back pain scores from preoperative (26.32<!--> <!-->±<!--> <!-->1.75) to postoperative (14.92<!--> <!-->±<!--> <!-->5.95) values, as well as a significant improvement (<em>P</em> <!-->&lt;<!--> <!-->.05) in the NRS pain scores from preoperative (2.02<!--> <!-->±<!--> <!-->1.46) to postoperative (6.23<!--> <!-->±<!--> <!-->1.20). Preoperative intracapsular pressure ranged from 3.1 to 12.4<!--> <!-->mmHg across different positions. postoperative sacral canal pressure ranged from 0.1 to 0.8<!--> <!-->mmHg in various positions.</div></div><div><h3>Conclusion</h3><div>Cyst excision and perineurium reconstruction under a microscope is an effective and safe method for treating sacral radicular cysts.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500733"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oclusión de la arteria principal en aneurisma disecante roto de la arteria cerebelosa anteroinferior: informe de caso y revisión de la literatura","authors":"Taiki Ishikawa ,&nbsp;Hiroshi Kagami ,&nbsp;Mami Ishikawa ,&nbsp;Ken-Ichi Oyama","doi":"10.1016/j.neucir.2025.500712","DOIUrl":"10.1016/j.neucir.2025.500712","url":null,"abstract":"<div><div>Subarachnoid hemorrhage (SAH) caused by a dissecting aneurysm of the anterior inferior cerebellar artery (AICA) is rare. Partial coil embolization of the AICA may be an effective treatment. A 65-year-old woman presented at the emergency room with headache and vomiting for the past five days, after contracting coronavirus disease (COVID-19). Computed tomography (CT) revealed SAH and intraventricular hemorrhage, and the patient was diagnosed with a dissecting aneurysm of the AICA. The patient underwent endovascular surgery, and the AICA was partially occluded using coiling, with no subsequent hearing disturbance, cranial nerve palsy, or infarction. Ventriculoperitoneal shunt surgery was performed for hydrocephalus at 7<!--> <!-->weeks after SAH. The patient was discharged from hospital with no neurological deficit. We reported a rare case of ruptured AICA dissecting aneurysm, which was treated by partial coil embolization without neurological deficit or infarction.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500712"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resultados neurológicos después de corpectomía con injertos autólogos versus cajas de titanio expandibles: un estudio piloto","authors":"Alexis Manuel Portillo-González ,&nbsp;Julio César López-Valdés ,&nbsp;Daniel Alejandro Vega-Moreno ,&nbsp;Óscar Medina-Carrillo ,&nbsp;Abraham Ibarra-De la Torre ,&nbsp;Ulises García-González","doi":"10.1016/j.neucir.2025.500732","DOIUrl":"10.1016/j.neucir.2025.500732","url":null,"abstract":"<div><h3>Background</h3><div>Vertebral corpectomy is a common surgical technique for spinal decompression and fusion. This retrospective pilot study compares the neurological outcomes of corpectomy using autologous bone grafts versus expandable titanium cages.</div></div><div><h3>Methods</h3><div>In this retrospective pilot study of 40 patients, we compared autologous bone grafts versus expandable cages for single- or multi-level corpectomy. We assessed pre- and postoperative mJOA (Modified Japanese Orthopedic Association) scores. To account for baseline imbalances, we performed analysis of covariance (ANCOVA) adjusting for age and preoperative mJOA, and inverse probability of treatment weighting (IPTW) based on propensity scores. Outcomes included postoperative mJOA, <em>Δ</em>mJOA, responder rate (≥2-point improvement), and Hirabayashi recovery rate.</div></div><div><h3>Results</h3><div>Both groups showed significant neurological improvement. Adjusted for preoperative mJOA, the ANCOVA model found that the titanium group presented significantly higher postoperative mJOA scores after adjustment (ANCOVA coefficient<!--> <!-->=<!--> <!-->+2.50, <em>p</em> <!-->=<!--> <!-->0.0007). IPTW-weighted regression showed a trend toward greater neurological improvement with titanium (coefficient<!--> <!-->=<!--> <!-->+1.75, <em>p</em> <!-->=<!--> <!-->0.092), with satisfactory covariate balance. Clinically meaningful recovery was observed in 100% of titanium cases versus 75% of autologous cases (<em>p</em> <!-->=<!--> <!-->0.064). The Hirabayashi recovery rate was also superior with titanium (mean 65.0%) compared to autologous grafts (mean 45.1%).</div></div><div><h3>Conclusion</h3><div>Both techniques provided similar and effective neurological outcomes after corpectomy. Our findings suggest that neurological recovery is more strongly influenced by the preoperative severity of the myelopathy than by the surgical system used. Both are viable options for corpectomy and warrant larger-scale studies.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500732"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relación entre la incidencia del glioblastoma y la radiación natural","authors":"Jose Alberto Escribano Mesa ,&nbsp;Leidy Vanessa Fajardo Güiza ,&nbsp;Cristina Muñoz Romero ,&nbsp;Juan Solivera Vela","doi":"10.1016/j.neucir.2025.500711","DOIUrl":"10.1016/j.neucir.2025.500711","url":null,"abstract":"<div><h3>Objectives</h3><div>To determine the relationship between the impact of high-grade gliomas (HGG) on the population in Córdoba from 2008 to 2019 and the natural radiation background, estimated using radon maps and water origin according to the supply reservoir. Correlation of the results with other prognostic factors. The survival study based on exposure to radon.</div></div><div><h3>Material and methods</h3><div>Observational, cross-sectional, retrospective 11-year study on 365 patients diagnosed with HGG at the Reina Sofía Hospital in Córdoba, exposed or not, to significant radiation, to estimate the impact that this could have on HGG.</div></div><div><h3>Results</h3><div>The incidence of patients diagnosed with glioblastoma multiforme (GBM) in those exposed to radon was 41.6 versus 31.4 cases/100,000 inhabitants in those not exposed (<em>P</em>=.02). The global incidence of HGG was 52.8 cases in those exposed to radon compared with 45 cases/1000 inhabitants in the unexposed ones (<em>P</em>=.12). It was found that 56.8/100,000 were supplied by reservoirs significant for radon, compared to 31.4 cases/100,000 inhabitants that were not (<em>P</em>=.23). A Cox regression was performed, leaving IDH mutation and type of intervention in the model: survival is six times higher in positive IDH mutation (<em>P</em>=.021) and three in surgically intervened (<em>P</em>&lt;.001).</div></div><div><h3>Conclusions</h3><div>Long-term exposure to natural radiation does seem to increase the risk factor for the appearance of GBM. However, other factors influencing such exposure must be considered, such as reliable measurements of radiation and time spent in that place.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 2","pages":"Article 500711"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Riesgo de ictus hemorrágico en pacientes con trastornos psiquiátricos: revisión sistemática y metaanálisis","authors":"Luis Ayerbe ,&nbsp;Quintí Foguet-Boreu ,&nbsp;Ivo Forgnone ,&nbsp;María Pérez-Piñar ,&nbsp;Rohini Mathur ,&nbsp;Salma Ayis","doi":"10.1016/j.neucir.2025.500738","DOIUrl":"10.1016/j.neucir.2025.500738","url":null,"abstract":"<div><h3>Objectives</h3><div>Strong evidence on the risk of haemorrhagic strokes for those with psychiatric conditions may lead to more effective interventions for mental health patients and inform future studies. This systematic review aimed to identify all the studies that compare the risk of haemorrhagic stroke for patients with and without depression, anxiety, schizophrenia, bipolar or personality disorders. It also aimed to provide a summary estimate of the risk, where possible, using meta-analysis.</div></div><div><h3>Methods</h3><div>Electronic searches were conducted in Embase, PsycINFO, PubMED, Scopus and the Web of Science, from database inception to the 11th of March 2025. A Random-effects model to estimate the pooled effect size with 95% confidence intervals was used.</div></div><div><h3>Results</h3><div>Seventeen thousand, two hundred fourteen references were initially identified. Eleven articles were included. Seven of them, five observational and two mendelian randomisation studies, investigated depression. In the meta-analysis depression showed a significant association with an increased risk of haemorrhagic stroke, with pooled HR: 1.28 (1.19-1.38) when only observational studies were included. When mendelian randomisation studies were added the result was a pooled HR: 1.26 (1.08-1.44). The risk of haemorrhagic stroke was increased in one of the three studies that investigated patients with anxiety disorders and in one of the three that looked at patients with schizophrenia. Two studies of bipolar disorder, and one of personality disorders, reported that patients with these conditions do not have an increased risk of haemorrhagic stroke.</div></div><div><h3>Conclusion</h3><div>Patients with depression have an increased risk of haemorrhagic stroke. The association of mental illness with haemorrhagic stroke needs further research.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"37 1","pages":"Article 500738"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145908665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}